Hemocyanins are respiratory dioxygen carrier proteins found in many arthropods including ancient terrestrial species such as spiders and scorpions as well as marine horseshoe crabs. As hemocyanins are highly conserved in this lineage, it is possible...
Plasmodium species are protozoan parasites causing the deadly malaria disease. They have developed effective resistance mechanisms against most antimalarial medication, causing an urgent need to identify new antimalarial drug targets. Ideally, new dr...
Carbapenem-resistant A. baumannii (CRAB) infection can cause acute host reactions that lead to high-fatality sepsis, making it important to develop new therapeutic options. Previously, we developed a short 9-meric peptide, Pro9-3D, with significant a...
Energy costs are now one of the leading criteria when procuring new computing hardware. Until recently, developers and users focused only on pure performance in terms of time-to-solution. Recent advances in energy-aware runtime systems render the opt...
The present contribution aims to give an insight into the main terrestrial and marine processes leading to delta flooding in the case of the transboundary Evros delta, located at the microtidal NE Aegean Sea, on the basis of recorded flood events in...
Hydrodiplomacy is the emerging framework where legal acts, based on technical data and information, aim to support commonly accepted solutions to water-related tensions among states with transboundary waters. In this research, hydrodiplomacy componen...
This study aimed to assess the effect of dietary supplementation of a mixture of botanical compounds and essential oil (Phyto AquaMeric, PAM) on the growth, immune and antioxidant parameters and environmental benefits in Nile tilapia. Two diets inclu...
The Tunca River is a transboundary watercourse between Türkiye and Bulgaria. It is the longest tributary of the Meriç River System (MRS) and joins the Meriç River in Türkiye after flowing through Bulgarian territory. In this s...
Background: Calcium hydroxide is a routinely used material for root canal disinfection during root canal treatment. Natural products have great potential in terms of their antibacterial effects. This study aimed to establish an effective alternative...
The T cell-dependent bispecific (TDB) antibody, anti-CD79b/CD3, targets CD79b and CD3 cell-surface receptors expressed on B cells and T cells, respectively. Since the anti-CD79b arm of this TDB binds only to human CD79b, a surrogate TDB that binds to...
Background and Objectives: An inter-arm systolic blood pressure difference (IASBPD) is defined as a blood pressure (BP) disparity of ≥10 mmHg between arms. IASBPDs are associated with an increased risk of cardiovascular disease (CVD). Similarly, visc...
Women infected with toxoplasmosis during pregnancy do not present symptoms in most cases, but the consequences of the congenital infection may be severe for the unborn child. Fetal damage can range from asymptomatic to severe neurological alterations...
A submersion from an almost contact Riemannian manifold to an almost Hermitian manifold, acting on the horizontal distribution by preserving both the metric and the structure, is, roughly speaking a contact-complex Riemannian submersion. This paper d...
The practice of physical activity in a variable climate during the same competition is becoming more and more common due to climate change and increasingly frequent climate disturbances. The main aim of this pilot study was to understand the impact o...
Being the predominant cause of disability, neurological diseases have received much attention from the global health community. Over a billion people suffer from one of the following neurological disorders: dementia, epilepsy, stroke, migraine, menin...
Visitors to zoos can have positive, neutral, or negative relationships with zoo animals. This makes human–animal interactions (HAIs) an essential component of welfare and an important consideration in species selection for zoo exhibits and in e...
Maintaining Gymnophiona in captivity provides opportunities to study the behaviour and life-history of this poorly known Order, and to investigate and provide species-appropriate welfare guidelines, which are currently lacking. This study focuses on...
The fast development of the offshore energy industry becomes an essential component of resilient economies in most of the countries around the North Sea, addressing an increasing demand for cost-efficient and environmentally safe energy sources. Offs...
This study aimed to investigate the effects of thermal stratification and complete mixing conditions on the bacterial diversity of a deep alkaline lake. For this purpose, the water and sediment samples were collected during the winter turnover and st...
Chymase is a protease stored in mast cell granules that produces angiotensin II (ANG II) from angiotensin I (ANG I) and is associated with tissue injury, inflammation, and remodeling, especially involving the cardiovascular system. As cardiovascular...
Stereotactic MR-guided Radiotherapy (MRgRT) is an interesting treatment option for adrenal gland metastases (AGM). We reviewed data from 12 consecutive patients treated with MRgRT for an AGM in our center between 14 November 2019 and 17 August 2021....
In this study, the aim was to develop a Likert-type scale to measure students’ attitudes toward the Information Technologies and Software course taught in secondary school. The developments in the field of science and technology and the changin...
Chronic venous disease (CVD) is a proqgressive and underestimated condition related to a vicious circle established by venous reflux and endothelial inflammation, leading to vein dilation and histology distortion, including loss of media tone. Sulode...
In Turkey, Science and Arts Centers (BİLSEM) were opened and put into practice in 1995 in order to support gifted and talented students who are different from their peers in academic, social, and artistic fields in addition to their formal educa...
Recurrent microsatellite stable (MSS) endometrial cancer has poor response to conventional therapy and limited efficacy with immune checkpoint monotherapy. We conducted a retrospective study of recurrent MSS endometrial cancer patients enrolled in im...
High-grade gliomas are the most fatal brain tumors. Grade 4 gliomas are called glioblastoma multiforme (GBM), which are associated with the poorest survival and a 5-year survival rate of less than 4%. Many patients with GBM developed concomitant cogn...
Waterborne pathogens represent one of the most widespread environmental concerns. Conventional disinfection methods, including chlorination and UV, pose several operational and environmental problems; namely, formation of potentially hazardous disinf...
A major archetype of artificial intelligence is developing algorithms facilitating temporal efficiency and accuracy while boosting the generalization performance. Even with the latest developments in machine learning, a key limitation has been the in...
The interest in the welfare of zoo animals, from both the public and the scientific community, has long been biased towards mammals. However, growing evidence of the complex behavioural repertoires of less charismatic animals, such as reptiles, revea...
MMVD, the most common cause of CHF in dogs, is a chronic disease with variable clinical signs, with some patients remaining asymptomatic while others develop CHF. Here, we aimed to evaluate serum proteins by proteomic analysis in dogs at different st...
The aim of this study was to investigate the water quality of rainwater harvesting ponds in Istanbul which are used for irrigation. For this purpose, samples were collected from 17 rainwater harvesting ponds during the summer of 2022 and selected phy...
Water-based polymer drilling fluids are commonly used for drilling long horizontal wells where eliminating the drilling fluid-related formation damage and minimizing the environmental impact of the drilling fluids are the main concerns. An experiment...
The UK’s TechDemoSat-1 (TDS-1), launched 2014, has demonstrated the use of global positioning system (GPS) signals for monitoring ocean winds and sea ice. Here it is shown, for the first time, that Galileo and BeiDou signals detected by TDS-1 s...
Background and Objectives: The mean platelet volume (MPV) represents a possible marker of platelet activation. There is an association between the platelet count (PC) and inflammation and platelet reactivity. We assessed the association between the M...
Purpose: To improve outcomes in localized osteosarcoma and to reduce the duration of preoperative chemotherapy, we conducted a phase ii trial assessing the efficacy of an intensive protracted regimen without methotrexate (API-AI regimen) in adolescen...
Under the impact of natural and anthropogenic climate variability, upwelling systems are known to change their properties leading to associated regime shifts in marine ecosystems. These often impact commercial fisheries and societies dependent on the...
Aspirin, synthesized and marketed in 1897 by Bayer, is one of the most widely used drugs in the world. It has a well-recognized role in decreasing inflammation, pain and fever, and in the prevention of thrombotic cardiovascular diseases. Its anti-inf...
The changing role of the pharmacist led to some improvements of pharmacy education worldwide these last years. Curricula have evolved and the content-based education has been converted into a competency-based education. The definition of a global pra...
Background and objective: Recently, some of the hemogram parameters were reported to predict early death in acute pulmonary embolism (PE). The aim of this study was to investigate the role of mean platelet volume (MPV) and MPV/platelet count ratio (M...
This study analyzes the impact of financial institution quality (FIQ) and financial stability (FSI) on trade-adjusted carbon emissions (TAE) in G7 countries from 2000 to 2022. It also examines whether green innovation (GI) and environmental taxes (ET...
Background and Objectives: Comorbidities, the coexistence of additional conditions with a primary disease, are increasingly prevalent, complicating disease management and clinical outcomes. While CTEPH is a well-studied condition in terms of risk fac...
Fischer–Tropsch synthesis (FTS) in a 3D-printed stainless steel (SS) microchannel microreactor was investigated using Fe@SiO2 catalysts. The catalysts were prepared by two different techniques: one pot (OP) and autoclave (AC). The mesoporous st...
Background and Objectives: Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, but their use is associated with a spectrum of immune-related adverse events (irAEs), including endocrine disorders. This study aims to investigate the...
Tunneling through weak rock masses under shallow urban overburdens is critically constrained by stand-up time. Conventional models for hydraulic impact hammers prioritize the excavation rate (Net Breaking Rate—NBR) but overlook a key operational bott...
We present a coupled large-eddy simulation (LES) and bed morpho-dynamics study to investigate the influence of sediment dynamics on the performance of a utility-scale marine hydrokinetic vertical-axis turbine (VAT) parametrized by an actuator surface...
Frozen storage modulates the progression of key oxidative and nitrogenous reactions within fish muscle. We therefore identify the drivers of quality degradation in filleted whiting (Merlangius merlangus) and Atlantic bonito (Sarda sarda) during 10-mo...
Predicting blast-induced vibrations in twin tunnels is challenging due to complex wave-cavity interactions, which render conventional scaled-distance (PPV-SD) models inadequate. This study introduces a hybrid empirical-probabilistic framework to quan...
Background and Objectives: This study aimed to examine the severity of misophonia symptoms in individuals diagnosed with obsessive–compulsive disorder (OCD) and to evaluate the pattern of the relationship between misophonia and OCD symptom seve...
Microalgae are an evolutionarily ancient and morphologically diverse group of photosynthetic eukaryotes, with taxonomic resolution complicated by environmentally driven phenotypic plasticity. This study merges deep learning and explainable artificial...
Amid the intensifying global mandate for sustainable aquafeed strategies, this study investigates the functional efficacy and biochemical implications of black soldier fly larvae oil (BLO), extracted via recently approved patent method depending on c...
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