The immune response triggered when plant cell surface receptors recognize pathogen-associated molecular patterns (PAMPs) is known as PAMP-triggered immunity (PTI). Several studies have demonstrated that extracellular plant ferredoxin-like protein (PF...
The frontline of plant defense against non-viral pathogens such as bacteria, fungi and oomycetes is provided by transmembrane pattern recognition receptors that detect conserved pathogen-associated molecular patterns (PAMPs), leading to pattern-trigg...
This paper investigates the performance-constrained formation control issues for multiple underactuated unmanned surface vehicles (USVs) under uncertain dynamics and the limited communication bandwidth. Firstly, an auxiliary input–output transf...
In both monoclonal gammopathy of uncertain significance (MGUS) and multiple myeloma (MM) patients, immune functions are variably impaired, and there is a high risk of bacterial infections. Neutrophils are the most abundant circulating leukocytes and...
At the core of proper mitochondrial functionality is the maintenance of its structure and morphology. Physical changes in mitochondrial structure alter metabolic pathways inside mitochondria, affect mitochondrial turnover, disturb mitochondrial dynam...
Carotenoids are well known for their potent antioxidant function in the cellular system. However, in cancer cells with an innately high level of intracellular reactive oxygen species (ROS), carotenoids may act as potent pro-oxidant molecules and trig...
Four-dimensional (4D) printing is an innovative additive manufacturing technology used to fabricate structures that can evolve over time when exposed to a predefined environmental stimulus. 4D printed objects are no longer static objects but programm...
Ferroptosis, a form of iron-dependent, lipid peroxidation-driven cell death, has been extensively investigated in recent years, and several studies have suggested that the ferroptosis-inducing properties of iron-containing nanomaterials could be harn...
This article provides a thorough overview of the biomarkers, pathophysiology, and molecular pathways involved in the transition from acute kidney injury (AKI) and acute kidney disease (AKD) to chronic kidney disease (CKD). It categorizes the biomarke...
In this paper, an event-triggered optimal control strategy is proposed for three-phase grid-connected voltage source inverters (VSIs) based on the voltage-modulated direct power control (VM-DPC) principle. The optimization control problem of VSIs is...
17 December 2021
A sedentary lifestyle is associated with overweight/obesity, which involves excessive fat body accumulation, triggering structural and functional changes in tissues, organs, and body systems. Research shows that this fat accumulation is responsible f...
Polymorphonuclear neutrophils (PMN) are the most abundant leucocytes in the circulation in humans. They represent a heterogeneous population exerting diverse functions through several activities. Usually described as typical pro-inflammatory cells, i...
Mixed-signal integrated circuits (ICs) play an eminent and critical role in design and development of the embedded systems leveraged within smart weapons and military systems. These ICs can be a golden target for adversaries to compromise in order to...
FPGA-RICH is an FPGA-based online partial particle identification system for the NA62 experiment employing AI techniques. Integrated between the readout of the Ring Imaging Cherenkov detector (RICH) and the low-level trigger processor (L0TP+), FPGA-R...
An efficient and straightforward approach for the synthesis of carbamoylated chroman-4-ones has been well-developed. The reaction is triggered through the generation of carbamoyl radicals from oxamic acids under metal-free conditions, which subsequen...
In the design of multi-loop Networked Control Systems (NCSs), wherein each control system is characterized by heterogeneous dynamics and associated with a certain set of timing specifications, appropriate metrics need to be employed for the synthesis...
Trigger finger (TF) is a common debilitating hand disorder that often results in pain and functional limitations. Currently accepted conservative treatments include splinting, nonsteroidal anti-inflammatory drugs, and corticosteroid injections. Recen...
Pyrvinium pamoate, a widely-used anthelmintic agent, reportedly exhibits significant anti-tumor effects in several cancers. However, the efficacy and mechanisms of pyrvinium against myeloid leukemia remain unclear. The growth inhibitory effects of py...
Functional electrical stimulation and robot-assisted gait training are techniques which are used in a clinical routine to enhance the rehabilitation process of stroke patients. By combining these technologies, therapy effects could be further improve...
With the successful completion of genomic sequencing for Brassica napus, identification of novel genes, determination of functions performed by genes, and exploring the molecular mechanisms underlying important agronomic traits were challenged. Mutag...
We previously introduced the brain erythropoietin (EPO) circle as a model to explain the adaptive ‘brain hardware upgrade’ and enhanced performance. In this fundamental circle, brain cells, challenged by motor-cognitive tasks, experience functional h...
The glucagon-like peptide-1 receptor (GLP-1R) plays a key role in metabolism and is an important therapeutic target in diabetes and obesity. Recent studies in experimental animals have shown that certain subsets of T cells express functional GLP-1R,...
This paper features the synthesis of thrombin-responsive, nucleic acid-gated, UiO-68 metal–organic framework nanoparticles (NMOFs) loaded with the drug Apixaban or rhodamine 6G as a drug model. Apixaban acts as an inhibitor of blood clots forma...
Salivarian trypanosomes are extracellular parasites causing anthroponotic and zoonotic infections. Anti-parasite vaccination is considered the only sustainable method for global trypanosomosis control. Unfortunately, no single field applicable vaccin...
Migraine, the most frequent neurological ailment, affects visual processing during and between attacks. Most visual disturbances associated with migraine can be explained by increased neural hyperexcitability, as suggested by clinical, physiological...
Inflammasomes are important intracellular multiprotein signaling complexes that modulate the activation of caspase-1 and induce levels of the proinflammatory cytokines interleukin-1β (IL-1β) and IL-18 in response to pathogenic microorganisms and mole...
Evasion of immune surveillance is an accepted hallmark of tumor progression. The production of immune suppressive mediators by tumor cells is one of the major mechanisms of tumor immune escape. Galectin-1 (Gal-1), a pivotal immunosuppressive molecule...
The effect of stress depolarization will cause actuation function degradation of a piezoelectric actuator, which can eventually trigger function failure of the piezoelectric smart structure system. In the present study, we experimentally demonstrate...
The tumor suppressor protein p53 is often called “the genome guardian” and controls the cell cycle and the integrity of DNA, as well as other important cellular functions. Its main function is to trigger the process of apoptosis in tumor...
This paper is concerned with the consensus of a system involving multiple underactuated autonomous underwater vehicles (AUVs). Combined with a dynamic event-triggered mechanism and a fixed-time stability theorem, the backstepping average consensus co...
The interface between the cellular actin network and diverse forms of integrin-mediated cell adhesions displays a unique capacity to serve as accurate chemical and mechanical sensors of the cell’s microenvironment. Focal adhesion-like structure...
Subtilase cytotoxin (SubAB) is the prototype of a new AB5 toxin family produced by a subset of Shiga toxigenic Escherichia coli (STEC) strains. Its A subunit is a subtilase-like serine protease and cytotoxicity for eukaryotic cells is due to a highly...
Inflammation is the key for the initiation and progression of atherosclerosis. Accumulating evidence has revealed that an altered gut microbiome (dysbiosis) triggers both local and systemic inflammation to cause chronic inflammatory diseases, includi...
The emerged field of non-thermal plasma (NTP) shows great potential in the alteration of cell redox status, which can be utilized as a promising therapeutic implication. In recent years, the NTP field considerably progresses in the modulation of immu...
The context ultimately decides on mobility options and thus shapes mobility behavior. Nudges are an increasingly used strategy for promoting sustainable modes of everyday mobility. However, in most cases, the design of nudges and the triggers for iss...
The cholinergic system plays an essential role in brain development, physiology, and pathophysiology. Herein, we review how specific alterations in this system, through genetic mutations or abnormal receptor function, can lead to aberrant neural circ...
Celiac disease (CD) is a chronic inflammation of the small intestine triggered by gluten ingestion in genetically predisposed people. Recent literature studies highlight the possible role of the gut microbiota in the pathogenesis of this disease. The...
Networked nonlinear systems (NNSs) have great potential security threats because of malicious attacks. These attacks will destabilize the networked systems and disrupt the communication to the networked systems, which will affect the stability and pe...
With the proportion of air conditioners increasing gradually, they can provide a certain amount of frequency-controlled reserves for a micro-grid. Optimizing utilization of air conditioners and considering load response characteristics and customer c...
This article is concerned with the adaptive-event-triggered filtering problem as it relates to a class of nonlinear discrete-time systems characterized by interval Type-2 fuzzy models. The system under investigation is susceptible to Markovian switch...
This paper presents a resilient observer-based and event-triggered control scheme for discrete-time Cyber–Physical Systems (CPS) under Markovian Cyber-Attacks (MCA). The proposed framework integrates a Luenberger observer for cyberattack detect...
We study the behavior of poly(methyl methacrylate) (PMMA) exposed to femtosecond pulses of extreme ultraviolet and X-ray laser radiation in the single-shot damage regime. The employed microscopic simulation traces induced electron cascades, the therm...
Retinopathy of prematurity (ROP) is one of the main blinding diseases affecting preterm newborns and is classically considered a vascular disorder. The premature exposure to the extrauterine environment, which is hyperoxic in respect to the intrauter...
Activated microglia act as a double-edged sword for stroke. In the acute phase of stroke, activated microglia might deteriorate neurological function. Therefore, it is of great clinical transforming potential to explore drugs or methods that can inhi...
This study aimed to determine the effects of balance training with weight shift-triggered electrical stimulation to improve balance, lower-extremity motor function, and activities of daily living in patients with stroke. The participants were randoml...
For multi-agent systems under Denial-of-Service (DoS) attacks, a relative threshold strategy for event triggering and a state-constrained control method with prescribed performance are proposed. Within the framework of combining graph theory with the...
The development of mechanochromic fluorophors with high-brightness, solid-state fluorescence is very significant and challenging. Herein, highly solid-state emissive triphenylamine, carbazole and tetraphenylethylene-functionalized benzothiadiazole de...
Patients diagnosed with the primary headache disorder known as cluster headache (CH) commonly report that their headache attacks occur in patterns of both circadian and seasonal rhythmicity. Vitamin D is essential for a variety of bodily functions an...
In dry age-related macular degeneration (AMD), inflammation plays a key role in disease pathogenesis. Innate immune cells such as microglia and neutrophils infiltrate the sub-retinal space (SRS) to induce chronic inflammation and AMD progression. But...
Freezing of Gait (FoG) is one of the most debilitating symptoms of Parkinson’s disease and is an important contributor to falls. When the management of freezing episodes cannot be achieved through medication or surgery, non-pharmacological meth...
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