Immunology & Rheumatology
A section of Journal of Clinical Medicine (ISSN 2077-0383).
Section Information
Systemic inflammatory and autoimmune disorders encompass a large and heterogeneous group of diseases, falling under the domain of rheumatology and immunology.
A combination of genetic, immune, and environmental factors has been suggested to be involved in the pathogenesis of these disorders, primarily inducing a loss of immune self-tolerance. Alternatively, dysfunction within the inflammatory cascade may promote and perpetuate a systemic inflammatory disorder.
This section aims to integrate both immunological and rheumatological perspectives, highlighting the pathogenesis, diagnosis, and treatment of diseases rooted in immune system dysfunction. These include a spectrum of autoimmune diseases, systemic inflammatory disorders, vasculitides, and connective tissue diseases, such as rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome, and ankylosing spondylitis.
Both innate and adaptive immunity are central to understanding these conditions. Innate immunity provides a rapid but nonspecific defense, while adaptive immunity offers targeted responses and immunological memory. Dysregulation in either arm can lead to a wide range of diseases that are clinically managed by immunologists and rheumatologists alike.
We welcome original research, reviews, and clinical studies exploring the immune mechanisms of rheumatologic diseases; emerging clinical aspects of systemic autoimmune disorders; novel therapies, including biologics and targeted synthetic antirheumatic drugs; rheumatic complications arising from immune checkpoint inhibitors; and topics such as immune-related adverse events, immunosuppressive and immunomodulatory therapies, transplantation immunology, and emerging biomarkers.
By bridging immunology and rheumatology, this section encourages interdisciplinary insights and aims to support innovation in diagnostics and patient care.
Subject Areas
- Rheumatoid arthritis and spondyloarthropathies;
- Gout and crystal-induced arthritis;
- Systemic lupus erythematosus, Sjögren’s syndrome, and connective tissue diseases;
- Systemic vasculitis;
- Autoinflammatory diseases;
- Organ-specific and systemic autoimmune diseases;
- Immune checkpoint inhibitors (mechanisms and adverse effects);
- Immunosuppressive and immunomodulating therapies;
- Inherited and acquired immune deficiencies;
- Hypersensitivity and allergic responses;
- Transplantation immunology and graft rejection;
- Biomarkers and targeted therapies in immune-mediated diseases;
- Mechanisms of immune regulation and tolerance;
- Drug-induced autoimmunity and adverse reactions;
- Tumor immunology and antitumor immune responses;
- Others.
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- Arthritis: From Diagnosis to Treatment (Deadline: 20 November 2025)
- Clinical Updates on Rheumatoid Arthritis: 2nd Edition (Deadline: 30 November 2025)
- Rheumatoid Arthritis: Challenges, Innovations and Outcomes (Deadline: 15 December 2025)
- Clinical Treatment and Management of Rheumatic Diseases, Autoinflammatory Diseases, and Autoimmune Disorders (Deadline: 20 December 2025)
- Diagnosis and Treatment of Rheumatic Diseases (Deadline: 20 December 2025)
- Clinical Advances in Antiphospholipid Syndrome (APS) (Deadline: 30 December 2025)
- Autoimmune Diseases and Multisystem Inflammation: Pathophysiology and Therapeutic Strategies (Deadline: 30 December 2025)
- Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment (Deadline: 20 January 2026)
- Preventive Strategies and Novel Treatments for Rheumatoid Arthritis (Deadline: 20 January 2026)
- POTS, ME/CFS and Long COVID: Recent Advances and Future Direction (Deadline: 20 January 2026)
- Clinical Advances in Autoimmune Disorders (Deadline: 20 January 2026)
- Allergen-Specific Immunotherapy (AIT) for Allergic Diseases of the Respiratory Tract and Food Allergies (Deadline: 20 January 2026)
- Current and Emerging Therapies for Rheumatoid Arthritis (Deadline: 20 January 2026)
- Systemic Lupus Erythematosus: Current Trends and Therapeutic Innovations (Deadline: 15 February 2026)
- Rheumatoid Arthritis: Insights into Appropriate Diagnosis, Treatment and Management (Deadline: 20 February 2026)
- Targeted Treatment in Chronic Inflammatory Arthritis (Deadline: 20 February 2026)
- Allergic and Eosinophilic Diseases: Diagnosis, Treatment and Management (Second Edition) (Deadline: 25 February 2026)
- New Advances in Systemic Lupus Erythematosus (SLE) (Deadline: 20 March 2026)
- Translational Immunology in Clinical Medicine: From Preclinical Insights to Therapeutic Impact (Deadline: 25 March 2026)
- Diagnosis and Treatment of Sjogren’s Syndrome: 2nd Edition (Deadline: 15 April 2026)
- Pharmacotherapy and Patient Care in Rheumatoid Arthritis (Deadline: 15 April 2026)
- News in the Pathogenesis, Diagnosis and Treatment of Systemic Sclerosis (Deadline: 20 April 2026)
- Cardiovascular Risks in Autoimmune and Inflammatory Diseases (Deadline: 20 April 2026)
- Innate Immunity in Overdrive: Novel Insights into Autoinflammatory Syndromes (Deadline: 20 April 2026)
- Diagnosis and Treatment of Connective Tissue Diseases: A Clinician's Perspective: 2nd Edition (Deadline: 20 May 2026)
- Advances in Clinical Rheumatology—2nd Edition (Deadline: 20 May 2026)
- Sjogren’s Syndrome: Clinical Advances and Insights (Deadline: 7 June 2026)
- Hematoinflammatory Diseases: Bridging Autoimmunity and Autoinflammation (Deadline: 20 June 2026)
- Advances in Immunohematology: From Pathophysiology to Tailored Treatments (Deadline: 25 June 2026)
- Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life (Deadline: 30 July 2026)
Topical Collection
Following topical collection within this section is currently open for submissions:
