Leydig cells (LCs) are the predominant cells of androgen production, which plays key roles in spermatogenesis and maintaining male secondary sexual characteristics. Abnormal development of LCs affects androgen levels in vivo, affects fertility and ma...
The diagnosis and classification of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is essential to improve the prognosis of systemic sclerosis (SSc) patients. The risk-stratification of disease severity and follow-up requires a mul...
miRNA is a small non-coding RNA, which plays an important role in diverse biological processes. In the present study, we explore the effect of ssc-miR-451 on porcine adipose development and meat quality. We observed that ssc-miR-451 was downregulated...
Synthetic aperture radar (SAR), as a wideband radar system, is easily contaminated by radio frequency interference (RFI), which affects the imaging quality of SAR. The subband spectral cancellation (SSC) method and its modifications utilize the SAR s...
Long-chain non-coding RNAs (lncRNAs) play important regulatory roles in the growth and development of skeletal muscle, but systematic identification and functional studies of lncRNAs related to porcine skeletal muscle development remain limited. Base...
Background and Objectives: Chronic lung diseases act as multi-organ conditions in which systemic inflammation, vascular dysfunction, and fibrosis intersect. The pulmo-renal continuum—functional crosstalk between lungs and kidneys—remains...
Background: Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular and immunity alterations and skin/internal organ fibrosis. Aberrant levels of plasma CXCL4, CXCL4–RNA/DNA complexes, type I IFN (IFN-I) and anti-CXCL4 antib...
Background: Interstitial lung disease (ILD) is a frequent complication of systemic sclerosis (SSc), and its early detection and treatment may prevent deterioration of lung function. Different vendors have recently made larger image matrices available...
The Tibetan pig is an endemic economic animal in the plateau region of China, and has a unique adaptation mechanism to the plateau hypoxic environment. Research into microRNAs (miRNAs) involved in the mechanism underlying hypoxia adaptation of Tibeta...
Systemic scleroderma (SSc) is an autoimmune disease characterized by excessive collagen production and progressive fibrosis. As the disease advances, vascular injury leads to fibrosis of the skin and internal organs, among which interstitial lung dis...
In digital soil mapping, machine learning models have been widely applied. However, the accuracy of machine learning models can be limited by the use of a single model and a small number of soil samples. This study introduces a novel method, semi-sup...
Near-infrared hyperspectral imaging (NIR-HSI) is widely used as a non-destructive technique for evaluating internal fruit quality; however, reliable pixel-wise visualization remains challenging due to geometry-induced spectral distortions and the lac...
Inflammatory diseases of the intestinal tract in piglets severely impair the economic performance of pig farms. Pig milk exosomes can encapsulate miRNAs which can then enter the piglet intestine to play an immunomodulatory role. Previously, we compar...
Seneca Valley virus (SVV), a member of the Picornaviridae family, is an oncolytic RNA virus that can cause idiopathic vesicular disease and increase mortality in newborn piglets. Although research on the pathogenic characteristics, epidemiology, path...
Glaesserella parasuis (G. parasuis), a common pathogenic bacterium in the porcine respiratory tract, can cause porcine polyserositis, arthritis, and meningitis. Alveolar macrophages are the first line of defense in the pulmonary innate immunity, and...
In the efforts towards germplasm innovation of livestock and poultry, strategies to improve meat quality have faced some increasingly challenging and dynamic concerns. Intramuscular fat (IMF) content and backfat thickness are two important traits con...
Although spermatogonial stem cells (SSC) constitute primary candidates for in vitro germ cell (GC) derivation, they are scarce and difficult to maintain in an undifferentiated state. Alternatively, mesenchymal stem cells (MSC) are also candidates for...
Piglet diarrhea caused by Clostridium perfringens (C. perfringens) type C (CpC) seriously endangers the development of the pig production industry. C. perfringens beta2 (CPB2) toxin is a virulent toxin produced by CpC. Long non-coding RNAs (lncRNAs)...
Colorectal cancer (CRC) is heterogeneous and deadly, and the exact cause of the disease is unknown. Recent progress indicated that CRC is not a single disease, but a group of diseases with significant heterogeneity. Three previous CRC subtyping syste...
A detailed analysis and validation of the DC-DC boost converter based on the three-state switching cell (3SSC) type-A are presented in this paper. The study of this topology is justified by the small amount of research that employs 3SSC-A and the adv...
Systemic sclerosis (SSc) is characterized by skin/internal organ fibrosis, vasculopathy and autoimmunity. Chemokine (C-X-C motif) ligand 4 (CXCL4) is an SSc biomarker, predicting unfavorable prognosis and lung fibrosis. CXCL4 binds DNA/RNA and favors...
This paper proposes two non-isolated step-down DC–DC converters based on the type-A three-state switching cell (3SSC-A), resulting in an alternative to the buck and buck-boost classical converters, respectively. The proposed topologies are part...
This study explores the development prospects of tourism in predominantly industrial small-sized cities (SSCs), focusing on the integration of tourism into urban planning and sustainable practices. Using structural equation modeling (SEM) to analyze...
Systemic sclerosis (SSc) is a connective tissue disease of unknown etiology. SSc causes damage to the skin and various organs including the lungs, heart, and digestive tract, but the extent of the damage varies from patient to patient. The pathology...
Systemic sclerosis (SSc) is a connective tissue disorder that results in fibrosis of the skin and visceral organs. SSc-associated pulmonary fibrosis (SSc-PF) is the leading cause of death amongst SSc patients. Racial disparity is noted in SSc as Afri...
Software-defined networking (SDN) and network function virtualization (NFV) make a network programmable, resulting in a more flexible and agile network. An important and promising application for these two technologies is network security, where they...
Embryo implantation, the pivotal stage of gestation, is fundamentally dependent on synchronous embryonic development and uterine receptivity. In the early gestation period, the uterus and conceptus secrete growth factors, cytokines, and hormones to p...
In this study, 22 strains of exopolysaccharides-producing lactic acid bacteria were isolated from silage, and the strain SSC–12 with the highest exopolysaccharide (EPS) production was used as the test strain. The SSC–12 was identified as...
We introduce <tt>ssc-cdi</tt>, an open-source software package from the Sirius Scientific Computing family, designed for memory-efficient, single-node multi-GPU ptychography reconstruction. <tt>ssc-cdi</tt> offers a range of r...
Background: to compare three existing screening algorithms of pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) with the results of a multidisciplinary team (MDT) meeting from a tertiary center. Methods: we conducted a monocentric lon...
Obesity contributes to a chronic proinflammatory state, which is a known risk factor to develop immune-mediated diseases. However, its role in systemic sclerosis (SSc) remains to be elucidated. Therefore, we conducted a two-sample mendelian randomiza...
Soluble solids content (SSC) measurements are crucial for managing longan production and post-harvest handling. However, most traditional SSC detection methods are destructive, cumbersome, and unsuitable for field applications. This study proposes a...
Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is a leading cause of morbidity and mortality in patients with systemic sclerosis. High-resolution computed tomography (HRCT) provides anatomical detail but cannot directly assess dise...
Systemic sclerosis (SSc) is a rare autoimmune disease whose molecular mechanisms are not yet fully understood. There is no definitive cure, and the main causes of death are pulmonary fibrosis and pulmonary arterial hypertension. Here, we focus on the...
Background: Systemic sclerosis (SSc) is characterized by endothelial dysfunction leading to progressive vascular injury and fibrosis. While microvascular involvement is well established as an early disease feature, macrovascular disease has been hist...
The near-infrared (NIR) spectral responses under different tissue states are important for nondestructive soluble solids content (SSC) assessment of thick-peeled citrus, but the effects of peel removal and progressive tissue exposure remain unclear....
Objective: To investigate in an unselected, systemic sclerosis (SSc) cohort if baseline laser speckle contrast analysis (LASCA) peripheral blood perfusion (PBP) measurements differ between ‘early’ SSc (without skin involvement, or ‘...
This study investigates the time-dependent compressive behavior of seawater sea-sand concrete (SSC) and establishes intelligent prediction models for its evaluation. SSC samples with three strength grades (C30, C40, and C60) were fabricated and teste...
A medium-carbon Cr–Mo–V martensitic steel was thermally processed by quenching (Q) at 890 °C and tempering (T) at increasing temperatures from 650 °C to 720 °C and the effect of tempering temperature, Tt, on sulfide stress cracking (SSC) behaviors wa...
Secreted Frizzled Receptor Protein 4 (SFRP4) has been shown to be increased in Scleroderma (SSc). To determine its role in immune-driven fibrosis, we analysed SSc and sclerotic Chronic Graft Versus Host Disease (sclGVHD) biosamples; skin biopsies (n...
Conventional remote sensing faces challenges in regions characterized by complex terrain, frequent cloud and fog cover, image scarcity, and mixed pixels. This study develops an integrated framework that sequentially combines spatiotemporal fusion, wa...
Systemic sclerosis (SSc) is characterized by a complex interplay of vascular damage, inflammation, and fibrosis, affecting the skin and internal organs. Plasminogen activator inhibitor-1 (PAI-1), a protein encoded by the SERPINE1 gene, is a potential...
Imaging plays a pivotal role in systemic sclerosis for both diagnosis management of pulmonary complications, and high-resolution computed tomography (HRCT) is the most sensitive technique for the evaluation of systemic sclerosis-associated interstiti...
The use of a portable near-infrared (NIR) spectrometer for detecting sea buckthorn juice SSC has not been explored. In this study, spectral data of 180 juice samples were collected using a portable NIR spectrometer. An SSC prediction model based on a...
Systemic sclerosis (SSc) is a clinically heterogeneous disorder of the connective tissue characterized by vascular alterations, immune/inflammatory manifestations, and organ fibrosis. SSc pathogenesis is complex and still poorly understood. Therefore...
Systemic sclerosis (SSc) is a complex autoimmune inflammatory disorder with multiple organ involvement. Skin changes present the hallmark of SSc and coincide with poor prognosis. Interstitial lung diseases (ILD) are the most widely reported complicat...
The diurnal variation of the suspended sediment concentration (SSC) in Hangzhou Bay, China has been investigated using remotely-sensed SSC derived from the Geostationary Ocean Color Imager (GOCI) in combination with a coupled hydrodynamic-ecological...
Background/Objectives: Predictors of ischemic vascular complications (IVCs)—including coronary artery disease (CAD), ischemic stroke, and digital gangrene—in patients with early SSc remain insufficiently defined. Therefore, we aim to dete...
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