Special Issue "Engineering Aptamers for Biomedical Applications"
A special issue of Biomedicines (ISSN 2227-9059).
Deadline for manuscript submissions: closed (31 March 2018).
Interests: RNA therapeutics; delivery of nucleic acid therapeutics; aptamer; tumor microenvironment; signal transduction; microRNA; targeted therapy
Special Issues and Collections in MDPI journals
Special Issue in Cancers: RNA Drugs in Tumor Microenvironment
This Special Issue, “Engineering Aptamers for Biomedical Applications”, will mainly focus on the more recent advances in the development of highly stable and specific aptamers suitable as therapeutic and diagnostic agents.
The introduction of modifications in the nucleic acids backbone, the expansion of genetic variability in nucleobases and the generation of enzymes able to catalyze the synthesis of modified aptamers is revealing as invaluable advantage in the design of aptamer ligands in biomedicine. Aptamers obtained with nucleic acid variants exhibit high stability in circulating fluids, target binding affinity and specificity thus potentially improving their applicability as therapeutics and/or as diagnostic tools.
We cordially invite authors in the field to submit original research or review articles pertaining to this important and fast-progressing field of biomedicine.
Dr. Vittorio de Franciscis
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- aptamer probes and therapeutics
- ODN nanotechnology
- ribozymes/DNAzymes evolution
- combinatorial therapy
- molecular evolution
- expanded genetic