Next Article in Journal
Impact of Chitosan on the Mechanical Stability of Soils
Next Article in Special Issue
Structural Properties of Phenylalanine-Based Dimers Revealed Using IR Action Spectroscopy
Previous Article in Journal
Synthesis and Hemostatic Activity of New Amide Derivatives
Previous Article in Special Issue
Rotational Spectrum and Conformational Analysis of Perillartine: Insights into the Structure–Sweetness Relationship
Article

Investigating the Ultrafast Dynamics and Long-Term Photostability of an Isomer Pair, Usujirene and Palythene, from the Mycosporine-like Amino Acid Family

1
Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK
2
Analytical Science Centre for Doctoral Training, Senate House, University of Warwick, Coventry CV4 7AL, UK
3
Warwick Integrative Synthetic Biology Centre, School of Life Sciences, University of Warwick, Coventry CV4 7AL, UK
*
Author to whom correspondence should be addressed.
Academic Editors: Maria Eugenia Sanz and Tersilla Virgili
Molecules 2022, 27(7), 2272; https://doi.org/10.3390/molecules27072272
Received: 2 March 2022 / Revised: 25 March 2022 / Accepted: 28 March 2022 / Published: 31 March 2022
Mycosporine-like amino acids are a prevalent form of photoprotection in micro- and macro-organisms. Using a combination of natural product extraction/purification and femtosecond transient absorption spectroscopy, we studied the relaxation pathway for a common mycosporine-like amino acid pair, usujirene and its geometric isomer palythene, in the first few nanoseconds following photoexcitation. Our studies show that the electronic excited state lifetimes of these molecules persist for only a few hundred femtoseconds before the excited state population is funneled through an energetically accessible conical intersection with subsequent vibrational energy transfer to the solvent. We found that a minor portion of the isomer pair did not recover to their original state within 3 ns after photoexcitation. We investigated the long-term photostability using continuous irradiation at a single wavelength and with a solar simulator to mimic a more real-life environment; high levels of photostability were observed in both experiments. Finally, we employed computational methods to elucidate the photochemical and photophysical properties of usujirene and palythene as well as to reconcile the photoprotective mechanism. View Full-Text
Keywords: mycosporine-like amino acids; usujirene; palythene; ultrafast spectroscopy; photophysics; photochemistry mycosporine-like amino acids; usujirene; palythene; ultrafast spectroscopy; photophysics; photochemistry
Show Figures

Figure 1

MDPI and ACS Style

Whittock, A.L.; Woolley, J.M.; Auckloo, N.; Corre, C.; Stavros, V.G. Investigating the Ultrafast Dynamics and Long-Term Photostability of an Isomer Pair, Usujirene and Palythene, from the Mycosporine-like Amino Acid Family. Molecules 2022, 27, 2272. https://doi.org/10.3390/molecules27072272

AMA Style

Whittock AL, Woolley JM, Auckloo N, Corre C, Stavros VG. Investigating the Ultrafast Dynamics and Long-Term Photostability of an Isomer Pair, Usujirene and Palythene, from the Mycosporine-like Amino Acid Family. Molecules. 2022; 27(7):2272. https://doi.org/10.3390/molecules27072272

Chicago/Turabian Style

Whittock, Abigail L., Jack M. Woolley, Nazia Auckloo, Christophe Corre, and Vasilios G. Stavros. 2022. "Investigating the Ultrafast Dynamics and Long-Term Photostability of an Isomer Pair, Usujirene and Palythene, from the Mycosporine-like Amino Acid Family" Molecules 27, no. 7: 2272. https://doi.org/10.3390/molecules27072272

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop