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39,631 Results Found

  • Article
  • Open Access
3 Citations
2,920 Views
16 Pages

Structure-Dependent Toxicokinetics of Selected Pyrrolizidine Alkaloids In Vitro

  • Julia Buchmueller,
  • Florian Kaltner,
  • Christoph Gottschalk,
  • Maria Maares and ,
  • Albert Braeuning and
  • Stefanie Hessel-Pras
  • + 1 author+ 0 author

16 August 2022

Phytochemicals like pyrrolizidine alkaloids (PAs) can affect the health of humans and animals. PAs can occur for example in tea, honey or herbs. Some PAs are known to be cytotoxic, genotoxic, and carcinogenic. Upon intake of high amounts, hepatotoxic...

(This article belongs to the Special Issue Cytochrome P450 (CYP))
  • Article
  • Open Access
3,358 Views
23 Pages

19 December 2021

Although many families of integration methods have been successfully developed with desired numerical properties, such as second order accuracy, unconditional stability and numerical dissipation, they are generally implicit methods. Thus, an iterativ...

(This article belongs to the Topic Advances in Dynamics of Building Structures)
  • Article
  • Open Access
993 Views
14 Pages

Structurally Dependent Self-Propulsion Behaviors of Pt-SiO2 Micromotors

  • Le Zhou,
  • Qian Zhao,
  • Hongwen Zhang,
  • Haoming Bao and
  • Weiping Cai

4 January 2026

The structural dependence of self-propelled motion in micro/nanomotors is essential for effectively predicting and controlling their dynamic behaviors. In this study, platinum–silica (Pt-SiO2) micromotors, with structures ranging from spherical...

(This article belongs to the Section Nanofabrication and Nanomanufacturing)
  • Review
  • Open Access
47 Citations
10,974 Views
17 Pages

Natural Products Targeting Amyloid Beta in Alzheimer’s Disease

  • Joo-Hee Lee,
  • Na-Hyun Ahn,
  • Su-Bin Choi,
  • Youngeun Kwon and
  • Seung-Hoon Yang

26 February 2021

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by severe brain damage and dementia. There are currently few therapeutics to treat this disease, and they can only temporarily alleviate some of the symptoms. The pathogenesis of A...

(This article belongs to the Special Issue Amyloid-β: Structure, Function, and Pathophysiological Significance in Neurodegenerative Diseases 2.0)
  • Article
  • Open Access
1 Citations
2,407 Views
19 Pages

The Structure-Dependent Dynamic Performance of a Twin-Ball-Screw Drive Mechanism via a Receptance Coupling Approach

  • Uwayezu Marie Chantal,
  • Hong Lu,
  • Qi Liu,
  • Tao Jiang and ,
  • Jiji He,
  • Shuaiwei Gu and
  • Gashema Gaspard
  • + 2 authors+ 0 author

15 June 2024

The drive at the center of gravity (DCG) concept-based twin-ball-screw drive mechanism (TBSDM) is vital in automated factories for its robustness and reliability. However, changes in the worktable mass or position result in changes in the center of g...

  • Article
  • Open Access
4 Citations
3,344 Views
17 Pages

18 May 2021

Pyrrolizidine alkaloids (PAs) are a group of secondary plant metabolites being contained in various plant species. The consumption of contaminated food can lead to acute intoxications in humans and exert severe hepatotoxicity. The development of jaun...

(This article belongs to the Special Issue Natural Compounds in Plant-Based Food)
  • Article
  • Open Access
2,814 Views
21 Pages

TL-φ algorithms are newly developed explicit structure-dependent integration algorithms utilized for solving the temporally discretized equations of motion. In contrast to the existing algorithms, the most significant improvement of TL-φ algo...

(This article belongs to the Special Issue Research on Statics and Dynamics of Structures)
  • Article
  • Open Access
26 Citations
3,508 Views
12 Pages

Pyrrolizidine Alkaloids Induce Cell Death in Human HepaRG Cells in a Structure-Dependent Manner

  • Josephin Glück,
  • Julia Waizenegger,
  • Albert Braeuning and
  • Stefanie Hessel-Pras

28 December 2020

Pyrrolizidine alkaloids (PAs) are a group of secondary metabolites produced in various plant species as a defense mechanism against herbivores. PAs consist of a necine base, which is esterified with one or two necine acids. Humans are exposed to PAs...

(This article belongs to the Special Issue Food Toxicants)
  • Article
  • Open Access
13 Citations
4,116 Views
16 Pages

Active Transport of Hepatotoxic Pyrrolizidine Alkaloids in HepaRG Cells

  • Anne-Margarethe Enge,
  • Florian Kaltner,
  • Christoph Gottschalk,
  • Albert Braeuning and
  • Stefanie Hessel-Pras

1,2-unsaturated pyrrolizidine alkaloids (PAs) are secondary plant metabolites occurring as food contaminants that can cause severe liver damage upon metabolic activation in hepatocytes. However, it is yet unknown how these contaminants enter the cell...

(This article belongs to the Special Issue Molecular Biology and Chemistry of Mycotoxins and Phytotoxins)
  • Article
  • Open Access
2 Citations
4,002 Views
17 Pages

16 February 2018

Although the risk management of agricultural firms is important, studies on the extreme risk dependence among agribusiness firms are minimal due to the diversity and complexity of the risks faced by agricultural firms. In this study, we developed a h...

(This article belongs to the Special Issue Sustainable Agribusiness Decision making model in Belt and Road Green Development)
  • Article
  • Open Access
3 Citations
1,804 Views
11 Pages

Graph Convolution Network over Dependency Structure Improve Knowledge Base Question Answering

  • Chenggong Zhang,
  • Daren Zha,
  • Lei Wang,
  • Nan Mu and ,
  • Chengwei Yang,
  • Bin Wang and
  • Fuyong Xu
  • + 2 authors+ 0 author

Knowledge base question answering (KBQA) can be divided into two types according to the type of complexity: questions with constraints and questions with multiple hops of relationships. Previous work on knowledge base question answering have mostly f...

(This article belongs to the Special Issue Advances in Intelligent Data Analysis and Its Applications)
  • Article
  • Open Access
415 Views
39 Pages

3 September 2026

Efficient workflow scheduling is essential for improving testing efficiency in large-scale Vehicle-to-Everything (V2X) protocol conformance testing. Existing directed acyclic graph (DAG) schedulers treat all test components uniformly, overlooking the...

  • Article
  • Open Access
8 Citations
2,362 Views
29 Pages

8 September 2023

In recent years, the use of functionally graded materials has been the focus of several studies due to their intrinsic ability to be tailored according to the requirements of structures while minimising abrupt stress transitions commonly found in lam...

(This article belongs to the Special Issue Multifunctional Composites, Volume III)
  • Article
  • Open Access
5 Citations
6,110 Views
18 Pages

27 April 2015

This paper presents the important features of structure-dependent model predictive control (MPC)-based approaches for automatic generation control (AGC) considering network topology. Since power systems have various generators under different topolog...

  • Article
  • Open Access
3 Citations
1,665 Views
22 Pages

19 May 2025

With the growing global emphasis on sustainable development goals, Environmental, Social, and Governance (ESG) factors have emerged as critical considerations in shaping economic policies and strategies. This study employs the ARMA-eGARCH-skewed t an...

(This article belongs to the Section Economic and Business Aspects of Sustainability)
  • Article
  • Open Access
422 Views
15 Pages

Seasonal Occurrence and UV-Based Oxidative Removal of Odorants in Surface Water: Insights into Structure-Dependent Reactivity

  • Junkai Feng,
  • Congcong Li,
  • Hao Jiao,
  • Xiaodong Xin and ,
  • Ruibao Jia and
  • Weiqiang Zhu
  • + 1 author+ 0 author

6 August 2026

Odorants present a persistent challenge in drinking water treatment due to their low odor threshold concentrations (OTCs) and their resistance to conventional processes. This study investigated the seasonal occurrence of eight odorants across 20 surf...

(This article belongs to the Special Issue Low-Carbon Biotechnologies for Water Quality and Public Health: From Nitrogen Removal to Emerging Contaminant Mitigation)
  • Article
  • Open Access
  • Best Paper Award
142 Citations
13,746 Views
19 Pages

12 January 2023

Plant proteins are constantly gaining attention as potential substitutes for dairy proteins, due to their suitable functionality and nutritional value. This study was designed to compare the structural and functional responses of different plant prot...

(This article belongs to the Special Issue Milk and Dairy Products: Linking the Chemistry, Structure, Processing, and Food Properties)
  • Feature Paper
  • Article
  • Open Access
3 Citations
2,639 Views
15 Pages

2 September 2021

Nonlinear drag force has been a research frontier in complex gas-solid systems. The literature has reported that the commonly-used drag correlations often overestimate drag force and, thus, cause unrealistic homogeneous flow structures in gas-solid f...

  • Article
  • Open Access
8 Citations
5,184 Views
11 Pages

14 January 2019

Fe2O3–ZrO2 catalysts with different morphologies (nanoplates (HZNPs), nanorods (HZNRs), nanocubes (HZNCs), and nanotubes (HZNTs)) were prepared by a hydrothermal method to investigate the effect of the morphology on the catalytic performance in...

  • Article
  • Open Access
9 Citations
2,750 Views
15 Pages

12 December 2023

Carbon nanotube (CNT)-based networks have wide applications, in which structural design and control are important to achieve the desired performance. This paper focuses on the mechanism behind the structure-dependent mechanical performance of a CNT-b...

(This article belongs to the Section 2D and Carbon Nanomaterials)
  • Article
  • Open Access
374 Views
18 Pages

Structure-Dependent Innate Immune Compatibility of Sup35 G7-Derived Self-Assembling Peptide Nanomaterials in an Immune-Compatibility Assessment

  • Jinglin Song,
  • Shixiong Shen,
  • Langzhi He,
  • Hasen Bilige and ,
  • Chen Li,
  • Yuedan Wang,
  • Wenjun Ma and
  • Yun Wang
  • + 3 authors+ 0 author

25 August 2026

Objective: Self-assembling peptide nanomaterials are increasingly investigated as modular platforms for vaccine delivery and immune modulation. However, their structure-dependent interactions with immune cells remain insufficiently defined, limiting...

(This article belongs to the Section Vaccine Design, Development, and Delivery)
  • Article
  • Open Access
11 Citations
6,184 Views
11 Pages

Orientation-Dependent Reflection of Structurally Coloured Butterflies

  • Sigrid Zobl,
  • Bodo D. Wilts,
  • Willi Salvenmoser,
  • Peter Pölt and ,
  • Ille C. Gebeshuber and
  • Thorsten Schwerte
  • + 1 author+ 0 author

The photonic structures of butterfly wing scales are widely known to cause angle-dependent colours by light interference with nanostructures present in the wing scales. Here, we quantify the relevance of the horizontal alignment of the butterfly wing...

  • Article
  • Open Access
8 Citations
3,461 Views
13 Pages

25 March 2020

Consumers are heterogeneous in their inertial responses to previous consumptions. Information on consumers’ structural state-dependence is valuable for evaluating consumers’ habit-forming strength and thus can be used for encouraging more...

(This article belongs to the Section Economic and Business Aspects of Sustainability)
  • Article
  • Open Access
1 Citations
887 Views
13 Pages

Structure-Dependent Parameter Trade-Off Optimization on RonCoff and Power Compression of AlGaN/GaN HEMTs for RF Switch Application

  • Xu Zou,
  • Meng Zhang,
  • Ling Yang,
  • Bin Hou and ,
  • Mei Wu,
  • Chupeng Yi,
  • Hao Lu,
  • Mao Jia,
  • Qian Yu and
  • Yue Hao
  • + 7 authors+ 2 authors

27 January 2026

This paper presents, for the first time, the structure-dependent parameter trade-off optimization on figure-of-merit (RonCoff) and power compression of AlGaN/GaN high electron mobility transistors (HEMTs) for radio frequency (RF) switch applications....

(This article belongs to the Special Issue RF and Power Electronic Devices and Applications, 2nd Edition)
  • Feature Paper
  • Article
  • Open Access
9 Citations
4,498 Views
18 Pages

We study the dependence structure of share price returns among the Beijing Bank, Ningbo Bank, and Nanjing Bank using copula models. We use the normal, Student’s t, rotated Gumbel, and symmetrized Joe-Clayton (SJC) copula models to estimate the...

(This article belongs to the Special Issue Empirical Finance)
  • Article
  • Open Access
671 Views
21 Pages

21 August 2026

Per- and polyfluoroalkyl substances (PFAS) are persistent, structurally diverse contaminants whose ecological hazard assessment remains challenging, particularly for primary producers. Conventional growth-based algal bioassays often overlook subletha...

(This article belongs to the Section Ecotoxicology)
  • Article
  • Open Access
10 Citations
2,616 Views
10 Pages

29 March 2024

Poly(vinylidene fluoride) (PVDF) is predominantly characterized by alternating CH2 and CF2 units in a polymer backbone, originating from the head-to-tail addition of monomers or regular propagation. Due, to a small extent, to inverse monomer addition...

(This article belongs to the Special Issue Themed Issue Dedicated to Prof. Bernard Boutevin)
  • Article
  • Open Access
21 Citations
5,543 Views
12 Pages

2 February 2022

Deep learning methods for RNA secondary structure prediction have shown higher performance than traditional methods, but there is still much room to improve. It is known that the lengths of RNAs are very different, as are their secondary structures....

(This article belongs to the Special Issue Deep Learning for Molecular Structure Modelling)
  • Article
  • Open Access
5 Citations
4,093 Views
14 Pages

10 November 2020

The molecular design of short peptides to achieve a tailor-made functional architecture has attracted attention during the past decade but remains challenging as a result of insufficient understanding of the relationship between peptide sequence and...

(This article belongs to the Section Materials Science)
  • Review
  • Open Access
359 Citations
24,858 Views
23 Pages

RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution

  • Sangita Venkataraman,
  • Burra V. L. S. Prasad and
  • Ramasamy Selvarajan

10 February 2018

RNA dependent RNA polymerase (RdRp) is one of the most versatile enzymes of RNA viruses that is indispensable for replicating the genome as well as for carrying out transcription. The core structural features of RdRps are conserved, despite the diver...

(This article belongs to the Special Issue Structure-Function Relationships in Viral Polymerases)
  • Article
  • Open Access
4 Citations
3,577 Views
17 Pages

11 October 2019

Failure mode and effect analysis (FMEA) is a structured technique for identifying risks that may occur during a given stage of a system’s life cycle. However, the use of the risk priority number (RPN) in traditional FMEA results in difficulties...

(This article belongs to the Section Applied Industrial Technologies)
  • Article
  • Open Access
8 Citations
3,537 Views
12 Pages

30 August 2023

This paper aims to study the intricate interplay among the digital economy, industrial structure, and the degree of dependence on foreign trade. We utilize panel data from 284 prefecture-level cities in China spanning from 2011 to 2019 to comprehensi...

(This article belongs to the Special Issue Circular Economy and Economy Sustainability)
  • Article
  • Open Access
953 Views
31 Pages

A Structural Response Prediction Method Based on Data-Driven for Offshore Wind Turbines Considering Time-Dependent Corrosion Damage

  • Yu Cao,
  • Xinbiao Zhou,
  • Jiangong Yang,
  • Feng Liu and ,
  • Rihan Na,
  • Donghai Xie and
  • Yong Bai
  • + 2 authors+ 0 author

The reliability of structural safety assessments for offshore wind turbines is often compromised by time-dependent corrosion effects and the high computational cost of fluid–structure interaction analysis. This study proposes a data-driven fram...

(This article belongs to the Special Issue Offshore Renewable Energy: Waves, Tides, and Wind)
  • Article
  • Open Access
18 Citations
3,174 Views
7 Pages

Size-Dependent Structural Properties of a High-Nb TiAl Alloy Powder

  • Binglin Liu,
  • Maosong Wang,
  • Yulei Du and
  • Jingxiao Li

1 January 2020

TiAl-based alloys are promising light weight structural materials for high temperature applications in the field of aerospace. Recently, fabrication technologies starting from powders including powder metallurgy and additive manufacturing have been d...

(This article belongs to the Section Materials Physics)
  • Article
  • Open Access
31 Citations
4,265 Views
22 Pages

10 January 2024

Aspect-based sentiment analysis is a fine-grained task where the key goal is to predict sentiment polarities of one or more aspects in a given sentence. Currently, graph neural network models built upon dependency trees are widely employed for aspect...

(This article belongs to the Special Issue Emerging Machine Learning Techniques in Industrial Internet of Things)
  • Article
  • Open Access
2 Citations
2,955 Views
24 Pages

Modelling Dependency Structures of Carbon Trading Markets between China and European Union: From Carbon Pilot to COVID-19 Pandemic

  • Mingzhi Zhang,
  • Hongyu Liu,
  • Jianxu Liu,
  • Chao Chen and ,
  • Zhaocheng Li,
  • Bowen Wang and
  • Songsak Sriboonchitta
  • + 2 authors+ 0 author

5 December 2022

The exploration of the dependency structure of the Chinese and EU carbon trading markets is crucial to the construction of a globally harmonized carbon market. In this paper, we studied the characteristics of structural interdependency between China&...

(This article belongs to the Section Mathematical Analysis)
  • Review
  • Open Access
69 Citations
17,068 Views
26 Pages

23 March 2018

Due to the enhanced piezoelectric properties, excellent mechanical properties and tunable electric properties, one-dimensional (1D) piezoelectric materials have shown their promising applications in nanogenerators (NG), sensors, actuators, electronic...

(This article belongs to the Special Issue 1D Nanostructure-Based Piezo-Generators)
  • Article
  • Open Access
11 Citations
3,999 Views
23 Pages

10 May 2021

Besides the design freedom offered by additive manufacturing, another asset lies within its potential to accelerate product development processes by rapid fabrication of functional prototypes. The premise to fully exploit this benefit for lightweight...

(This article belongs to the Special Issue Experimental Testing and Numerical Simulation of Polymer-Based Additive Manufacturing Parts)
  • Article
  • Open Access
5 Citations
2,790 Views
10 Pages

Structure-Dependent Eco-Toxicity of Vegetable Tannin

  • Faming He,
  • Liangqiong Peng,
  • Wenjun Long,
  • Xiaofeng Jiang and
  • Wenhua Zhang

21 April 2022

Vegetable tannin is widely applied in various industries, in agriculture, and in water treatment as a natural polyphenolic compound; however, little data has been collected concerning the relationship between structure and eco-toxicity. Here, the tox...

(This article belongs to the Special Issue Advanced Technology for the Biomass-Based Chemicals, Fuels and Materials)
  • Article
  • Open Access
423 Views
14 Pages

28 July 2026

This study examines the structural drivers of Hungary’s electricity import dependence and assesses how domestic generation, regional trade exposure, and system-level constraints shape electricity security. The analysis combines a targeted liter...

(This article belongs to the Section C: Energy Economics and Policy)
  • Article
  • Open Access
1 Citations
1,999 Views
18 Pages

11 May 2024

An integrated model that considers multiphysics is necessary to accurately analyze the time-dependent response of hydraulic structures on soft foundations. This study develops an integrated superstructure–foundation–backfills model and in...

(This article belongs to the Special Issue Remote Sensing, Artificial Intelligence and Deep Learning in Hydraulic Structure Safety Monitoring)
  • Article
  • Open Access
26 Citations
4,773 Views
14 Pages

Anthocyanins Prevent AAPH-Induced Steroidogenesis Disorder in Leydig Cells by Counteracting Oxidative Stress and StAR Abnormal Expression in a Structure-Dependent Manner

  • Jun Hu,
  • Xusheng Li,
  • Naijun Wu,
  • Cuijuan Zhu and ,
  • Xinwei Jiang,
  • Kailan Yuan,
  • Yue Li,
  • Jianxia Sun and
  • Weibin Bai
  • + 4 authors+ 0 author

17 February 2023

Testosterone deficiency may increase the risk of sexual dysfunction and the failure of spermatogenesis. Oxidative stress that is derived from the destruction of homeostasis, disease, and exposure to contaminants can damage the steroidogenicity proces...

(This article belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
  • Article
  • Open Access
4 Citations
2,545 Views
17 Pages

8 April 2024

Mechanical interfaces are prevalent in industries like aerospace and maritime, where the normal contact stiffness on these surfaces is a crucial component of the overall stiffness of mechanical structures. From the perspective of structural mechanics...

(This article belongs to the Section Mechanical Engineering)
  • Article
  • Open Access
4 Citations
1,925 Views
16 Pages

Unveiling Frequency-Dependent Electromechanical Dynamics in Ferroelectric BaTiO3 Nanofilm with a Core-Shell Structure

  • Mingran Zhang,
  • Rui Ma,
  • Jianqiang Zhou,
  • Yuanxiang Zhang and ,
  • Jie Wang and
  • Shengbin Weng
  • + 1 author+ 0 author

12 November 2024

Diverse domain patterns significantly influence the nonlinear electromechanical behaviors of ferroelectric nanomaterials, with polarization switching under strong electric fields being inherently a frequency-dependent phenomenon. Nevertheless, resear...

(This article belongs to the Special Issue Synthesis, Properties and Application of Thin Films, Nanofilms and Nanocrystals)
  • Article
  • Open Access
11 Citations
3,244 Views
13 Pages

We propose a simple three-factor pricing model, consisting of a local stock market index, a global REIT market index, and a global stock market index, to examine the dependence structure of conditional volatilities in the real estate investment trust...

(This article belongs to the Section Financial Markets)
  • Article
  • Open Access
2 Citations
699 Views
18 Pages

Soil-Dependent Optimization of TMD- and Inerter-Based Devices for Seismic Retrofit of Multi-Story Structures

  • Konstantinos Kapasakalis,
  • Georgios Florakis,
  • Maria Spanea and
  • Evangelos Sapountzakis

13 March 2026

Distributed passive vibration control systems (VCSs) offer an attractive solution for improving the seismic response of multi-story buildings, particularly in seismic retrofit applications and when soil–structure interaction (SSI) effects are e...

(This article belongs to the Special Issue Advances in Earthquake Engineering and Seismic Resilience)
  • Article
  • Open Access
3 Citations
1,925 Views
32 Pages

Terms of Trade and the Structural Sustainability of the Mining Sector in a Resource-Dependent Economy

  • Antonio Rafael Rodríguez Abraham,
  • Hugo Daniel García Juárez,
  • Ingrid Estefani Sánchez García,
  • Carlos Enrique Mendoza Ocaña and
  • Guillermo Paris Arias Pereyra

11 March 2026

This study investigates whether external terms of trade (TOT) and mining-sector GDP in Peru share a stable long-run relationship. Although mining has played a central role in the country’s growth trajectory, its performance remains highly expos...

  • Article
  • Open Access
7 Citations
5,265 Views
20 Pages

1 June 2020

This paper examines the joint movement and tail dependence structure between the pair of foreign exchange rates (EUR, USD and GBP) against the GHS, using daily exchange rates data expressed in GHS per unit of foreign currencies (EUR, USD and GBP) bet...

(This article belongs to the Special Issue Credit Risk Modeling and Management in Banking Business)
  • Article
  • Open Access
8 Citations
6,534 Views
20 Pages

26 August 2019

Long-term care (LTC) encompasses a set of services provided to impaired and dependent elderly people. To assess the level of the dependence several scales are used, including activities of daily living (ADL), instrumental ADL (IADL) and functional li...

  • Article
  • Open Access
10 Citations
3,770 Views
16 Pages

4 May 2022

Understanding material behavior is key to discovering innovative applications in any field. Regardless of the exciting mechanical properties of polyurea, there has been a limited effort in studying the use of polyurea for structural retrofit and stre...

(This article belongs to the Special Issue Mechanical Properties of Polymers and Composites)

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