Nutrition, Inflammation, and Chronic Kidney Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 40
Special Issue Editor
2. Graduate Program in Biological Sciences—Physiology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-853, Brazil
Interests: chronic kidney disease; Inflammation; oxidative stress; gut microbiota; nutrition and bioactive compounds in food
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Patients with chronic kidney disease (CKD) face several factors that contribute to increased inflammation, including oxidative stress, metabolic acidosis, proteinuria, infections, changes in adipose tissue metabolism, and gut dysbiosis. The inflammatory condition in CKD is marked by the abnormal activation of the innate immune system, which ultimately leads to the signaling of various inflammatory pathways, such as nuclear factor kappa B (NF-κB), toll-like receptor 4 (TLR4), and nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 (NLRP3). The primary consequence of this inflammatory state includes disease progression, renal fibrosis, the onset of cardiovascular diseases, and increased mortality in this population. In this context, several non-pharmacological strategies are essential for modulating this condition in CKD. Among these strategies, the notion of food as medicine has gained prominence, as the nutrients and bioactive compounds in food can influence inflammatory pathways in CKD. Therefore, this Special Issue aims to explore areas related to the use of nutrients, bioactive compounds from food, or dietary patterns that modulate the inflammatory condition in CKD. Submissions of narrative review manuscripts, systematic reviews, and original manuscripts will be accepted.
This Special Issue is supervised by Prof. Dr. Denise Mafra, assisted by our Guest Editor's Assistant Editor Prof. Dr. Karen Salve Coutinho-Wolino (Graduate Program in Biological Sciences-Physiology, Federal University of Rio de Janeiro ).
Prof. Dr. Denise Mafra
Guest Editor
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Keywords
- chronic kidney disease
- inflammation
- nutrients
- bioactive compounds
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