6,223 Results Found

Multiple Sclerosis (MS) is a complex, lifelong disease. Its effects span across different areas of life and vary strongly. In Switzerland, there is an intense discussion on how to optimize quality of care and patient safety. Patients should be more i...

The treatment paradigm of multiple myeloma (MM) has shifted in the past years, as continuous therapy is becoming the standard of care for both newly diagnosed and relapsed patients. Although it is indisputable that continuous therapy has added a grea...

Achieving and maintaining a high quality of life following the diagnosis of chronic illness has a positive impact on the experience of illness, including delayed disease progression and fewer relapses. Time perspective has shown promising relationshi...

There are multiple technological ways to identify humans and verify claimed identities. The dataset presented herein facilitates work on hard and soft biometric human identification and identity verification. It is comprised of full-body images of mu...

Dealing with paediatric-onset multiple sclerosis is particularly challenging for the young patients and their families, due to its unpredictable symptoms and uncertain outcome. This review aimed at synthesising the qualitative evidence regarding the...

Broiler sounds can provide feedback on their own body condition, to a certain extent. Aiming at the noise in the sound signals collected in broiler farms, research on evaluating the filtering methods for broiler sound signals from multiple perspectiv...

This perspective article gathers the latest developments in mathematical and computational oncology tools that exploit network approaches for the mathematical modelling, analysis, and simulation of cancer development and therapy design. It instigates...

The uncertainty assessment of urban hydrological models is important for understanding the reliability of the simulated results. To satisfy the demand for urban flood management, we assessed the uncertainty of urban hydrological models from a multipl...

Background: T-cell redirecting therapies (TCRTs), including CAR T-cell therapies and bispecific antibodies, have transformed treatment for relapsed/refractory multiple myeloma (MM), yet real-world adoption remains limited by awareness and access barr...

Substance abuse has been a thorny public health concern throughout human history. Manifestly, prevention and treatment are the two main strategies commonly adopted to tackle the problem of substance abuse. They are in fact cross-disciplinary, and the...

Introduction: Rehabilitation practices that adopt a strengths-based perspective are known as transdisciplinary evidence-based practices. However, little is known about whether and how such a perspective is experienced by people living with a neurolog...

The growth of online health communities and socially generated health-related content has the potential to provide considerable value for patients and healthcare providers alike. For example, members of the public can acquire medical knowledge and in...

Using the term of progressive multiple sclerosis (PMS), we considered a combined population of persons with secondary progressive MS (SPMS) and primary progressive MS (PPMS). These forms of MS cannot be challenged with efficacy by the licensed therap...

Background: Validated patient- and caregiver-reported outcome (PRO and CRO) questionnaires are widely used to assess quality of life (QoL) in multiple myeloma (MM). However, most were developed before recent therapeutic advances that have modified di...

A successful urban renewal policy, process, and project implementation should advocate sustainable development from economic, social, and environmental perspectives. As different stakeholders have different interests and insights into the importance...

It is vital to understand what kind of processes for learning that Geovisual Analytics creates, as certain activities and conditions are produced when employing Geovisual Anlytic tools in education. To understand learning processes created by Geovisu...

This paper challenges the World Religion Paradigm (WRP) dominating religious studies, advocating for a decolonial approach that focuses on diverse and often marginalized religious expressions. The approach that prioritizes world religions over the ri...

Identifying ecosystem service (ES) trade-offs and synergies (ESTSs) and their effects provides a critical scientific basis for ecological management. However, the effects of ESTSs are not always direct. To compensate for the limited research on the m...

Objective: The perspective applied in Health Technology Assessment (HTA) has recently been presented as a central methodological debate in HTA. Beyond expected effects on patients’ health and quality of life, health technologies can affect broa...

The act of decolonizing knowledge systems involves recovering and renewing traditional, non-commodified cultural patterns, such as the sustenance of intergenerational relationships and traditional practices. A decline in beaver harvesting, which was...

Nobel Laureate Markowitz originates portfolio selection as the birth of modern finance. Nobel Laureate Sharpe implements portfolio selection and originates capital asset pricing models. Nobel Laureate Fama also implements portfolio selection and orig...

Hospitals have valuable resources but are have facedsignificant changes over recentdecades. The adoption of principles that drive the strategic development of business models as innovation is imperative in these institutions. This research study aims...

High-tech SMEs are the new drivers of economic growth and innovation development. The complex and turbulent operating environment of the volatility, uncertainty, complexity, and ambiguity (VUCA) era poses a serious threat to high-tech SME sustainabil...

The environmental effects of green finance policies involve complex systemic interactions across multiple levels, yet existing studies often adopt fragmented analytical approaches. Drawing on the multi-level perspective (MLP), this study conceptualiz...

Today, the digital economy has pursued the required social and economic development, and enterprises can achieve green transition and long-term sustainability by relying on the digital platform ecosystem. However, the development of the digital econo...

Policies and programs of entrepreneurship education in higher education have shown proven effectiveness in fostering entrepreneurial intention, but there is limited evidence regarding their contribution to the effective success of business projects....

The article “Multiple Chemical Sensitivity: A Clinical Perspective”, published in Brain Sciences, suggests that multiple chemical sensitivity (MCS) is primarily a psychogenic disorder, rooted in unresolved emotional trauma and stress resp...

The dairy sector is in a systemic lock-in due to reinforcing cycles. This qualitative study, based on 13 in-depth interviews with frontrunning dairy farmers and additional observations, challenges this impression by looking at the sustainable busines...

Background/Objectives: Globally, multiple sclerosis (MS) management is associated with substantial economic burden, but its impact in Saudi Arabia has not been fully quantified. The aim of this study was to estimate the direct medical costs of MS in...

The identity of community residents is the basis for passing on the GIAHS (globally important agricultural heritage system) and promoting the sustainable development of heritage sites. However, there is a lack of discussion in the existent literature...

Multiple sclerosis (MS) is the inflammatory demyelinating and neurodegenerative disease of the central nervous system (CNS) that affects approximately 2.8 million people worldwide. In the last decade, a new era was heralded in by a new phenotypic cla...

Objective: The etiology of multiple chemical sensitivity (MCS) is still debated, which is an obstacle to assessing treatment options. An analysis of the scientific literature combined with the clinical experience can suggest some avenues. Methods: Th...

Jobs–housing imbalance is a hot topic in urban study and has obtained many results. However, little research has overcome the limits of administrative boundaries in job accessibility measurement and considered differences in job accessibility w...

Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease that is associated with multiple environmental factors. Among suspected susceptibility events, studies have questioned the potential role of overt viral...

Background: Medullary thyroid carcinoma (MTC), the third most frequent histological type of thyroid malignancy, may be found isolated or as part of multiple endocrine neoplasia type 2 (MEN2). One particular subtype of this autosomal dominant-transmit...

Background/Objectives: Multiple sclerosis (MS) is a chronic, progressive neurological disease with profound effects on physical functionality, psychosocial adaptation, and quality of life. This study aims to examine the perceptions, experiences, and...

Multiple sclerosis (MS) is a chronic, immune-mediated neurological disorder characterized by inflammation, demyelination, and progressive neurodegeneration. While genetic susceptibility contributes to disease risk, a growing body of evidence highligh...

Parametric design is a versatile decision-making methodology that allows multi-criteria optimization. However, it is not as common for addressing aspects such as the cultural heritage of a given community. In this context, qualitative research propos...

Green and high-efficiency water resource utilization patterns hold paramount importance in promoting sustainable economic and social development, as well as in attaining the goal of carbon neutrality. Most research on water utilization efficiency hav...

Stem cells have extensive proliferative potential and the ability to differentiate into one or more mature cell types. The mechanisms by which stem cells accomplish self-renewal provide fundamental insight into the origin and design of multicellular...

Multiple myeloma (MM) is a complex hematological malignancy characterized by abnormal proliferation of malignant plasma cells (PCs) within a permissive bone marrow microenvironment. The pathogenesis of MM is unequivocally linked to the acquisition of...

The Qinghai-Tibetan Plateau (QTP) is a global center of cold and dry, where the most extensive fragile alpine vegetation exists. Quantitative analysis of drought event characteristics and vegetation response to drought on the QTP is indispensable for...

A picture is a powerful and convenient medium for inducing the illusion that one perceives a three-dimensional scene. The relative invariance of picture perception across viewing positions has aroused the interest of painters, photographers, and visu...

Resilience research includes multiple definitions, concepts, perspectives, and applications across a broad range of academic disciplines. While experts, policy-makers, and practitioners assert that resilience requires holism, what is considered holis...

Insulin has pleiotropic effects, and is of importance both as a key regulator of glucose metabolism and as a growth factor [...]

The natural forest protection and restoration (NFPR) system is imperfect due to contradictions between the objectives of natural forest protection and the reality of situations, outdated cultivation concepts, conflicting interests among participating...

This study explores longitudinal influences of various factors on Black parents’ involvement in their children’s education. Guided by Hoover-Dempsey & Sandler’s Model of Parent Involvement, this research examines whether parents...

Multiple myeloma (MM) is an incurable plasma cell malignancy. In the context of the current standard of care therapies in Canada, outcomes among patients with relapsed/refractory multiple myeloma (RRMM), particularly those with triple-class (or more)...

Forest ecosystems are increasingly facing challenges related to overexploitation and climate and land-use change, thereby posing a threat to the myriad benefits they provide. Forest management is the only tool for ensuring that adaptation, mitigation...

Background: Multiple System Atrophy (MSA) is a rapidly progressing neurodegenerative movement disorder characterized by autonomic failure, parkinsonism, and cerebellar ataxia. While its non-motor symptoms are well-documented, personality features in...