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Diagnostics
Special Issues
Cardiovascular Imaging, 2nd Edition
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Cardiovascular Imaging, 2nd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 1338

Special Issue Editor

Prof. Dr. Riemer H.J.A. Slart

E-Mail Website
Guest Editor
Medical Imaging Center, Department of Nuclear Medicine & Molecular Imaging, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands
Interests: cardiovascular diseases; PET/CT; SPECT/CT; (hybrid) imaging; multimodality imaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to elucidate the role of noninvasive imaging modalities in the diagnosis and imaging-based therapeutic management of cardiovascular diseases, with particular attention given to not only the standard of care but also developments that hold relevance for the near future. We encourage authors to submit both preclinical and clinical studies in this field. Clinical studies may include systematic reviews/meta-analyses, retrospective studies, and prospective studies emphasizing the role of and need for imaging techniques in primary diagnosis, treatment response, and disease relapse.

Prof. Dr. Riemer H.J.A. Slart
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular imaging
  • noninvasive imaging
  • diagnosis
  • prognosis
  • marker

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Published Papers (3 papers)

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19 pages, 1284 KB  
Systematic Review
Human In Vivo Cardiac Magnetic Resonance Imaging at 7 T: Feasibility, Applications, and Current Limitations—A Systematic Review
by Arosh S. Perera Molligoda Arachchige, Gabriel Amorim Moreira Alves, Ayça Zal, Giulia D’Acunto, Maciej Węglarz, Oana-Georgiana Voicu, Erica Maffei and Filippo Cademartiri
Diagnostics 2026, 16(6), 937; https://doi.org/10.3390/diagnostics16060937 - 22 Mar 2026
Viewed by 447
Abstract
Background/Objectives: Cardiac magnetic resonance (CMR) imaging at 7 Tesla provides a substantially higher intrinsic signal-to-noise ratio compared with conventional 1.5 T and 3 T systems, potentially enabling higher spatial resolution, improved tissue contrast, and advanced metabolic imaging. However, clinical translation remains limited by [...] Read more.
Background/Objectives: Cardiac magnetic resonance (CMR) imaging at 7 Tesla provides a substantially higher intrinsic signal-to-noise ratio compared with conventional 1.5 T and 3 T systems, potentially enabling higher spatial resolution, improved tissue contrast, and advanced metabolic imaging. However, clinical translation remains limited by technical challenges associated with ultra-high-field operation. This systematic review aimed to synthesize current human in vivo evidence on the feasibility, applications, and methodological limitations of 7-T cardiovascular MRI. Methods: A PRISMA-guided systematic search of PubMed, Cochrane Library, Web of Science, and Scopus was conducted from database inception through January 2025. Studies reporting human in vivo cardiovascular MRI at 7 Tesla were included. Data regarding study design, sample characteristics, imaging applications, feasibility, quantitative findings, and reported limitations were extracted and qualitatively synthesized. Results: Sixty-five studies met inclusion criteria, predominantly small prospective cohorts (mean sample size = 13), largely involving healthy volunteers. Across diverse applications—including coronary MR angiography, cine imaging, valvular assessment, vascular imaging, flow quantification, myocardial tissue characterization, and multinuclear (31P, 23Na, 39K) imaging—7-T CMR was consistently feasible and capable of producing high-quality images. Quantitative ventricular and vascular measurements were generally concordant with lower field strengths. Incremental benefits were most apparent in high-resolution structural imaging and metabolic applications, whereas routine functional and flow assessments showed limited additional advantages. No serious adverse events were reported. Conclusions: Human cardiovascular MRI at 7 Tesla represents a technically feasible research and early translational platform with selective advantages over established field strengths. Further advances in radiofrequency technology, protocol harmonization, and larger disease-focused studies are required to clarify its potential clinical role. Full article
(This article belongs to the Special Issue Cardiovascular Imaging, 2nd Edition)
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5 pages, 4502 KB  
Interesting Images
Unrecognized Atrial Septal Defect Presenting with Postoperative Occipital Infarction
by Jasper Lin, Vinicius Carraro do Nascimento, Jeremy Hefford, Tony Vo and Maria Gabriela Matta
Diagnostics 2026, 16(6), 907; https://doi.org/10.3390/diagnostics16060907 - 19 Mar 2026
Viewed by 265
Abstract
A 49-year-old woman developed acute homonymous hemianopia three days after elective surgery. Neuroimaging confirmed an embolic right occipital infarction. Transthoracic echocardiography demonstrated early bubble passage, and transesophageal imaging identified a 4.6 mm ostium secundum atrial septal defect. The defect was successfully closed percutaneously [...] Read more.
A 49-year-old woman developed acute homonymous hemianopia three days after elective surgery. Neuroimaging confirmed an embolic right occipital infarction. Transthoracic echocardiography demonstrated early bubble passage, and transesophageal imaging identified a 4.6 mm ostium secundum atrial septal defect. The defect was successfully closed percutaneously with complete shunt resolution. This case emphasizes the value of targeted multimodality imaging in uncovering occult interatrial shunts and highlights presumed paradoxical embolism as a potential mechanism of postoperative or cryptogenic stroke. Full article
(This article belongs to the Special Issue Cardiovascular Imaging, 2nd Edition)
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3 pages, 680 KB  
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Rare Combination of Partial ARCAPA and Dual LAD: Insights into Complex Coronary Variants
by Chiara Morelli, Francesca Troise, Alessia Spitaleri, Sterpeta Guerra and Nicola Maggialetti
Diagnostics 2026, 16(6), 886; https://doi.org/10.3390/diagnostics16060886 - 17 Mar 2026
Viewed by 268
Abstract
This case report highlights the coexistence of two rare coronary artery anomalies assessed by computed coronary tomography angiography (CCTA). We present the case of a 51-year-old hypertensive patient with a type II double left anterior descending artery (LAD) and an anomalous infundibular branch [...] Read more.
This case report highlights the coexistence of two rare coronary artery anomalies assessed by computed coronary tomography angiography (CCTA). We present the case of a 51-year-old hypertensive patient with a type II double left anterior descending artery (LAD) and an anomalous infundibular branch originating from the pulmonary artery (partial ARCAPA). This association may have contributed to a limited ischemic burden, explaining the patient’s asymptomatic state. Knowledge of these rare coronary anatomies is essential for accurate diagnosis and management. Full article
(This article belongs to the Special Issue Cardiovascular Imaging, 2nd Edition)
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