Olive flounder (Paralichthys olivaceus) is a commercially important fish species in Japan, China, and the Republic of Korea. Despite numerous attempts to improve productivity, there have been no studies of in vitro germline stem cell (GSC) culture in...
Background: Depression-like phenotypes in animal models often show graded behavioral variation rather than uniform group-wise changes, yet treatment effects are still commonly evaluated using categorical comparisons. In particular, it remains difficu...
Optical fibre micro/nano tips (OFTs), defined here as tapered fibres with a waist diameter ranging from a few microns to tens of nanometres and different tip angles (i.e., from tens of degrees to fractions of degrees), represent extremely versatile t...
The optical feedback tolerance (OFT) of a distributed Bragg reflector (DBR) laser was investigated experimentally. The static and modulation performance of the DBR laser under optical feedback was examined by evaluating its relative intensity noise (...
In vitro 3D cell culture systems provide a physiologically relevant microenvironment that mimics native tissue architecture. However, establishing functional 3D testicular aggregates in teleosts remains challenging. In this study, we established a no...
The antidepressant-like activity of ethanol extract of Ziziphus jujuba Mill var. spinosa seeds (Semen Ziziphi Spinosae, SZS) was investigated by behavioral tests, such as a forced swimming test (FST), a tail-suspension test (TST), and an open field t...
Extremely low-resource machine translation poses a difficult cross-lingual adaptation problem: improving target-language performance while preserving capabilities acquired through multilingual pretraining. This study compares three mathematically dis...
The neural crest (NC) is a multipotent and temporarily migratory cell population stemming from the dorsal neural tube during vertebrate embryogenesis. Cardiac neural crest cells (NCCs), a specified subpopulation of the NC, are vital for normal cardio...
The diffusion and application of advanced and applicable agricultural technologies serve as critical support for realizing the green transition and promoting high-quality agricultural development. This study constructs a two-dimensional analytical fr...
Mental disorders are psychological symptoms that impact multiple areas of an individual’s life. Depression and anxiety are chronic illnesses described as the most prevalent stress-related mood disorders that cause injury and early death. In Morocco,...
Metaphor understanding can be tricky for children until mid-childhood, yet some research suggests that pre-schoolers are already competent. Many factors have been proposed to play a role in the development of metaphor comprehension. In this study we...
Background: Bispecific antibodies have emerged as a promising class of therapeutics, enabling simultaneous targeting of two distinct antigens. Single-domain antibodies (sdAbs) comprising camelid variable heavy chains (VHHs) provide a compact and adap...
We report the case of a 78-year-old female patient who received palliative immunotherapy with pembrolizumab and lenvatinib as a treatment of pulmonary and osseous metastatic endometrial carcinoma. Under this therapy, the patient developed dysphagia,...
Mild traumatic brain injuries (mTBIs) are highly prevalent and can lead to chronic behavioral and cognitive deficits often associated with the development of neurodegenerative diseases. Oxidative stress and formation of reactive oxygen species (ROS)...
Background: Anxiety refers to the pathological persistence and intensification of emotional responses to danger, affecting health from psychological and physical aspects. Serotonin is an important neurotransmitter involved in the onset of anxiety. Me...
The special affine Fourier transform (SAFT) is an extended version of the classical Fourier transform and incorporates various signal processing tools which include the Fourier transforms, the fractional Fourier transform, the linear canonical transf...
We analyzed the publication output of one of the 1987 Nobel Prize awardees, K. Alex Müller, using bibliometric methods. The time-dependent number of publications and citations and the network with respect to the coauthors and their affiliations...
The optical Freedericksz transition (OFT) can reversibly control the molecular orientation of liquid crystals (LCs) only by light irradiation, leading to the development of all-optical devices, such as smart windows. In particular, oligothiophene-dop...
Anomalies in the cardiac outflow tract (OFT) are among the most frequent congenital heart defects (CHDs). During embryogenesis, the cardiac OFT is a dynamic structure at the arterial pole of the heart. Heart tube elongation occurs by addition of cell...
Oil spills on the sea surface have caused serious harm to the marine ecological environment and coastal environment. Oil film thickness (OFT) is an important parameter for estimating oil spills amount, and accurate quantification of OFT is of great s...
Persistent truncus arteriosus (PTA) is an uncommon and complex congenital cardiac malformation accounting for about 1.2% of all congenital heart diseases (CHDs), which is caused by a deficiency in the embryonic heart outflow tract’s (OFT) septa...
Whilst knowledge regarding the pathophysiology of congenital heart disease (CHDs) has advanced greatly in recent years, the underlying developmental processes affecting the cardiac outflow tract (OFT) such as bicuspid aortic valve, tetralogy of Fallo...
Cardiac valve structure and function are primarily determined during early development. Consequently, abnormally-formed heart valves are the most common type of congenital heart defects. Several adult valve diseases can be backtracked to abnormal val...
Congenital heart defects (CHDs) represent the most common form of human birth defects; approximately one-third of heart defects involve malformations of the outflow tract (OFT). Maternal diabetes increases the risk of CHD by 3–5 fold. During heart or...
We analyzed heart wall motion and blood flow dynamics in chicken embryos using in vivo optical coherence tomography (OCT) imaging and computational fluid dynamics (CFD) embryo-specific modeling. We focused on the heart outflow tract (OFT) region of d...
Background/Objectives: We aimed to evaluate the evidence regarding the effect of greater omentum flap transposition (OFT) on low anterior resection syndrome (LARS) in patients who undergo rectal resections. Methods: This study was conducted according...
Group management is practiced to deploy access control and to ease multicast and broadcast communication. However, the devices that constitute the Internet of Things (IoT) are resource-constrained, and the network of IoT is heterogeneous with variabl...
Co-inoculation of soybeans with Bradyrhizobium and plant growth-promoting bacteria has displayed promise for enhancing plant growth, but concrete evidence of its impact on soybean yields is limited. Therefore, this study assessed the comparative effi...
Gene inactivation in model organisms has identified numerous genes and signaling pathways involved in mammalian cardiac outflow tract (OFT) development. Human genetics data have implicated the VEGFR3 gene in OFT development, but when and where it is...
Blood flow is critical for normal cardiac development. Hemodynamic stimuli outside of normal ranges can lead to overt cardiac defects, but how early heart tissue remodels in response to altered hemodynamics is poorly understood. This study investigat...
Approximately 2.5% of adults have aortic valve disease (AVD), which is often accompanied by ascending aortic artery (AscAo) malformations (aortopathies). Despite the prevalence, there are no pharmacologic treatments for AVD. To identify novel factors...
The essential oils of the Osmanthus fragrans tea (OFT), Osmanthus fragrans (OF) and green tea (GT) had been extracted by steam distillation and analyzed by gas chromatography-mass spectrometry (GC-MS) with the help of heuristic evolving latent projec...
Congenital heart defects (CHDs) occur with such a frequency that they constitute a significant cause of morbidity and mortality in both children and adults. A significant portion of CHDs can be attributed to aberrant development of the cardiac outflo...
Inductive powering for implanted medical devices, such as implantable biosensors, is a safe and effective technique that allows power to be delivered to implants wirelessly, avoiding the use of transcutaneous wires or implanted batteries. Wireless po...
In the pathogenesis of depression, heredity is believed to be a major factor. However, the mechanism by which heredity contributes to the onset of depression is not fully understood. Wistar Kyoto (WKY) rats have been used as an animal model for depre...
1 January 2005
Die öffentliche Thematisierung der Psychiatrie ist oft gleichbedeutend mit ihrer Kritik
The hydrogen peroxide-immobilized commercial catalase system was chosen to estimate the optimal feed temperature (OFT) for fixed-bed reactor (FXBR). This feed temperature was obtained based on analytical solution by maximizing the time-averaged subst...
Erythrocyte osmotic fragility is an excellent parameter for evaluating the red blood cell (RBC) membrane, which may be abnormal in several pathological conditions. The flow cytometer is a powerful tool that analyzes a single cell in a solution and ca...
The effectiveness of protective coatings based on 3-(2,2,3,3,4,4,5,5-octafluoropentyloxy)propyltriethoxysilane (OFTES) in protecting concrete surfaces against water was tested. For the synthesis of OFTES, 2,2,3,3,4,4,5,5-octafluoropentanol, which is...
1 January 2003
Die Autorin greift ein oft vernachlässigtes Thema, den Einfluss der Multiplen Sklerose auf die Familie, auf [...]
The synthesis of melatonin (MLT) physiologically decreases during aging. Treatment with MLT has shown anxiolytic, hypnotic, and analgesic effects, but little is known about possible age-dependent differences in its efficacy. Therefore, we studied the...
This study examined the effects of exposure to coloured LED lights on some behavioural responses, food and water consumption, and live weight in budgerigars kept in captivity using behavioural tests to compare different lighting conditions. Budgeriga...
1 January 2004
In der psychodiagnostischen und -therapeutischen Arbeit mit Kindern reicht der sprachliche Dialog allein oft nicht aus, um eine gemeinsame bedeutungsvolle Beziehungsebene zu erreichen [...]
The therapy of depression is challenging and still unsatisfactory despite the presence of many antidepressant drugs on the market. Consequently, there is a continuous need to search for new, safer, and more effective antidepressant therapeutics. Prev...
Background/Objectives: Alzheimer’s disease is a neurodegenerative disorder characterized by the accumulation of both amyloid and tau pathology. Lifestyle factors, including exercise, have been shown to be protective against dementia and warrant...
Depression is considered a neuropsychic disease that has global prevalence and is associated with disability. The pathophysiology of depression is not well understood; however, emerging evidence has indicated that neuroinflammation could contribute t...
Early cow–calf separation management induced various welfare problems for dairy calves. We mimicked the maternal licking by manually brushing right after the Holstein female calves were born and during their first week of life, termed artificia...
Cornelia de Lange Syndrome (CdLS) patients, who frequently carry a mutation in NIPBL, present an increased incidence of outflow tract (OFT)-related congenital heart defects (CHDs). Nipbl+/- mice recapitulate a number of phenotypic traits of CdLS pati...
1 January 2006
Der Schlaganfall ist die häufigste Ursache für eine Langzeitbehinderung bei älteren Erwachsenen mit oft gravierenden sozioökonomischen Folgen. Eine möglichst optimale Erholung von einem Schlaganfall ist deshalb nicht nur aus Patientensicht, sondern a...
Post-intensive care syndrome (PICS) is a physical, cognitive, and mental impairment observed in intensive care unit (ICU) survivors. Although this is an emerging problem in the ICU, how sepsis induces the characteristic symptoms of PICS remains uncle...
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