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Special Issue "Actin and Its Associates: Biophysical Aspects in Functional Roles"
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biophysics".
Deadline for manuscript submissions: 30 April 2023 | Viewed by 3231
Special Issue Editors
Interests: actin related protein 2-3 complex; actin depolymerizing factors; microfilaments
Interests: actin and associated proteins cooperating in cell anchorage, cell motility, cell-cell-interactions, tissue generation, in health and disease
Interests: actin cytoskeleton; actin-binding proteins; actin structure and dynamics; functional polymorphism of actin; actin-microtubule crosstalk
Special Issue Information
Actin, a ubiquitous cellular protein, is vital to a multitude of cell functions relying on force generation and transduction such as cellular motility, transport and division, cell shaping and polarity. Within the cohesive structure of the actin cytoskeleton, helical polymers assembled from actin monomers self-organize into higher-order networks with diverse structural, dynamic, and mechanical properties fine-tuned by an inventory of actin-binding proteins. These distinct assemblies serve specialized roles in cell response and behavior. Significant advances have been made to unravel how the functional polymorphism of the actin cytoskeleton emerges from actin’s intrinsic physicochemical features. However, challenges remain in the understanding of the mechanisms coupling the molecular pattern of actin networks with their biomechanical and functional behavior. In this Special Issue of Biomolecules, original research publications are invited that cover the recent advances related to the biophysical principles governing the architecture, dynamics, and function of actin polymers and networks either isolated in solution or in the cellular environment. The Special Issue is also a place for review articles summarizing the existing knowledge on the mechanical aspects and regulation of actin homeostasis in health and disease.
Prof. Dr. Hans Georg Mannherz
Prof. Dr. Brigitte M. Jockusch
Dr. Beáta Bugyi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- actin isoforms and mutations
- actin cytoskeleton
- actin-binding proteins
- actin dynamics
- polymer mechanics
- biophysical and cell biological approaches and biomedical con sequences