Special Issue "Dietary Antioxidants in Mediterranean Diet"

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Natural and Synthetic Antioxidants".

Deadline for manuscript submissions: 31 January 2021.

Special Issue Editors

Dr. Vlasios Goulas

Guest Editor
Department of Agricultural Sciences, Biotechnology and Food Science, Cyprus University of Technology, Limassol, Cyprus
Dr. Alexandra Barbouti

Guest Editor
Alexandra Barbouti, Assistant Professor, Laboratory of Anatomy-Histology-Embryology, Faculty of Medicine, University of Ioannina, Ioannina, Greece
Interests: redox signaling; oxidative stress; antioxidants; iron homeostasis; labile iron; apoptotic cell death; cellular senescence

Special Issue Information

Dear Colleagues,

Extensive epidemiological, clinical, and experimental data associate the Mediterranean diet with protection against chronic diseases (e.g. cardiovascular disease, cancer, and neurodegenerative diseases) and increased longevity. The Mediterranean diet is characterized by high amounts of olive oil and frequent consumption of fruits, vegetables, whole grains, legumes, and aromatic herbs. Since oxidative stress has been linked with numerous pathological conditions, it is proposed that the beneficial effects of the Mediterranean diet are due to the wide variety of dietary antioxidants, such as vitamins C and E, carotenoids, (poly)phenols, and minerals, that it provides. Consequently, several molecular mechanisms of action of dietary antioxidants have been proposed in an attempt to shed some light on the preventive effect of the Mediterranean diet.

Contributions to this Special Issue may cover all research aspects related to the characterization of antioxidant compositions of Mediterranean plant foods, the bioavailability and bioaccessibility of dietary antioxidants, In Vitro and In Vivo methods for the assessment of antioxidant potency of the Mediterranean diet’s components, state-of-the-art techniques to determine the contribution of dietary compounds to antioxidant intake, and the mechanisms of action of dietary antioxidants in disease prevention.

Dr. Vlasios Goulas
Dr. Alexandra Barbouti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polyphenols
  • bioactive compounds
  • chromatographic and spectroscopic techniques
  • structural elucidation of antioxidants
  • in vivo and in vitro antioxidant activity
  • high resolution antioxidant screening techniques
  • mechanism(s) of action of antioxidants
  • oxidative stress
  • reactive oxygen species
  • oxidative stress -related diseases
  • mediterranean diet

Related Special Issues

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Open AccessArticle
Chemical Characterization and Bioactivity of Extracts from Thymus mastichina: A Thymus with a Distinct Salvianolic Acid Composition
Antioxidants 2020, 9(1), 34; https://doi.org/10.3390/antiox9010034 - 31 Dec 2019
Cited by 6
Abstract
Thymus mastichina, also called mastic thyme or Spanish marjoram, is endemic to the Iberian Peninsula, where it is widely used in folk medicine especially for treating digestive and respiratory systems disorders, and as a condiment to season olives. This work describes for [...] Read more.
Thymus mastichina, also called mastic thyme or Spanish marjoram, is endemic to the Iberian Peninsula, where it is widely used in folk medicine especially for treating digestive and respiratory systems disorders, and as a condiment to season olives. This work describes for the first time the detailed phenolic composition of exhaustive hydroethanolic extracts and aqueous decoctions of Thymus mastichina. Unlike other species of the Thymus genera, Thymus mastichina extracts contain high amounts of salvianolic acid derivatives, with salvianolic acid A isomer being the main derivative. This isomer was identified in extracts from Thymus mastichina for the first time. Also, an undescribed salvianolic acid derivative in Thymus mastichina was identified and its structure was tentatively described. Extracts from Thymus mastichina showed significant scavenging activity of 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radical cation, hydroxyl, and nitric oxide radicals. The anti-proliferative effect of both T. mastichina extracts were tested against Caco-2 and HepG2 cells; the hydroethanolic extract showed a high anti-proliferative activity against Caco-2 cells compared to HepG2 cells (at 24 h exposure, the concentration that inhibits 50% of proliferation, IC50, was 71.18 ± 1.05 µg/mL and 264.60 ± 11.78 µg/mL for Caco-2 and HepG2, respectively). Thus, these results make this species a promising candidate for further investigation of its anti-tumoral potential. Therefore, Thymus mastichina can be potentially used as a functional food (used as a decoction or herbal tea) or as a source of bioactive ingredients with antioxidant and anti-proliferative properties. Full article
(This article belongs to the Special Issue Dietary Antioxidants in Mediterranean Diet)
Show Figures

Figure 1

Open AccessArticle
Use of Sieving as a Valuable Technology to Produce Enriched Buckwheat Flours: A Preliminary Study
Antioxidants 2019, 8(12), 583; https://doi.org/10.3390/antiox8120583 - 25 Nov 2019
Cited by 1
Abstract
Fractionation processes based on physical separation are a good strategy to produce enriched cereal flours. Therefore, the aim of this work is to evaluate the suitability of sieving of buckwheat flours to produce protein and phenolic (especially rutin) enriched fractions. Because of that, [...] Read more.
Fractionation processes based on physical separation are a good strategy to produce enriched cereal flours. Therefore, the aim of this work is to evaluate the suitability of sieving of buckwheat flours to produce protein and phenolic (especially rutin) enriched fractions. Because of that, dehulled whole buckwheat flour (GSTQ) was sieved obtaining fractions with a particle size of 215 µm, 160 µm, 85 µm, and 45 µm (GS215, GS160, GS85, and GS45). For that purpose, the determination of protein, ash, and total starch content and free and bound phenolic compounds was carried out. The highest content of total phenolic compounds was obtained in GS215 (3118.84 mg kg−1 d.w.), followed by GS160 (2499.11 mg kg−1 d.w.), GS85 (989.46 mg kg−1 d.w.), GSTQ (983.15 mg kg−1 d.w.), and GS45 (481.31 mg kg−1 d.w.). Therefore, the phenolic content decreased with the particle size decrease from 215 µm to 45 µm. Besides, there were no significant differences between the total phenolic content in GS85 and GSTQ. The fraction with 215 µm reported the highest protein and mineral salt content and presented rutin amounts four times higher than GSTQ. Full article
(This article belongs to the Special Issue Dietary Antioxidants in Mediterranean Diet)
Show Figures

Graphical abstract

Back to TopTop