82,434 Results Found

Background/Objectives: Cancer is a leading cause of death. However, recently developed immunotherapies have shown significant promise to improve cancer treatment outcomes and survival rates. Pembrolizumab, a cancer immunotherapy drug, enables a stron...

Specialized cancer treatments have the potential to exploit glutamine dependence to increase patient survival rates. Glutamine diagnostics capable of tracking a patient’s response to treatment would enable a personalized treatment dosage to opt...

Glutamine is an essential biomolecule that plays a pivotal role in many diseases, such as cancer, where it can serve as fuel for rapid proliferation. Treatments for these diseases can be monitored and optimized through the detection of glutamine, tho...

Diagnostic blood tests can guide the administration of healthcare to save and improve lives. Most clinical biosensing blood tests require a trained technician and specialized equipment to process samples and interpret results, which greatly limits te...

Thyroid receptor signaling controls major physiological processes and disrupted signaling can cause severe disorders that negatively impact human life. Consequently, methods to detect thyroid receptor ligands are of great toxicologic and pharmacologi...

Binary cube-free language and ternary square-free language are two “canonical” representatives of a wide class of languages defined by avoidance properties. Each of these two languages can be viewed as an infinite binary tree reflecting the prefix or...

Damage can be detected by vibration responses of a structure. Damage changes the modal properties such as natural frequencies, mode shapes, and damping ratios. Natural frequency is one of the most frequently used damage indicators. In this paper, the...

Known and new results on free Boolean topological groups are collected. An account of the properties that these groups share with free or free Abelian topological groups and properties specific to free Boolean groups is given. Special emphasis is pla...

Cell-free systems are a widely used research tool in systems and synthetic biology and a promising platform for manufacturing of proteins and chemicals. In the past, cell-free biology was primarily used to better understand fundamental biochemical pr...

The investigation of free additive convolution is a key concept in free probability theory, offering a framework for studying the sum of freely independent random variables. This paper uses free additive convolution and measure dilations to investiga...

High free sugar intake can lead to increased dental caries, obesity, and other health risks among adolescents. Studies have shown that family factors, especially parents, are one of the primary factors influencing adolescents’ sugar intake. Thi...

In this study, particle loading, polyfluorinated alkyl silanes (PFAS or FAS) content, superhydrophobicity, and crack formation for nanocomposite coatings created by the spray coating process were investigated. The formulations comprised hydrophobic s...

The concept of r-free convolution (which is represented by $\begin{array}{|c|}\hline r\\ \hline\end{array}$) was introduced for $0\le r\le 1$. It is equal to the Boolean additive convolution ⊎ if $r=0$ and reduced to the free additive convolution ⊞ when $r=1$. This paper presents certain fe...

Beam models are widely applied in civil engineering, transport, and industry because the beams are basic structural elements. When dealing with the high-order modes of beam in the context of applying the modal analysis method, the numerical instabili...

Simplifying the design of lead-free perovskite solar cells (PSCs) has drawn a lot of interest due to their low manufacturing cost and relative non-toxic nature. Focus has been placed mostly on reducing the toxic lead element and eliminating the requi...

Minimal free resolutions of a finitely generated module over a polynomial ring $S=k\left[\mathbf{x}\right]$, with variables $\mathbf{x}=\{x_1,\dots ,x_n\}$ and a field k have been extensively studied. Almost all the results in the literature about minimal free resolutions give their B...

Poultry welfare has been extensively studied; however, there is a lack of rigorous scientific knowledge relating to the different aspects of welfare factors and how this may contribute to the production quantity and product quality as well as the wel...

This study analyzed the statement “diversification is a free lunch”. We empirically showed that diversification is only a free lunch under uncertainty or ignorance, confirming Warren Buffett’s “diversification is protection ag...

The persistent free radical content in petroleum is of the order 10¹⁸ spins/g (1 μmol/g), with higher and lower values found depending on origin and in different distillation fractions. The field of persistent free radicals in petroleum was review...

The modelling of complex free surface flows over weirs and in the vicinity of bridge piers is presented in a numerical model emulating open channel flow based on the Reynolds Averaged Navier-Stokes (RANS) equations. The importance of handling the tur...

With the development of technology, the number of free-form structures—as well as their value—is increasing. In order to construct such free-form structures, a number of studies are being conducted on free-form molds from multifaceted per...

This paper explores the stochastic collocation technique, applied on a monotonic spline, as an arbitrage-free and model-free interpolation of implied volatilities. We explore various spline formulations, including B-spline representations. We explain...

Predictive control offers many advantages such as simple design and a systematic way to handle constraints. Model predictive control (MPC) belongs to predictive control, which uses a model of the system for predictions used in predictive control. A m...

In Philadelphia chromosome-positive B-cell (Ph+) acute lymphoblastic leukemia (LLA), growing evidence has accumulated regarding the efficacy of low-intensity and chemo-free regimens. Our objective was to analyze all recent trials evaluating these tre...

A portable incoherent digital holography system without a polarization filter or a refractive lens was developed. Phase-shifted self-interference incoherent holograms of light diffracted from an object were generated without attenuation due to a pola...

The metabolic network’s primary sources of free fatty acids (FFAs) are long- and medium-chain fatty acids of triglyceride origin and short-chain fatty acids produced by intestinal microorganisms through dietary fibre fermentation. Recent studie...

The purpose of this study is to investigate the effect of free nitrous acid (FNA) and free ammonia (FA) on the anoxic phosphorus uptake rate (PUR) of polyphosphate-accumulating organisms (PAOs) via the utilization of nitrite. With this goal, upon dev...

A mobile loop changes its conformation from “open” (free enzyme) to “closed” upon ligand binding. The difference in the Helmholtz free energy, ΔF_loop between these states sheds light on the mechanism of binding. With our “hypothetical scanning molecu...

Peer-to-peer (P2P) architecture is increasingly gaining attention as a potential solution for the scalability problem facing the Internet of Things (IoT). It can be adopted for the fog computing layer to sustain the massive flow of data from constrai...

Cell-free systems are a rapidly expanding platform technology with an important role in the engineering of biological systems. The key advantages that drive their broad adoption are increased efficiency, versatility, and low cost compared to in vivo...

Approximately one-third of long rivers remain free-flowing, and rivers face a range of ongoing and future threats. In response, there is a heightened call for actions to reverse the freshwater biodiversity crisis, including through formal global targ...

Head and neck free-flap microvascular surgeries are complex and resource-intensive procedures where proper conduct of anaesthesia plays a crucial role in the outcome. Flap failure and postoperative complications can be attributed to multiple factors,...

Starch is widely used as an ingredient and significantly contributes to texture, appearance, and overall acceptability of cereal based foods, playing an important role due to its ability to form a matrix, entrapping air bubbles. A detailed characteri...

Cell-free protein synthesis (CFPS) is a platform technology that provides new opportunities for protein expression, metabolic engineering, therapeutic development, education, and more. The advantages of CFPS over in vivo protein expression include it...

Maximizing the amount of work harvested from an environment is important for a wide variety of biological and technological processes, from energy-harvesting processes such as photosynthesis to energy storage systems such as fuels and batteries. Here...

For positive integers s and t, the Ramsey number $R(s,t)$ is the smallest positive integer n such that every graph of order n contains either a clique of order s or an independent set of order t. The triangle-free process begins with an em...

The aim of this study is to investigate consumer attitudes toward the quality and availability of gluten-free products. For this purpose, quantitative research was conducted using a questionnaire completed by 107 respondents who consumed gluten-free...

A binary grammar is a relational grammar with two nonterminal alphabets, two terminal alphabets, a set of pairs of productions and the pair of the initial nonterminals that generates the binary relation, i.e., the set of pairs of strings over the ter...

In this paper, we discuss some of the key properties of sum-free subsets of abelian groups. Our discussion has been designed with a broader readership in mind and is hence not overly technical. We consider answers to questions like the following: How...

We show that a class of downwardly skip-free processes can be regarded as the Siegmund dual of upwardly skip-free processes, which have been extensively studied in the literature. For such downwardly skip-free processes, using the duality method and...

Monetary policy and central banks faced significant challenges in recent decades, like the Great Recession and the 2008–2009 financial crisis, and the Global Inflation Surge of 2021–2022. The introduction of blockchain technology triggere...

Morus alba is an important medicinal plant that is used to treat human diseases. The leaf, branch, and root of Morus can be applied as antidiabetic, antioxidant, and anti-inflammatory medicines, respectively. To explore the molecular mechanisms under...

Background: Circulating miRNAs have been identified as potential biomarkers for the early diagnosis and monitoring of cancers. However, limitations of polymerase chain reaction (PCR)-based methods are currently delaying the transition of miRNA resear...

Let ${\mathcal{K}}_{+}\left({\mu }_i\right)=\{Q_{s_i}^{{\mu }_i},s_i\in (m_0^{{\mu }_i},m_{+}^{{\mu }_i})\}$, $i=1,2$, be two CSK families generated by the nondegenerate probability measures ${\mu }_1$ and ${\mu }_2$ with support bounded from above. Define the set of measures $\mathcal{L}={\mathcal{K}}_{+}\left({\mu }_1\right)•{\mathcal{K}}_{+}\left({\mu }_2\right)=\{Q_{s_1}^{{\mu }_1}•Q_{}^{}$...

Free sugars (FS) are associated with a higher risk of dental decay in children and an increased risk of weight gain, overweight and obesity and type 2 diabetes. For this reason, Canada’s Food Guide recommends limiting foods and beverages that contrib...

The study of the stability of measure families under measure transformations, as well as the accompanying limit theorems, is motivated by both fundamental and applied probability theory and dynamical systems. Stability analysis tries to uncover invar...

Gluten-free (GF) product labeling is one of the most important determinants of food product choices by patients with celiac disease, due to the need for following a GF diet. The aim of this study was to assess the role of front-of-package GF product...

In the growing context of sustainable chemistry, one of the challenges of organic chemists is to develop efficient and environmentally friendly methods for the synthesis of high-added-value products. Heterogeneous photocatalytic transformations have...

Since the discovery in 1922 of 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydrazyl stable free radical (DPPH^·), the chemistry of such open-shell compounds has developed continuously, allowing for both theoretical and practical advances in the free radical...

In this study, based on previous fundamental research on weldability, we ultimately aim to propose a filler metal that enables hot crack-free repair welding of 247LC superalloy while minimizing compositional modification. First, we investigated the l...