54 Results Found

TAPP (H-Tyr-d-Ala-Phe-Phe-NH₂) is a potent, µ-selective opioid ligand. In order to gain further insights into pharmacophoric features of this tetrapeptide, we have performed a β²-Homo-amino acid (β²hAA) scan of the TAPP sequence. To t...

Background/Objectives: This study aimed to determine the inguinal hernia recurrence rate after transabdominal preperitoneal (TAPP) repair, particularly considering the effect of simultaneous umbilical hernia repair. The secondary aim was to assess wh...

Inguinal hernia is a common condition, with about 30% of men and 6% of women developing this condition throughout their lifetime. Laparoscopic hernia repair procedures have become more and more important lately, due to the advantages of a fast recove...

The rapid development of artificial intelligence technology has made deep neural networks (DNNs) widely used in various fields. DNNs have been continuously growing in order to improve the accuracy and quality of the models. Moreover, traditional data...

Background and Objectives: Inguinal hernia is a common surgical disease. Traditional open herniorrhaphy has been replaced by laparoscopic herniorrhaphy. Nowadays, many attempts at robotic herniorrhaphy have been reported in western countries, but the...

Background. The management of a recurrent inguinal hernia varies depending on multiple factors. In the case of recurrent inguinal hernias after open anterior repair, the laparoscopic approach is recommended. TEP and TAPP procedures are considered to...

Inguinal hernia repair, according to Desarda, is a pure tissue surgical technique using external oblique fascia to reinforce the posterior wall of the inguinal canal. This has provided an impetus for the rethinking of guideline adherence toward minim...

Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide, with over 20 million cases annually. The evolution of hernia surgery has transitioned from tension-based techniques to tension-free approaches, significantly...

Background/Objectives: Recurrent groin and ventral hernias remain technically challenging, and the optimal operative approach is not uniform. This study compared postoperative outcomes after open and minimally invasive repair and examined recurrent i...

(1) Purpose: To compare and evaluate the immediate and long-term results of the use of various hernioplasties for the treatment of inguinal hernias after surgical treatment of prostate cancer; to determine the possibility of performing transabdominal...

Background: After more than 20 years since laparoscopy was proposed as a solution for one of the most common surgical pathologies, inguinal hernia, the choice of an intra- or extraperitoneal approach has remained a highly debated topic. Purpose and o...

Abscisic acid receptors (ABR) play crucial roles in transducing the ABA signaling initiated by osmotic stresses, which has a significant impact on plant acclimation to drought by modulating stress-related defensive physiological processes. We charact...

Cardiovascular diseases (CVDs) have a high disease burden both globally and in South Africa. They have also been found to be temperature-sensitive globally. The association between temperature and CVD morbidity has previously been demonstrated, but l...

Obesity is a chronic epidemic caused by abnormal fat metabolism. As a key digestive enzyme, pancreatic lipase (PL) is an important target for regulating fat metabolism. The inhibitory potential of 5,10,15,20-Tetrakis (4-aminophenyl) porphyrin (TAPP),...

Background/Objectives: The study aims to provide a comprehensive understanding of personalized treatment for patients with inguinal hernias at our hospital, focusing on complications, recurrence rates, and hospitalization duration to optimize treatme...

Cisplatin resistance remains a major impediment to the successful chemotherapy of various solid tumors, including ovarian, lung, and head and neck cancers. Diverse drug delivery systems with photodynamic specificity significantly target diseased cell...

Two new isostructural minerals udinaite and arsenudinaite with the end-member formulae NaMg₄(VO₄)₃ and NaMg₄(AsO₄)₃, respectively, are found in the Arsenatnaya fumarole, Tolbachik volcano, Kamchatka, Russia. They are associated with one another and a...

Nuck’s hydroceles, which develop in a protruding part of the parietal peritoneum into the female inguinal canal, are rare abnormalities and a cause of inguinal swelling, mostly resulting in pain. They appear when this evagination of the parieta...

This study investigates the optimization of structural adhesives used in automotive body manufacturing processes via Thermal Atmospheric Pressure Plasma (TAPP) and Cold Atmospheric Plasma (CAP) surface treatments. Surface preparation of sheet metal p...

During the COVID-19 pandemic, longitudinal serological surveillance was critical to accurately assess the cumulative incidence of COVID-19 and monitor population-level immunity among children. We characterized the epidemiology of COVID-19 among North...

In the original article, there was a mistake in Figure 1B and Section 2 [...]

Advances in technology are likely to provide new approaches to address healthcare disparities for high-risk populations. This study explores the feasibility of a new approach to health disparities research using a multidisciplinary intervention and a...

The current study tests neighborhood (i.e., block group) effects reflective of broken windows theory (i.e., neighborhood, public space, social, housing disorder) on crime. Furthermore, these effects are tested independently on serious (i.e., Part I),...

Vitamin D deficiency or insufficiency is prevalent in childhood cancer patients and survivors after chemotherapy; further studies are needed to investigate the underlying aetiology and effectiveness of vitamin D supplementation in preventing chemothe...

The Health of the Nation Outcome Scales (HoNOS) comprises 12 scales that cover the kinds of problems that may be experienced by working-age adults in contact with specialised mental health services. Drawing on 20 years’ experience in clinical p...

We characterize the overall incidence and risk factors for breakthrough infection among fully vaccinated participants in the North Carolina COVID-19 Community Research Partnership cohort. Among 15,808 eligible participants, 638 reported a positive SA...

This paper looks at the mystical topic of munājāt, or intimate dialogue, typically between a worshipper and their Lord, and how it relates to Ibn al-‘Arabī’s waḥdat al-wujūd (Unity of Being). The paper first work...

Background: The ‘obesity paradox’, whereby obese patients demonstrate better clinical outcomes compared to normal-weight patients, has been reported in acute myocardial infarction, including ST-segment elevation myocardial infarction (STE...

Agriculture is responsible for nearly one-quarter of global greenhouse gas (GHG) emissions, with livestock and poultry systems contributing significantly through methane (CH₄), nitrous oxide (N₂O), and carbon dioxide (CO₂). Achieving net-zero agricul...

Background/Objectives: Given the limitations of traditional approaches to treating existential distress in seriously ill patients, psilocybin-assisted therapy (PAT) has emerged as a promising treatment option. However, weighing up the potential risks...

Protective hard PVD coatings are used to improve the endurance of the tools exposed to repeated impact load, e.g., fine blanking punches. During the fine blanking process, a coated punch repeatedly impacts sheet metal. Thus, the coating which protect...

The widespread use of automated decision processes in many areas of our society raises serious ethical issues with respect to the fairness of the process and the possible resulting discrimination. To solve this issue, we propose a novel adversarial t...

Monitoring SARS-CoV-2 in wastewater has shown to be an effective tool for epidemiological surveillance. More specifically, RNA levels determined with RT-qPCR have been shown to track with the infection dynamics within the population. However, the sur...

In recent years, next generation sequencing (NGS) technology has been widely used for the discovery of novel human papillomavirus (HPV) genotypes, variant characterization and genotyping. Here, we compared the analytical performance of NGS with a com...

Diarrhea contributes significantly to global morbidity and mortality. There is evidence that diarrhea prevalence is associated with ambient temperature. This study aimed to determine if there was an association between ambient temperature and diarrhe...

Covalent organic frameworks (COFs) have emerged as promising electrocatalysts due to their controllable architectures, highly exposed molecular active sites, and ordered structures. In this study, a series of porphyrin-based COFs (TAPP-x-COF) with va...

Diabetes mellitus is a characteristic metabolic disorder with diverse complications. α-Amylase and α-glucosidase, as key digestive enzymes regulating blood glucose, are important targets for diabetes prevention and management through thei...

Children spend a significant proportion of their time at school and in school buildings. A healthy learning environment that supports children should be thermally conducive for learning and working. Here, we aimed to study the relations between indoo...

Inguinal hernia repair represents one of the most frequent pathologies with surgical addressability. From the multitude of surgical procedures, a limited number still keep their indication in the current treatment of hernias. Open surgery, the exclus...

Covalent organic frameworks (COFs) with donor–acceptor (D–A) units are credible photocatalysts for their per-designed structure, inherent porosity, large surface area, splendid stability and so forth. Developing COFs with an excellent pho...

This study presents the spectral characterization of TiO₂ nanoparticles (NPs) functionalized with three porphyrin derivatives: 5,10,15,20-(Tetra-4-aminophenyl) porphyrin (TAPP), 5,10,15,20-(Tetra-4-methoxyphenyl) porphyrin (TMPP), and 5,10,15,20-(Tet...

Combination of capture and simultaneous conversion of CO₂ into valuable chemicals is a fascinating strategy for reducing CO₂ emissions. Therefore, searching for heterogeneous catalysts for efficient catalytic conversion of CO₂ is of great importance...

(1) Background: The sterile latex surgical glove is an important part of protecting both the patient and the surgical team from infections. However, mechanical stress can damage the integrity of the glove material and thus may lead to infections. (2)...

Despite the rapid development of two-dimensional covalent organic frameworks (2D COFs) in recent years, it remains a great challenge to synthesize highly crystalline COF materials. Here, a CNC-assisted approach was adopted to synthesize high crystall...

High air temperature and high humidity, combined with low wind speeds, are common trends in the tropical urban climates, which collectively govern heat-induced health risks and outdoor thermal comfort under the given hygrothermal conditions. The impa...

This study compares some different types of spectral domain transformations for convolutional neural network (CNN)-based land cover classification. A novel approach was proposed, which transforms one-dimensional (1-D) spectral vectors into two-dimens...

Transport of messenger RNA (mRNA) from the nucleus to the cytoplasm is an essential step of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of processing steps, including capping at the 5' ends, splicing and clea...

A facile synthesis of catalytically tunable core-shell CdS-Zn_xMn_1-xS-nanoparticles in conjunction with poly(acrylic acid) (PAA) and porphyrin in an aqueous solution is described in the following: The shell composition of the inorganic nanoparticles i...

Nanocomposite thin films, sensitive to methane at the room temperature (25–30 °C), have been prepared, starting from SnSe₂ powder and Zn(II)-5,10,15,20-tetrakis-(4-aminophenyl)- -porphyrin (ZnTAPP) powder, that were fully characterized by X...

Introduction: For over two decades, abdominal surgical procedures have been safely performed robotically. After the first patent expiration, alternative robotic systems entered the market. The Dexter Robotic System™ is a small-format, modular,...