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Special Issue "Advances in Mechanisms, Diagnosis and Therapy of Multiple Sclerosis and Other Demyelinating Diseases"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (15 November 2022) | Viewed by 11050
Special Issue Editors
Interests: neurology; multiple sclerosis; neuroimmunology; risk factors; therapy
Interests: multiple sclerosis; neuroimmunology; biogen animes
Special Issue Information
Multiple sclerosis (MS) and other demyelinating diseases (including NOMSD) are chronic autoimmune and neurodegenerative diseases of the central nervous system (CNS) in which inflammation, demyelination, and axonal degeneration lead to the fast progression of neurological disability in young adults. MS is a relatively common disease; its prevalence has increased substantially due to not only improved diagnostics and patient survival but also to the rise of MS incidence, which contributes to the high social and economic importance of the disease. MS is a complex disease that arises from the interplay between non-genetic and genetic risk factors. Environmental and genetic/epigenetic factors that influence on MS incidence are still under investigation, as well as the molecular and cell pathogenesis of the demyelinating and neurogenerative process in MS and NMOSD. The “inside-out” and “outside-in” hypotheses have been actively studied. In spite of real progress in MS and NOMSD immunomodulating therapy, there is no real possibility of tissue restoration and control on neurodegeneration. The mechanisms of the progression of the diseases are the main topic of numerous studies, and the results are sometimes controversial. Individual selection of therapy at different stages of the disease is very actual. We warmly welcome submissions, including original papers and reviews, on these widely discussed topics.
Prof. Dr. Alexey Boyko
Dr. Melnikov Mikhail
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- multiple sclerosis (MS)
- neuro-opticomyelitis optica spectrum diseases (NOMSDs)
- risk factors
- mechanism-based pathogenesis
- disease-modifying therapy (DMT)