Next Article in Journal
Automated COVID-19 and Heart Failure Detection Using DNA Pattern Technique with Cough Sounds
Next Article in Special Issue
Clinical Relevance of the Serial Measurement of Krebs von den Lungen-6 Levels in Patients with Systemic Sclerosis-Associated Interstitial Lung Disease
Previous Article in Journal
Platelet Activation and Inflammation in Patients with Papillary Thyroid Cancer
Previous Article in Special Issue
A Machine Learning Application to Predict Early Lung Involvement in Scleroderma: A Feasibility Evaluation
Review

High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients

1
Department of Pulmonology, University Hospital of Cattinara, 34149 Trieste, Italy
2
Department of Radiology, Cattinara Hospital, University of Trieste, 34149 Trieste, Italy
3
AOU City of Health and Science of Turin, Department of Science of Public Health and Pediatrics, University of Torino, 10124 Torino, Italy
*
Author to whom correspondence should be addressed.
Barbara Ruaro and Elisa Baratella equally contributed to this study and are shared first authors.
Academic Editor: Philippe A. Grenier
Diagnostics 2021, 11(11), 1960; https://doi.org/10.3390/diagnostics11111960
Received: 1 September 2021 / Revised: 12 October 2021 / Accepted: 13 October 2021 / Published: 22 October 2021
(This article belongs to the Special Issue Advances in Identification and Management of Systemic Sclerosis)
The diagnosis and classification of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is essential to improve the prognosis of systemic sclerosis (SSc) patients. The risk-stratification of disease severity and follow-up requires a multidisciplinary approach, integrating high-resolution computed tomography (HRTC) of the lung, pulmonary function tests (PFT), along with clinical and symptomatic evaluations. The use of HRCT in detecting SSc-ILD is not so much based on a definitive validation, but rather reflects the widespread clinician recognition of dissatisfaction with other modalities. However, due to the heterogeneity of SSc-ILD and the potential absence of symptoms in early or mild disease, it is prudent to consider as many parameters as possible in the assessment and monitoring of newly diagnosed patients. An early diagnosis meets the primary goal, i.e., the prevention of disease progression. The current first line treatment regimens are mainly centered on immunosuppressive therapy. This review assesses the role HRCT plays in optimizing care and improving clinical outcomes in SSc-ILD patients. View Full-Text
Keywords: systemic sclerosis-associated interstitial lung disease (SSc-ILD); interstitial lung disease (ILD); systemic sclerosis (SSc); high-resolution computed tomography (HRTC); pulmonary function tests (PFT); usual interstitial pneumonia (UIP) systemic sclerosis-associated interstitial lung disease (SSc-ILD); interstitial lung disease (ILD); systemic sclerosis (SSc); high-resolution computed tomography (HRTC); pulmonary function tests (PFT); usual interstitial pneumonia (UIP)
Show Figures

Figure 1

MDPI and ACS Style

Ruaro, B.; Baratella, E.; Confalonieri, P.; Wade, B.; Marrocchio, C.; Geri, P.; Busca, A.; Pozzan, R.; Andrisano, A.G.; Cova, M.A.; Confalonieri, M.; Salton, F. High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients. Diagnostics 2021, 11, 1960. https://doi.org/10.3390/diagnostics11111960

AMA Style

Ruaro B, Baratella E, Confalonieri P, Wade B, Marrocchio C, Geri P, Busca A, Pozzan R, Andrisano AG, Cova MA, Confalonieri M, Salton F. High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients. Diagnostics. 2021; 11(11):1960. https://doi.org/10.3390/diagnostics11111960

Chicago/Turabian Style

Ruaro, Barbara, Elisa Baratella, Paola Confalonieri, Barbara Wade, Cristina Marrocchio, Pietro Geri, Annalisa Busca, Riccardo Pozzan, Alessia G. Andrisano, Maria A. Cova, Marco Confalonieri, and Francesco Salton. 2021. "High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients" Diagnostics 11, no. 11: 1960. https://doi.org/10.3390/diagnostics11111960

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop