Aim: Sca-1+CD31− cells are resident cardiac progenitor cells, found in many mammalian tissues including the heart, and able to differentiate into cardiomyocytes in vitro and in vivo. Our previous work indicated that heart-derived Sca-1+CD31&min...
The identification of compounds and natural ingredients that can counteract tissue stress and dysfunction induced by aging in skin cells is warranted. Here, we investigated the activity of the secretion from the snail Cryptomphalus aspersa (SCA®)...
Inhibition of the prolyl-4-hydroxylase domain (PHD) enzymes, leading to the stabilization of hypoxia-inducible factor (HIF) α as well as to the stimulation of erythropoietin (Epo) synthesis, is the functional mechanism of the new anti-anemia dr...
Mechanized rice transplanting is a key method for large-scale cultivation. To enable rapid, accurate seedling detection and evaluate rice transplanting quality, this paper proposes an improved YOLOv12n model, YOLOv12n-SCA. First, this study embeds SC...
Crude oil is one of the strategic energies and plays an increasingly critical role effecting on the world economic development. The fluctuations of crude oil prices are caused by various extrinsic and intrinsic factors and usually demonstrate complex...
Background/Objectives: Cognitive impairment in spinocerebellar ataxia patients has been reported since the early-disease stage. We aimed to assess cognitive differences in SCA1 and SCA2 patients. Methods: We performed neuropsychological (NPS) and neu...
This research paper explores using marine shells as coarse aggregates in producing seawater sea sand UHPC-CA. The study examined factors such as coarse aggregates (granite, oyster shell, and cone shell), fine aggregates (sea sand and river sand), fib...
During coal resource mining, hard roof mining is prone to causing rock-burst disasters because traditional blasting–cutting roof technology has the disadvantages of low efficiency and high cost. This article studies the theoretical basis and en...
Due to the high price of fossil fuels, the increased carbon footprint in conventional generation units and the intermittent functionality of renewable units, alternative sources must contribute to the load frequency control (LFC) of the power system....
The influence of redundant implementations on success of physical attacks against cryptographic devices is currently under-researched. This is especially an issue in application fields such as wearable health, industrial control systems and the like...
Somatic mutations in EGFR and KRAS as well as chromosome rearrangements affecting ALK, ROS1, and RET have been identified in human lung adenocarcinoma (LUAD). We here developed organoid-based orthotopic and syngeneic mouse models for studies of the p...
Ocean surface wind vector (OWV) is a key variable for ocean remote sensing and tropical cyclone (TC) monitoring. This study presents the first comprehensive intercomparison of Ku-band OWV products from FY-3E/WindRAD and HY-2B/SCA scatterometers using...
Cryptographic algorithms (RSA, DSA, and ECC) use modular exponentiation as part of the principal operation. However, Non-profiled Side Channel Attacks such as Simple Power Analysis and Differential Power Analysis compromise cryptographic algorithms t...
Congenital heart disease (CHD) is a leading cause of death in children <1 year of age. Despite intense effort in the last 10 years, most CHDs (~70%) still have an unknown etiology. Conotruncal based defects, such as Tetralogy of Fallot (TOF), a co...
Over the past few decades, plenty of visualization software for the structural analysis of disordered/complex systems has been developed, but the uniqueness and correctness of structural quantification for such systems are still challenging. This pap...
Spinocerebellar ataxia type 3 (SCA3) is characterized by the over-repetitive CAG codon in the ataxin-3 gene (ATXN3), which encodes the mutant ATXN3 protein. The pathological defects of SCA3 such as the impaired aggresomes, autophagy, and the proteaso...
Bioshell calcium oxide (BiSCaO) possesses deodorizing properties and broad microbicidal activity. This study aimed to investigate the application of BiSCaO ointment for the prevention and treatment of infection in chronic wounds in healing-impaired p...
Spinocerebellar ataxia type 1 (SCA1) is a rare autosomal dominant inherited neurodegenerative disease caused by the expansion of glutamine (Q)-encoding CAG repeats in the gene ATAXIN1 (ATXN1). Patients with SCA1 suffer from movement and cognitive def...
Small Cajal body-associated RNAs (scaRNAs) are essential for biochemical modification of spliceosomal RNAs and spliceosome function. Changes in scaRNA expression level have been associated with developmental issues, including cancer and congenital he...
Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative dis-ease caused by the expansion of cytosine–adenine–guanine (CAG) repeats in the ataxin-1 (ATXN1) gene, leading to toxic gain-of-function of the ataxin-1 (AT...
Variants in STUB1 cause both autosomal recessive (SCAR16) and dominant (SCA48) spinocerebellar ataxia. Reports from 18 STUB1 variants causing SCA48 show that the clinical picture includes later-onset ataxia with a cerebellar cognitive affective syndr...
Spinocerebellar ataxia type 5 (SCA5) is a neurodegenerative disease caused by mutations in the SPTBN2 gene encoding the cytoskeletal protein β-III-spectrin. Previously, we demonstrated that a L253P missense mutation, localizing to the β-III...
Spinocerebellar ataxias (SCAs) constitute a heterogeneous group of more than 40 autosomal-dominant genetic and neurodegenerative diseases characterized by loss of balance and motor coordination due to dysfunction of the cerebellum and its efferent co...
Background: Childhood-onset progressive ataxias are rare neurodegenerative disorders characterized by cerebellar signs, sometimes associated with other neurological or extra-neurological features. The autosomal dominant forms, known as spinocerebella...
Shrinkage during hardening and curing is one of the largest challenges for the widespread application of metakaolin-based geopolymers (MKGs). To solve this problem, a silane coupling agent (SCA) and waterborne epoxy resin (WER) were used to synthesiz...
KCND3 encodes the voltage-gated potassium channel KV4.3 that is highly expressed in the cerebellum, where it regulates dendritic excitability and calcium influx. Loss-of-function KV4.3 mutations have been associated with dominant spinocerebellar atax...
In deep learning-based side-channel analysis (DL-SCA), there may be a proliferation of model parameters as the number of trace power points increases, especially in the case of raw power traces. Determining how to design a lightweight deep learning m...
Dysfunctional mitochondria are present in many neurodegenerative diseases, such as spinocerebellar ataxia type 3 (SCA3), also known as Machado–Joseph disease (MJD). SCA3/MJD, the most frequent neurodegenerative ataxia worldwide, is caused by th...
Urban unmanned aerial vehicle (UAV) scenes exhibit strong directional structure, and their foreground composition varies substantially across frames. Coordinate Attention encodes directional information through axis-wise pooling, but its gates are pr...
Strong customer authentication (SCA) is a requirement of the European Union Revised Directive on Payment Services (PSD2) which ensures that electronic payments are performed with multifactor authentication. While increasing the security of electronic...
Background/Objectives: The Ataxin-2 protein (ATXN2) plays an essential role in RNA metabolism and many cellular processes. Dysregulation or mutation of the Ataxin-2 gene (ATXN2) can lead to neurodegenerative diseases such as spinocerebellar ataxia ty...
Candida auris is an emerging multidrug-resistant yeast causing nosocomial infections and associated with high mortality in immunocompromised patients. Rapid identification and characterisation are necessary for diagnosis and containing its spread. In...
Carbon fiber mesh reinforced cement-based composites (CMCCs) have received extensive attention in the field of engineering repair and structural reinforcement due to their outstanding properties such as two-way force, rust prevention, high specific s...
Blind source separation (BSS) recovers source signals from observations without knowing the mixing process or source signals. Underdetermined blind source separation (UBSS) occurs when there are fewer mixes than source signals. Sparse component analy...
Deep neural networks have been deployed in various hardware accelerators, such as graph process units (GPUs), field-program gate arrays (FPGAs), and application specific integrated circuit (ASIC) chips. Normally, a huge amount of computation is requi...
This paper deals with the problem of the optimal placement and sizing of distributed generators (DGs) in alternating current (AC) distribution networks by proposing a hybrid master–slave optimization procedure. In the master stage, the discrete...
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The spinocerebellar ataxias (SCA) are a group of autosomal dominantly inherited ataxias that are clinically characterised by progressive ataxia. Until now, 13 genetically distinct SCA subtypes have been identified. In 5 of these disorders (SCA1, SCA2...
The RGB and thermal (RGB-T) object tracking task is challenging, especially with various target changes caused by deformation, abrupt motion, background clutter and occlusion. It is critical to employ the complementary nature between visual RGB and t...
This paper discusses the use of a stochastic metaheuristic population-based optimization algorithm known as the sine cosine algorithm (SCA) to design the parameters of a power system stabilizer (PSS) for damping electromechanical oscillations in a si...
CONFISCA is the first generic SIMD-based software countermeasure that can concurrently resist against Side-Channel Attack (SCA) and Fault Injection (FI). Its promising strength is presented in a PRESENT cipher case study and compared to software-base...
Increasing experience in the use of PLLA-SCA™ suggests that a brief overview of recent studies and a standardization of treatment protocols based on new clinical data should be beneficial. The aim of this article is to provide guidance on the u...
Antifungal proteins (AFPs) from ascomycete fungi could help the development of antimycotics. However, little is known about their biological role or functional interactions with other fungal biomolecules. We previously reported that AfpB from the pos...
Bud eye identification is a critical step in the intelligent seed cutting process for potatoes. This study focuses on the challenges of low testing accuracy and excessive weighted memory in testing models for potato bud eye detection. It proposes an...
Remote sensing observations of snow-covered areas (SCA) are important for monitoring and modeling energy balances, hydrologic processes, and climate change. For an agricultural field, we produced 12 snow cover maps from UAS imagery during an approxim...
Hypoxia is one of the most frequent and severe stresses to an organism’s homeostatic mechanisms, and hypoxia during gestation has profound adverse effects on the heart development increasing the occurrence of congenital heart defects (CHDs). Ca...
Type 1 spinocerebellar ataxia (SCA1) is a progressive neurodegenerative disorder with no effective treatment to date. Using mice modeling SCA1, it has been demonstrated that a drug that amplifies mGlu1 receptor activation (mGlu1 receptor PAM, Ro07114...
Accurately extracting buildings is essential for urbanization rate statistics, urban planning, resource allocation, etc. The high-resolution remote sensing images contain rich building information, which provides an important data source for building...
Very-high-resolution (VHR) optical imaging satellites can offer precise, accurate, and direct measurements of snow-covered areas (SCA) with sub-meter to meter-scale resolution in regions of complex land cover and terrain. We explore the potential of...
Glaciers and snow are critical components of the hydrological cycle in the Himalayan region, and they play a vital role in river runoff. Therefore, it is crucial to monitor the glaciers and snow cover on a spatiotemporal basis to better understand th...
Feature selection is the procedure of extracting the optimal subset of features from an elementary feature set, to reduce the dimensionality of the data. It is an important part of improving the classification accuracy of classification algorithms fo...
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