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  • Review
  • Open Access
5 Citations
5,143 Views
24 Pages

Scanning the Horizon for Environmental Applications of Genetically Modified Viruses Reveals Challenges for Their Environmental Risk Assessment

  • Michael F. Eckerstorfer,
  • Marion Dolezel,
  • Marianne Miklau,
  • Anita Greiter,
  • Andreas Heissenberger and
  • Margret Engelhard

25 January 2024

The release of novel genetically modified (GM) virus applications into the environment for agricultural, veterinary, and nature-conservation purposes poses a number of significant challenges for risk assessors and regulatory authorities. Continuous e...

(This article belongs to the Special Issue Virus Engineering and Applications: 2nd Edition)
  • Article
  • Open Access
9 Citations
2,807 Views
17 Pages

7 May 2024

Soil heavy metal contamination poses a significant threat to both environmental health and ecological safety. To investigate the influencing factors, ecological hazards, and sources analysis of heavy metals in purple soil, 27 sets of soil samples wer...

(This article belongs to the Special Issue Heavy Metal and Rare Earth Element Pollution in Soil and Water: Sources, Geochemical Behaviors and Ecological Effects)
  • Article
  • Open Access
21 Citations
5,709 Views
23 Pages

Enhancing Weather Forecasting Integrating LSTM and GA

  • Rita Teixeira,
  • Adelaide Cerveira,
  • Eduardo J. Solteiro Pires and
  • José Baptista

1 July 2024

Several sectors, such as agriculture and renewable energy systems, rely heavily on weather variables that are characterized by intermittent patterns. Many studies use regression and deep learning methods for weather forecasting to deal with this vari...

(This article belongs to the Special Issue Feature Paper Collection in the Section ‘Energy Science and Technology’)
  • Article
  • Open Access
7 Citations
2,523 Views
19 Pages

30 October 2023

This article studies the morphological and physicochemical properties of soils in the natural habitat of dandelion kok-saghyz (Taraxacum kok-saghyz L.E. Rodin) (TKS)—a source of high-quality rubber. The purpose of the work is to study the natur...

(This article belongs to the Topic Advances in Industrial Crops Physioecology and Sustainable Cultivation)
  • Article
  • Open Access
41 Citations
7,164 Views
23 Pages

3 September 2018

The efficient scheduling of carrier aircraft support operations in the flight deck is important for battle performances. The supporting operations and maintenance processes involve multiple support resources, complex scheduling process, and multiple...

  • Article
  • Open Access
21 Citations
5,896 Views
17 Pages

Undisturbed Soil Pedon under Birch Forest: Characterization of Microbiome in Genetic Horizons

  • Natalia B. Naumova,
  • Ivan P. Belanov,
  • Tatiana Y. Alikina and
  • Marsel R. Kabilov

Vast areas of land in the forest-steppe of West Siberia are occupied by birch forests, the most common ecosystems there. However, currently, little is known about the microbiome composition in the underlying soil, especially along a sequence of soil...

(This article belongs to the Special Issue Role of Soil Organisms in Modification of their Environment, Nutrient Cycling and Soil Formation)
  • Article
  • Open Access
13 Citations
5,044 Views
13 Pages

Vehicle-to-Infrastructure-Based Traffic Signal Optimization for Isolated Intersection

  • Yingjun Qiao,
  • Tianchuang Meng,
  • Hongmao Qin,
  • Ziniu Hu and
  • Zhihua Zhong

13 April 2023

Traffic signal control is critical for traffic efficiency optimization but is usually constrained by traffic detection methods. The emerging V2I (Vehicle to Infrastructure) technology is capable of providing rich information for traffic detection, th...

  • Conference Report
  • Open Access
23 Citations
12,122 Views
20 Pages

Expert and Advocacy Group Consensus Findings on the Horizon of Public Health Genetic Testing

  • Stephen M. Modell,
  • Karen Greendale,
  • Toby Citrin and
  • Sharon L. R. Kardia

Description: Among the two leading causes of death in the United States, each responsible for one in every four deaths, heart disease costs Americans $300 billion, while cancer costs Americans $216 billion per year. They also rank among the top three...

(This article belongs to the Special Issue Implementation of Public Health Genomics)
  • Review
  • Open Access
30 Citations
9,600 Views
18 Pages

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic condition characterized by progressive extra-skeletal ossification leading to cumulative and severe disability. FOP has an extremely variable and episodic course and can be induced by trau...

(This article belongs to the Special Issue Rare Diseases: Molecular Mechanisms and Therapeutic Strategies)
  • Review
  • Open Access
32 Citations
12,143 Views
8 Pages

15 September 2015

The national effort to use genomic knowledge to save lives is gaining momentum, as illustrated by the inclusion of genomics in key public health initiatives, including Healthy People 2020, and the recent launch of the precision medicine initiative. T...

(This article belongs to the Special Issue Implementation of Public Health Genomics)
  • Article
  • Open Access
19 Citations
5,209 Views
15 Pages

Soil-Available Nutrients Associated with Soil Chemical and Aggregate Properties following Vegetation Restoration in Western Sichuan, China

  • Huan Cheng,
  • Mingxuan Che,
  • Wangyang Hu,
  • Qiang Wu,
  • Yilun Cheng,
  • Xu Hu,
  • Shichen Xiong,
  • Jiangkun Zheng and
  • Yuanbo Gong

30 January 2023

The status and drivers of soil-available nutrients in plant-recovered soils are not fully understood, limiting our ability to explore the role of soil-available nutrients in soil geochemical cycling and ecosystem sustainability. Here, we combined the...

(This article belongs to the Special Issue Effects of Disturbances on Forest Soil Biochemistry)
  • Article
  • Open Access
6 Citations
2,069 Views
22 Pages

30 July 2025

The Parnassos-Ghiona region constitutes the most significant bauxite-bearing province in Greece, with a well-documented history of research highlighting its geotectonic complexity and its importance for bauxite exploitation. Among the three principal...

(This article belongs to the Section Mineral Deposits)
  • Article
  • Open Access
2,364 Views
13 Pages

Since the outbreak of the Coronavirus Disease 2019 (COVID-19), the spread of the epidemic has been a major international public health issue. Hence, various forecasting models have been used to predict the infectious spread of the disease. In general...

(This article belongs to the Special Issue Recent Advances in Data Science and Information Technology)
  • Article
  • Open Access
11 Citations
5,168 Views
12 Pages

The Genetic Basis of Anthocyanin Acylation in North American Grapes (Vitis spp.)

  • Avinash Karn,
  • Luis Diaz-Garcia,
  • Noam Reshef,
  • Cheng Zou,
  • David C. Manns,
  • Lance Cadle-Davidson,
  • Anna Katharine Mansfield,
  • Bruce I. Reisch and
  • Gavin L. Sacks

9 December 2021

Hydroxycinnamylated anthocyanins (or simply ‘acylated anthocyanins’) increase color stability in grape products, such as wine. Several genes that are relevant for anthocyanin acylation in grapes have been previously described; however, co...

(This article belongs to the Section Plant Genetics and Genomics)
  • Article
  • Open Access
19 Citations
4,915 Views
17 Pages

Adaptation in time-triggered systems can be motivated by energy efficiency, fault recovery, and changing environmental conditions. Adaptation in time-triggered systems is achieved by preserving temporal predictability through metascheduling technique...

(This article belongs to the Section Computer Science & Engineering)
  • Article
  • Open Access
21 Citations
5,536 Views
14 Pages

Changes of Soil Organic Carbon after Wildfire in a Boreal Forest, Northeast CHINA

  • Chun-Lan Han,
  • Zhong-Xiu Sun,
  • Shuai Shao,
  • Qiu-Bing Wang,
  • Zamir Libohova and
  • Phillip Ray Owens

25 September 2021

Boreal forests with high carbon sequestration capacity play a crucial role in mitigating global climate change. Addressing dynamic changes of soil organic carbon (SOC) after wildfire helps in understanding carbon cycling. The objective of this study...

(This article belongs to the Special Issue Soil Sustainability in the Anthropocene)
  • Article
  • Open Access
40 Citations
8,531 Views
13 Pages

17 November 2017

The aim of the study was to present effects of soil properties, especially moisture, on the quantity and quality of soil organic matter. The investigation was performed in the Czarna Rózga Reserve in Central Poland. Forty circular test areas were loc...

(This article belongs to the Special Issue Carbon, Nitrogen and Phosphorus Cycling in Forest Soils)
  • Review
  • Open Access
8 Citations
7,488 Views
25 Pages

Background/Objectives: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by challenges in social communication, restricted interests, and repetitive behaviors. Recent studies highlight the crucial roles of neuroglial cel...

  • Feature Paper
  • Article
  • Open Access
4 Citations
5,001 Views
15 Pages

11 March 2019

This paper studies the optimal investment and consumption strategies in a two-asset model. A dynamic Value-at-Risk constraint is imposed to manage the wealth process. By using Value at Risk as the risk measure during the investment horizon, the decis...

(This article belongs to the Special Issue Loss Models: From Theory to Applications)
  • Review
  • Open Access
18 Citations
10,647 Views
21 Pages

Transforming Ocean Conservation: Applying the Genetic Rescue Toolkit

  • Ben J. Novak,
  • Devaughn Fraser and
  • Thomas H. Maloney

18 February 2020

Although oceans provide critical ecosystem services and support the most abundant populations on earth, the extent of damage impacting oceans and the diversity of strategies to protect them is disconcertingly, and disproportionately, understudied. Wh...

(This article belongs to the Section Technologies and Resources for Genetics)
  • Review
  • Open Access
21 Citations
6,273 Views
22 Pages

Intracranial Aneurysms and Genetics: An Extensive Overview of Genomic Variations, Underlying Molecular Dynamics, Inflammatory Indicators, and Forward-Looking Insights

  • Corneliu Toader,
  • Lucian Eva,
  • Bogdan-Gabriel Bratu,
  • Razvan-Adrian Covache-Busuioc,
  • Horia Petre Costin,
  • David-Ioan Dumitrascu,
  • Luca-Andrei Glavan,
  • Antonio Daniel Corlatescu and
  • Alexandru Vlad Ciurea

12 October 2023

This review initiates by outlining the clinical relevance of IA, underlining the pressing need to comprehend its foundational elements. We delve into the assorted risk factors tied to IA, spotlighting both environmental and genetic influences. Additi...

(This article belongs to the Special Issue Management of Cerebrovascular Disease and Its Complications: Advances and Challenges)
  • Article
  • Open Access
10 Citations
3,863 Views
23 Pages

Anatomical Structure and Phytochemical Composition of a Rare Species Fraxinus sogdiana Bunge (Oleaceae) Growing in Different Soils in Kazakhstan

  • Almagul Aldibekova,
  • Meruyert Kurmanbayeva,
  • Ahmet Aksoy,
  • Valeria Permitina,
  • Liliya Dimeyeva and
  • Nikolai Zverev

12 June 2023

Fraxinus sogdiana Bunge (family Oleaceae) is a rare, relict species, with a disjunctive distribution range. The species is listed in the Red Book of Kazakhstan. The aim of this study was to determine anatomical features and identify the phytochemical...

(This article belongs to the Section Plant Diversity)
  • Feature Paper
  • Article
  • Open Access
6 Citations
3,916 Views
24 Pages

3 December 2022

Although the phosphatase enzymes regulate phosphorus (P) turnover throughout the soil profile, at present, they are rarely studied and are less well understood in the deeper soil layers than in the surface horizons. Hence the changes in P-associated...

(This article belongs to the Special Issue Soil Enzymatic Activity and Physicochemical Properties in Agriculture System)
  • Review
  • Open Access
15 Citations
5,749 Views
13 Pages

Stroke and Etiopathogenesis: What Is Known?

  • Tiziana Ciarambino,
  • Pietro Crispino,
  • Erika Mastrolorenzo,
  • Antonello Viceconti and
  • Mauro Giordano

30 May 2022

Background: A substantial portion of stroke risk remains unexplained, and a contribution from genetic factors is supported by recent findings. In most cases, genetic risk factors contribute to stroke risk as part of a multifactorial predisposition. A...

(This article belongs to the Special Issue Genomics of Stroke)
  • Review
  • Open Access
47 Citations
10,087 Views
12 Pages

10 January 2018

Feline leukemia virus (FeLV) was the first feline retrovirus discovered, and is associated with multiple fatal disease syndromes in cats, including lymphoma. The original research conducted on FeLV employed classical virological techniques. As method...

(This article belongs to the Section Animal Viruses)
  • Review
  • Open Access
130 Citations
15,378 Views
20 Pages

Systemic lupus erythematosus (SLE) is a clinically and genetically heterogeneous autoimmune disease. The etiology of lupus and the contribution of genetic, environmental, infectious and hormonal factors to this phenotype have yet to be elucidated. Th...

(This article belongs to the Special Issue New Insights into Systemic Lupus Erythematosus: From Immunopathogenesis to Treatment Strategies)
  • Review
  • Open Access
20 Citations
6,132 Views
15 Pages

Precision Oncology Targets in Biliary Tract Cancer

  • Nicole Farha,
  • Danai Dima,
  • Fauzia Ullah and
  • Suneel Kamath

31 March 2023

Targeted therapies in biliary tract cancer (BTC) are emerging as options for patients not who do not respond to first-line treatment. Agents acting on tumor-specific oncogenes in BTC may target fibroblast growth factor receptor 2 (FGFR2), isocitrate...

(This article belongs to the Collection Oncology: State-of-the-Art Research in the USA)
  • Article
  • Open Access
11 Citations
6,869 Views
18 Pages

4 January 2017

The hybrid flow shop is a typical discrete manufacturing system. A novel method is proposed to solve the shop scheduling problem featured with uncertain processing times. The rolling horizon strategy is adopted to evaluate the difference between a pr...

(This article belongs to the Special Issue Modeling, Simulation, Operation and Control of Discrete Event Systems)
  • Review
  • Open Access
9 Citations
6,477 Views
38 Pages

Treatment of Chronic Lymphocytic Leukemia in the Personalized Medicine Era

  • María Del Mar Sánchez Suárez,
  • Alicia Martín Roldán,
  • Carolina Alarcón-Payer,
  • Miguel Ángel Rodríguez-Gil,
  • Jaime Eduardo Poquet-Jornet,
  • José Manuel Puerta Puerta and
  • Alberto Jiménez Morales

Chronic lymphocytic leukemia is a lymphoproliferative disorder marked by the expansion of monoclonal, mature CD5+CD23+ B cells in peripheral blood, secondary lymphoid tissues, and bone marrow. The disease exhibits significant heterogeneity, with nume...

(This article belongs to the Special Issue Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine)
  • Article
  • Open Access
7 Citations
3,102 Views
11 Pages

The virulence gene ToxA has been proposed to be horizontally transferred between three fungal wheat pathogens (Parastagonospora nodorum, Pyrenophora tritici-repentis, and Bipolaris sorokiniana) as part of a conserved ~14 kb ToxhAT transposon. Here, o...

(This article belongs to the Special Issue Fungal Biology and Interactions, 2nd Edition)
  • Review
  • Open Access
8 Citations
11,230 Views
42 Pages

Population Genetic Structure: Where, What, and Why?

  • Adomas Ragauskas,
  • Evelina Maziliauskaitė,
  • Petras Prakas and
  • Dalius Butkauskas

20 August 2025

Biodiversity is crucial for humankind. It encompasses three main levels: ecosystem, species, and intraspecific genetic diversity. Species consist of populations that exhibit deoxyribonucleic acid (DNA) variability, which is a key component of intrasp...

(This article belongs to the Section Biodiversity Conservation)
  • Article
  • Open Access
8 Citations
5,247 Views
23 Pages

Authigenic Green Mica in Interflow Horizons within Late Cretaceous Deccan Volcanic Province, India and Its Genetic Implications

  • Pragya Singh,
  • Santanu Banerjee,
  • Kanchan Pande,
  • Satadru Bhattacharya,
  • Subham Sarkar and
  • Emilia Le Pera

3 February 2022

Green authigenic mica, i.e., celadonite, is commonly associated with submarine alteration of basic igneous rock. However, very few studies have reported the formation of celadonite under nonmarine conditions. An integrated study involving field inves...

(This article belongs to the Special Issue Iron Biogeochemical Cycle: Relationship with Global and Regional Earth Processes, and Ore Deposits Formation)
  • Article
  • Open Access
20 Citations
8,980 Views
24 Pages

16 February 2015

According to the topological structure of wind-storage-load complementation microgrids, this paper proposes a method for energy coordinative optimization which focuses on improvement of the economic benefits of microgrids in the prediction framework....

(This article belongs to the Special Issue Microgrids)
  • Article
  • Open Access
5 Citations
1,769 Views
20 Pages

22 July 2025

To address the challenges of model uncertainty, strong nonlinearities, and controller tuning in high-precision trajectory tracking for hydraulic servo systems, this paper proposes a hierarchical GA-PID-MPC fusion strategy. The architecture integrates...

(This article belongs to the Section Control Systems)
  • Review
  • Open Access
66 Citations
14,389 Views
15 Pages

Ischemic Stroke Genetics: What Is New and How to Apply It in Clinical Practice?

  • Aleksandra Ekkert,
  • Aleksandra Šliachtenko,
  • Julija Grigaitė,
  • Birutė Burnytė,
  • Algirdas Utkus and
  • Dalius Jatužis

24 December 2021

The etiology of ischemic stroke is multifactorial. Although receiving less emphasis, genetic causes make a significant contribution to ischemic stroke genesis, especially in early-onset stroke. Several stroke classification systems based on genetic i...

(This article belongs to the Special Issue Gene Expression and Chromatin Modification in the Brain)
  • Article
  • Open Access
8 Citations
3,182 Views
19 Pages

Methodology and Results of Detailed 3D Seismic Exploration in the Zhezkazgan Ore District

  • Arman Sirazhev,
  • Sara Istekova,
  • Dina Tolybaeva,
  • Kuanysh Togizov and
  • Raushan Temirkhanova

9 January 2025

This article presents the results obtained from a high-resolution wide-azimuthal 3D seismic reflection method used for the prediction and detailed exploration of complex ore targets in the Zhezkazgan ore district of Central Kazakhstan. We demonstrate...

  • Article
  • Open Access
1 Citations
2,674 Views
18 Pages

5 September 2025

Product-service systems contribute to sustainable development through innovative service integration and novel customer value creation. However, the competitive advantage of sustainable product lifecycle service delivery hinges critically on the oper...

(This article belongs to the Section Sustainable Products and Services)
  • Article
  • Open Access
6 Citations
2,614 Views
21 Pages

14 December 2023

Nowadays, multi-access edge computing (MEC) has been widely recognized as a promising technology that can support a wide range of new applications for the Internet of Things (IoT). In dynamic MEC networks, the heterogeneous computation capacities of...

(This article belongs to the Special Issue Asymmetrical Network Control for Complex Dynamic Services)
  • Review
  • Open Access
14 Citations
5,933 Views
18 Pages

The most famous yeast of all, Saccharomyces cerevisiae, has been used by humankind for at least 8000 years, to produce bread, beer and wine, even without knowing about its existence. Only in the last century we have been fully aware of the amazing po...

(This article belongs to the Special Issue From Yeast to Biotechnology)
  • Review
  • Open Access
115 Citations
28,987 Views
20 Pages

Important Hormones Regulating Lipid Metabolism

  • Dengke Zhang,
  • Yanghui Wei,
  • Qingnan Huang,
  • Yong Chen,
  • Kai Zeng,
  • Weiqin Yang,
  • Juan Chen and
  • Jiawei Chen

19 October 2022

There is a wide variety of kinds of lipids, and complex structures which determine the diversity and complexity of their functions. With the basic characteristic of water insolubility, lipid molecules are independent of the genetic information compos...

(This article belongs to the Section Natural Products Chemistry)
  • Feature Paper
  • Article
  • Open Access
11 Citations
4,157 Views
16 Pages

A MPC Strategy for the Optimal Management of Microgrids Based on Evolutionary Optimization

  • Álvaro Rodríguez del Nozal,
  • Daniel Gutiérrez Reina,
  • Lázaro Alvarado-Barrios,
  • Alejandro Tapia and
  • Juan Manuel Escaño

19 November 2019

In this paper, a novel model predictive control strategy, with a 24-h prediction horizon, is proposed to reduce the operational cost of microgrids. To overcome the complexity of the optimization problems arising from the operation of the microgrid at...

(This article belongs to the Section Power Electronics)
  • Article
  • Open Access
3 Citations
2,686 Views
19 Pages

Soils in Understanding Land Surface Construction: An Example from Campania Plain, Southern Italy

  • Antonella Ermice,
  • Rossana Marzaioli,
  • Marco Vigliotti,
  • Pierferdinando Lamberti and
  • Daniela Ruberti

19 September 2024

The contribution of sediment transport and accumulation to soil formation was investigated in an area characterized by continental sedimentary activity since the Late Pleistocene. The area was the north-eastern portion of the large Quaternary graben...

  • Article
  • Open Access
49 Citations
5,859 Views
28 Pages

Multiple Site Intraday Solar Irradiance Forecasting by Machine Learning Algorithms: MGGP and MLP Neural Networks

  • Gabriel Mendonça de Paiva,
  • Sergio Pires Pimentel,
  • Bernardo Pinheiro Alvarenga,
  • Enes Gonçalves Marra,
  • Marco Mussetta and
  • Sonia Leva

11 June 2020

The forecasting of solar irradiance in photovoltaic power generation is an important tool for the integration of intermittent renewable energy sources (RES) in electrical utility grids. This study evaluates two machine learning (ML) algorithms for in...

(This article belongs to the Special Issue Solar and Wind Power and Energy Forecasting)
  • Article
  • Open Access
4 Citations
4,984 Views
17 Pages

Recent History, Use and Forgetfulness of the Cypress Forest of Fontegreca (Southern Italy)

  • Alessia D’Auria,
  • Simona Vingiani,
  • Fabio Marzaioli,
  • Maurizio Teobaldelli and
  • Gaetano Di Pasquale

2 December 2020

The cypress (Cupressus sempervirens) is characterized by a very ancient history linked to the wide employment for the technological properties of its wood and for its symbolic value. Although this tree was often considered as a species introduced in...

(This article belongs to the Section Plant Diversity)
  • Article
  • Open Access
16 Citations
5,821 Views
27 Pages

8 March 2018

Fuel preparation is the control bottleneck in coal-fired power plants due to the unmeasurable nature or inaccurate measurement of key controlled variables. This paper proposes an inferential multi-model predictive control scheme based on moving horiz...

(This article belongs to the Special Issue Control and Nonlinear Dynamics on Energy Conversion Systems)
  • Article
  • Open Access
7 Citations
2,433 Views
12 Pages

7 December 2023

For heterogeneous reservoirs that develop due to water flooding, the increased degree of flooding will cause unbalanced displacement, and there are large areas of residual oil enrichment in the reservoir. In this paper, a genetic coding method for oi...

  • Review
  • Open Access
6 Citations
2,722 Views
19 Pages

In Vitro Culture of Avian Primordial Germ Cells: Established Methods and Future Directions

  • Jehan Nayga,
  • Elen Gócza,
  • Eszter Várkonyi and
  • Bence Lázár

14 November 2025

Primordial germ cells (PGCs) are the unipotent precursors of sperm and ova, responsible for transmitting hereditary information across generations. Their ability to be isolated and cultured in vitro has opened new horizons for avian biotechnology, sp...

(This article belongs to the Section Biotechnology)
  • Article
  • Open Access
10 Citations
3,701 Views
11 Pages

Cost-Effectiveness of Screening Algorithms for Familial Hypercholesterolaemia in Primary Care

  • Matthew Jones,
  • Ralph K. Akyea,
  • Katherine Payne,
  • Steve E. Humphries,
  • Hasidah Abdul-Hamid,
  • Stephen Weng and
  • Nadeem Qureshi

22 February 2022

Although familial hypercholesterolemia (FH) screening within primary care is considered cost-effective, which screening approach is cost-effective has not been established. This study determines the cost-effectiveness of six case-finding strategies f...

  • Article
  • Open Access
3,075 Views
14 Pages

13 February 2024

This paper investigates a dynamic liability-driven investment policy for defined-benefit (DB) plans by incorporating the loss aversion of a sponsor, who is assumed to be more sensitive to underfunding than overfunding. Through the lens of prospect th...

(This article belongs to the Special Issue Life Insurance and Pensions: Latest Advances and Prospects)

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