- Article
Revealing the Mechanism of NLRP3 Inflammatory Pathway Activation through K+ Efflux Induced by PLO via Signal Point Mutations
- Qiang Shan,
- Wenbo Ma,
- Bolin Li,
- Qian Li,
- Xue Wang,
- Yanan Li,
- Jiufeng Wang,
- Yaohong Zhu and
- Ning Liu
Trueperella pyogenes is an important opportunistic pathogenic bacterium widely distributed in the environment. Pyolysin (PLO) is a primary virulence factor of T. pyogenes and capable of lysing many different cells. PLO is a member of the cholesterol-...