The Cardiac Neural Crest Cells in Heart Development and Congenital Heart Defects
Abstract
:1. Introduction
2. Contributions of the Cardiac Neural Crest to Cardiac Formation
3. NC Associated Cardiac Congenital Abnormalities in Humans
3.1. DiGeorge Syndrome
3.2. CHARGE Syndrome
3.3. Treacher Collins Syndrome
4. Multiple Regulatory Pathways in NC-Derived CHDs
4.1. Notch Signaling Pathway
4.2. Bmp Signaling
4.3. Hippo-Yap Signaling Pathway
4.4. BAF Signaling Complex
4.5. Transcription Factors Indicated in NC-Derived Heart Development and Associated CHDs
5. Conclusions and Future Perspective
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
Abbreviations
References
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Erhardt, S.; Zheng, M.; Zhao, X.; Le, T.P.; Findley, T.O.; Wang, J. The Cardiac Neural Crest Cells in Heart Development and Congenital Heart Defects. J. Cardiovasc. Dev. Dis. 2021, 8, 89. https://doi.org/10.3390/jcdd8080089
Erhardt S, Zheng M, Zhao X, Le TP, Findley TO, Wang J. The Cardiac Neural Crest Cells in Heart Development and Congenital Heart Defects. Journal of Cardiovascular Development and Disease. 2021; 8(8):89. https://doi.org/10.3390/jcdd8080089
Chicago/Turabian StyleErhardt, Shannon, Mingjie Zheng, Xiaolei Zhao, Tram P. Le, Tina O. Findley, and Jun Wang. 2021. "The Cardiac Neural Crest Cells in Heart Development and Congenital Heart Defects" Journal of Cardiovascular Development and Disease 8, no. 8: 89. https://doi.org/10.3390/jcdd8080089
APA StyleErhardt, S., Zheng, M., Zhao, X., Le, T. P., Findley, T. O., & Wang, J. (2021). The Cardiac Neural Crest Cells in Heart Development and Congenital Heart Defects. Journal of Cardiovascular Development and Disease, 8(8), 89. https://doi.org/10.3390/jcdd8080089