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129 Results Found

  • Article
  • Open Access
34 Citations
13,857 Views
13 Pages

Beverage Intake Assessment Questionnaire: Relative Validity and Repeatability in a Spanish Population with Metabolic Syndrome from the PREDIMED-PLUS Study

  • Cíntia Ferreira-Pêgo,
  • Mariela Nissensohn,
  • Stavros A. Kavouras,
  • Nancy Babio and ,
  • Lluís Serra-Majem,
  • Adys Martín Águila,
  • Andy Mauromoustakos,
  • Jacqueline Álvarez Pérez and
  • Jordi Salas-Salvadó
  • + 4 authors+ 0 author

30 July 2016

We assess the repeatability and relative validity of a Spanish beverage intake questionnaire for assessing water intake from beverages. The present analysis was performed within the framework of the PREDIMED-PLUS trial. The study participants were ad...

(This article belongs to the Special Issue Beverage Consumption Habits around the World: Association with Total Water and Energy Intakes)
  • Article
  • Open Access
3 Citations
3,306 Views
13 Pages

Life’s Simple 7 and Risk of Peripheral Artery Disease: Results from the PREDIMED Study and an Updated Meta-Analysis

  • Nieves López-Laguna,
  • Estefanía Toledo,
  • María S. Hershey,
  • Nancy Babio and ,
  • José V. Sorlí,
  • Emilio Ros,
  • Miguel Ángel Muñoz,
  • Ramón Estruch,
  • José Lapetra and
  • Miguel Ruiz-Canela
  • + 14 authors+ 9 authors

20 June 2025

Background: Peripheral artery disease (PAD) is a major vascular condition often overlooked in prevention strategies. We aimed to evaluate the association between cardiovascular health, measured by Life’s Simple 7 (LS7), and the risk of PAD in a...

(This article belongs to the Special Issue Nutrition and Exercise Interventions on Vascular Function and Adaptation)
  • Article
  • Open Access
9 Citations
7,933 Views
19 Pages

Dietary Intake in Population with Metabolic Syndrome: Is the Prevalence of Inadequate Intake Influenced by Geographical Area? Cross-Sectional Analysis from PREDIMED-Plus Study

  • Naomi Cano-Ibáñez,
  • Aurora Bueno-Cavanillas,
  • Miguel A. Martínez-González,
  • Dolores Corella and ,
  • Jordi Salas-Salvadó,
  • M. Dolors Zomeño,
  • Manoli García-de-la-Hera,
  • Dora Romaguera,
  • J. Alfredo Martínez and
  • Alfredo Gea
  • + 32 authors+ 27 authors

4 November 2018

Inadequate diet influences chronic diseases such as cardiovascular disease (CVD), the leading cause of death in Spain. CVD figures vary from one geographical region to another; this could be associated with different food choices. Our aim was to anal...

  • Article
  • Open Access
40 Citations
10,694 Views
18 Pages

Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores

  • Dolores Corella,
  • Oscar Coltell,
  • Jose V. Sorlí,
  • Ramón Estruch and ,
  • Laura Quiles,
  • Miguel Ángel Martínez-González,
  • Jordi Salas-Salvadó,
  • Olga Castañer,
  • Fernando Arós and
  • José M. Ordovás
  • + 14 authors+ 9 authors

6 December 2016

Nutrigenetic studies analyzing gene–diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by obesity. Moreover, TCF7L2...

(This article belongs to the Special Issue Nutrigenetics)
  • Article
  • Open Access
56 Citations
9,939 Views
17 Pages

Dietary Diversity and Nutritional Adequacy among an Older Spanish Population with Metabolic Syndrome in the PREDIMED-Plus Study: A Cross-Sectional Analysis

  • Naomi Cano-Ibáñez,
  • Alfredo Gea,
  • Miguel A. Martínez-González,
  • Jordi Salas-Salvadó and ,
  • Dolores Corella,
  • M. Dolors Zomeño,
  • Dora Romaguera,
  • Jesús Vioque,
  • Fernando Aros and
  • Aurora Bueno-Cavanillas
  • + 45 authors+ 40 authors

26 April 2019

Dietary guidelines emphasize the importance of a varied diet to provide an adequate nutrient intake. However, an older age is often associated with consumption of monotonous diets that can be nutritionally inadequate, increasing the risk for the deve...

(This article belongs to the Special Issue Diet Diversity and Diet Quality)
  • Article
  • Open Access
221 Citations
20,573 Views
15 Pages

Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study

  • Ana Garcia-Arellano,
  • Raul Ramallal,
  • Miguel Ruiz-Canela,
  • Jordi Salas-Salvadó and ,
  • Dolores Corella,
  • Nitin Shivappa,
  • Helmut Schröder,
  • James R. Hébert,
  • Emilio Ros and
  • The PREDIMED Investigators
  • + 17 authors+ 12 authors

29 May 2015

Previous studies have reported an association between a more pro-inflammatory diet profile and various chronic metabolic diseases. The Dietary Inflammatory Index (DII) was used to assess the inflammatory potential of nutrients and foods in the contex...

(This article belongs to the Special Issue Nutrition and CVD)
  • Article
  • Open Access
10 Citations
5,201 Views
15 Pages

Deprivation Index and Lifestyle: Baseline Cross-Sectional Analysis of the PREDIMED-Plus Catalonia Study

  • Josep Basora,
  • Felipe Villalobos,
  • Meritxell Pallejà-Millán,
  • Nancy Babio and ,
  • Albert Goday,
  • María Dolores Zomeño,
  • Xavier Pintó,
  • Emilio Sacanella and
  • Jordi Salas-Salvadó
  • + 4 authors+ 0 author

27 September 2021

This baseline cross-sectional analysis from data acquired in a sub-sample of the PREDIMED-Plus study participants aimed to evaluate the relation between the Composite Socioeconomic Index (CSI) and lifestyle (diet and physical activity). This study in...

(This article belongs to the Special Issue Mediterranean Diet and Physical Activity as Healthy Lifestyles for Human Health)
  • Article
  • Open Access
4 Citations
4,265 Views
14 Pages

Association between the Potential Influence of a Lifestyle Intervention in Older Individuals with Excess Weight and Metabolic Syndrome on Untreated Household Cohabitants and Their Family Support: The PREDIMED-Plus Study

  • Josep Basora,
  • Felipe Villalobos,
  • Meritxell Pallejà-Millán,
  • Nancy Babio and ,
  • Albert Goday,
  • Olga Castañer,
  • Montserrat Fitó,
  • María Dolores Zomeño,
  • Xavier Pintó and
  • Jordi Salas-Salvadó
  • + 7 authors+ 2 authors

3 July 2020

This cross-sectional study aims to evaluate the association between the PREDIMED-Plus study lifestyle intervention and (i) adherence to the Mediterranean diet (MedDiet) and (ii) physical activity of cohabiting study participants, and to define the re...

(This article belongs to the Section Nutritional Epidemiology)
  • Article
  • Open Access
23 Citations
7,920 Views
13 Pages

Plasma Metabolites Associated with Coffee Consumption: A Metabolomic Approach within the PREDIMED Study

  • Christopher Papandreou,
  • Pablo Hernández-Alonso,
  • Mònica Bulló,
  • Miguel Ruiz-Canela and ,
  • Edward Yu,
  • Marta Guasch-Ferré,
  • Estefanía Toledo,
  • Courtney Dennis,
  • Amy Deik and
  • Jordi Salas-Salvadó
  • + 18 authors+ 13 authors

8 May 2019

Few studies have examined the association of a wide range of metabolites with total and subtypes of coffee consumption. The aim of this study was to investigate associations of plasma metabolites with total, caffeinated, and decaffeinated coffee cons...

  • Brief Report
  • Open Access
7 Citations
5,071 Views
12 Pages

Glycolysis Metabolites and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Trial

  • Nerea Becerra-Tomás,
  • Miguel Ruiz-Canela,
  • Pablo Hernández-Alonso,
  • Mònica Bulló and ,
  • Jun Li,
  • Marta Guasch-Ferré,
  • Estefanía Toledo,
  • Clary B. Clish,
  • Ramon Estruch and
  • Jordi Salas-Salvadó
  • + 17 authors+ 12 authors

The increased prevalence of atrial fibrillation (AF) and heart failure (HF) highlights the need to better understand the mechanisms underlying these cardiovascular diseases (CVDs). In the present study, we aimed to evaluate the association between gl...

(This article belongs to the Section Endocrinology and Clinical Metabolic Research)
  • Article
  • Open Access
21 Citations
8,847 Views
12 Pages

Modulation of Telomere Length by Mediterranean Diet, Caloric Restriction, and Exercise: Results from PREDIMED-Plus Study

  • María Fernández de la Puente,
  • Pablo Hernández-Alonso,
  • Silvia Canudas,
  • Amelia Marti and ,
  • Montserrat Fitó,
  • Cristina Razquin and
  • Jordi Salas-Salvadó
  • + 2 authors+ 0 author

12 October 2021

Telomere length (TL) has been associated with aging and is determined by lifestyle. However, the mechanisms by which a dietary pattern such as the Mediterranean diet (MedDiet) affects TL homeostasis are still unknown. Our aim was to analyse the effec...

(This article belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
  • Article
  • Open Access
148 Citations
16,437 Views
16 Pages

Validation of the English Version of the 14-Item Mediterranean Diet Adherence Screener of the PREDIMED Study, in People at High Cardiovascular Risk in the UK

  • Angeliki Papadaki,
  • Laura Johnson,
  • Zoi Toumpakari,
  • Clare England and ,
  • Manmita Rai,
  • Stu Toms,
  • Chris Penfold,
  • Itziar Zazpe,
  • Miguel A. Martínez-González and
  • Gene Feder
  • + 5 authors+ 0 author

28 January 2018

The aim of this study was to examine the validity of the English version of the PREvencion con DIetaMEDiterranea (PREDIMED) 14-item Mediterranean Diet Adherence Screener (MEDAS), a brief questionnaire assessing adherence to the Mediterranean diet (Me...

(This article belongs to the Special Issue Assessing the Mediterranean Diet in Public Health: Scoring Systems, Effects on Chronic Disease and Interventions)
  • Article
  • Open Access
16 Citations
6,188 Views
10 Pages

Fatty Acids Composition of Blood Cell Membranes and Peripheral Inflammation in the PREDIMED Study: A Cross-Sectional Analysis

  • Jananee Muralidharan,
  • Christopher Papandreou,
  • Aleix Sala-Vila,
  • Nuria Rosique-Esteban and ,
  • Montserrat Fitó,
  • Ramon Estruch,
  • Miguel Angel Martínez-González,
  • Dolores Corella,
  • Emilio Ros and
  • Monica Bulló
  • + 8 authors+ 3 authors

7 March 2019

There is limited evidence from epidemiological studies for the inflammatory or anti-inflammatory properties of fatty acids in blood cell membranes. Therefore, this study examined associations between baseline (n = 282) and 1-year (n = 143) changes in...

  • Article
  • Open Access
1 Citations
1,716 Views
13 Pages

Young Workers and Lifestyles in a Mediterranean Cultural Context: What Is the Contribution of Occupational Health Promotion?

  • Elpidio Maria Garzillo,
  • Anna Rita Corvino,
  • Giuseppe Porciello,
  • Daniele Guida and ,
  • Marco Spasiano,
  • Nadia Miraglia and
  • Monica Lamberti
  • + 2 authors+ 0 author

Adherence to a healthy diet and an active lifestyle is now a key component of workplace health promotion (WHP) programs. The primary objective of the study is the assessment of the need for the implementation of corrective WHP interventions aimed at...

(This article belongs to the Special Issue Healthy and Safe Environments across Occupational and Environmental Contexts)
  • Article
  • Open Access
31 Citations
9,726 Views
15 Pages

Association between the 2018 WCRF/AICR and the Low-Risk Lifestyle Scores with Colorectal Cancer Risk in the Predimed Study

  • Laura Barrubés,
  • Nancy Babio,
  • Pablo Hernández-Alonso,
  • Estefania Toledo and ,
  • Judith B. Ramírez Sabio,
  • Ramón Estruch,
  • Emilio Ros,
  • Montserrat Fitó,
  • Angel M Alonso-Gómez and
  • Jordi Salas-Salvadó
  • + 13 authors+ 8 authors

23 April 2020

Limited longitudinal studies have been conducted to evaluate colorectal cancer (CRC) incidence based on the updated 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) recommendations or other global lifestyle indices,...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
37 Citations
9,444 Views
10 Pages

Association between Eating Speed and Classical Cardiovascular Risk Factors: A Cross-Sectional Study

  • Indira Paz-Graniel,
  • Nancy Babio,
  • Ignacio Mendez and
  • Jordi Salas-Salvadó

4 January 2019

Cardiovascular disease (CVD) is one of the main causes of morbidity and mortality around the world. Lifestyle is recognized as a key factor in the development of metabolic disorders and CVD. Recently, eating speed has been of particular interest sinc...

  • Article
  • Open Access
3 Citations
3,431 Views
12 Pages

One-Year Changes in Urinary Microbial Phenolic Metabolites and the Risk of Type 2 Diabetes—A Case-Control Study

  • María Marhuenda-Muñoz,
  • Inés Domínguez-López,
  • Emily P. Laveriano-Santos,
  • Isabella Parilli-Moser and ,
  • Cristina Razquin,
  • Miguel Ruiz-Canela,
  • Francisco Javier Basterra-Gortari,
  • Dolores Corella,
  • Jordi Salas-Salvadó and
  • Rosa M. Lamuela-Raventós
  • + 14 authors+ 9 authors

8 August 2022

The intake of polyphenols has been associated with a risk reduction of type 2 diabetes. Nevertheless, to the best of our knowledge, the molecules that might be metabolically active after ingestion are only starting to be investigated regarding this m...

(This article belongs to the Special Issue Phytochemicals as Modulators of Oxidative Stress-Dependent, Inflammatory Conditions)
  • Article
  • Open Access
8 Citations
9,116 Views
14 Pages

High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma

  • María Marhuenda-Muñoz,
  • José Fernando Rinaldi de Alvarenga,
  • Álvaro Hernáez,
  • Anna Tresserra-Rimbau and ,
  • Miguel Ángel Martínez-González,
  • Jordi Salas-Salvadó,
  • Dolores Corella,
  • Mireia Malcampo,
  • José Alfredo Martínez and
  • Rosa M Lamuela-Raventós
  • + 47 authors+ 42 authors

Carotenoids are pigments contained mainly in fruit and vegetables (F&V) that have beneficial effects on cardiometabolic health. Due to their lipophilic nature, co-ingestion of fat appears to increase their bioavailability via facilitating transfe...

(This article belongs to the Special Issue Dietary Antioxidants in Mediterranean Diet)
  • Article
  • Open Access
49 Citations
7,476 Views
10 Pages

Type 2 Diabetes Is Associated with a Different Pattern of Serum Polyamines: A Case–Control Study from the PREDIMED-Plus Trial

  • Jose C. Fernandez-Garcia,
  • Antoni Delpino-Rius,
  • Iris Samarra,
  • Daniel Castellano-Castillo and ,
  • Araceli Muñoz-Garach,
  • Maria R. Bernal-Lopez,
  • Maria I. Queipo-Ortuño,
  • Fernando Cardona,
  • Bruno Ramos-Molina and
  • Francisco J. Tinahones
  • + 5 authors+ 0 author

10 January 2019

Objective: Polyamines are naturally occurring cationic molecules present in all living cells. Dysregulation of circulating polyamines has been reported in several conditions, but little is known about the levels of serum polyamines in chronic metabol...

(This article belongs to the Special Issue Type 2 Diabetes: Update on Pathophysiology and Treatment)
  • Article
  • Open Access
35 Citations
8,284 Views
21 Pages

Adherence to the Mediterranean Lifestyle and Desired Body Weight Loss in a Mediterranean Adult Population with Overweight: A PREDIMED-Plus Study

  • Cristina Bouzas,
  • Maria del Mar Bibiloni,
  • Alicia Julibert,
  • Miguel Ruiz-Canela and ,
  • Jordi Salas-Salvadó,
  • Dolores Corella,
  • Maria Dolors Zomeño,
  • Dora Romaguera,
  • Jesús Vioque and
  • Josep A. Tur
  • + 47 authors+ 42 authors

16 July 2020

Background. Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. Objectives. The aim of this study was to assess the association between the adherence to the Mediterranean lifest...

(This article belongs to the Section Nutritional Epidemiology)
  • Article
  • Open Access
68 Citations
12,917 Views
19 Pages

Polyphenol Levels Are Inversely Correlated with Body Weight and Obesity in an Elderly Population after 5 Years of Follow Up (The Randomised PREDIMED Study)

  • Xiaohui Guo,
  • Anna Tresserra-Rimbau,
  • Ramón Estruch,
  • Miguel A. Martínez-González and ,
  • Alexander Medina-Remón,
  • Montserrat Fitó,
  • Dolores Corella,
  • Jordi Salas-Salvadó,
  • Maria Puy Portillo and
  • Rosa M. Lamuela-Raventós
  • + 7 authors+ 2 authors

3 May 2017

Overweight and obesity have been steadily increasing in recent years and currently represent a serious threat to public health. Few human studies have investigated the relationship between polyphenol intake and body weight. Our aim was to assess the...

(This article belongs to the Special Issue Effects of Polyphenol-Rich Foods on Human Health)
  • Article
  • Open Access
87 Citations
11,272 Views
17 Pages

Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study

  • Sara Castro-Barquero,
  • Anna Tresserra-Rimbau,
  • Facundo Vitelli-Storelli,
  • Mónica Doménech and ,
  • Jordi Salas-Salvadó,
  • Vicente Martín-Sánchez,
  • María Rubín-García,
  • Pilar Buil-Cosiales,
  • Dolores Corella and
  • Ramon Estruch
  • + 50 authors+ 45 authors

4 March 2020

Dietary polyphenol intake is associated with improvement of metabolic disturbances. The aims of the present study are to describe dietary polyphenol intake in a population with metabolic syndrome (MetS) and to examine the association between polyphen...

(This article belongs to the Special Issue Dietary Polyphenols and Human Health)
  • Article
  • Open Access
9 Citations
4,379 Views
13 Pages

Serum Selenium and Incident Cardiovascular Disease in the PREvención con DIeta MEDiterránea (PREDIMED) Trial: Nested Case-Control Study

  • Mario Gutiérrez-Bedmar,
  • Fernando Gil,
  • Pablo Olmedo,
  • Miguel Ruiz-Canela and ,
  • Miguel Ángel Martínez-González,
  • Jordi Salas-Salvadó,
  • Nancy Babio,
  • Montserrat Fitó,
  • Jose Luís Del Val García and
  • Carlos Muñoz-Bravo
  • + 15 authors+ 10 authors

10 November 2022

Background: Selenium is an essential trace mineral with potential interest for cardiovascular disease (CVD) prevention owing to its antioxidant properties. Epidemiological data on selenium status and CVD remain inconsistent. The objective of this stu...

(This article belongs to the Special Issue Clinical Research on Nutritional Epidemiology)
  • Feature Paper
  • Article
  • Open Access
109 Citations
18,575 Views
20 Pages

Leisure-Time Physical Activity, Sedentary Behaviour and Diet Quality are Associated with Metabolic Syndrome Severity: The PREDIMED-Plus Study

  • Laura Gallardo-Alfaro,
  • Maria del Mar Bibiloni,
  • Catalina M. Mascaró,
  • Sofía Montemayor and ,
  • Miguel Ruiz-Canela,
  • Jordi Salas-Salvadó,
  • Dolores Corella,
  • Montserrat Fitó,
  • Dora Romaguera and
  • Josep A. Tur
  • + 47 authors+ 42 authors

7 April 2020

Healthy lifestyle factors, such as physical activity (PA) and Mediterranean diet (MD), decrease the likelihood of developing metabolic syndrome (MetS). The aim of this study was to report main lifestyle components and related factors according to the...

(This article belongs to the Special Issue Nutrition and Lifestyle for the Prevention of Type 2 Diabetes and Hypertension)
  • Article
  • Open Access
34 Citations
6,867 Views
9 Pages

Effectiveness of Mediterranean Diet Implementation in Dry Eye Parameters: A Study of PREDIMED-PLUS Trial

  • Ignacio Molina-Leyva,
  • Alejandro Molina-Leyva,
  • Blanca Riquelme-Gallego,
  • Naomi Cano-Ibáñez and ,
  • Laura García-Molina and
  • Aurora Bueno-Cavanillas
  • + 1 author+ 0 author

1 May 2020

The purpose of this study is to evaluate the effect of a Mediterranean diet supplemented with extra virgin olive oil and nuts on dry eye parameters. The participants in this study were randomized into one of the two interventional arms: (1) a standar...

(This article belongs to the Section Nutrition and Public Health)
  • Review
  • Open Access
119 Citations
25,417 Views
28 Pages

Nuts: Natural Pleiotropic Nutraceuticals

  • Emilio Ros,
  • Annapoorna Singh and
  • James H. O’Keefe

19 September 2021

Common nuts (tree nuts and peanuts) are energy-dense foods that nature has gifted with a complex matrix of beneficial nutrients and bioactives, including monounsaturated and polyunsaturated fatty acids, high-quality protein, fiber, non-sodium mineral...

(This article belongs to the Special Issue Nutraceutical Approaches to Cardiovascular and Metabolic Diseases: Evidence and Opportunities)
  • Article
  • Open Access
1 Citations
955 Views
17 Pages

Effect of Omega-3 Fatty Acid Intake on Circulating Biomarkers of Atrial Fibrillation-Related Pathways in the PREDIMED-Plus Study

  • Jaime Lara Moreno,
  • Linzi Li,
  • Alvaro Alonso,
  • Dora Romaguera and ,
  • Angel M. Alonso-Gómez,
  • Cristina Razquin,
  • Lucas Tojal-Sierra,
  • Miquel Fiol,
  • Miguel A. Martinez-Gonzalez and
  • Estefanía Toledo
  • + 8 authors+ 3 authors

23 May 2026

Background/Objectives: Whether habitual dietary omega-3 fatty acid intake is reflected in circulating biomarkers of atrial fibrillation (AF)-related pathways is unclear. We assessed whether usual dietary intake of n-3 fatty acids—considered as...

(This article belongs to the Special Issue Exploring the Role of Fatty Acids in Chronic Disease Development)
  • Article
  • Open Access
100 Citations
13,829 Views
17 Pages

Role of Nutrition and Adherence to the Mediterranean Diet in the Multidisciplinary Approach of Hidradenitis Suppurativa: Evaluation of Nutritional Status and Its Association with Severity of Disease

  • Luigi Barrea,
  • Gabriella Fabbrocini,
  • Giuseppe Annunziata,
  • Giovanna Muscogiuri and ,
  • Marianna Donnarumma,
  • Claudio Marasca,
  • Annamaria Colao and
  • Silvia Savastano
  • + 3 authors+ 0 author

28 December 2018

Hidradenitis suppurativa (HS) is a chronic, inflammatory and debilitating skin disorder. The exacerbating factors of HS include nutrition and adiposity. We aimed to investigate the relationships between body composition and the adherence to the Medit...

  • Article
  • Open Access
44 Citations
7,092 Views
21 Pages

Influence of the Mediterranean Diet on 25-Hydroxyvitamin D Levels in Adults

  • Luigi Barrea,
  • Giovanna Muscogiuri,
  • Daniela Laudisio,
  • Gabriella Pugliese and ,
  • Giulia de Alteriis,
  • Annamaria Colao and
  • Silvia Savastano
  • + 2 authors+ 0 author

16 May 2020

The Mediterranean diet (MD) is a dietary pattern effective in terms of prevention of obesity-related diseases, and represents the gold standard in preventive medicine, due to the synergistic action of many nutrients with antioxidant and anti-inflamma...

(This article belongs to the Special Issue The Role of Vitamin D in Chronic Diseases)
  • Article
  • Open Access
78 Citations
7,979 Views
14 Pages

Mediterranean Diet and Phase Angle in a Sample of Adult Population: Results of a Pilot Study

  • Luigi Barrea,
  • Giovanna Muscogiuri,
  • Paolo Emidio Macchia,
  • Carolina Di Somma and ,
  • Andrea Falco,
  • Maria Cristina Savanelli,
  • Annamaria Colao and
  • Silvia Savastano
  • + 3 authors+ 0 author

17 February 2017

The Mediterranean diet is a healthy dietary pattern known to actively modulate the cell membrane properties. Phase angle (PhA) is a direct measure by Bioelectrical Impedance Analysis (BIA) used as marker of cell membrane integrity. Both food behaviou...

  • Article
  • Open Access
39 Citations
7,496 Views
14 Pages

Effect of Adherence to a Mediterranean Diet and Olive Oil Intake during Pregnancy on Risk of Small for Gestational Age Infants

  • Juan Miguel Martínez-Galiano,
  • Rocío Olmedo-Requena,
  • Rocío Barrios-Rodríguez,
  • Carmen Amezcua-Prieto and ,
  • Aurora Bueno-Cavanillas,
  • Inmaculada Salcedo-Bellido,
  • Jose J. Jimenez-Moleon and
  • Miguel Delgado-Rodríguez
  • + 3 authors+ 0 author

5 September 2018

To quantify the effect of a Mediterranean dietary pattern, as well as the consumption of olive oil (OO), on the risk of having a small for gestational age infants (SGA), a matched case-control study was conducted in Spain. Dietary intake during pregn...

  • Article
  • Open Access
77 Citations
6,237 Views
18 Pages

Impact of Nutritional Status on Gastroenteropancreatic Neuroendocrine Tumors (GEP-NET) Aggressiveness

  • Luigi Barrea,
  • Barbara Altieri,
  • Giovanna Muscogiuri,
  • Daniela Laudisio and ,
  • Giuseppe Annunziata,
  • Annamaria Colao,
  • Antongiulio Faggiano and
  • Silvia Savastano
  • + 3 authors+ 0 author

1 December 2018

Neuroendocrine tumors (NETs) are rare neoplasms mostly originating from the gastroenteropancreatic tract (GEP-NETs). Data regarding nutritional status in GEP-NET patients are limited. The aim of the study was to investigate the nutritional status and...

  • Review
  • Open Access
34 Citations
18,357 Views
29 Pages

6 December 2019

The Mediterranean Diet (MD) is, culturally and historically, the nutritional pattern shared by people living in the olive-tree growing areas of the Mediterranean basin. It is of great importance for its potential preventive effect against cardiovascu...

(This article belongs to the Special Issue Selected Papers from NUTRIMAD 2018)
  • Article
  • Open Access
13 Citations
4,492 Views
14 Pages

Eating Right, Sleeping Tight? A Cross-Sectional Study on the Student-Athlete Paradox for Diet and Sleep Behaviors

  • Olga Papale,
  • Emanuel Festino,
  • Francesca Di Rocco,
  • Marianna De Maio and ,
  • Carl Foster,
  • Cristina Cortis and
  • Andrea Fusco
  • + 2 authors+ 0 author

12 September 2025

Background: Student-athletes face the dual challenge of balancing academic and athletic commitments, which may simultaneously promote healthy lifestyle habits while increasing psychosocial and physiological stressors, particularly among female studen...

(This article belongs to the Section Nutritional Epidemiology)
  • Article
  • Open Access
108 Views
14 Pages

Changes in Aerobic Capacity and Mediterranean Diet Adherence at Group and Individual Levels During Cardiac Rehabilitation

  • Adrian Lopez-Cava,
  • Arturo Martinez-Rodrigo,
  • Laura Núñez-Martínez and
  • Susana Priego-Jiménez

30 October 2026

Cardiac rehabilitation (CR) combines supervised exercise with interventions targeting long-term health behaviours, yet outcomes are often evaluated primarily through changes in aerobic capacity. This study compared the standardised magnitude of impro...

(This article belongs to the Special Issue Fifth Anniversary of "Biomedical Engineering" Section—Recent Advances in Biomedical Engineering)
  • Article
  • Open Access
96 Citations
11,763 Views
11 Pages

Sleep Quality in Obesity: Does Adherence to the Mediterranean Diet Matter?

  • Giovanna Muscogiuri,
  • Luigi Barrea,
  • Sara Aprano,
  • Lydia Framondi and ,
  • Rossana Di Matteo,
  • Daniela Laudisio,
  • Gabriella Pugliese,
  • Silvia Savastano and
  • Annamaria Colao
  • + 4 authors+ 0 author

10 May 2020

Obesity and unhealthy eating habits have been associated with sleep disturbances (SD). The Mediterranean diet (MD) is a healthy nutritional pattern that has been reported to be associated with better health and sleep quality. Thus, the aim of the stu...

(This article belongs to the Special Issue Diet, Nutrition and Chronic Degenerative Diseases)
  • Article
  • Open Access
4 Citations
1,241 Views
12 Pages

Oxidative Stress and Endothelial Dysfunction in Patients with Hypertensive Nephropathy: Role of the Mediterranean Diet

  • Luca Salomone,
  • Danilo Menichelli,
  • Irene Azzara,
  • Pierluigi Maria Damosso and ,
  • Vittoria Cammisotto,
  • Valentina Castellani,
  • Pasquale Pignatelli,
  • Elena Pacella,
  • Anna Paola Mitterhofer and
  • Silvia Lai
  • + 6 authors+ 1 author

28 January 2026

Essential hypertension is a leading cause of chronic kidney disease (CKD) and is frequently complicated by hypertensive nephropathy, characterized by nephroangiosclerosis and increased intrarenal vascular resistance, assessable by renal resistive ind...

(This article belongs to the Special Issue Nutrition, Inflammation, and Chronic Kidney Disease)
  • Article
  • Open Access
11 Citations
7,912 Views
19 Pages

The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome

  • Alba Marcos-Delgado,
  • Tania Fernández-Villa,
  • Miguel Ángel Martínez-González,
  • Jordi Salas-Salvadó and ,
  • Dolores Corella,
  • Olga Castañer,
  • J. Alfredo Martínez,
  • Ángel M. Alonso-Gómez,
  • Julia Wärnberg and
  • Vicente Martín
  • + 44 authors+ 39 authors

The main objective of this study was to examine the relationship between the level of physical activity (PA) and the degree of obesity with health-related quality of life (HRQoL) in individuals with metabolic syndrome (MetS) who participated in the P...

(This article belongs to the Special Issue Assessment of Health-Related Quality of Life (HRQoL) in Public Health)
  • Article
  • Open Access
922 Views
17 Pages

Sleep Quality and Adherence to the Mediterranean Diet in Male Young Adults: An Exploratory Study Among Amateur Soccer Players, Physically Active Individuals, and Individuals with High Sitting Time

  • Emanuel Festino,
  • Olga Papale,
  • Francesca Di Rocco,
  • Silvia Zema and ,
  • Marianna De Maio,
  • Paulo Roberto dos Santos Amorim,
  • Carl Foster,
  • Alessandra Amato,
  • Patrizia Proia and
  • Andrea Fusco
  • + 6 authors+ 1 author

17 September 2026

Amateur soccer players represent a relatively understudied population and often combine training with study or work, facing daily challenges that can impact sleep, diet, and circadian-related behaviors. Since these factors are important for health, r...

(This article belongs to the Special Issue Advances in Football Science: Integrating Technology, Performance, and Well-Being (2nd Edition))
  • Article
  • Open Access
11 Citations
4,027 Views
14 Pages

16 January 2025

Background: The research on orthorexia nervosa (ON) has thoroughly outlined the connection between it and various mental disorders, including obsessive-compulsive disorders and eating disorders, in addition to stress. However, research has not consid...

(This article belongs to the Special Issue Bidirectional Link between Eating Habits, Lifestyle, Physical Exercise and Depression and Other Mental Disorders)
  • Article
  • Open Access
907 Views
19 Pages

An Innovative, Multimedia-Based Intervention for Promoting Changes in Lifestyle in Italian Families

  • Iolanda Chinellato,
  • Annamaria Acquaviva,
  • Mary Lista,
  • Loreto Nemi and ,
  • Eva Da Ros,
  • Benedetta Morlupi,
  • Manuela Maione,
  • Renata Carraro,
  • Laura Lodi and
  • Francesca Poggiante
  • + 10 authors+ 5 authors

1 September 2026

Background/Objectives: Several studies have reported a high prevalence of overweight and obesity among children and adults, with relevant implications for long-term health. Digital platforms and social media may support nutrition education when their...

(This article belongs to the Special Issue A Life-Course Approach to Healthy Dietary Lifestyles for the Prevention of Non-Communicable Diseases)
  • Article
  • Open Access
7 Citations
2,596 Views
13 Pages

Influence of Adherence to the Mediterranean Diet and Level of Physical Activity with Liver Steatosis in People Aged > 50 Years and with a BMI > 25 kg/m2: Association with Biochemical Markers

  • Laura Cano-Lallave,
  • Jaime Ruiz-Tovar,
  • Lucia Martin-de-Bernardo,
  • Malena Martinez-Oribe and ,
  • Cristina Rodriguez-Obispo,
  • Sara Carrascosa-Corrochano,
  • Ana Martín-Nieto,
  • Isabel Baeza,
  • Marta Gonzalez-Ramos and
  • Isabel Olazabal
  • + 6 authors+ 1 author

23 June 2024

Background: The main objective of this study is to determine the accuracy of different biochemical markers of hepatic steatosis and to correlate liver steatosis with adherence to the Mediterranean diet and level of physical activity. Methods: A cross...

(This article belongs to the Special Issue The Role of Nutrition in Applied Physiology)
  • Article
  • Open Access
24 Citations
5,597 Views
12 Pages

Prevalence of Sarcopenia and Dynapenia and Related Clinical Outcomes in Patients with Type 1 Diabetes Mellitus

  • María Carmen Andreo-López,
  • María Teresa Zarco-Martín,
  • Victoria Contreras-Bolívar and
  • María Luisa Fernández-Soto

24 November 2023

Background: Sarcopenia has recently been recognized as a complication of diabetes. However, there are few results about the prevalence of sarcopenia and dynapenia and the related clinical outcomes in type 1 diabetes mellitus (T1DM). Our objectives we...

(This article belongs to the Special Issue Nutritional Intervention on Diabetes and Muscle: From the Assessment to Treatment)
  • Article
  • Open Access
36 Citations
11,327 Views
10 Pages

The Mediterranean Diet: Effects on Insulin Resistance and Secretion in Individuals with Overweight or Obesity

  • Claudia Vetrani,
  • Ludovica Verde,
  • Annamaria Colao,
  • Luigi Barrea and
  • Giovanna Muscogiuri

25 October 2023

High adherence to the Mediterranean Diet (MD) is associated with a lower risk of type 2 diabetes. However, it is less clear whether the different MD food items might influence specific biological functions related to glucose tolerance, i.e., insulin...

(This article belongs to the Special Issue Insulin Resistance and Related Diseases: From Pathophysiology to Clinical Management)
  • Abstract
  • Open Access
1 Citations
5,305 Views
2 Pages

Effect of an Energy-Restricted Mediterranean Diet, Physical Activity and Behavioral Support Lifestyle Intervention on Body Composition in Older Adults with Metabolic Syndrome: Three-Year Results of the PREDIMED-Plus Trial

  • Dora Romaguera,
  • Miguel Ruiz-Canela,
  • J. Alfredo Martínez,
  • Vicente Martín and ,
  • Ramón Estruch,
  • Jordi Salas-Salvadó and
  • Jadwiga Konieczna
  • + 2 authors+ 0 author

Background and objectives: Large and long-term randomized controlled trials (RCT) that test the effect of a weight-loss lifestyle intervention on the changes in the directly quantified body composition are scarce. Here, we aimed to evaluate the effec...

(This article belongs to the Proceedings of The 14th European Nutrition Conference FENS 2023)
  • Article
  • Open Access
265 Citations
42,370 Views
21 Pages

Adherence to the Mediterranean Diet, Dietary Patterns and Body Composition in Women with Polycystic Ovary Syndrome (PCOS)

  • Luigi Barrea,
  • Angela Arnone,
  • Giuseppe Annunziata,
  • Giovanna Muscogiuri and ,
  • Daniela Laudisio,
  • Ciro Salzano,
  • Gabriella Pugliese,
  • Annamaria Colao and
  • Silvia Savastano
  • + 4 authors+ 0 author

23 September 2019

Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder and is characterized by chronic anovulation, hyperandrogenism, and polycystic ovaries. Obesity, low-grade chronic inflammatory status, and insulin-resistance (IR) often coe...

  • Article
  • Open Access
3 Citations
2,461 Views
16 Pages

Physical Activity Time, Alcohol Consumption, Mediterranean Diet, and Anxiety in Education Science Students

  • Daniel Sanz-Martín,
  • Félix Zurita-Ortega,
  • Eduardo Melguizo-Ibáñez,
  • José Manuel Alonso-Vargas and ,
  • Rafael Caracuel-Cáliz and
  • José Luis Ubago-Jiménez
  • + 1 author+ 0 author

Student lifestyles change during university. This research aimed to classify university students according to their levels of physical activity, alcohol consumption, adherence to the Mediterranean diet, and anxiety and studied the relationships betwe...

  • Article
  • Open Access
37 Citations
6,877 Views
10 Pages

Adherence to a Mediterranean Diet and Thyroid Function in Obesity: A Cross-Sectional Apulian Survey

  • Roberta Zupo,
  • Fabio Castellana,
  • Francesco Panza,
  • Luisa Lampignano and ,
  • Isanna Murro,
  • Carmen Di Noia,
  • Vincenzo Triggiani,
  • Gianluigi Giannelli,
  • Rodolfo Sardone and
  • Giovanni De Pergola
  • + 5 authors+ 0 author

16 October 2020

Much research suggests that Mediterranean eating habits and lifestyle contribute to counteract the risk of chronic diseases while promoting longevity, but little information is available on the effects of the Mediterranean diet (Med-Diet) on thyroid...

(This article belongs to the Special Issue Diet, Obesity, Type 2 Diabetes and Hypertension)
  • Communication
  • Open Access
17 Citations
7,283 Views
10 Pages

Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk

  • Christopher Papandreou,
  • Nancy Babio,
  • Andrés Díaz-López,
  • Miguel Á. Martínez-González and ,
  • Nerea Becerra-Tomas,
  • Dolores Corella,
  • Helmut Schröder,
  • Dora Romaguera,
  • Jesús Vioque and
  • Jordi Salas-Salvadó
  • + 47 authors+ 42 authors

1 April 2019

The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overwei...

  • Abstract
  • Open Access
2,072 Views
2 Pages

Development and Validation of Nutri S-Can, a Short Screener to Evaluate Adherence to the 2018 WCRF/AICR Cancer Prevention Recommendations

  • Alice Chaplin,
  • Mar Nafría,
  • Albert Sesé,
  • Elena Rayó and ,
  • Marga Morey,
  • Lara Prohens and
  • Dora Romaguera
  • + 2 authors+ 0 author

There is a lack of rapid dietary assessment tools to screen for compliance with guidelines for cancer prevention, such as those issued by the World Cancer Research Fund and the American Institute for Cancer Research. Our aim was to develop and valida...

(This article belongs to the Proceedings of The 14th European Nutrition Conference FENS 2023)

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