Compounds with Medicinal Value

Dear Colleagues,

In industrialized countries over the last few decades, there has been a significant increase in infectious; cardiovascular, inflammatory, and neurodegenerative diseases; as well as different forms of cancer, diabetes, and so on.

Between them, microbial infections and cancer are still the major causes of death among the world’s population due to increased bacterial resistance phenomena and the development of resistance to chemotherapeutics. For these reasons, there is an urgent need to design and synthesize new antimicrobial agents, particularly those with antibacterial activity, and particularly against Gram-negative pathogens that could be used to fight drug resistance, and also for new antineoplastic drugs with higher selectivity on tumoral cells, which are able to overcome cancer cells’ resistance with minimal side effects.

Recently, some delivery systems have proved particulary effective as antimicrobial and anticancer carriers due to targeted drug delivery at the action sites, reduced drug-resistance and side effects, and an increased therapeutic index.

Potential topics for manuscripts include the following:

• The design, synthesis, and biological evaluation of anticancer agents;
• The design, synthesis, and biological evaluation of antimicrobial agents;
• Delivery systems and nanosystems for targeted cancer and antimicrobial therapy...

Prof. Dr. Maria Stefania Sinicropi
Topic Editor