This paper considers C.S. Lewis’ “doctrine of objective value” in two of his major works, The Abolition of Man and The Discarded Image. Lewis uses the Chinese name Tao, albeit with an incomplete understanding of its origins, for the...
Rainfall disaggregation is a key challenge in hydrology, especially in regions with limited high-resolution records. This study applies the Random Bartlett–Lewis Rectangular Pulse Model to four regions of Hellas to generate hourly rainfall from...
Temporal variability of rainfall is extreme in the rangelands of northern Australia and occurs at annual, decadal, and even longer timescales. To maintain long-term productivity of the rangelands of northern Australia under highly variable rainfall c...
Lewy body dementia (LBD) is an often misdiagnosed and mistreated neurodegenerative disorder clinically characterized by the emergence of neuropsychiatric symptoms followed by motor impairment. LBD falls within an undefined range between Alzheimer&rsq...
Asthma is an allergic disease that causes severe infiltration of leukocytes into the lungs. Leukocyte infiltration is mediated by the binding of sialyl Lewis X (sLex) glycans present on the leukocytes to E-and P-selectins present on the endothelial c...
Functional foods enriched with plant polyphenol anthocyanins attract particular attention due to their health-promoting properties, including antitumor activity. We evaluated the effects of a grain diet rich in anthocyanins in a mouse model of Lewis...
Almost 10% of the global population suffers from chronic kidney disease (CKD). The inexistence of a therapeutic to restore renal function motivates the scientific community to search for new treatments. The 5/6 nephrectomy (Nx) rat model is widely us...
Antrodan, a unique protein-bound polysaccharide derived from the fungal mycelia of Antrodia cinnamomea, has been reported to exhibit antitumor and anti-metastatic effects on Lewis lung carcinoma (LLC) cells through direct action and immunomodulation...
Efficient CO2 hydrogenation by frustrated Lewis pairs requires balancing H2 activation with subsequent delivery of proton and hydride equivalents to CO2. Here, we investigate this interplay in a systematic 2 × 2 series of intramolecular boron/n...
The study of the surface thermodynamic properties of solid materials is primordial for the determination of the dispersive surface energy, polar enthalpy of adsorption and Lewis’s acid base properties of solid particles. The inverse gas chromat...
Interleukin-18 (IL-18) can effectively activate natural killer (NK) cells and induce large concentrations of interferon-γ (IFN-γ). In healthy humans, IL-18 binding protein (IL-18BP) can inhibit the binding of IL-18 to IL-18R and counterac...
The thermal surface properties of graphenes and carbon materials are of crucial importance in the chemistry of materials, chemical engineering, and many industrial processes. Background: The determination of these surface properties is carried out us...
The surface thermodynamic properties of polymers and copolymers modified by supramolecular structures are used in several industrial processes, such as selective adsorption, paints, coatings, colloids, and adhesion applications. Background: Inverse g...
The influence of Linus Pauling on the understanding of chemical bonding is critically examined. Pauling deserves credit for presenting a connection between the quantum theoretical description of chemical bonding and Gilbert Lewis’s classical bonding...
The dispersive and polar properties of materials, and especially of polymers and copolymers, play an important role in several engineering applications implying their surfaces and interfaces. The surface energetic properties of poly(styrene-co-butadi...
The linear diblock copolymer polystyrene-b-poly(4-vinylpyridine) (PS-P4VP) is an important copolymer recently used in many applications such as optoelectronics, sensors, catalysis, membranes, energy conversion, energy storage devices, photolithograph...
The objective of this paper is to present a mathematical formalism that states a bridge between physics and psychology, concretely between analytical dynamics and personality theory, in order to open new insights in this theory. In this formalism, en...
This paper presents a methodological approach for the evaluation of the thermal behavior of cementitious porous media with/without integrated latent-heat thermal energy storage (LHTES). To achieve this goal, the Lewis-Nielsen model has been calibrate...
In this article, the Lewis model was considered for the soybean drying process by new fractional differential operators to analyze the estimated time in
Background/Objectives: Combining chemotherapy with local magnetic hyperthermia (MHT) is promising because heating tumor tissue can increase cell damage, sensitize cells to cytostatic drugs, impair DNA repair, and change tumor microenvironment permeab...
The London dispersive and polar surface properties of solid materials are very important in many chemical processes, such as adsorption, coatings, catalysis, colloids, and mechanical engineering. One of the materials, a styrene–divinylbenzene c...
The main aim of this paper was to analyze the sensitivity of the five infiltration equations (Kostiakov, Kostiakov–Lewis, Philip, Horton and SCS) and their coefficients to various ponding depths and initial soil moisture under different irrigat...
Disease modeling in non-human subjects is an essential part of any clinical research. To gain proper understanding of the etiology and pathophysiology of any disease, experimental models are required to replicate the disease process. Due to the huge...
This article demonstrates a dispersed-monolayer graphene-doped polymer/silica hybrid Mach–Zehnder interferometer (MZI) thermal optical switch with low-power consumption and fast response. The polymer/silica hybrid MZI structure reduces the power cons...
Progressive accumulation of α-Synuclein (αSyn) in Lewy bodies (LBs) and loss of dopaminergic (DA) neurons are the hallmark pathological features of Parkinson’s disease (PD). Although currently available in vitro and in vivo models h...
Non-small-cell lung cancer (NSCLC) makes up 80–85% of lung cancer diagnoses. Lung cancer patients undergo surgical procedures, chemotherapy, and/or radiation. Chemotherapy and radiation can induce deleterious systemic side effects, particularly withi...
Selaginella doederleinii Hieron has been traditionally used as a folk antitumor herbal medicine in China. In this paper, the phytochemical components of the total biflavonoids extract from S. doederleinii were studied by using high-performance liquid...
In the current literature, many non-covalent interaction (NCI) donors have been proposed that can potentially catalyze Diels-Alder (DA) reactions. In this study, a detailed analysis of the governing factors in Lewis acid and non-covalent catalysis of...
The remarkable efficacy of cancer immunotherapy has been established in several tumor types. Of the various immunotherapies, PD-1/PD-L1 inhibitors are most extensively used in the treatment of many cancers in clinics. These inhibitors restore the sup...
Since lung cancer remains a leading cause of cancer-related mortality, effective adjunct strategies against this disease are needed. This study evaluated an extract prepared from organically cultivated Capsicum annuum treated with deep-seawater-deriv...
Although the combination of radiotherapy and immunotherapy has proven to be effective in lung cancer treatment, it may not be sufficient to fully activate the antitumor immune response. Here, we investigated whether entinostat, a histone deacetylase...
A comprehensive thermodynamic and molecular-level investigation of adsorption on MgY and NH4Y zeolites is presented using inverse gas chromatography at infinite dilution (IGC-ID), combined with a Hamaker-based formalism and an extended five-parameter...
α-Synuclein oligomers are thought to play an important role in the pathogenesis of dementia with Lewy bodies (DLB). There is no effective cure for DLB at present. Previously, we demonstrated that in APP- and tau-transgenic mice, oral or intranasal ri...
Lung cancer is the most prevalent cancer worldwide. Despite advances in surgery and immune-chemotherapy, the therapeutic outcome remains poor. In recent years, the anticancer properties of natural compounds, along with their low toxic side effects, h...
Understanding tumor–host immune interactions and the mechanisms of lung cancer response to immunotherapy is crucial. Current preclinical models used to study this often fall short of capturing the complexities of human lung cancer and lead to i...
This study deals with the preparation of activated carbon (CDSP) from date seed powder (DSP) by chemical activation to eliminate polyaromatic hydrocarbon—PAHs (naphthalene—C10H8) from synthetic wastewater. The chemical activation process was carried...
This review puts the development of molecular modeling methods in the context of their applications to zeolitic active sites. We attempt to highlight the utmost necessity of close cooperation between theory and experiment, resulting both in advances...
In Parkinson’s disease, aggregates of α-synuclein within Lewy bodies and Lewy neurites represent neuropathological hallmarks. However, the cellular and molecular mechanisms triggering oligomeric and fibrillary α-synuclein aggregation are not fully un...
Here we present the numerical methods, applications, and comparisons with observations and previous studies. It includes numerical analyses of shallow water equations, Sun’s scheme, and nonlinear model simulations of a dam break, solitary Rossb...
This review provides a critical assessment of the current state of affairs regarding the solvation thermodynamics involving mixed-solvent systems. It focuses specifically on (i) its rigorous molecular-based foundations, (ii) the underlying connection...
Alpha-synuclein (αSyn) is one of the most abundant proteins in the nervous system and is currently associated with devastating synucleinopathies, yet its biology extends far beyond this. In this review, we suggest that αSyn-driven disease...
There are many major causes of cancer death, including metastasis of cancer. Dihydroaustrasulfone alcohol, which is isolated from marine coral, has shown antioxidant activity, but has not been reported to have an anti-cancer effect. We first discover...
The Lewis basicity of selected organic bases, modeled by the enthalpies of adduct formation between gaseous BF3 and bases in dichloromethane (DCM) solution, is critically examined. Although experimental enthalpies for a large number of molecules have...
The catalytic deoxygenation mechanism of fatty acid esters on a Lewis acid site of ZSM-5 zeolite was elucidated via density functional theory (DFT) by using a methyl butyrate (MB) as the model compound for fatty acid esters. The configurations of the...
In order to synthesize chemical filters for the selective removal of volatile fluorides, commercial magnesium fluoride MgF2 with high specific surface area (HSA) was investigated. The amount of -OH groups substituting fluorine is not negligible, part...
The predictions of turbulent burning velocity parameterizations for non-unity Lewis number flames have been assessed based on a single-step chemistry Direct Numerical Simulation (DNS) database of premixed Bunsen flames for different values of charact...
The empirical Lewis picture of the chemical bond dominates the view chemists have of molecules, of their stability and reactivity. Within the mathematical framework of quantum mechanics, all this chemical information is hidden in the many-particle wa...
Lewis’ theory of multiple scattering has been modeled as a random walk on a unit sphere for calculating the multiple scattering angular distribution of charged particles, which is more intuitive and mathematically simpler. This formalism can le...
Lewis Y antigen, a glycan highly expressed on most epithelial cancers, was targeted for cancer treatment but lacked satisfactory results in some intractable and refractory cancers. Thus, it is highly desirable to develop an effective therapy against...
This work reports the results of the ultrasound-assisted hydrothermal synthesis of two sets of V2O5 dispersed on SBA-15 and Zr doped SBA-15 catalysts used for the oxidation of dibenzothiophene (DBT) in a model diesel via the combination of oxidation,...
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