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139 Results Found

  • Article
  • Open Access
2 Citations
2,391 Views
16 Pages

29 September 2023

For series cascade processes with a time delay, such as the first-order with time-delay (FOTD) process, the integral with time-delay (ITD) process, second-order integral with time-delay (SOITD) process, and unstable first-order with time-delay (UFOTD...

(This article belongs to the Special Issue Intelligent Manufacturing Systems and Applications in Industry 4.0)
  • Article
  • Open Access
16 Citations
6,077 Views
25 Pages

Design and Development of Complex-Order PI-PD Controllers: Case Studies on Pressure and Flow Process Control

  • Muhammad Najmi Bin Roslan,
  • Kishore Bingi,
  • P. Arun Mozhi Devan and
  • Rosdiazli Ibrahim

This article examines the performance of the proposed complex-order, conventional and fractional-order controllers for process automation and control in process plants. The controllers are compared regarding disturbance rejection and set-point tracki...

(This article belongs to the Section Control and Systems Engineering)
  • Article
  • Open Access
11 Citations
3,651 Views
18 Pages

24 August 2024

PI-PD controllers have superior performance compared to traditional PID controllers, especially for controlling unstable and integrating industrial processes with time delays. However, computing the four tuning parameters of this type of controller i...

(This article belongs to the Special Issue Advanced Control Techniques for Power Converter and Drives)
  • Article
  • Open Access
3 Citations
1,531 Views
14 Pages

4 March 2025

This study proposes an optimized approach to enhance the performance of the Weighted Geometric Center (WGC) method for stabilizing time-delay systems, which has applications in industrial process control, robotics, and high-order dynamic systems. The...

(This article belongs to the Special Issue Design and Analysis of Adaptive Identification and Control)
  • Article
  • Open Access
17 Citations
2,709 Views
49 Pages

Efficient Frequency Management for Hybrid AC/DC Power Systems Based on an Optimized Fuzzy Cascaded PI−PD Controller

  • Awadh Ba Wazir,
  • Sultan Alghamdi,
  • Abdulraheem Alobaidi,
  • Abdullah Ali Alhussainy and
  • Ahmad H. Milyani

19 December 2024

A fuzzy cascaded PI−PD (FCPIPD) controller is proposed in this paper to optimize load frequency control (LFC) in the linked electrical network. The FCPIPD controller is composed of fuzzy logic, proportional integral, and proportional derivative...

(This article belongs to the Section F2: Distributed Energy System)
  • Article
  • Open Access
31 Citations
4,541 Views
20 Pages

MPPT of PEM Fuel Cell Using PI-PD Controller Based on Golden Jackal Optimization Algorithm

  • Ahmed M. Agwa,
  • Tarek I. Alanazi,
  • Habib Kraiem,
  • Ezzeddine Touti and ,
  • Abdulaziz Alanazi and
  • Dhari K. Alanazi
  • + 1 author+ 0 author

14 September 2023

Subversive environmental impacts and limited amounts of conventional forms of energy necessitate the utilization of renewable energies (REs). Unfortunately, REs such as solar and wind energies are intermittent, so they should be stored in other forms...

(This article belongs to the Special Issue Biomimicry for Optimization, Control, and Automation)
  • Article
  • Open Access
61 Citations
4,380 Views
34 Pages

14 November 2022

Frequency, voltage, and power flow between different control zones in an interconnected power system are used to determine the standard quality of power. Therefore, the voltage and frequency control in an IPS is of vital importance to maintaining rea...

(This article belongs to the Section A1: Smart Grids and Microgrids)
  • Article
  • Open Access
63 Citations
6,829 Views
30 Pages

Load Frequency Control and Automatic Voltage Regulation in a Multi-Area Interconnected Power System Using Nature-Inspired Computation-Based Control Methodology

  • Tayyab Ali,
  • Suheel Abdullah Malik,
  • Ibrahim A. Hameed,
  • Amil Daraz and ,
  • Hana Mujlid and
  • Ahmad Taher Azar
  • + 1 author+ 0 author

26 September 2022

The stability control of nominal frequency and terminal voltage in an interconnected power system (IPS) is always a challenging task for researchers. The load variation or any disturbance affects the active and reactive power demands, which badly inf...

(This article belongs to the Special Issue Smart Grid Analytics for Sustainability and Urbanization in Big Data)
  • Article
  • Open Access
2 Citations
812 Views
39 Pages

2 June 2026

Reliable load frequency control (LFC) in interconnected hybrid power systems remains challenging in the presence of nonlinear operating conditions, random demand variations, and parametric uncertainty. This study proposes a PSO-based LFC framework fo...

(This article belongs to the Special Issue Challenges and Innovations in Stability and Control of Power Systems)
  • Article
  • Open Access
19 Citations
4,928 Views
16 Pages

25 December 2022

This paper presents a controller design technique for cascade control systems based on the grey wolf optimization (GWO) algorithm. In the proposed control scheme, the proportional-integral-proportional-derivative (PI-PD) controller structure is used...

(This article belongs to the Topic Analysis and Controls of Time-Delay Systems with Perturbations: Theory and Application)
  • Article
  • Open Access
43 Citations
3,536 Views
32 Pages

Development of Slime Mold Optimizer with Application for Tuning Cascaded PD-PI Controller to Enhance Frequency Stability in Power Systems

  • Slim Abid,
  • Ali M. El-Rifaie,
  • Mostafa Elshahed,
  • Ahmed R. Ginidi and ,
  • Abdullah M. Shaheen,
  • Ghareeb Moustafa and
  • Mohamed A. Tolba
  • + 2 authors+ 0 author

10 April 2023

Multi-area power systems (MAPSs) are highly complex non-linear systems facing a fundamental issue in real-world engineering problems called frequency stability problems (FSP). This paper develops an enhanced slime mold optimization algorithm (ESMOA)...

(This article belongs to the Special Issue Advanced Control Theory with Applications)
  • Article
  • Open Access
8 Citations
3,403 Views
16 Pages

1 July 2024

This research aims to apply Artificial Intelligence (AI) methods, specifically Artificial Immune Systems (AIS), to design an optimal control strategy for a multivariable control plant. Two specific industrial control approaches are investigated: I-PD...

(This article belongs to the Topic AI and Computational Methods for Modelling, Simulations and Optimizing of Advanced Systems: Innovations in Complexity)
  • Article
  • Open Access
7 Citations
2,046 Views
20 Pages

2 November 2023

In a smart grid (SG) system with load uncertainties and the integration of variable solar and wind energies, an effective frequency control strategy is necessary for generation and load balancing. Cyberattacks are emerging threats, and SG systems are...

(This article belongs to the Section F: Engineering and Materials)
  • Article
  • Open Access
6 Citations
3,909 Views
17 Pages

Robust Fractional-Order PI/PD Controllers for a Cascade Control Structure of Servo Systems

  • Vo Lam Chuong,
  • Ngo Hong Nam,
  • Le Hieu Giang and
  • Truong Nguyen Luan Vu

In this paper, a cascade control structure is suggested to control servo systems that normally include a servo motor in coupling with two kinds of mechanism elements, a translational or rotational movement. These kinds of systems have high demands fo...

(This article belongs to the Special Issue Applications of Fractional-Order Systems to Automatic Control)
  • Article
  • Open Access
32 Citations
2,955 Views
24 Pages

Applications of Novel Combined Controllers for Optimizing Grid-Connected Hybrid Renewable Energy Systems

  • Fatima Menzri,
  • Tarek Boutabba,
  • Idriss Benlaloui,
  • Larbi Chrifi-Alaoui and ,
  • Abdulaziz Alkuhayli,
  • Usama Khaled and
  • Mohamed Metwally Mahmoud
  • + 2 authors+ 0 author

9 August 2024

Hybrid renewable energy systems (HRES) integrating solar, wind, and storage technologies offer enhanced efficiency and reliability for grid-connected applications. However, existing control methods often struggle with maintaining DC voltage stability...

  • Article
  • Open Access
18 Citations
4,140 Views
22 Pages

Optimal Cascade Non-Integer Controller for Shunt Active Power Filter: Real-Time Implementation

  • Hoda Nikkhah Kashani,
  • Reza Rouhi Ardeshiri,
  • Meysam Gheisarnejad and
  • Mohammad-Hassan Khooban

1 April 2022

Active power filters (APFs) are used to mitigate the harmonics generated by nonlinear loads in distribution networks. Therefore, due to the increase of nonlinear loads in power systems, it is necessary to reduce current harmonics. One typical method...

(This article belongs to the Topic Multi-Energy Systems)
  • Article
  • Open Access
11 Citations
4,857 Views
36 Pages

27 November 2024

This study presents the design, simulation, and comparative analysis of three advanced control strategies applied to a 3-Degree-of-Freedom (DoF) robot manipulator. The controllers investigated are a variant from the Computed Torque Control family, a...

  • Article
  • Open Access
11 Citations
2,620 Views
21 Pages

An Optimized Fuzzy Based Control Solution for Frequency Oscillation Reduction in Electric Grids

  • Hina Maqbool,
  • Adnan Yousaf,
  • Rao Muhammad Asif,
  • Ateeq Ur Rehman and ,
  • Elsayed Tag Eldin,
  • Muhammad Shafiq and
  • Habib Hamam
  • + 2 authors+ 0 author

23 September 2022

The demand for uninterruptible electricity supply is increasing, and the power engineering sector has started researching alternative solutions. Distributed generation (DG) dissemination into the electric grid to cope with the accelerating demand for...

  • Article
  • Open Access
405 Views
27 Pages

During actual vehicle operation, working conditions are highly complex, involving both body roll induced by steering centrifugal force and attitude fluctuations caused by random road irregularities or sudden lateral wind disturbances. By optimizing t...

(This article belongs to the Section Systems & Control Engineering)
  • Article
  • Open Access
2 Citations
1,790 Views
26 Pages

A Classic and Fuzzy Parallel Hybrid Controller of PD-PI Type for a Two-Wheeled Self-Balancing Robot

  • Ricardo Rojas-Galván,
  • Josué A. Romero-Moreno,
  • Roberto V. Carrillo-Serrano,
  • José R. García-Martínez and ,
  • Trinidad Martínez-Sánchez,
  • Mario Trejo-Perea,
  • José G. Ríos-Moreno and
  • Juvenal Rodríguez-Reséndiz
  • + 3 authors+ 0 author

Two-wheeled self-balancing robots (TWSBRs) are difficult to control because they are nonlinear, unstable, and underactuated, particularly when balance, velocity regulation, and line tracking must be achieved simultaneously. This paper proposes a hybr...

(This article belongs to the Special Issue Intelligent Mechatronic Systems: Advances in Automation, Control, and Robotics)
  • Article
  • Open Access
9 Citations
1,677 Views
49 Pages

30 September 2025

The increasing integration of renewable energy sources (RES) and rising energy demand have created challenges in maintaining stability in interconnected power systems, particularly in terms of frequency, voltage, and tie-line power. While traditional...

(This article belongs to the Special Issue Artificial Intelligence and Optimization in Engineering Applications)
  • Feature Paper
  • Article
  • Open Access
14 Citations
3,447 Views
18 Pages

An Experimental Tuning Approach of Fractional Order Controllers in the Frequency Domain

  • Isabela Birs,
  • Silviu Folea,
  • Ovidiu Prodan,
  • Eva Dulf and
  • Cristina Muresan

31 March 2020

Fractional calculus has been used intensely in recent years in control engineering to extend the capabilities of the classical proportional–integral–derivative (PID) controller, but most tuning techniques are based on the model of the pro...

(This article belongs to the Special Issue Control and Automation)
  • Article
  • Open Access
12 Citations
4,031 Views
24 Pages

1 June 2023

This paper presents a new fractional-order proportional-integral, (PI)λ (FO[PI]) type structure to investigate the load frequency control (LFC) problem. In the literature, some controllers’ extensive tuning options may slow or complicate...

  • Article
  • Open Access
11 Citations
4,088 Views
25 Pages

30 June 2022

Sliding pressure control is a well-known method of controlling supercritical power plants that improves energy efficiency and reduces pressure dynamic stresses. This paper presents a novel approach for developing a supercritical cleaner coal power pl...

(This article belongs to the Section Energy Sustainability)
  • Article
  • Open Access
3 Citations
2,407 Views
19 Pages

Simplified Model Characterization and Control of an Unmanned Surface Vehicle

  • Aldo Lovo-Ayala,
  • Roosvel Soto-Diaz,
  • Carlos Andres Gutierrez-Martinez,
  • Jose Fernando Jimenez-Vargas and ,
  • Javier Jiménez-Cabas and
  • Jose Escorcía-Gutierrez
  • + 1 author+ 0 author

This study presents the modeling and control of the unmanned surface vehicle (USV) SABALO. Two models were built, one based on a transfer function matrix and another based on state variables, and from these models, two control strategies were develop...

(This article belongs to the Special Issue Advanced Research in Guidance, Navigation, and Control for Autonomous Surface Vehicle)
  • Article
  • Open Access
2,645 Views
59 Pages

Manufacture of a 4-Degree-of-Freedom Robot to Support an IRB 120 Robot

  • Ricardo Balcazar,
  • José de Jesús Rubio,
  • Mario Alberto Hernandez,
  • Jaime Pacheco and ,
  • Adrian-Josue Guel-Cortez,
  • Genaro Ochoa,
  • Enrique Garcia,
  • Alejandro Zacarías and
  • Gabriela Saavedra González
  • + 4 authors+ 0 author

28 November 2024

In this work, we present the construction and control of a four-degrees-of-freedom (DOF) manipulator aimed at addressing one of the key challenges faced by the Academy-Industry Cooperation Center (CCAI): the need for mechatronic equipment to support...

(This article belongs to the Section Actuators for Robotics)
  • Article
  • Open Access
7 Citations
2,930 Views
29 Pages

Metaheuristic Optimization Algorithm Based Cascaded Control Schemes for Nonlinear Ball and Balancer System

  • Farhan Zafar,
  • Suheel Abdullah Malik,
  • Tayyab Ali,
  • Amil Daraz and ,
  • Atif M. Alamri,
  • Salman A. AlQahtani and
  • Farkhunda Bhatti
  • + 2 authors+ 0 author

29 January 2024

The ball and balancer system is a popular research platform for studying underactuated mechanical systems and developing control algorithms. It is a well-known two-dimensional balancing problem that has been addressed by a variety of controllers. Thi...

(This article belongs to the Special Issue Design and Control of Complex and Intelligent Systems)
  • Article
  • Open Access
14 Citations
6,661 Views
19 Pages

Energy-Efficient Control of a Gas Turbine Power Generation System

  • Marwan Al-Shami,
  • Omar Mohamed and
  • Wejdan Abu Elhaija

Gas turbines are used in the energy sectors as propulsion and power generation technologies. Despite technological advances in power generation and the emergence of numerous energy resources, gas turbine technology remains important due to its flexib...

(This article belongs to the Topic Zero Carbon Vehicles and Power Generation)
  • Article
  • Open Access
9 Citations
2,031 Views
39 Pages

An Optimal Two-Stage Tuned PIDF + Fuzzy Controller for Enhanced LFC in Hybrid Power Systems

  • Saleh Almutairi,
  • Fatih Anayi,
  • Michael Packianather and
  • Mokhtar Shouran

14 October 2025

Ensuring reliable power system control demands innovative architectural solutions. This research introduces a fault-tolerant hybrid parallel compensator architecture for load frequency control (LFC), combining a Proportional–Integral–Deri...

(This article belongs to the Special Issue Advanced Control Strategies for Renewable Energy Systems and Sustainable Development)
  • Article
  • Open Access
9 Citations
1,438 Views
27 Pages

13 September 2024

An active stabiliser bar significantly enhances the anti-roll capabilities of vehicles. The control strategy is a crucial factor in enabling the active stabiliser bar to function effectively. This paper investigates an active disturbance rejection co...

(This article belongs to the Section AI-Enabled Process Engineering)
  • Article
  • Open Access
12 Citations
5,251 Views
11 Pages

23 November 2020

Background: There have been several pathologic data that support an association between postural instability (PI) and autonomic dysfunction in Parkinson’s disease (PD). The purpose of this study was to investigate the correlation of PI and auto...

(This article belongs to the Section Clinical Neurology)
  • Feature Paper
  • Article
  • Open Access
7 Citations
3,494 Views
10 Pages

Postural Instability and Risk of Falls in Patients with Parkinson’s Disease Treated with Deep Brain Stimulation: A Stabilometric Platform Study

  • Giorgio Leodori,
  • Marco Santilli,
  • Nicola Modugno,
  • Michele D’Avino and ,
  • Maria Ilenia De Bartolo,
  • Andrea Fabbrini,
  • Lorenzo Rocchi,
  • Antonella Conte,
  • Giovanni Fabbrini and
  • Daniele Belvisi
  • + 5 authors+ 0 author

25 August 2023

Postural instability (PI) in Parkinson’s disease (PD) exposes patients to an increased risk of falls (RF). While dopaminergic therapy and deep brain stimulation (DBS) improve motor performance in advanced PD patients, their effects on PI and RF...

(This article belongs to the Special Issue Behavioral and Neural Mechanisms Underlying Sensory–Motor Integration)
  • Article
  • Open Access
49 Citations
8,112 Views
13 Pages

19 December 2014

Effects of platycodin D (PD) on the proliferation, apoptosis and PI3K/Akt signaling pathway of human glioma U251 cells were investigated. Glioma U251 cells were treated with PD at final concentrations of 0, 16.3, 40.8, 81.6, 163.2 μM, and inhibition...

(This article belongs to the Section Medicinal Chemistry)
  • Article
  • Open Access
14 Citations
4,350 Views
12 Pages

Ozone Therapy as an Adjuvant in the Treatment of Periodontitis

  • Abdulaziz Alsakr,
  • Khalid Gufran,
  • Abdullah Saad Alqahtani,
  • Mohammed Alasqah and ,
  • Banna Alnufaiy,
  • Hanadi Ghurmallah Alzahrani,
  • Ali Ayidh Alahmari,
  • Faisal Khaled Alhumaidani,
  • Rakan Khaled Alhumaidani and
  • Mishari Jameel Althobiti
  • + 5 authors+ 0 author

14 November 2023

The current study aimed to assess the efficacy of ozone therapy in the treatment of stage II and stage III periodontitis. This prospective split-mouth study selected patients who were diagnosed with either stage II or stage III periodontitis. All pat...

(This article belongs to the Special Issue Clinical Research of Novel Therapeutic Approaches in Dentistry)
  • Article
  • Open Access
94 Views
23 Pages

3 November 2026

Speed ripple attenuation in geared flexible drives requires control of synchronous components and residual fluctuations within an existing embedded control architecture. This paper develops a five-state delay-coordinate predictive damping controller...

(This article belongs to the Topic Intelligent Mechatronics System Modeling, Control and Evaluation)
  • Article
  • Open Access
23 Citations
4,029 Views
39 Pages

Different Fuzzy Control Configurations Tuned by the Bees Algorithm for LFC of Two-Area Power System

  • Mokhtar Shouran,
  • Fatih Anayi,
  • Michael Packianather and
  • Monier Habil

17 January 2022

This study develops and implements a design of the Fuzzy Proportional Integral Derivative with filtered derivative mode (Fuzzy PIDF) for Load Frequency Control (LFC) of a two-area interconnected power system. To attain the optimal values of the propo...

(This article belongs to the Section F: Electrical Engineering)
  • Article
  • Open Access
5 Citations
3,998 Views
12 Pages

10 November 2023

Background: Primary dysmenorrhea (PD) is one of the most common diseases in women of reproductive age. Our aim was to examine whether a twice-weekly thirty-minute exercise intervention could result in a difference in the pulsatility index (PI) of the...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
5 Citations
3,554 Views
11 Pages

Experimental Control of a Methanol Catalytic Membrane Reformer

  • Alejandro Cifuentes,
  • Maria Serra,
  • Ricardo Torres and
  • Jordi Llorca

6 November 2023

A simple proportional integral (PI) controller with scheduled gain has been developed and implemented in a catalytic membrane reactor (CMR) to obtain pure hydrogen from a methanol steam reforming process. The controller is designed to track the setpo...

(This article belongs to the Special Issue Hydrogen Production and Storage, 2nd Edition)
  • Article
  • Open Access
1 Citations
2,802 Views
16 Pages

13 October 2025

Background/Objectives: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms such as tremor, bradykinesia, rigidity, and postural instability. In the absence of disease-modifying therapies, exercis...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
9 Citations
2,402 Views
16 Pages

12 September 2023

In order to solve the problem that the parameters of traditional proportional–integral (PI) control are not easy to adjust, an iterative learning control (ILC) technique for a DC/DC power converter is proposed in this paper. Firstly, we have develope...

(This article belongs to the Section D: Energy Storage and Application)
  • Article
  • Open Access
2 Citations
1,072 Views
37 Pages

Parkinson’s disease (PD) and acute kidney injury (AKI) are two conditions with increasing prevalence and severe systemic complications and consequences. This research examines the combined neuroprotective and nephroprotective properties of thre...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Article
  • Open Access
3 Citations
3,495 Views
18 Pages

Evaluation of Chelator-to-Antibody Ratio on Development of 89Zr-iPET Tracer for Imaging of PD-L1 Expression on Tumor

  • Shih-Chuan Tsai,
  • Shiou-Shiow Farn,
  • Wei-Lin Lo,
  • Fang-Yu Ou Yang and ,
  • Yong-Ching Kang,
  • Liang-Cheng Chen,
  • Kuo-Ting Chen,
  • Jiunn-Wang Liao,
  • Jui-Yin Kung and
  • Feng-Yun J. Huang
  • + 6 authors+ 1 author

5 December 2023

89Zr-iPET has been widely used for preclinical and clinical immunotherapy studies to predict patient stratification or evaluate therapeutic efficacy. In this study, we prepared and evaluated 89Zr-DFO-anti-PD-L1-mAb tracers with varying chelator-to-an...

(This article belongs to the Section Molecular Pharmacology)
  • Article
  • Open Access
10 Citations
4,205 Views
13 Pages

Changes in Brain Energy and Membrane Metabolism in Glioblastoma following Chemoradiation

  • Astrid Ellen Grams,
  • Stephanie Mangesius,
  • Ruth Steiger,
  • Ivan Radovic and ,
  • Andreas Rietzler,
  • Lisa Maria Walchhofer,
  • Malik Galijašević,
  • Julian Mangesius,
  • Martha Nowosielski and
  • Elke Ruth Gizewski
  • + 7 authors+ 2 authors

1 December 2021

Brain parenchyma infiltration with glioblastoma (GB) cannot be entirely visualized by conventional magnetic resonance imaging (MRI). The aim of this study was to investigate changes in the energy and membrane metabolism measured with phosphorous MR s...

(This article belongs to the Special Issue Recent Advancements in the Surgical Treatment of Brain Tumors)
  • Article
  • Open Access
5 Citations
3,140 Views
9 Pages

Clinical Evaluation of Short Tuberosity Implants among Type 2 Diabetic and Non-Diabetic Patients: A 5 Year Follow-Up

  • Huda I. Tulbah,
  • Abdulaziz Alsahhaf,
  • Hamad S. AlRumaih,
  • Fahim Vohra and
  • Tariq Abduljabbar

19 October 2022

Aim: To assess clinical and radiographic parameters including bleeding on probing (BoP); probing depth (PD), plaque index (PI) and crestal bone loss (CBL) around short tuberosity implants (STI) supporting fixed partial dentures in patients with Type...

  • Article
  • Open Access
7 Citations
1,907 Views
22 Pages

Tandem Mass Tags Quantitative Proteomics Reveal the Mechanism by Which Paeoniflorin Regulates the PI3K/AKT and BDNF/CREB Signaling Pathways to Inhibit Parkinson’s Disease

  • Zhen Feng,
  • Chang Jin,
  • Yue Zhang,
  • Huiming Xue and ,
  • Yongxing Ai,
  • Jing Wang,
  • Meizhu Zheng and
  • Dongfang Shi
  • + 3 authors+ 0 author

Paeoniflorin (PF), a monomeric compound extracted from the dry roots of Paeonia lactiflora, has been widely used in the treatment of nervous system diseases, marking it as a critical formula in Parkinson’s disease (PD). However, the action of P...

(This article belongs to the Special Issue Recent Advances of Natural Products in Chemical and Biological Aspects)
  • Article
  • Open Access
4 Citations
2,938 Views
11 Pages

Association of Self-Rated Pain with Clinical Peri-Implant Parameters and Cytokine Profile in Smokers and Never Smokers with and without Peri-Implantitis

  • Faris A. Alshahrani,
  • Firas K. Alqarawi,
  • Montaser N. Alqutub,
  • Abdulrahman M. AlMubarak and ,
  • Eman M. AlHamdan,
  • Samar Al-Saleh,
  • Paras Ahmad,
  • Fahim Vohra and
  • Tariq Abduljabbar
  • + 4 authors+ 0 author

16 June 2021

To examine the association between self-perceived pain (SPP), clinical and radiographic peri-implant parameters, and biomarker levels among smokers and never smokers with and without peri-implantitis. Sixty individuals (20 smokers with peri-implantit...

(This article belongs to the Special Issue Celebrating Applied Sciences Reaches 20,000 Articles Milestone: Invited Papers in "Applied Dentistry and Oral Sciences" Section)
  • Article
  • Open Access
3 Citations
2,299 Views
20 Pages

Oral Administration of Astrocyte-Targeted Natural Antioxidants Suppress NOX4-Driven Neuroinflammation and Restore Hippocampal Neurogenesis in MPTP-Induced Parkinson’s Disease Mouse Model

  • Miri Jo,
  • Chae-Young Kim,
  • Kayoung Ko,
  • Seohee Choi and ,
  • Jinhye Kim,
  • Kyuhee Park,
  • Isaac Jinwon Yi,
  • Sang-Seop Nahm,
  • Kiyoung Kim and
  • Sun-Shin Yi
  • + 6 authors+ 1 author

23 December 2025

Background/Objectives: Astrocytic redox-inflammatory signaling has been implicated in Parkinson’s disease (PD) pathology and may constrain hippocampal neurogenesis. We previously identified an astrocytic NOX4–MPO–OPN axis associated...

(This article belongs to the Special Issue Impact of Nutritional Supplementation on Cognition and Neuroinflammation)
  • Article
  • Open Access
36 Citations
6,664 Views
16 Pages

Regulatory miRNA–mRNA Networks in Parkinson’s Disease

  • Bruno Lopes Santos-Lobato,
  • Amanda Ferreira Vidal and
  • Ândrea Ribeiro-dos-Santos

6 June 2021

Parkinson’s disease (PD) is the second-most common neurodegenerative disease, and its pathophysiology is associated with alpha-synuclein accumulation, oxidative stress, mitochondrial dysfunction, and neuroinflammation. MicroRNAs are small non-coding...

(This article belongs to the Collection Regulatory Functions of microRNAs)
  • Article
  • Open Access
12 Citations
5,310 Views
12 Pages

In Situ PD-L1 Expression in Oral Squamous Cell Carcinoma Is Induced by Heterogeneous Mechanisms among Patients

  • Yutaro Kondo,
  • Susumu Suzuki,
  • Shoya Ono,
  • Mitsuo Goto and ,
  • Satoru Miyabe,
  • Tetsuya Ogawa,
  • Hiromi Tsuchida,
  • Hideaki Ito,
  • Taishi Takahara and
  • Toru Nagao
  • + 9 authors+ 4 authors

The expression of programmed death ligand-1 (PD-L1) is controlled by complex mechanisms. The elucidation of the molecular mechanisms of PD-L1 expression is important for the exploration of new insights into PD-1 blockade therapy. Detailed mechanisms...

(This article belongs to the Special Issue Advances in Molecular Mechanism of Head and Neck Cancer)
  • Systematic Review
  • Open Access
6 Citations
3,153 Views
40 Pages

Potential Impact of Microbial Variations After Peri-Implantitis Treatment on Peri-Implant Clinical, Radiographic, and Crevicular Parameters: A Systematic Review

  • Federica Di Spirito,
  • Massimo Pisano,
  • Maria Pia Di Palo,
  • Flora Salzano and ,
  • Antonio Rupe,
  • Antonino Fiorino and
  • Carlo Rengo
  • + 2 authors+ 0 author

17 December 2024

Objectives: This systematic review evaluated concomitant trends in microbial (total biofilm load and pre-dominant pathogens’ counts) and clinical, radiographic, and crevicular variations following (any) peri-implantitis treatment in partially v...

(This article belongs to the Special Issue Oral Implantology and Rehabilitation)

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