Spectroscopic Investigations of Novel Pharmaceuticals

Dear Colleagues,

Spectroscopy is a powerful tool in many fields, including pharmaceutics, biomedical sciences, environmental analysis, etc. Spectroscopic techniques have proved to be useful in drug discovery and in the analysis of novel pharmaceuticals. Techniques like FTIR spectroscopy, Raman spectroscopy, laser-induced fluorescence spectroscopy (LIF), NMR spectroscopy, UV-Vis-NIR absorption spectroscopy, and THz spectroscopy aid in the characterization of newly designed molecules by conventional chemical methods or help to identify modifications of known medicines exposed to optical radiation.

Spectroscopy may be employed for analytical studies of novel pharmaceuticals, as well as for the characterization of drug delivery systems (DDSs). Colloidal drug carrier systems (CDCSs) such as micellar solutions, as well as nanoparticle dispersions showing great promise as DDSs, can be successfully investigated by spectroscopic methods. Their very small dimensions lead to superior physical, optical, electrical, and biological properties, making them suitable for a wide range of applications. Laser spectroscopy methods (steady-state absorption and fluorescence spectroscopy, time-resolved phosphorescence spectroscopy) are useful in the detection of reactive oxygen species (ROS), in photodynamic therapy, or in antimicrobial phototherapy.

This Special Issue aims to gather spectroscopy studies in pharmaceutical and biomedical sciences, characterizing novel pharmaceuticals or drug delivery systems. Researchers are welcome to submit their studies on the following spectroscopic method applications (but not limited to these):

1. Vibrational spectroscopy (FTIR, Raman spectroscopy);
2. UV-Vis-NIR absorption spectroscopy;
3. Flash photolysis and transient absorption spectroscopy;
4. Steady-state and time-resolved fluorescence spectroscopy;
5. Fluorescence resonance energy transfer (FRET);
6. Time-resolved phosphorescence spectroscopy, ROS detection;
7. Photoacoustic and THz spectroscopy;
8. Liquid chromatography-mass spectrometry

Dr. Angela Staicu
Dr. Adriana Smarandache
Dr. Tatiana Tozar
Dr. Andra Dinache
Guest Editors

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