Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot
A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425).
Deadline for manuscript submissions: closed (1 August 2021) | Viewed by 91837
Special Issue Editors
2. Department of Cardiology, Leiden University Medical Center, 2300RC Leiden, The Netherlands
Interests: congenital heart disease; cardiac development; conduction system development; animal models of congenital heart disease and arrhythmias; clinical aspects of arrhythmia; electrophysiology; cardiovascular morphology
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2. Institute of Biology IBL, University of Leiden, Sylviusweg 72, 2333BE Leiden, The Netherlands
Interests: cardiac development and septation; animal models; evolutionary biology; congenital anomalies; epicardium; biomechanics; imaging
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Special Issue Information
The arterial pole is one of the most complex parts of the heart both in development and disease. It involves the collaboration and orchestration of contributions from the first and second heart fields as well as the neural crest. The precursor cells differentiate into endocardial cushions and putative cardiac valves, the myocardium, and epicardium of the heart, but also into the different layers of the main arterial vessels. These include not only the aorta and the pulmonary trunk but also the pulmonary and coronary arteries, and during development, the arterial duct. Many transcriptional and signaling networks act in timely concert to acquire the proper asymmetric development and function and pressure and flow dynamics. This is not only a human or even mammalian ‘enterprise,’ but is also taking place in so-called ancestral forms from fish to reptiles, including birds. In humans, it is small wonder that many clinical syndromes may arise when something in this complexity is amiss.
In this special issue of JCDD, we welcome contributions focussed on the heart fields, congenital cardiac malformations and associated syndromes, with special emphasis on the cardiac outflow tract.
The issue is devoted to Prof. Dr. Adriana Gittenberger-de Groot, who dedicated her extensive career to research on cardiovascular development.
Dr. Monique R.M. Jongbloed
Prof. Dr. Robert Poelmann
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Cardiac development
- Congenital heart disease
- Gene expression
- Transcription
- Signaling networks
- Hemodynamics
- Evolution
- Aortic sac
- Outflow tract septation
- First/Second heart field
- Neural crest
- Pharyngeal arch arteries
- Semilunar valves
- Coronary arteries
- Cardiopulmonary circulation
- Ductus arteriosus
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