Objectives: The purpose was to quantitatively examine brain structures using 7 Tesla MRI in the presence of visual loss caused by retinitis pigmentosa (RP) related to retinitis pigmentosa GTPase regulator (RPGR) gene pathogenic variants. Methods: Twe...
Purpose: To analyze the structural changes in the brain related to combined hearing and vision loss in patients with Usher syndrome (USH) obtained by 7 Tesla MRI. Methods: Twenty patients with a diagnosis of USH and fifteen normal age- and gender-mat...
Background/Objectives: To quantitatively assess lateral geniculate nucleus (LGN) volume using 7 Tesla MRI in patients with Stargardt disease (STGD). Methods: A total of 18 patients with STGD and 15 healthy volunteers were examined with a 7 Tesla MRI...
Perfusion measures of the total vasculature are commonly derived with gradient-echo (GE) dynamic susceptibility contrast (DSC) MR images, which are acquired during the early passes of a contrast agent. Alternatively, spin-echo (SE) DSC can be used to...
Objective: Ultra-high-field B0 ≥ 7 tesla (7T) cardiovascular magnetic resonance (CMR) offers increased resolution. However, electrocardiogram (ECG) gating is impacted by the magneto-hydrodynamic effect distorting the ECG trace. We explored the techni...
Magnetic Resonance Imaging (MRI) of the Optic Nerve is difficult due to the fine extended nature of the structure, strong local magnetic field distortions induced by anatomy, and large motion artefacts associated with eye movement. To address these p...
Diffusion magnetic resonance imaging (dMRI) allows for a non-invasive visualization and quantitative assessment of white matter architecture in the brain by characterizing restrictions on the random motion of water molecules. Ultra-high field MRI sca...
Purpose: The aim of this study was to assess the volumetry of the hippocampus in the Leber’s hereditary optic neuropathy (LHON) of blind patients. Methods: A total of 25 patients with LHON were randomly included into the study from the national...
Blood vessels of the brain provide the human brain with the required nutrients and oxygen. As a vulnerable part of the cerebral blood supply, pathology of small vessels can cause serious problems such as Cerebral Small Vessel Diseases (CSVD). It has...
In the published manuscript “Koush, Y.; Elliott, M.A. and Mathiak, K. Single Voxel Proton Spectroscopy for Neurofeedback at 7 Tesla. Materials 2011, 4, 1548-1563”, all estimates of T2* from the single voxel spectroscopy data were overestimated by a f...
This review article examines the current state of BOLD fMRI at a high magnetic field strength of 7 Tesla. The following aspects are covered: a short description of the BOLD contrast, spatial and temporal resolution, BOLD sensitivity, localization and...
Echo-planar imaging (EPI) in fMRI is regularly used to reveal BOLD activation in presubscribed regions of interest (ROI). The response is mediated by relative changes in T2* which appear as changes in the image pixel intensities. We have proposed an...
Background: In various cancer types, the first step towards extended metastatic disease is the presence of lymph node metastases. Imaging methods with sufficient diagnostic accuracy are required to personalize treatment. Lymph node metastases can be...
Purpose: We aimed to compare the volume of the lateral geniculate nucleus (LGN) in patients with different stages of retinitis pigmentosa (RP) with regard to age, sex and symmetry of the LGN. Methods: The investigated cohort included 13 patients with...
This paper investigated the correlation between magnetic resonance spectroscopic imaging (MRSI) and magnetic resonance fingerprinting (MRF) in glioma patients by comparing neuro-oncological markers obtained from MRSI to T1/T2 maps from MRF. Data from...
Automated lesion segmentation can support rapid and reproducible quantitative assessment and long-term monitoring of multiple sclerosis. Ultra-high-field 7T MRI provides increased spatial resolution and lesion visibility but introduces challenges for...
Animal studies show that sleep regulation depends on subcortical networks, but whether the connectivity between subcortical areas contributes to human sleep variability remains unclear. We investigated whether the effective connectivity between the L...
The implementation of clinical 7T MRI presents both opportunities and challenges for advanced medical imaging. This tutorial provides practical considerations and experiences with 7T MRI in clinical settings. We first explore the history and evolutio...
Background and Clinical Significance: CTC1-related cerebroretinal microangiopathy with calcifications and cysts (CRMCC), or Coats-plus syndrome, is an extremely rare autosomal recessive telomere-dysfunction disorder. A total of 29 cases in 15 reports...
Ultra-high-field 7 T time-of-flight MR angiography (TOF-MRA) provides detailed visualization of intracranial vasculature, but quantitative analysis is sensitive to intensity inhomogeneity and non-standardized post-processing. We present TOFR-VET (Tim...
Background/Objectives: The Achilles tendon enthesis (ATE) is a key load-transmitting structure that is frequently affected in musculoskeletal disorders, including insertional tendinopathy, overuse injuries and inflammatory enthesopathies. Reliable no...
Spectral correlations between metabolites in 31P magnetic resonance spectroscopy (MRS) spectra of human brain were compared at 3 and 7 Tesla, the two commonly used magnetic field strengths for clinical research. It was found that at both field streng...
The three-point-bending shape memory properties, microstructure, and magnetic properties of Fe40.95Ni28Co17Al11.5Ta2.5B0.05 (at.%) alloys were investigated. The magnetic results showed a martensitic transformation in the samples that were aged at 700...
Background/Objectives: To investigate the volume of the lateral geniculate nucleus (LGN) in patients with advanced retinitis pigmentosa (RP). Methods: Nineteen patients with advanced RP (mean age 52 years and mean duration of illness 357 months) and...
Background/Objectives: Cardiac magnetic resonance (CMR) imaging at 7 Tesla provides a substantially higher intrinsic signal-to-noise ratio compared with conventional 1.5 T and 3 T systems, potentially enabling higher spatial resolution, improved tiss...
The microstructure and superelastic response of an Fe41Ni28Co17Al11.5Ti2.5 (at.%) single crystal along the <100> orientation was investigated under tension at room temperature after aging at 600 °C for 24 h. From the superelastic results, t...
Tesla turbines are a kind of unconventional bladeless turbines, which utilize the viscosity of working fluid to rotate the rotor and realize energy conversion. They offer an attractive substitution for small and micro conventional bladed turbines due...
The importance of assessing neurochemical processes in the cetacean brain as a tool for monitoring their cognitive health and to indirectly model human neurodegenerative conditions is increasingly evident, although available data are largely semiquan...
Esterification, the reaction between carboxylic acids and alcohols that produces esters and water, plays a vital role in many industries, especially in biodiesel and pharmaceutical manufacturing. Traditional methods using homogeneous mineral acids po...
The use of natural zeolite clinoptilolite in preparing photocatalysts and its function in photocatalysis are discussed in this review. The importance of advanced oxidation processes (AOPs) and the potential of heterogeneous photocatalysis in removing...
Leber’s hereditary optic neuropathy (LHON) is a maternally inherited genetic disorder leading to severe and bilateral loss of central vision, with a young male predilection. In recent years, multiple studies examined structural abnormalities in...
Analogous to the evolution of biological sensor-systems, the progress in “medical sensor-systems”, i.e., diagnostic procedures, is paradigmatically described. Outstanding highlights of this progress are magnetic resonance imaging (MRI) and spectrosco...
Strong radiation from solar X-ray flares can produce increased ionization in the terrestrial D-region and change its structure. Moreover, extreme solar radiation in X-spectral range can create sudden ionospheric disturbances and can consequently affe...
Solar flares (SFs) and intense radiation can generate additional ionization in the Earth’s atmosphere and affect its structure. These types of solar radiation and activity create sudden ionospheric disturbances (SIDs), affect electronic equipment on...
A substantial number of individuals with clinical high-risk (CHR) mental state do not transition to psychosis. However, regardless of future diagnostic trajectories, many of these individuals develop poor social and occupational functional outcomes....
This study used a rat model of coronary artery reperfusion imaged with preclinical 7-tesla magnetic resonance imaging (7T-MRI) to evaluate cardiac function, myocardial deformation, and the impact of infarction-to-reperfusion time. Wistar rats were as...
Up to now, investigation of physical properties of ternary and higher nitridometalates has been severely hampered by challenges concerning phase purity and crystal size. Employing a modified lithium flux technique, we are now able to prepare sufficie...
This paper explores and ranks the key performance indicators of multi-criteria decision-making in the process of selecting renewable energy sources (RES). Different categories of factors (e.g., political, legal, technological, economic and financial,...
Using metakaolin (MK) in concrete with magnetized water (MW) has a high possibility to enhance concrete suitability. In this study, the effect of using MK and MW on concrete characteristics was studied through testing twelve concrete mixes. Seven rat...
Purpose: Diffuse low-grade gliomas (DLGGs) are low-malignancy brain tumors originating from the glial cells of the brain growing continuously and infiltratively along the neural axons and infiltrating the surrounding brain tissue. DLGGs usually trans...
In this study, the effect of aging heat treatment on the superelastic properties and microstructure of [001]-oriented Fe41Ni28Co17Al11.5Ti1.25Nb1.25 (at.%) single crystals was investigated using the cyclic superelastic strain test and a transmission...
We investigated the presence of misfolded alpha-Synuclein (α-Syn) in minor salivary gland biopsies in relation to substantia nigra pars compacta (SNc) damage measured using magnetic resonance imaging in patients with isolated rapid eye movement...
Quantitative susceptibility mapping (QSM) is used to obtain quantitative magnetic susceptibility maps of materials from magnitude and phase images acquired by three-dimensional gradient-echo using inverse problem-solving. Few preclinical studies have...
In this paper, we detail how microantennae dedicated to Magnetic Resonance Imaging (MRI) can benefit from the advantages offered by polymer substrates, especially flexibility and dielectric properties. We present a monolithic and wireless design base...
An icosahedral closo-B122− scaffold based nano-sized assembly capable of carrying a high payload of Gd3+-chelates in a sterically crowded configuration is developed by employing the azide-alkyne click reaction. The twelve copies of DO3A-t-Bu-ester li...
Pancreatic ductal adenocarcinoma (PDA) is characterized by a pronounced fibroinflammatory stromal reaction consisting of inordinate levels of hyaluronan (HA), collagen, immune cells, and activated fibroblasts that work in concert to generate a robust...
One of the most important challenges in developing the concrete industry is to use sustainable materials that are able to improve concrete properties. Magnetized water (MW) is a type of water that can replace tap water (TW) in conventional concrete a...
Buildings can be made more user-friendly and secure by putting “smart” design strategies and technology processes in place. Such strategies and processes increase energy efficiency, make it possible to use resources rationally, and lower...
Pelizaeus–Merzbacher disease (PMD) is an X-linked recessive disorder of the central nervous system. We performed 7 Tesla magnetic resonance imaging of the brain in Tama rats, a rodent PMD model, and control rats, as well as evaluated the diagno...
The risk of accidental dislodgement of robot-operated surgical mechanisms can lead to morbidity or mortality. The force and torque applied by a 3.0-tesla scanner on an ultrasonic motor are not fully known. The force and torque may displace the motor,...
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