Immunopathogenesis of Bacterial Infection
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".
Deadline for manuscript submissions: closed (15 February 2023) | Viewed by 40160
Special Issue Editors
Interests: pathogen/host interactions; virulence factors; innate immune responses; wound healing; wound infection; diabetic foot ulcer; tumor biology/cancer therapeutics
Special Issue Information
Dear Colleagues,
Infection can be caused by a variety of pathogens, including (but not limited to) bacteria. Bacteria can gain entry into our body through wounds, bug bites, or the respiratory tract, where they can colonize and proliferate either intracellularly (within vacuoles or in the cytoplasm) or extracellularly in tissue within host cells. Through the production of a variety of virulence factors, they can impact and shape the host tissue inflammatory environment in such ways to facilitate their pathogenesis. In the past several decades, increasing evidence has revealed that host tissue defenses to bacterial infections depend on early innate immune responses, involving pattern-recognition receptors, canonical and/or non-canonical inflammasomes, cytokines, antimicrobial peptides, inflammatory leukocytes, etc., and adaptive immune responses involving B and T lymphocytes. Therefore, increasing our understanding of the mechanisms of interaction between pathogens and the host immune system is of great significance for early diagnosis, disease occurrence, and treatment.
This Special Issue aims to understand the immunopathogenesis of bacterial infections from a cellular and immunobiological perspective. We invite all scientists working in this area to contribute original research articles, reviews, communications, and short perspective articles on all aspects related to bacterial infection, disease mechanisms and virulence factors, the host-initiated innate and adaptive immune responses, and their pathological and/or beneficial consequences for the host or the infecting pathogen. We particularly welcome articles describing mechanistic insights at the molecular, cellular, or organismal level, as well as those providing translational value.
Prof. Dr. Sasha H. Shafikhani
Dr. Taeok Bae
Guest Editors
Manuscript Submission Information
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Keywords
- bacterial interactions
- wound infection
- innate immune responses
- cell death
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