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  • Article
  • Open Access
37 Citations
5,392 Views
22 Pages

Ascophyllum nodosum Based Extracts Counteract Salinity Stress in Tomato by Remodeling Leaf Nitrogen Metabolism

  • Emilia Dell’Aversana,
  • Valerio Cirillo,
  • Michael James Van Oosten,
  • Emilio Di Stasio,
  • Katya Saiano,
  • Pasqualina Woodrow,
  • Loredana Filomena Ciarmiello,
  • Albino Maggio and
  • Petronia Carillo

21 May 2021

Biostimulants have rapidly and widely been adopted as growth enhancers and stress protectants in agriculture, however, due to the complex nature of these products, their mechanism of action is not clearly understood. By using two algal based commerci...

(This article belongs to the Special Issue Biostimulants as Regulators of Carbon and Nitrogen Metabolism in Plants)
  • Article
  • Open Access
3 Citations
1,952 Views
20 Pages

Amino Acid Profile of Must and Aromatic Potential of 30 Minor Grape Varieties Grown in Alcalá de Henares (Spain)

  • Francisco Emmanuel Espinosa-Roldán,
  • M. Esperanza Valdés Sánchez,
  • Raquel Pavo Rico,
  • Daniel Moreno Cardona,
  • Fernando Martínez de Toda and
  • Gregorio Muñoz-Organero

30 April 2025

Amino acid composition and nitrogen quantification in grape must are of great importance given their usefulness for varietal characterization, influence on fermentation processes and identification of the aromatic potential of musts. The objective of...

(This article belongs to the Special Issue Sustainable Viticulture and Winemaking: Adapting to a Changing Climate)
  • Article
  • Open Access
13 Citations
6,149 Views
15 Pages

Hydrophobic Amino Acids as Universal Elements of Protein-Induced DNA Structure Deformation

  • Kateřina Faltejsková,
  • David Jakubec and
  • Jiří Vondrášek

Interaction with the DNA minor groove is a significant contributor to specific sequence recognition in selected families of DNA-binding proteins. Based on a statistical analysis of 3D structures of protein–DNA complexes, we propose that distort...

(This article belongs to the Collection Feature Papers in Molecular Biophysics)
  • Article
  • Open Access
1 Citations
2,179 Views
17 Pages

Digestibility, Energy Value, and Performance of Lemna minor as a Novel Protein Source in Broiler Chicken Diets

  • Johannes Niermeyer,
  • Johannes Demann,
  • Finn Petersen,
  • Georg Dusel,
  • Reindert Devlamynck,
  • Andreas Ulbrich,
  • Hans-Werner Olfs and
  • Heiner Westendarp

6 March 2026

Global population growth is expected to increase poultry meat demand, intensifying the need for sustainable protein sources. Soybean meal, the primary protein feed for poultry, has negative associations with deforestation and long transport distances...

(This article belongs to the Collection Poultry Nutrition)
  • Article
  • Open Access
1 Citations
1,594 Views
24 Pages

SOS1 is a Na+/H+ antiporter found in the plant membrane of Arabidopsis thaliana and serves as a major transporter that extrudes Na+ across the plasma membrane of cells in exchange for intracellular H+. The first 450 amino acids comprise the membrane...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
31 Citations
5,001 Views
14 Pages

Two Highly Similar Chitinases from Marine Vibrio Species have Different Enzymatic Properties

  • Xinxin He,
  • Min Yu,
  • Yanhong Wu,
  • Lingman Ran,
  • Weizhi Liu and
  • Xiao-Hua Zhang

27 February 2020

Chitinase, as one of the most important extracellular enzymes in the marine environment, has great ecological and applied values. In this study, two chitinases (Chi1557 and Chi4668) with 97.33% amino acid sequences identity were individually found in...

  • Article
  • Open Access
4 Citations
2,645 Views
13 Pages

A Comparison of White Muscle Quality in Grass Carp Ctenopharyngodon idellus Fed with Commercial Feeds and Barley Malt

  • Chongjiang Hu,
  • Zheng Huang,
  • Hongkang Liu,
  • Dingrui Mo,
  • Peng Fu,
  • Haiyan Guo,
  • Wei Jiang,
  • Yong Xie and
  • Yongjun Chen

18 April 2025

This study was the first report regarding the application of barley malt (BM) for diets of aquaculture species. Triplicate groups of grass carp Ctenopharyngodon idellus with an initial size of about 1.2 kg were selected and fed with either BM or comm...

(This article belongs to the Special Issue Growth, Metabolism, and Flesh Quality in Aquaculture Nutrition)
  • Article
  • Open Access
23 Citations
8,003 Views
16 Pages

Isolation and Synthesis of Laxaphycin B-Type Peptides: A Case Study and Clues to Their Biosynthesis

  • Louis Bornancin,
  • France Boyaud,
  • Zahia Mahiout,
  • Isabelle Bonnard,
  • Suzanne C. Mills,
  • Bernard Banaigs and
  • Nicolas Inguimbert

5 December 2015

The laxaphyci’s B family constitutes a group of five related cyclic lipopeptides isolated from diverse cyanobacteria from all around the world. This group shares a typical structure of 12 amino acids from the l and d series, some of them hydroxylate...

(This article belongs to the Special Issue Compounds from Cyanobacteria)
  • Article
  • Open Access
9 Citations
4,099 Views
16 Pages

7 November 2022

Analytical scale chemical/cultivation profiling prioritized the Australian marine-derived fungus Aspergillus noonimiae CMB-M0339. Subsequent investigation permitted isolation of noonindoles A–F (5–10) and detection of eight minor analogue...

(This article belongs to the Special Issue Bioactive Secondary Metabolites of Marine Fungi)
  • Article
  • Open Access
4 Citations
2,571 Views
14 Pages

A Novel Isolate of Bean Common Mosaic Virus Isolated from Crownvetch (Securigera varia L. Lassen)

  • Daniel Mihálik,
  • Simona Grešíková,
  • Richard Hančinský,
  • Pavel Cejnar,
  • Michaela Havrlentová and
  • Ján Kraic

22 June 2023

Bean common mosaic virus from the genus Potyvirus has a wide range of hosts and a very negative impact on cultivated crops from the genus Phaseolus. The risk of viral infection of economically important crops increases even if the carriers of the vir...

(This article belongs to the Section Pest and Disease Management)
  • Article
  • Open Access
2 Citations
4,315 Views
16 Pages

Dietary Alaska Pollack Protein Induces Acute Skeletal Muscle Hypertrophy in Rats, Regardless of Specific Amino Acid and Amino Acid Balance of Diet

  • Kenji Uchida,
  • Mina Fujitani,
  • Takafumi Mizushige,
  • Kohsuke Hayamizu,
  • Yuma Hara,
  • Mariko Sawai,
  • Sachi Utsunomiya,
  • Ryota Uehigashi,
  • Shinji Okada and
  • Taro Kishida

In previous studies, Alaska pollack protein intake induced acute and sustainable skeletal muscle hypertrophy in rats. The present study used 5-week-old male Sprague–Dawley rats to investigate whether a specific amino acid or amino acid composit...

  • Article
  • Open Access
76 Citations
6,135 Views
15 Pages

The Effect of Amino Acids on Production of SCFA and bCFA by Members of the Porcine Colonic Microbiota

  • Pieter Van den Abbeele,
  • Jonas Ghyselinck,
  • Massimo Marzorati,
  • Anna-Maria Koch,
  • William Lambert,
  • Joris Michiels and
  • Tristan Chalvon-Demersay

Functional amino acids supplementation to farm animals is considered to not only be beneficial by regulating intestinal barrier, oxidative stress, and immunity, but potentially also by impacting the gut microbiota. The impact of amino acids on a pigl...

(This article belongs to the Special Issue Gut Microbiota and Nutrients)
  • Article
  • Open Access
10 Citations
3,550 Views
12 Pages

Concentrations of Plasma Amino Acids and Neurotransmitters in Participants with Functional Gut Disorders and Healthy Controls

  • Shanalee C. James,
  • Karl Fraser,
  • Janine Cooney,
  • Catrin S. Günther,
  • Wayne Young,
  • Richard B. Gearry,
  • Phoebe E. Heenan,
  • Tania Trower,
  • Jacqueline I. Keenan and
  • Nicole C. Roy
  • + 2 authors

20 February 2023

Amino acids are important in several biochemical pathways as precursors to neurotransmitters which impact biological processes previously linked to functional gastrointestinal disorders (FGIDs). Dietary protein consumption, metabolic host processes,...

(This article belongs to the Section Nutrition and Metabolism)
  • Article
  • Open Access
5 Citations
3,528 Views
14 Pages

Amino Acids Reduce Mild Steel Corrosion in Used Cooking Oils

  • Nina Bruun,
  • Juho Lehmusto,
  • Fiseha Tesfaye,
  • Jarl Hemming and
  • Leena Hupa

24 March 2022

In this study, we tested several amino acids as eco-friendly inhibitors against corrosion of mild steel by used cooking oils (UCOs). The corrosion inhibition was studied by immersing mild steel rods in the UCOs and reference fresh rapeseed and olive...

(This article belongs to the Section Energy Sustainability)
  • Article
  • Open Access
3 Citations
3,053 Views
12 Pages

Simultaneous SERS Detection of Multiple Amino Acids Using ZIF-8@AuNPs as Substrate: Classified with 1D Convolutional Neural Network

  • Mengping Huang,
  • Shuai Ma,
  • Jinrong He,
  • Wei Xue,
  • Xueyan Hou,
  • Yuqi Zhang,
  • Xiaofeng Liu,
  • Heping Bai and
  • Ran Li

4 March 2024

Amino acids found in minor coarse cereals are essential for human growth and development and play a crucial role in efficient and rapid quantitative detection. Surface-enhanced Raman spectroscopy (SERS) enables nondestructive, efficient, and rapid sa...

(This article belongs to the Section Food Science and Technology)
  • Article
  • Open Access
17 Citations
7,049 Views
16 Pages

Nutritional Composition and Bioactive Profiles of Farmed and Wild Watermeal (Wolffia globosa)

  • Nidthaya Seephua,
  • Parinya Boonarsa,
  • Hua Li,
  • Pornpisanu Thammapat and
  • Sirithon Siriamornpun

21 May 2025

This study assessed the nutritional composition, bioactive compounds, phytosterol content, amino acids, and fatty acid profiles of watermeal cultivated under farm conditions (WF1) and harvested from natural environments (WF2 and WF3). WF1 exhibited t...

(This article belongs to the Special Issue Bioactive Compounds in Food: From Molecule to Biological Function)
  • Article
  • Open Access
999 Views
17 Pages

Proximate Composition, Amino Acid Content and Antioxidant Activity of Different Potato Varieties from the Matese Plateau (Southern Italy)

  • Nicola Landi,
  • Sara Ragucci,
  • Sofia Del Gaudio,
  • Maria Giuseppina Campanile,
  • Robina Khan,
  • Maria D’Angelo,
  • Stefania Papa,
  • Enrica De Falco and
  • Antimo Di Maro

8 May 2026

Here, the proximate composition, total amino acid content and antioxidant activity of Agria, Désirée and Kennebec potato varieties cultivated on the Matese plateau (Campania region, Southern Italy) were evaluated. Significant difference...

(This article belongs to the Section Food Physics and (Bio)Chemistry)
  • Brief Report
  • Open Access
18 Citations
6,928 Views
8 Pages

Exploratory Study on the Foliar Incorporation and Stability of Isotopically Labeled Amino Acids Applied to Turfgrass

  • Rachel M. McCoy,
  • George W. Meyer,
  • David Rhodes,
  • George C. Murray,
  • Thomas G. Sors and
  • Joshua R. Widhalm

5 March 2020

There is increasing interest in the use of amino acid-based biostimulant products due to their reported abilities to improve a number of quality characteristics in a variety of specialty crops. However, when it comes to the foliar application of amin...

(This article belongs to the Special Issue Toward a Sustainable Agriculture Through Plant Biostimulants: From Experimental Data to Practical Applications)
  • Article
  • Open Access
10 Citations
5,834 Views
13 Pages

Effect of Sex and Age on Nutritional Content in Wild Axis Deer (Axis axis Erx.) Meat

  • Nikolina Kelava Ugarković,
  • Miljenko Konjačić,
  • Zvonimir Prpić,
  • Kristijan Tomljanović and
  • Damir Ugarković

2 September 2020

The aim of this study is to examine the effect of sex and age on proximate chemical, fatty acid, amino acid and mineral content of axis deer (Axis axis Erx.) meat. Sixteen (n = 16) animals were hunt-harvested and assigned to groups according sex and...

(This article belongs to the Section Wildlife)
  • Article
  • Open Access
4 Citations
3,390 Views
13 Pages

2 September 2022

Asymmetric Michael additions of carbonyl compounds to N-substituted maleimides are among the most convenient reactions to prepare optically pure succinimide building blocks. Although a few β-amino acids were found to be highly efficient organoca...

(This article belongs to the Special Issue Catalysis in Heterocyclic and Organometallic Synthesis II)
  • Article
  • Open Access
15 Citations
4,076 Views
16 Pages

Nutrient Constituents, Bioactive Phytochemicals, and Antioxidant Properties of Service Tree (Sorbus domestica L.) Fruits

  • Manol Ognyanov,
  • Petko Denev,
  • Nadezhda Petkova,
  • Zhana Petkova,
  • Magdalena Stoyanova,
  • Peter Zhelev,
  • Georgi Matev,
  • Desislava Teneva and
  • Yordan Georgiev

13 July 2022

The current study aimed to determine the major and minor nutritional constituents of Sorbus domestica L. fruits. It was revealed that palmitic acid was the most commonly occurring saturated fatty acid, while linoleic acid represented the major polyun...

(This article belongs to the Special Issue 10th Anniversary of Plants—Recent Advances and Perspectives)
  • Article
  • Open Access
849 Views
15 Pages

13 February 2026

This study constructed a bioinformatics prediction algorithm for human enterovirus uncoating receptors based on amino acid sequences and physicochemical properties. Based on the availability of uncoating receptor information and three-dimensional (3D...

(This article belongs to the Special Issue Coxsackieviruses, Polioviruses and Associated Diseases (Second Edition))
  • Article
  • Open Access
1 Citations
16,761 Views
7 Pages

Synthesis of 9,9′-[1,2-Ethanediylbis(oxymethylene)]bis-2-amino-1,9-dihydro-6H-purin-6-one, an Impurity of Acyclovir

  • Rosa M. Suárez,
  • Maria Paz Matía,
  • José Luis Novella,
  • Andres Molina,
  • Antonio Cosme,
  • Juan José Vaquero and
  • Julio Alvarez-Builla

25 July 2012

The synthesis of 9,9'-[1,2-ethanediylbis(oxymethylene)]bis-2-amino-1,9-dihydro-6H-purin-6-one, a minor impurity of acyclovir, is described. Starting with commercial N-(9-acetyl-6-oxo-1H-purin-2-yl)acetamide, the process uses an acid catalysed phase t...

(This article belongs to the Section Organic Chemistry)
  • Article
  • Open Access
32 Citations
8,333 Views
14 Pages

8 August 2018

Effects of proteolytic (Neutrase, Bacillus subtilis-originate, 0.20 (P1) and 0.40 g 100 L−1 (P2)) and lipolytic (Piccantase A, Mucor miehei-originated, 0.05 (L1) and 0.10 g 100 L−1 (L2)) enzyme supplementations to cheese milk on lipolysis...

(This article belongs to the Special Issue Selected Papers from International Conference on Raw Material to Processed Foods)
  • Article
  • Open Access
12 Citations
4,784 Views
12 Pages

7 February 2021

Olive oil has been favored as high-quality edible oil because it contains balanced fatty acids (FAs) and high levels of minor components. The contents of FAs and minor components are variable in olive fruits of different color at harvest time, which...

(This article belongs to the Special Issue Extraction, Characterization and Biological Activity of Food Bioactive Compounds)
  • Article
  • Open Access
23 Citations
15,924 Views
22 Pages

HIV-1 Subtype C Phylodynamics in the Global Epidemic

  • Vlad Novitsky,
  • Rui Wang,
  • Stephen Lagakos and
  • Max Essex

7 January 2010

The diversity of HIV-1 and its propensity to generate escape mutants present fundamental challenges to control efforts, including HIV vaccine design. Intra-host diversification of HIV is determined by immune responses elicited by an HIV-infected indi...

(This article belongs to the Special Issue AIDS Vaccine)
  • Article
  • Open Access
52 Citations
8,286 Views
11 Pages

The Role of H2O2-Scavenging Enzymes (Ascorbate Peroxidase and Catalase) in the Tolerance of Lemna minor to Antibiotics: Implications for Phytoremediation

  • Marcelo Pedrosa Gomes,
  • Rafael Shinji Akiyama Kitamura,
  • Raizza Zorman Marques,
  • Marcello Locatelli Barbato and
  • Marcel Zámocký

13 January 2022

We investigated the individual and combined contributions of two distinct heme proteins namely, ascorbate peroxidase (APX) and catalase (CAT) on the tolerance of Lemna minor plants to antibiotics. For our investigation, we used specific inhibitors of...

(This article belongs to the Special Issue The Role of Peroxidases and Catalases in Photosynthetic and Non–photosynthetic Eukaryotes)
  • Article
  • Open Access
748 Views
14 Pages

1 July 2026

Background: Cancer-related cachexia is primarily characterized by systemic inflammation and progressive muscle wasting, which is why a high-protein diet (from 1.2 to 1.5 g/kg/day) is commonly recommended. However, concerns remain that an excessive su...

(This article belongs to the Special Issue Enteral, Parenteral Nutrition, and Exercise in Supportive Cancer Treatment)
  • Review
  • Open Access
148 Citations
23,599 Views
13 Pages

Impact of Wort Amino Acids on Beer Flavour: A Review

  • Inês M. Ferreira and
  • Luís F. Guido

The process by which beer is brewed has not changed significantly since its discovery thousands of years ago. Grain is malted, dried, crushed and mixed with hot water to produce wort. Yeast is added to the sweet, viscous wort, after which fermentatio...

(This article belongs to the Special Issue Brewing & Distilling)
  • Article
  • Open Access
15 Citations
3,726 Views
14 Pages

An Untargeted Metabolomics Approach to Study the Variation between Wild and Cultivated Soybeans

  • Fakir Shahidullah Tareq,
  • Raghavendhar R. Kotha,
  • Savithiry Natarajan,
  • Jianghao Sun and
  • Devanand L. Luthria

19 July 2023

The differential metabolite profiles of four wild and ten cultivated soybeans genotypes were explored using an untargeted metabolomics approach. Ground soybean seed samples were extracted with methanol and water, and metabolic features were obtained...

(This article belongs to the Section Food Chemistry)
  • Article
  • Open Access
7 Citations
5,268 Views
15 Pages

New Insights into Red and White Quinoa Protein Isolates: Nutritional, Functional, Thermal Properties

  • Khalid A. Alsaleem,
  • Rofida F. Moftah and
  • Mennatallah M. A. El-Geddawy

9 December 2024

Quinoa (Chenopodium quinoa Willd.) seeds, renowned for their nutritional richness and balanced amino acid profile, offer promising potential as food ingredients. This study focused on extracting and characterizing the protein isolates from red and wh...

(This article belongs to the Special Issue Separation and Extraction Techniques in Food Processing and Analysis)
  • Article
  • Open Access
26 Citations
4,845 Views
14 Pages

12 November 2021

The biotrophic fungal pathogen Ustilago maydis causes common smut in maize, forming tumors on all aerial organs, especially on reproductive organs, leading to significant reduction in yield and quality defects. Resistance to U. maydis is thought to b...

(This article belongs to the Special Issue Maize Functional Genomics, Genetics and Breeding)
  • Case Report
  • Open Access
12 Citations
9,413 Views
18 Pages

Compound Analysis of Jing Liqueur and nrf2 Activation by Jing Liqueur—One of the Most Popular Beverages in China

  • You-Sheng Cai,
  • Jian Xu,
  • Mosi Chen,
  • Daoqing Wang,
  • Yuejun Yang,
  • Arulmani Manavalan,
  • Xiaohua Wu,
  • Yuancai Liu and
  • Shugeng Cao

31 December 2019

The aim of this study is to identify the minor compounds in Jing liqueur, determine the concentration of metals, amino acids, and polysaccharides, and evaluate their Nrf2 activity and cytotoxicity. Jing liqueur that contains Chinese medicine is one o...

  • Article
  • Open Access
51 Citations
10,543 Views
16 Pages

Catharanthus roseus (C. roseus) and Vinca minor (V. minor) are two common important medical plants belonging to the family Apocynaceae. In this study, we used non-targeted GC-MS and targeted LC-MS metabolomics to dissect the metabolic profile of two...

  • Short Note
  • Open Access
14 Citations
8,906 Views
10 Pages

Minor Role of Mitochondrial Respiration for Fatty-Acid Induced Insulin Secretion

  • Nadja Schulz,
  • Oliver Kluth,
  • Martin Jastroch and
  • Annette Schürmann

16 September 2013

An appropriate insulin secretion by pancreatic beta-cells is necessary to maintain glucose homeostasis. A rise in plasma glucose leads to increased metabolism and an elevated cytoplasmic ATP/ADP ratio that finally triggers insulin granule exocytosis....

(This article belongs to the Section Molecular Recognition)
  • Article
  • Open Access
27 Citations
6,394 Views
26 Pages

Agronomic and Environmental Performance of Lemnaminor Cultivated on Agricultural Wastewater Streams—A Practical Approach

  • Reindert Devlamynck,
  • Marcella Fernandes de Souza,
  • Evi Michels,
  • Ivona Sigurnjak,
  • Natalia Donoso,
  • Carl Coudron,
  • Jan Leenknegt,
  • Pieter Vermeir,
  • Mia Eeckhout and
  • Erik Meers

2 February 2021

This study investigated the potential of Lemna minor to valorise agricultural wastewater in protein-rich feed material in order to meet the growing demand for animal feed protein and reduce the excess of nutrients in certain European regions. For thi...

(This article belongs to the Special Issue Environmental Impact of Livestock Production and Mitigation Strategies)
  • Article
  • Open Access
15 Citations
2,381 Views
18 Pages

The Influence of Fermentation Technology on the Functional and Sensory Properties of Hemp Bread

  • Stanisław Kowalski,
  • Anna Mikulec,
  • Dorota Litwinek,
  • Barbara Mickowska,
  • Magdalena Skotnicka,
  • Joanna Oracz,
  • Kaja Karwowska,
  • Anna Wywrocka-Gurgul,
  • Renata Sabat and
  • Anna Platta

19 November 2024

In this work, the type of fermentation and baking technology used to make hemp bread was investigated. The physicochemical composition of flour and bread, the protein nutritional quality, fatty acids profile, texture, consumer acceptance, analysis of...

(This article belongs to the Special Issue The Impact of Advances in Fermentation Processes on the Chemical Composition of the Final Product, 2nd Edition)
  • Article
  • Open Access
12 Citations
4,050 Views
12 Pages

15 April 2021

Derivatization of amino acids by 2 M HCl/CH3OH (60 min, 80 °C) followed by derivatization of the intermediate methyl esters with pentafluoropropionic anhydride (PFPA) in ethyl acetate (30 min, 65 °C) is a useful two-step derivatization procedure (pro...

(This article belongs to the Special Issue Derivatization in Analytical Chemistry)
  • Article
  • Open Access
8 Citations
4,156 Views
14 Pages

31 March 2022

Mycosporine-like amino acids are a prevalent form of photoprotection in micro- and macro-organisms. Using a combination of natural product extraction/purification and femtosecond transient absorption spectroscopy, we studied the relaxation pathway fo...

(This article belongs to the Special Issue Rotational and Vibrational Probes of Biomolecular Structure and Dynamics)
  • Article
  • Open Access
10 Citations
3,677 Views
13 Pages

Chimeric Investigations into the Diamide Binding Site on the Lepidopteran Ryanodine Receptor

  • Ewan Richardson,
  • Bartek J. Troczka,
  • Oliver Gutbrod,
  • Ulrich Ebbinghaus-Kintscher,
  • Martin S. Williamson,
  • Christopher H. George,
  • Ralf Nauen and
  • Thomas G. Emyr Davies

2 December 2021

Alterations to amino acid residues G4946 and I4790, associated with resistance to diamide insecticides, suggests a location of diamide interaction within the pVSD voltage sensor-like domain of the insect ryanodine receptor (RyR). To further delineate...

(This article belongs to the Section Molecular Toxicology)
  • Article
  • Open Access
26 Citations
6,366 Views
22 Pages

SARS-CoV-2 Mutant Spectra at Different Depth Levels Reveal an Overwhelming Abundance of Low Frequency Mutations

  • Brenda Martínez-González,
  • María Eugenia Soria,
  • Lucía Vázquez-Sirvent,
  • Cristina Ferrer-Orta,
  • Rebeca Lobo-Vega,
  • Pablo Mínguez,
  • Lorena de la Fuente,
  • Carlos Llorens,
  • Beatriz Soriano and
  • Celia Perales
  • + 22 authors

Populations of RNA viruses are composed of complex and dynamic mixtures of variant genomes that are termed mutant spectra or mutant clouds. This applies also to SARS-CoV-2, and mutations that are detected at low frequency in an infected individual ca...

(This article belongs to the Collection SARS-CoV-2 Infection and COVID-19 Disease)
  • Article
  • Open Access
958 Views
17 Pages

5 March 2026

The growing demand for sustainable protein alternatives has increased interest in underutilized plant biomasses with high nutritional potential. This study investigated the conversion efficiency of alfalfa (Medicago sativa L.) and duckweed (Lemna min...

(This article belongs to the Section Food Physics and (Bio)Chemistry)
  • Article
  • Open Access
47 Citations
7,717 Views
20 Pages

Bioactivity of Biomass and Crude Exopolysaccharides Obtained by Controlled Submerged Cultivation of Medicinal Mushroom Trametes versicolor

  • Galena Angelova,
  • Mariya Brazkova,
  • Dasha Mihaylova,
  • Anton Slavov,
  • Nadejda Petkova,
  • Denica Blazheva,
  • Ivelina Deseva,
  • Irina Gotova,
  • Zhechko Dimitrov and
  • Albert Krastanov

17 July 2022

The aim of this study is to characterize the bioactivity of mycelial biomass and crude exopolysaccharides (EPS) produced by Trametes versicolor NBIMCC 8939 and to reveal its nutraceutical potential. The EPS (1.58 g/L) were isolated from a culture bro...

(This article belongs to the Special Issue New Perspectives on Bioactive Compounds in Mushrooms)
  • Article
  • Open Access
41 Citations
6,537 Views
17 Pages

27 October 2018

Sclerotinia minor is a phytopathogenic fungus causing sclerotinia blight on many economically important crops. Here, we have characterized the biological and molecular properties of a novel endornavirus, Sclerotinia minor endornavirus 1 (SmEV1), isol...

(This article belongs to the Special Issue Mycoviruses)
  • Article
  • Open Access
4,488 Views
22 Pages

Effects of Foliar and Root Application of Different Amino Acids on Mini-Watermelon

  • Huiyu Wang,
  • Hongxu Wang,
  • Jing Zong,
  • Jinghong Hao,
  • Jin Xu,
  • Mingshan Qu,
  • Ting Li and
  • Yingyan Han

Biostimulants, particularly single amino acids, can increase plant growth and crop quality, gaining significant attention. This study investigates the effects of 10 amino acids via root/foliar application on the growth, quality, taste, and volatile f...

(This article belongs to the Special Issue Effects of Biostimulants on Horticultural Crop Production)
  • Article
  • Open Access
10 Citations
3,925 Views
21 Pages

Systemic Metabolomic Profiles in Adult Patients with Bacterial Sepsis: Characterization of Patient Heterogeneity at the Time of Diagnosis

  • Knut Anders Mosevoll,
  • Bent Are Hansen,
  • Ingunn Margareetta Gundersen,
  • Håkon Reikvam,
  • Øyvind Bruserud,
  • Øystein Bruserud and
  • Øystein Wendelbo

24 January 2023

Sepsis is a dysregulated host response to infection that causes potentially life-threatening organ dysfunction. We investigated the serum metabolomic profile at hospital admission for patients with bacterial sepsis. The study included 60 patients; 35...

(This article belongs to the Special Issue Proteomics and Metabolomics Biomarkers in Different Diseases)
  • Article
  • Open Access
12 Citations
4,429 Views
10 Pages

Hepatitis E Virus Shows More Genomic Alterations in Cell Culture than In Vivo

  • Gulce Sari,
  • Martijn D.B. van de Garde,
  • Anne van Schoonhoven,
  • Jolanda J.C. Voermans,
  • Annemiek A. van der Eijk,
  • Robert A. de Man,
  • Andre Boonstra,
  • Thomas Vanwolleghem and
  • Suzan D. Pas

22 November 2019

Hepatitis E Virus (HEV) mutations following ribavirin treatment have been associated with treatment non-response and viral persistence, but spontaneous occurring genomic variations have been less well characterized. We here set out to study the HEV g...

(This article belongs to the Special Issue Hepatitis E Virus (HEV) Infections)
  • Article
  • Open Access
4 Citations
1,581 Views
17 Pages

Caspofungin Reshapes the Extracellular Vesicles Metabolome of Candidozyma (Candida) auris, Altering Amino Acid and Nucleotide Metabolism

  • Vinicius Alves,
  • Claire V. Mulholland,
  • Daniel Zamith-Miranda,
  • Susana Frases,
  • Michael Berney and
  • Joshua D. Nosanchuk

21 February 2026

Candidozyma auris is an emerging multidrug-resistant fungal pathogen associated with severe invasive infections and high mortality, particularly in healthcare environments. Its rapid global expansion and resistance to multiple antifungal classes pose...

(This article belongs to the Special Issue Multidrug-Resistant Fungi: New Strategies for Diagnosis and Treatment—2nd Edition)
  • Article
  • Open Access
40 Citations
6,726 Views
25 Pages

4 March 2020

Honey is a natural pure food produced by honeybees from the nectar of various plants, and its chemical composition includes carbohydrates, water, and some minor compounds, which are very important for honey quality and authentication. Most of honey&r...

(This article belongs to the Section Chemical and Molecular Sciences)
  • Feature Paper
  • Article
  • Open Access
6 Citations
3,431 Views
20 Pages

15 July 2025

Yellow mealworm (Tenebrio molitor) meal is a promising sustainable protein for pet food, yet its effect on nutrient balance and granule texture is incompletely defined. Five dry dog food formulas containing 25%, 30%, 35%, 40%, and 45% of T. molitor m...

(This article belongs to the Special Issue Animal Health: Potential Benefits of Edible Insects)

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