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Open AccessArticle

Effectiveness of Mediterranean Diet Implementation in Dry Eye Parameters: A Study of PREDIMED-PLUS Trial

1
Department of Ophthalmology, Hospital Virgen de las Nieves, 18014 Granada, Spain
2
Department of Dermatology, Hospital Virgen de las Nieves, 18014 Granada, Spain
3
Department of Preventive Medicine and Public Health, Universidad de Granada, 18016 Granada, Spain
4
Instituto de Investigación Biosanitaria de Granada IBS, 18012 Granada, Spain
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(5), 1289; https://doi.org/10.3390/nu12051289
Received: 5 March 2020 / Revised: 27 April 2020 / Accepted: 28 April 2020 / Published: 1 May 2020
(This article belongs to the Section Nutrition and Public Health)
The purpose of this study is to evaluate the effect of a Mediterranean diet supplemented with extra virgin olive oil and nuts on dry eye parameters. The participants in this study were randomized into one of the two interventional arms: (1) a standard intervention group, a Mediterranean diet supplemented with extra virgin olive oil and nuts; and (2) an intensive intervention group, based on a hypocaloric Mediterranean diet and an intensive lifestyle program with physical activity and weight-loss goals. In both groups, common dry eye tests were conducted at baseline and after six months: the Ocular Surface Disease Index (OSDI), the Dry Eye Scoring System (DESS), tear break-up time (TBUT), the Schirmer’s test, and the Oxford staining grade. Sixty-seven eyes were examined. After six months, dry eye parameters improved in both groups; differences between groups were favorable for the intensive intervention group. The implementation of a Mediterranean diet pattern was beneficial for the selected patients with dry eye, and could be beneficial for patients with dry eye in general. Behavioral support for diet adherence and the promotion of healthy lifestyles (exercise) and weight loss (calorie restriction) have an added positive effect. View Full-Text
Keywords: mediterranean diet; dry eye; fatty acids; extra virgin olive oil; PREDIMED-PLUS trial mediterranean diet; dry eye; fatty acids; extra virgin olive oil; PREDIMED-PLUS trial
MDPI and ACS Style

Molina-Leyva, I.; Molina-Leyva, A.; Riquelme-Gallego, B.; Cano-Ibáñez, N.; García-Molina, L.; Bueno-Cavanillas, A. Effectiveness of Mediterranean Diet Implementation in Dry Eye Parameters: A Study of PREDIMED-PLUS Trial. Nutrients 2020, 12, 1289. https://doi.org/10.3390/nu12051289

AMA Style

Molina-Leyva I, Molina-Leyva A, Riquelme-Gallego B, Cano-Ibáñez N, García-Molina L, Bueno-Cavanillas A. Effectiveness of Mediterranean Diet Implementation in Dry Eye Parameters: A Study of PREDIMED-PLUS Trial. Nutrients. 2020; 12(5):1289. https://doi.org/10.3390/nu12051289

Chicago/Turabian Style

Molina-Leyva, Ignacio; Molina-Leyva, Alejandro; Riquelme-Gallego, Blanca; Cano-Ibáñez, Naomi; García-Molina, Laura; Bueno-Cavanillas, Aurora. 2020. "Effectiveness of Mediterranean Diet Implementation in Dry Eye Parameters: A Study of PREDIMED-PLUS Trial" Nutrients 12, no. 5: 1289. https://doi.org/10.3390/nu12051289

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