Transcription control plays a crucial role in establishing a unique gene expression signature for each of the hundreds of mammalian cell types. Though gene expression data have been widely used to infer cellular regulatory networks, existing methods...
Tight regulation of gene transcription is essential for normal development, tissue homeostasis, and disease-free survival. Enhancers are distal regulatory elements in the genome that provide specificity to gene expression programs and are frequently...
B-cell lymphomas and leukemias derive from B cells at various stages of maturation and are the 6th most common cancer-related cause of death. While the role of several oncogenes and tumor suppressors in the pathogenesis of B-cell neoplasms was establ...
Searching for natural products with antitumor and immune-enhancing activities is an important aspect of cancer research. Sargassum pallidum is an edible brown alga that has been used in Chinese traditional medicine for the treatment of tumors. Howeve...
Enhancement, control, and tuning of hydrolytic activity and specificity of lipases are major goals for the industry. Thermoalkaliphilic lipases from the I.5 family, with their native advantages such as high thermostability and tolerance to alkaline p...
The development of effective treatments against infectious diseases is an extensive and ongoing process due to the rapid adaptation of bacteria to antibiotic-based therapies. However, appropriately designed activity enhancers, including antibiotic de...
Enhanced catalysis for organic transformation is essential for the synthesis of high-value compounds. Atomic metal species recently emerged as highly effective catalysts for organic reactions with high activity and metal utilization. However, develop...
Lewy bodies are pathological characteristics of Lewy body dementia (LBD) and are composed of α-synuclein (α-Syn), which is mostly degraded via the ubiquitin–proteasome system. More importantly, 26S proteasomal activity decreases in the brain of LBD p...
Background and Objective: The dynamic assessment of disease activity during the follow-up of patients with Crohn’s disease (CD) remains a significant challenge. In this study, we aimed to identify the role of dynamic contrast-enhanced ultrasoun...
Adsorption of pollutants on activated carbon is an effective air pollution control technique. In this study, a strong and non-uniform electric field was applied over an activated carbon fiber cloth. The adsorption kinetic of several organic compounds...
Expansive soil poses significant challenges for engineering due to its susceptibility to swelling and shrinkage. This study aims to explore effective methods for improving its mechanical properties using single alkaline activators, single slag, and t...
Cardiac regenerative capacity varies widely among vertebrates. Zebrafish can robustly regenerate injured hearts and are excellent models to study the mechanisms of heart regeneration. Recent studies have shown that enhancers are able to respond to in...
Epilobium angustifolium L. is a popular medicinal plant found in many regions of the world. This plant contains small amounts of essential oil whose composition and properties have not been extensively investigated. There are few reports in the liter...
This research aimed to enhance the antibacterial activity of silver nanoparticles (AgNPs) synthesized from silver nitrate (AgNO3) using aloe vera extract. It was performed by means of incorporating AgNPs on an activated carbon nanoparticle (ACNPs) un...
Background: Strength-Duration (S-D) assessment is commonly used in clinics to examine the excitability of peripheral nerves and muscles. Yet, how changes in neuromuscular excitability relate to improved athletic and muscular performance in healthy su...
Renewable energy resources require energy storage techniques to curb problems with intermittency. One potential solution is the use of phase change materials (PCMs) in latent heat thermal energy storage (LHTES) systems. Despite the high energy storag...
Complex human activities consist of sequential, simple limb movements, acting as impulse responses from the motor system. In short-term human activity recognition (ST-HAR), the inherently brief observation window results in non-stationary signals and...
The Logical and Activity Learning for Enhanced Thinking Skills (LAL) method is an educational approach that fosters the development of critical thinking, problem-solving, and decision-making abilities in students using practical, experiential learnin...
Given the shortage of zinc resource, the low utilisation efficiency of secondary zinc resource, and the crucial problem that the synchronous dissolution of zinc from different mineral phases, an activation pretreatment method merged with calcium acti...
This meta-analysis assessed the impact of three induction methods on athletes’ jump and sprint performances. Experimental research on the acute effects of exercise intervention on the Post-Activation Performance Enhancement (PAPE) of jumping an...
In Poland—especially in the less developed eastern regions—the level of health-enhancing physical activity (HEPA) remains below the WHO recommendations, and its determinants are not yet fully understood. The study was conducted as part of...
Recently, selenium nanoparticles have been drawing attention worldwide, and it is crucial to increase the stability of nano-Se. Morinda officinalis polysaccharides (MOP) are the main active component in Morinda officinalis radix. However, their low a...
The aim was to identify if surface electromyography (sEMG) parameters are indicative of post-activation potentiation (PAP)/post-activation performance enhancement (PAPE), in terms of twitch potentiation and voluntary performance. Three databases were...
There is great variability in responsiveness to post-activation performance enhancement (PAPE). Factors such as greater expression of type II muscle fibers and experience with strength training are associated with greater responsiveness to PAPE. We i...
The gut microbiota can play an important role in enhancing the host’s complex immune system. In this regard, many studies indicate that probiotics consumption has a beneficial impact on alterations in the composition of the gut microbiota. Our...
Grid-forming converters (GFMCs) have gained significant attention for their functionality in grid voltage formation and grid-supportive services. However, managing harmonic distortions caused by nonlinear loads remains a critical challenge in weak gr...
Nowadays, the controllable synthesis of stable hierarchical metal–organic frameworks (MOFs) is very important for practical applications, especially in catalysis. Herein, a well-known chromium–benzenedicarboxylate metal–organic fram...
The accurate execution of aeroengine flight environment simulation tests relies on the electro-hydraulic servo valve control system in the altitude test facility. However, time delays arising from various factors, such as friction or sensor latency,...
Background: Despite noteworthy progress in the Expanded Program on Immunization (EPI) for improving vaccination coverage worldwide, inequalities in vaccine uptake and accessibility persist in several middle- and low-income states. Pakistan’s ro...
Sea ice, as an important component of the Earth’s ecosystem, has a profound impact on global climate and human activities due to its thickness. Therefore, the inversion of sea ice thickness has important research significance. Due to environmen...
This research provides a comprehensive evaluation of the phytochemical composition, antioxidant potential, and biological properties of four plant species with longstanding use in ethnobotanical traditions: Calendula officinalis, Mentha × piper...
This is a comprehensive review on the use of phospholipid nanovesicles for dermal/transdermal and nasal drug administration. Phospholipid-based vesicular carriers have been widely investigated for enhanced drug delivery via dermal/transdermal routes....
Numerous road accidents involving vulnerable road users result from their insufficient visibility to drivers. To increase the appeal of warning clothing and motivate consumers to use it, particularly in non-professional settings, an innovative high-v...
This study aimed to determine whether drop jump height will affect the post-activation performance enhancement (PAPE) effect at room temperature (RT) and low temperature (LT) conditions. Twelve male strength-trained males participated in this study....
The purpose of this study was to evaluate the immune-enhancing effect of red gamju fermented with Levilactobacillus brevis KU15154, isolated from kimchi, as a biofunctional beverage using mice. Thirty-two mice were used, and after a 2-week feeding, t...
To mitigate rotor vibrations in magnetic bearing systems arising from mass imbalance, this study proposes a novel suppression strategy that integrates the crested porcupine optimizer (CPO) with an enhanced linear active disturbance rejection control...
Agaricus blazei murrill (ABM), a large fungus, is reported to have extensive biological activities but the antioxidant and immune-regulatory capacities have been less studied and the components responsible for the functions are unclear. This study pr...
Phosphogypsum (PG) is the main by-product of wet-process phosphoric acid production. Its annual global production reaches about 200 million tons, yet its utilization rate remains low. Consequently, long-term stockpiling of large PG volumes poses imme...
A key event in the cytochrome c-dependent apoptotic pathway is the permeabilization of the outer mitochondrial membrane, resulting in the release of various apoptogenic factors, including cytochrome c, into the cytosol. It is believed that the permea...
The molecular basis of polymorphonuclear neutrophil (PMN) phagocytosis-enhancing activity (PEA) by human purified urinary Tamm-Horsfall glyco- protein (THP) has not been elucidated. In this study, we found human THP bound to lactoferrin (LF) and cath...
With the rapid development of the laying hen industry and the continuous innovation of farming technology, egg production continues to increase. Eggs are rich in proteins, lipids, and immunoglobulins (IgY) found in the egg yolk. IgY can be used to tr...
This study investigated the impact of post-activation performance enhancement (PAPE) on the parameters of the 3 min all-out test (3MT) in non-motorized tethered running, applying the concept of complex networks for integrative analysis. Ten recreatio...
30 November 2017
High solid anaerobic digestion (HSAD) is a rapidly developed anaerobic digestion technique for treating municipal sludge, and has been widely used in Europe and Asia. Recently, the enhanced HSAD process with thermal treatment showed its advantages in...
To have a sustainable city, human pressures on urban ecosystems should not exceed certain thresholds, which are defined by the urban carrying capacity concept. The main goal of this research was to monitor environmental pressures caused by the impact...
The development of poly(lactic acid) (PLA) nanocomposites incorporating urchin-like WO3 particles through a cost-effective solution-casting method has led to significant enhancements in structural, thermal, optical, and rheological properties. The in...
Exercise order is one of the significant factors modulating training effects. Therefore, the aim of this study was to compare the effectiveness of an 8-week complex (CPX) training program utilizing intra-CPX active recovery with compound training (CM...
The purpose of the present study was to investigate effect of post-activation performance enhancement (PAPE) induced by the eccentric half-squat exercise on vertical jump performance in male jumpers. The jumping height, peak power, and work were meas...
Jujube polysaccharides (ZJPA) and cyclic adenosine monophosphate (cAMP) are bioactive compounds with antioxidant and health-promoting potential, and their combination exhibits enhanced antioxidant activity. However, their limited stability and suscep...
This study explores the early-age performance of eco-efficient alkali-activated slag–fly ash (AASF) mixtures using high-calcium fly ash (HCFA) and low-calcium fly ash (LCFA) at varying alkali activator-to-slag cement (AL/SC) ratios (15%, 20%, a...
22 January 2022
Physical inactivity is considered a pandemic, requiring strong policy responses to address this major health issue. However, research on the development of Health-Enhancing Physical Activity policies (HEPA) remains scarce, particularly at the local l...
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