Special Issue "Studies on Developmental Genetic Programs of Animal Early Embryogenesis"
Deadline for manuscript submissions: 15 November 2023 | Viewed by 9655
The fertilization of oocyte and sperm, to produce a new organism, is the culmination of numerous intricately regulated cellular processes. After fertilization, gametes develop from a highly differentiated state to a pluripotent state, and then undergo early embryogenesis, which is considered to be one of the most crucial phases of the entire lifespan. During this process, paternal and maternal chromatin structures and genomes undergo dramatic changes, with the latter experiencing genome-wide epigenetic modifications or reprogramming. The transcriptome, proteome, and metabolome of the early embryo also exhibit significant transformations, all of which could regulate the events of embryonic development and even the entire lifespan or offspring.
Until now, several important theories and mechanisms concerning the regulation of animal early embryogenesis have been elucidated, triggering the emergence of important technologies such as assisted reproduction, animal breeding, the creation of gene-editing animals, and so on. However, the early embryonic development process is complex, and its mechanisms are not fully understood.
This Special Issue will focus on valuable findings associated with the genetic programs of animal early embryogenesis, exploiting a new understanding for animal embryos.
Prof. Dr. Enqi Liu
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- zygotic genome activation
- chromatin structure