Skip to Content
You are currently on the new version of our website. Access the old version .

121,172 Results Found

  • Article
  • Open Access
6 Citations
4,138 Views
13 Pages

Validation of an Italian Questionnaire of Adherence to the Ketogenic Dietary Therapies: iKetoCheck

  • Lenycia de Cassya Lopes Neri,
  • Monica Guglielmetti,
  • Valentina De Giorgis,
  • Ludovica Pasca and ,
  • Martina Paola Zanaboni,
  • Claudia Trentani,
  • Elena Ballante,
  • Serena Grumi,
  • Cinzia Ferraris and
  • on behalf of the KDTs Delphi Validation Study Group
  • + 6 authors+ 1 author

26 August 2023

Ketogenic dietary therapies (KDTs) are an effective and safe non-pharmacological treatment for drug-resistant epilepsy, but adherence can be challenging for both patients and caregivers. In Europe, there are no adequate tools to measure it other than...

(This article belongs to the Section Food Nutrition)
  • Feature Paper
  • Article
  • Open Access
8 Citations
4,453 Views
13 Pages

Core Competencies for Gerontogeriatric Nursing: A Validation Study

  • Maria José Catalão,
  • Helena Arco,
  • Nuno Carrajola,
  • Maria de Lurdes Almeida and ,
  • Hugo Neves and
  • João Tavares
  • + 1 author+ 0 author

Background: As the aging population grows, facing multifaceted health challenges and escalating care costs, equipping newly graduated nurses with the requisite skills for high-quality gerontogeriatric care becomes crucial. This study assesses the psy...

  • Article
  • Open Access
13 Citations
5,301 Views
19 Pages

Validity and Reproducibility of a Self-Administered Food Frequency Questionnaire for the Assessment of Sugar Intake in Middle-Aged Japanese Adults

  • Rieko Kanehara,
  • Atsushi Goto,
  • Ayaka Kotemori,
  • Nagisa Mori and ,
  • Ari Nakamura,
  • Norie Sawada,
  • Junko Ishihara,
  • Ribeka Takachi,
  • Yukari Kawano and
  • for the JPHC FFQ Validation Study Group
  • + 7 authors+ 2 authors

5 March 2019

We evaluated the validity and reproducibility of estimated sugar intakes using a food frequency questionnaire (FFQ) among middle-aged Japanese adults in the Japan Public Health Centre-Based Prospective (JPHC) study. In subsamples of the JPHC study (C...

(This article belongs to the Special Issue Advancement in Dietary Assessment and Self-Monitoring Using Technology)
  • Article
  • Open Access
6 Citations
2,956 Views
15 Pages

Cultural Adaptation and Psychometric Properties of the Trust Me Scale—Italian Version: A Validation Study

  • Dhurata Ivziku,
  • Rosario Caruso,
  • Marzia Lommi,
  • Gianluca Conte and ,
  • Arianna Magon,
  • Alessandro Stievano,
  • Gennaro Rocco,
  • Ippolito Notarnicola,
  • Maddalena De Maria and
  • Anna De Benedictis
  • + 7 authors+ 2 authors

Background: The Trust Me Scale is a widely used instrument to measure trust in healthcare providers. However, no Italian version of the scale exists yet, limiting its use in Italian-speaking populations. The aim of this study is to translate and vali...

(This article belongs to the Special Issue Research, Education, Workforce, and Regulation to Transforming Nursing Practice and Leadership: The Future of Nursing)
  • Article
  • Open Access
2 Citations
3,467 Views
18 Pages

A Validation Study of the COPSOQ III Greek Questionnaire for Assessing Psychosocial Factors in the Workplace

  • Aristomenis Kotsakis,
  • Demetris Avraam,
  • Maria Malliarou,
  • Elpidoforos S. Soteriades and ,
  • Constantinos Halkiopoulos,
  • Michael Galanakis and
  • Michael Sfakianakis
  • + 2 authors+ 0 author

12 August 2025

Background: Over the past two decades, the Copenhagen Psychosocial Questionnaire (COPSOQ) has been established as a valid instrument to measure psychosocial stress at work. Currently, the COPSOQ international network is responsible for monitoring and...

(This article belongs to the Special Issue Patient Safety and Psychosocial Risk in the Workplace)
  • Article
  • Open Access
40 Citations
7,977 Views
9 Pages

Psychometric Proprieties of a Mobile Application to Measure the Craniovertebral Angle a Validation and Reliability Study

  • Tomas Gallego-Izquierdo,
  • Enrique Arroba-Díaz,
  • Gema García-Ascoz,
  • María del Alba Val-Cano and ,
  • Daniel Pecos-Martin and
  • Roberto Cano-de-la-Cuerda
  • + 1 author+ 0 author

The aim of this study was to assess the psychometric properties of the mobile application forward head posture in terms of validity, inter- and intra-rater reliability, minimum detectable change, sensitivity, and specificity to measure craniovertebra...

(This article belongs to the Special Issue Technological Innovation in Clinical Healthcare and Health Management)
  • Article
  • Open Access
1,456 Views
16 Pages

Development and Validation of a Nursing Care Protocol for Laser Therapy in Pressure Injuries: Methodological Study

  • Beatrice de Barros Lima,
  • Alessandra Conceição Leite Funchal Camacho,
  • Harlon França de Menezes,
  • Suelem Frian Couto Dias and
  • Richardson Augusto Rosendo da Silva

Pressure injuries remain highly prevalent in hospital and home settings, particularly among elderly patients, intensive care unit patients, and individuals with impaired mobility, generating significant healthcare and economic impacts. Although low-l...

(This article belongs to the Special Issue Advancing Nursing Practice in Chronic Condition Care)
  • Article
  • Open Access
3,678 Views
9 Pages

Diagnostic Performance of AI-Assisted Software in Sports Dentistry: A Validation Study

  • André Júdice,
  • Diogo Brandão,
  • Carlota Rodrigues,
  • Cátia Simões and ,
  • Gabriel Nogueira,
  • Vanessa Machado,
  • Luciano Maia Alves Ferreira,
  • Daniel Ferreira,
  • Luís Proença and
  • José João Mendes
  • + 7 authors+ 2 authors

1 October 2025

Artificial Intelligence (AI) applications in sports dentistry have the potential to improve early detection and diagnosis. We aimed to validate the diagnostic performance of AI-assisted software in detecting dental caries, periodontitis, and tooth we...

(This article belongs to the Special Issue Artificial Intelligence in Biomedical Engineering: Challenges and Developments)
  • Article
  • Open Access
11 Citations
8,897 Views
9 Pages

A Computer Vision-Based Application for the Assessment of Head Posture: A Validation and Reliability Study

  • Andoni Carrasco-Uribarren,
  • Xavier Marimon,
  • Flora Dantony,
  • Sara Cabanillas-Barea and ,
  • Alejandro Portela,
  • Luis Ceballos-Laita and
  • Albert Massip-Álvarez
  • + 2 authors+ 0 author

19 March 2023

As its name implies, the forward head position (FHP) is when the head is further forward of the trunk than normal. This can cause neck and shoulder tension, as well as headaches. The craniovertebral angle (CVA) measured with 2D systems such as Kinove...

(This article belongs to the Special Issue Artificial Intelligence in Medicine and Healthcare)
  • Article
  • Open Access
10 Citations
7,709 Views
15 Pages

Preliminary Validation Study of the Intrinsic Religious Motivation Scale and the Centrality of Religiosity Scale for the Portuguese Population

  • Pedro Araújo,
  • Sara Gomes,
  • Diogo Guedes Vidal,
  • Hélder Fernando Pedrosa e Sousa and ,
  • Maria Alzira Pimenta Dinis and
  • Ângela Leite
  • + 1 author+ 0 author

Religion is a construct widely present in most people’s lives. Religious motivations, either intrinsic or extrinsic, as well as religious centrality, are crucial aspects of religion. In the Portuguese population, there are no validated instruments to...

(This article belongs to the Special Issue Strategies for Coping with Daily Stress and Related Educational and Psychosocial Factors)
  • Article
  • Open Access
2,620 Views
9 Pages

Psychometric Properties of the European Evaluation of Vertigo Scale (EEV) for a Spanish-Speaking Population: A Validation Study

  • María Alharilla Montilla-Ibáñez,
  • Rafael Lomas-Vega,
  • María del Carmen López-Ruiz,
  • Ángeles Díaz-Fernández and ,
  • Alfonso Javier Ibáñez-Vera,
  • Ana Belén Peinado-Rubia,
  • Esteban Obrero-Gaitán and
  • Ana Sedeño-Vidal
  • + 3 authors+ 0 author

Background/Objectives: The objective of this study was to validate the Spanish version of the European Evaluation of Vertigo (EEV) and analyse its test–retest reliability, standard error of measurement (SEM), minimum detectable change (MDC), co...

(This article belongs to the Section Balance)
  • Article
  • Open Access
7 Citations
4,795 Views
11 Pages

4 October 2021

Nursing students perform clinical training in a variety of clinical practice fields, so their rights are important. Efforts are needed to accurately identify and measure the awareness of nursing students’ rights. This study aimed to develop and evalu...

(This article belongs to the Section Nursing)
  • Article
  • Open Access
8 Citations
3,819 Views
11 Pages

Validation Evidence for the Children’s Eating Behaviour Questionnaire (CEBQ) in Brazil: A Cross-Sectional Study

  • Marina Zanette Peuckert,
  • Camila Ospina Ayala,
  • Rita Mattiello,
  • Thiago Wendt Viola and ,
  • Marthina Streda Walker,
  • Ana Maria Pandolfo Feoli and
  • Caroline Abud Drumond Costa
  • + 2 authors+ 0 author

28 February 2025

Background: Eating behavior is influenced by intrinsic and extrinsic factors from early infancy, shaping an individual’s relationship with food. Tools such as the Children’s Eating Behaviour Questionnaire (CEBQ) were designed to evaluate...

(This article belongs to the Section Pediatric Nutrition)
  • Article
  • Open Access
11 Citations
5,658 Views
11 Pages

Caries Detection and Classification in Photographs Using an Artificial Intelligence-Based Model—An External Validation Study

  • Elisabeth Frenkel,
  • Julia Neumayr,
  • Julia Schwarzmaier,
  • Andreas Kessler and ,
  • Nour Ammar,
  • Falk Schwendicke,
  • Jan Kühnisch and
  • Helena Dujic
  • + 3 authors+ 0 author

14 October 2024

Objective: This ex vivo diagnostic study aimed to externally validate a freely accessible AI-based model for caries detection, classification, localisation and segmentation using an independent image dataset. It was hypothesised that there would be n...

(This article belongs to the Special Issue Deep Learning in Medical and Biomedical Image Processing)
  • Article
  • Open Access
6 Citations
3,828 Views
18 Pages

26 April 2022

Attention has been given to the experience of individuals undergoing assisted reproductive techniques. However, only recent literature has focused on the spiritual journey triggered by such an event and highlighted the nurses and midwives’ role...

  • Article
  • Open Access
5 Citations
2,591 Views
23 Pages

Development and Validation of HSPiP- and Optimization-Assisted Method to Analyze Tolterodine Tartrate in Pharmacokinetic Study

  • Tosh Patil,
  • Mohd Usman Mohd Siddique,
  • Madhav Shelke,
  • Mohhammad Ramzan and ,
  • Mrunali Patil and
  • Mudassar Shahid
  • + 1 author+ 0 author

4 October 2024

A new approach was applied for the development of a precise, simple, and economic analytical process for the accurate analysis of tolterodine tartrate (TOT) in its bulk and tablet using HSPiP- and quality by design (QbD)-assisted methods. The HSPiP p...

(This article belongs to the Special Issue Modeling, Simulation, Control, and Optimization of Processes)
  • Article
  • Open Access
2 Citations
3,185 Views
12 Pages

Verifying the Japanese Version of Pediatric Delirium and Withdrawal Syndrome Assessment Scale: SOS-PD Validation Study for Iatrogenic Withdrawal Syndrome

  • Yujiro Matsuishi,
  • Haruhiko Hoshino,
  • Yuki Enomoto,
  • Takahiro Kido and ,
  • Nobutake Shimojo,
  • Bryan J. Mathis,
  • Erwin Ista and
  • Yoshiaki Inoue
  • + 3 authors+ 0 author

17 March 2025

Background: Iatrogenic withdrawal syndrome (IWS) poses a significant clinical challenge in pediatric intensive care units (PICUs) within Japan. Despite the existing availability of tools to assess pain and delirium, a validated instrument specificall...

(This article belongs to the Special Issue Nursing Management in Pediatric Intensive Care)
  • Article
  • Open Access
6 Citations
2,859 Views
12 Pages

Validation of the FACETS-OF-PPC as an Outcome Measure for Children with Severe Neurological Impairment and Their Families—A Multicenter Prospective Longitudinal Study

  • Sophie Pelke,
  • Julia Wager,
  • Benedikt B. Claus,
  • Kathrin Stening and ,
  • Boris Zernikow and
  • Mandira Reuther
  • + 1 author+ 0 author

11 October 2021

Outcome measurement in pediatric palliative care (PPC) is receiving increasing attention. The FACETS-OF-PPC, a multidimensional outcome measure for children with severe neurological impairment, has been developed and partly validated. This study aime...

(This article belongs to the Collection Pediatric Palliative Care Update)
  • Article
  • Open Access
2 Citations
1,680 Views
18 Pages

Translation, Cross-Cultural Adaptation, and Psychometric Validation of the TeamSTEPPS® Teamwork Attitudes Questionnaire: A Methodological Study

  • Leonor Velez,
  • Patrícia Costa,
  • Ana Rita Figueiredo,
  • Mafalda Inácio and ,
  • Paulo Cruchinho,
  • Elisabete Nunes and
  • Pedro Lucas
  • + 2 authors+ 0 author

15 January 2026

Background: Teamwork and effective communication are widely recognized as essential pillars for the safety and quality of healthcare. However, in Portugal, no validated instrument had previously been available to assess healthcare professionals&rsquo...

(This article belongs to the Section Nursing Education and Leadership)
  • Article
  • Open Access
4 Citations
5,713 Views
18 Pages

Translation and Linguistic Validation of a Swedish Study-Specific Questionnaire for Use among Norwegian Parents Who Lost a Child to Cancer

  • Hilde-Kristin Vegsund,
  • Toril Rannestad,
  • Trude Reinfjell,
  • Unni Karin Moksnes and ,
  • Alexandra Eilegård Wallin and
  • Mary-Elizabeth Bradley Eilertsen
  • + 1 author+ 0 author

3 October 2018

Background: Research is needed on how to help cancer-bereaved parents, as they are considered to be a vulnerable population and they are at risk of developing ill health following the loss of a child to cancer. The purpose of the present study was to...

  • Article
  • Open Access
10 Citations
10,024 Views
19 Pages

Accuracy of Heart Rate Measurement Under Transient States: A Validation Study of Wearables for Real-Life Monitoring

  • Catharina Nina Van Oost,
  • Federica Masci,
  • Adelien Malisse,
  • An-Marie Schyvens and ,
  • Brent Peters,
  • Hélène Dirix,
  • Veerle Ross,
  • Geert Wets,
  • An Neven and
  • Jean-Marie Aerts
  • + 6 authors+ 1 author

13 October 2025

Wearable devices are increasingly used for health and stress monitoring, yet their accuracy under dynamic, real-world conditions remains uncertain. This study validated the heart rate measurement accuracy of one chest-worn device (Zephyr BioHarness 3...

(This article belongs to the Section Wearables)
  • Article
  • Open Access
10 Citations
5,734 Views
15 Pages

Translation and First Pilot Validation Study of the “Undergraduate Nursing Student Academic Satisfaction Scale” Questionnaire to the Spanish Context

  • María Dolores Guerra-Martín,
  • Alejandro Cano-Orihuela,
  • Raúl Martos-García and
  • José Antonio Ponce-Blandón

Satisfaction helps nursing students to develop skills and improve their academic performance, hence the importance of assessing it by means of a reliable instrument. The objective was to translate and culturally adapt the “Undergraduate Nursing...

(This article belongs to the Special Issue Nursing and Society)
  • Article
  • Open Access
6 Citations
2,231 Views
15 Pages

Development and Validation of an Educational Book on Self-Management in Inflammatory Bowel Disease Based on Patient Preferences and Expert Opinions: A Methodological Study

  • Narges Norouzkhani,
  • Ali Bahari,
  • Mahbobeh Faramarzi,
  • Javad Shokri Shirvani and ,
  • Saeid Eslami and
  • Hamed Tabesh
  • + 1 author+ 0 author

13 December 2023

Background: Self-management education resources for inflammatory bowel disease (IBD) using concepts remain infrequent. We aim to describe the development and evaluation process of educational material for self-management in IBD based on patient prefe...

(This article belongs to the Special Issue Multidisciplinary Approaches to Inflammatory Bowel Disease Management)
  • Article
  • Open Access
3 Citations
3,244 Views
17 Pages

Six-Gene Signature for Differential Diagnosis and Therapeutic Decisions in Non-Small-Cell Lung Cancer—A Validation Study

  • Radoslaw Charkiewicz,
  • Anetta Sulewska,
  • Piotr Karabowicz,
  • Grzegorz Lapuc and ,
  • Alicja Charkiewicz,
  • Marcin Kraska,
  • Joanna Pancewicz,
  • Malgorzata Lukasik,
  • Miroslaw Kozlowski and
  • Wieslawa Niklinska
  • + 9 authors+ 4 authors

Non-small-cell lung cancer (NSCLC) poses a challenge due to its heterogeneity, necessitating precise histopathological subtyping and prognostication for optimal treatment decision-making. Molecular markers emerge as a potential solution, overcoming t...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Article
  • Open Access
2 Citations
1,663 Views
12 Pages

18 August 2025

Background: Effective doctor–patient communication is essential for high-quality care, especially for patients with chronic conditions requiring hemodialysis. However, there is a lack of validated tools in the Malay language to measure this com...

  • Article
  • Open Access
6 Citations
10,691 Views
13 Pages

A Validation Study on the Frequency and Natural History of Miscarriages Using the Spanish Primary Care Database BIFAP

  • Sara Sanchez Ortiz,
  • Consuelo Huerta,
  • Ana Llorente-García,
  • Paloma Ortega and ,
  • Paloma Astasio and
  • Lucía Cea-Soriano
  • + 1 author+ 0 author

(1) Background: There is a major gap of knowledge towards the natural history of miscarriages in electronic medical records. We aimed to calculate the frequency of miscarriages using data from BIFAP database. (2) Methods: We identified all pregnancy...

(This article belongs to the Special Issue Diagnosis and Treatment for Women's Health)
  • Article
  • Open Access
4 Citations
3,312 Views
14 Pages

Psychometric Properties of the Italian Version of the Short-Form Supportive Care Needs Survey Questionnaire (SCNS-SF34-It): A Multicenter Validation Study

  • Anita Zeneli,
  • Paolo Leombruni,
  • Marco Miniotti,
  • Emanuela Scarpi and ,
  • Marco Maltoni,
  • Sara Cavalieri,
  • Valentina Legni,
  • Cristina Nanni,
  • Mihaiela Tarca and
  • Sandra Montalti
  • + 6 authors+ 1 author

27 January 2024

This study aimed to evaluate psychometric properties of the Italian version of the Short-Form Supportive Care Needs Survey Questionnaire (SCNS-SF34) in a cancer population. A multicenter prospective observational study was carried out in outpatient a...

  • Study Protocol
  • Open Access
529 Views
21 Pages

Content Refinement and Multicenter Validation of the ELIGES Patient Experience Questionnaire Focused on Nursing Care During Hospitalization: Study Protocol

  • Noelia Navamuel-Castillo,
  • Josep-Oriol Casanovas-Marsal,
  • Ángel Boned-Galán,
  • Ana Belén Hernández-Ruiz and ,
  • Nieves López-Ibort and
  • Ana Gascón-Catalán
  • + 1 author+ 0 author

9 September 2026

Background: Patient experience has become a key component of healthcare quality assessment and improvement. Although its importance is increasingly recognized, there is a lack of standardized instruments specifically designed to assess patient experi...

  • Article
  • Open Access
35 Citations
4,185 Views
14 Pages

Ocular Surface Microbiota in Naïve Keratoconus: A Multicenter Validation Study

  • Carlos Rocha-de-Lossada,
  • Cosimo Mazzotta,
  • Federico Gabrielli,
  • Filomena Tiziana Papa and ,
  • Carmen Gómez-Huertas,
  • Celia García-López,
  • Facundo Urbinati,
  • Rahul Rachwani-Anil,
  • María García-Lorente and
  • Davide Borroni
  • + 8 authors+ 3 authors

4 October 2023

In the field of Ophthalmology, the mNGS 16S rRNA sequencing method of studying the microbiota and ocular microbiome is gaining more and more weight in the scientific community. This study aims to characterize the ocular microbiota of patients diagnos...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
2 Citations
2,079 Views
11 Pages

A Validation Study of cT-Categories in the Swedish National Urinary Bladder Cancer Register—Norrland University Hospital

  • Erik Wiberg,
  • Andrés Vega,
  • Victoria Eriksson,
  • Viqar Banday and ,
  • Johan Svensson,
  • Elisabeth Eriksson,
  • Staffan Jahnson and
  • Amir Sherif
  • + 3 authors+ 0 author

20 July 2023

Background: In Sweden, all patients with urinary bladder cancer (UBC) are recorded in the Swedish National Register for Urinary Bladder Cancer (SNRUBC). The purpose of this study was to validate the registered clinical tumour categories (cT-categorie...

(This article belongs to the Section Methodology, Drug and Device Discovery)
  • Article
  • Open Access
3,061 Views
13 Pages

Development and Validation of an LC-MS/MS Assay to Quantitate 2′,4′,6′-Trihydroxyacetophenone in Rat and Dog Plasma and its Application to a Pharmacokinetic Study

  • Hee Jo Yoo,
  • Se-Jung Hwang,
  • Jeong-Hun Lee,
  • Wang-Seob Shim and ,
  • Yun-Woong Choi,
  • Sang Min Cho,
  • Eun Kyoung Chung,
  • Jun-Bom Park and
  • Kyung-Tae Lee
  • + 4 authors+ 0 author

23 September 2020

In the present study, a simple, rapid, and reliable bioanalytical method was developed using liquid chromatography with tandem-mass spectrometry (LC-MS/MS) to quantify 2′,4′,6′-trihydroxyacetophenone (THAP) in rat and dog plasma wit...

(This article belongs to the Section Analytical Chemistry)
  • Article
  • Open Access
26 Citations
3,298 Views
13 Pages

External Validation of Surrogate Indices of Fatty Liver in the General Population: The Bagnacavallo Study

  • Francesco Giuseppe Foschi,
  • Fabio Conti,
  • Marco Domenicali,
  • Pierluigi Giacomoni and ,
  • Alberto Borghi,
  • Vittoria Bevilacqua,
  • Lucia Napoli,
  • Dante Berardinelli,
  • Mattia Altini and
  • Bagnacavallo Study Group
  • + 12 authors+ 7 authors

1 February 2021

We externally validated the fatty liver index (FLI), the lipid accumulation product (LAP), the hepatic steatosis index (HSI), and the Zhejiang University index (ZJU) for the diagnosis of fatty liver (FL) and non-alcoholic fatty liver disease (NAFLD)...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
9 Citations
2,100 Views
12 Pages

Diagnostic Performance of Serum Leucine-Rich Alpha-2-Glycoprotein 1 in Pediatric Acute Appendicitis: A Prospective Validation Study

  • Javier Arredondo Montero,
  • Raquel Ros Briones,
  • Amaya Fernández-Celis,
  • Natalia López-Andrés and
  • Nerea Martín-Calvo

Introduction: Leucine-rich alpha-2-glycoprotein 1(LRG-1) is a human protein that has shown potential usefulness as a biomarker for diagnosing pediatric acute appendicitis (PAA). This study aims to validate the diagnostic performance of serum LRG-1 in...

(This article belongs to the Special Issue Pancreatic, Liver, Biliary Tract and Intestinal Diseases: Pathogenesis, Diagnostics and Therapy)
  • Article
  • Open Access
515 Views
37 Pages

9 September 2026

This study proposes a source-study-aware validation framework to estimate the shear capacity of stirrup-free steel-fiber-reinforced concrete corbels and assess the reliability and generalizability of machine-learning models in structural engineering....

(This article belongs to the Section Building Structures)
  • Article
  • Open Access
1 Citations
2,783 Views
15 Pages

Translation, Cross-Cultural Adaptation, and Psychometric Validation of the Authentic Nurse Leadership Questionnaire for the Portuguese Context: A Methodological Study

  • Pedro Lucas,
  • Ana Gaspar,
  • Paulo Cruchinho,
  • Mafalda Inácio and ,
  • Ana Rita Figueiredo,
  • Luísa Dias,
  • Paula Agostinho,
  • João Oliveira,
  • Marie Giordano-Mulligan and
  • Patrícia Costa
  • + 6 authors+ 1 author

9 October 2025

Background: Authentic leadership is characterized by the authenticity and self-awareness of the leader, who acts with transparency and promotes positive outcomes in clinical practice and team management. In Portugal, there isn’t a tool availabl...

  • Study Protocol
  • Open Access
5 Citations
3,645 Views
10 Pages

24 February 2022

Newly diagnosed breast cancer (BC) patients with clinical T1–T2 N0 disease undergo sentinel-lymph-node (SLN) biopsy, although most of them have a benign SLN. The pilot noninvasive lymph node staging (NILS) artificial neural network (ANN) model...

(This article belongs to the Special Issue Intelligent Data Analysis for Medical Diagnosis)
  • Article
  • Open Access
10 Citations
2,589 Views
13 Pages

Modification and Validation of the System Causability Scale Using AI-Based Therapeutic Recommendations for Urological Cancer Patients: A Basis for the Development of a Prospective Comparative Study

  • Emily Rinderknecht,
  • Dominik von Winning,
  • Anton Kravchuk,
  • Christof Schäfer and ,
  • Marco J. Schnabel,
  • Stephan Siepmann,
  • Roman Mayr,
  • Jochen Grassinger,
  • Christopher Goßler and
  • Matthias May
  • + 14 authors+ 9 authors

11 November 2024

The integration of artificial intelligence, particularly Large Language Models (LLMs), has the potential to significantly enhance therapeutic decision-making in clinical oncology. Initial studies across various disciplines have demonstrated that LLM-...

(This article belongs to the Special Issue Shaping the Future of Oncology: The Role of Generative AI in Clinical and Research Environments)
  • Article
  • Open Access
2 Citations
3,631 Views
11 Pages

Adaptation of the Taiwan Version of the Supportive and Palliative Care Indicators Tool (SPICT-TW) and Its Association with Six-Month Mortality: A Multi-Center Validation Study in Older People

  • Jung-Yu Liao,
  • Hsiao-Ting Chang,
  • Jen-Kuei Peng,
  • Scott A. Murray and ,
  • Chien-Yi Wu,
  • Hsien-Cheng Chang,
  • Chia-Ming Li,
  • Shao-Yi Cheng,
  • Wei-Zhe Tseng and
  • Ping-Jen Chen
  • + 9 authors+ 4 authors

1 November 2024

Background: The Supportive and Palliative Care Indicators Tool (SPICT) was developed for identifying, in a timely manner, patients who may benefit from supportive and palliative care for better treatment review, care-plan discussion, and end-of-life...

(This article belongs to the Special Issue Healthcare Practice in Community)
  • Article
  • Open Access
2 Citations
1,298 Views
23 Pages

Placement-Dependent Accuracy of a Smartphone-Based Sensor Application Compared to an Accelerometer-Based System for Measuring Physical Activity in Healthy Adults: A Validation Study

  • Mette Garval,
  • Louise Pedersen,
  • Lars M. Pedersen,
  • Ane Kathrine W. d. J. Nielsen and ,
  • David H. Christiansen,
  • Jeppe Lange and
  • Stefan Wagner
  • + 2 authors+ 0 author

25 March 2026

Accurately monitoring physical activity, including stationary cycling on an exercise bike, is important in managing chronic diseases and rehabilitation after lower limb surgery. This study aimed to validate a new smartphone-based sensor application (...

(This article belongs to the Special Issue Ambient, Wearable Sensor, Gateway Support for Telemonitoring, Telehealth and Telemedicine Systems)
  • Article
  • Open Access
8 Citations
4,202 Views
18 Pages

This study developed a simple, rapid, reproducible, and analytical method using liquid chromatography and electrospray ionization (ESI) with tandem mass spectrometry (LC-MS/MS) to simultaneously quantify pentoxifylline (PTX), its pharmacological acti...

(This article belongs to the Section Advanced Separation Science in Biomedical Research and Clinical Applications)
  • Article
  • Open Access
4 Citations
1,321 Views
11 Pages

Postoperative Geriatric Nutritional Risk Index as a Determinant of Tolerance to S-1 Adjuvant Chemotherapy After Curative Surgery for Pancreatic Ductal Adenocarcinoma: A Cohort Study with External Validation

  • Naotake Funamizu,
  • Akimasa Sakamoto,
  • Shozo Mori,
  • Miku Iwata and ,
  • Mikiya Shine,
  • Chihiro Ito,
  • Mio Uraoka,
  • Yoshitomo Ueno,
  • Kei Tamura and
  • Yuzo Umeda
  • + 8 authors+ 3 authors

26 April 2025

S-1 adjuvant chemotherapy (AC) is the standard treatment for pancreatic ductal adenocarcinoma (PDAC) after curative surgery in Japan. Our prior research suggested that a lower postoperative geriatric nutritional risk index (GNRI) predicts S-1 discont...

(This article belongs to the Section Clinical Research in Cancer)
  • Study Protocol
  • Open Access
244 Views
33 Pages

Development and Psychometric Validation of a Knowledge, Attitudes, and Practices Questionnaire on Pulmonary Embolism and Its Modifiable Risk Factors (PE-KAP-RO): Protocol for a Cross-Sectional Study in Adults from Western Romania

  • Carina Gîb,
  • Alina Anton,
  • Raluca-Andreea Jupâneanț,
  • Andreea-Adriana Neamțu and ,
  • Laura Maghiar,
  • Teodora Maria Bodog,
  • Yasmina Laza,
  • Teodor-Andrei Maghiar,
  • Emanuel Ionuț Poplicean and
  • Daniel Florin Lighezan
  • + 8 authors+ 3 authors

23 October 2026

Background/Objectives: Venous thromboembolism (VTE), whose most severe manifestation is pulmonary embolism (PE), is the third most common acute cardiovascular disorder, and many of its risk factors≠—obesity, physical inactivity, smoking, and...

(This article belongs to the Special Issue Advancing Population Health Literacy: Validated Tools, Innovative Measures, and Digital Approaches for Empowering Public Health)
  • Article
  • Open Access
30 Citations
5,837 Views
13 Pages

28 December 2021

Options for monitoring sports have been continuously developed by using activity trackers to determine almost all vital and movement parameters. The aim of this study was to validate heart rate and distance measurements of two activity trackers (Pola...

(This article belongs to the Special Issue Smartphones and Wearable Sensors for Monitoring Heart Rate and Heart Rate Variability)
  • Article
  • Open Access
1 Citations
1,801 Views
16 Pages

Validation of the G-Force Platform for Isometric Tests in Physically Active Young Adults: A Pilot Study

  • Víctor Garrido-Osorio,
  • Héctor Fuentes-Barría,
  • Raúl Aguilera-Eguía,
  • Ángel Roco-Videla and ,
  • Mauricio Quidel,
  • Luis Romero-Vera,
  • Jorge Leschot-Gatica,
  • Sebastián Sanhueza-González,
  • Alberto Ñancupil-Andrade and
  • Diana Rojas-Gómez
  • + 6 authors+ 1 author

22 November 2025

Objectives: To evaluate the validity, accuracy, and reliability of the G-Force force platform during isometric tests, through comparison with a gold-standard force platform in physically active young adults. Methods: Nine physically active participan...

(This article belongs to the Special Issue Exercise, Fitness, Human Performance and Health: 2nd Edition)
  • Article
  • Open Access
5 Citations
2,064 Views
11 Pages

C-Reactive Protein-to-Albumin Ratio as a Predictive Indicator for Evaluating Tolerability in S-1 Adjuvant Chemotherapy after Curative Surgery for Pancreatic Cancer: An External Validation Cohort Study

  • Naotake Funamizu,
  • Shozo Mori,
  • Akimasa Sakamoto,
  • Miku Iwata and ,
  • Mikiya Shine,
  • Chihiro Ito,
  • Mio Uraoka,
  • Yoshitomo Ueno,
  • Kei Tamura and
  • Yasutsugu Takada
  • + 7 authors+ 2 authors

1 October 2024

Background: S-1 in adjuvant chemotherapy (AC) administration after pancreatic cancer (PC) surgery has been standardized in Japan. The Ehime study confirmed that a postoperative higher C-reactive protein-to-albumin ratio (CAR) value predicted the risk...

(This article belongs to the Special Issue Oncology: State-of-the-Art Research and Initiatives in Japan)
  • Article
  • Open Access
5 Citations
6,486 Views
12 Pages

The diagnosis of a child’s complex chronic illness may impact family relationships and cohesion. The Impact on Family Scale (IFS) is an instrument used to assess the parental perception of the effects of children’s chronic illness on fami...

(This article belongs to the Special Issue Health Behavior and Health Promotion in Children and Adolescents)
  • Article
  • Open Access
6 Citations
5,078 Views
16 Pages

10 March 2020

Commercially bottled birch saps (BSs) were analyzed for several nutrient (Ca, Cu, Fe, Mg, and Zn) and toxic (As, Cd, Ni, and Pb) elements using inductively coupled plasma optical emission spectrometry (ICP OES). The method was validated under the con...

(This article belongs to the Section Analytical Chemistry)
  • Article
  • Open Access
11 Citations
4,546 Views
18 Pages

Pilot Validation Study of Inertial Measurement Units and Markerless Methods for 3D Neck and Trunk Kinematics during a Simulated Surgery Task

  • Ce Zhang,
  • Christian Greve,
  • Gijsbertus Jacob Verkerke,
  • Charlotte Christina Roossien and ,
  • Han Houdijk and
  • Juha M. Hijmans
  • + 1 author+ 0 author

30 October 2022

Surgeons are at high risk for developing musculoskeletal symptoms (MSS), like neck and back pain. Quantitative analysis of 3D neck and trunk movements during surgery can help to develop preventive devices such as exoskeletons. Inertial Measurement Un...

(This article belongs to the Special Issue Wearable Sensors for Physical Activity and Healthcare Monitoring)
  • Article
  • Open Access
2 Citations
3,177 Views
10 Pages

Measurement of Social Strain in People with Dementia: A Preliminary Study of the Reliability and Validity of the Negative Relationship Quality Questionnaire in Indonesia

  • Amelia Nur Vidyanti,
  • Galenisa Falinda Santika Putri,
  • Aditya Rifqi Fauzi,
  • Rizqa Nafiati and ,
  • Astuti Prodjohardjono and
  • Christantie Effendy
  • + 1 author+ 0 author

15 September 2022

People with dementia (PWD) may exhibit symptoms that negatively affect their relationships with their families or friends which could cause social strain. The Negative Relationship Quality (NRQ) questionnaire can be used to measure social strain in P...

(This article belongs to the Section Geriatric Neurology)
  • Article
  • Open Access
3 Citations
3,273 Views
9 Pages

6 October 2021

Empirical validation and verification procedures require the sophisticated development of research methodology. Therefore, researchers and practitioners in human–machine interaction and the automotive domain have developed standardized test protocols...

of 2,424