Oncogenic fusion protein RUNX1-ETO is the product of the t(8;21) translocation, responsible for the most common cytogenetic subtype of acute myeloid leukemia. RUNX1, a critical transcription factor in hematopoietic development, is fused with almost t...
The obligatory path towards a lean manufacturing organization requires assessment and monitoring. However, a lean assessment framework is not yet available for the engineer to order (ETO) scenario. This work explored ten lean ETO maturity principles—...
The AML1-ETO (RUNX1-RUNX1T1) fusion gene created by the chromosome translocation t(8;21) (q21;q22) is one of the essential contributors to leukemogenesis. Only a few studies in the literature have focused on fusion gene-derived circular RNAs (f-circR...
Engineer-to-order (ETO) is a currently popular production model that can meet customers’ individual needs, for which the orders are primarily non-standard parts or small batches. This production model has caused many management challenges, incl...
Reference evapotranspiration (ETo) refers to the combined processes of evaporation and transpiration, which are relevant for hydrology, climate change research, and irrigation system design. The ETo is considered for different climatological studies,...
Neuroblastoma (NB) is a childhood cancer, commonly treated with drugs, such as etoposide (ETO), whose efficacy is limited by the onset of resistance. Here, aiming at identifying new treatments for chemo-resistant NB, the effects of two synthesized im...
The aim of this study is to determine the effect of climate change on reference evapotranspiration (ETo) and sunflower and wheat evapotranspiration (ETs and ETw, respectively) in the Trakya Region of Türkiye. ETo Calculator (version 3.2) and CRO...
Ethylene oxide (EtO) is a colorless, flammable gas at room temperature produced by the catalytic oxidation of ethylene. EtO is widely used by medical sterilization facilities to clean medical supplies and equipment. Recent epidemiological studies sho...
Climate change has been shown to directly influence evapotranspiration, which is one of the crucial watershed processes. The common approach to its calculation is via mathematical equations, such as 1985 Hargreaves-Samani (HS85). It computes referenc...
Extended trochanteric osteotomy (ETO) is an established method in revision total hip arthroplasty. Proximal migration of the greater trochanter fragment and the resulting non-union of the osteotomy remains a major problem, and several techniques have...
Acute myeloid leukemia (AML) is a heterogenous disease with multiple sub-types which are defined by different somatic mutations that cause blood cell differentiation to go astray. Mutations occur in genes encoding members of the cellular machinery co...
This study focuses on the role played by the work of Leo Tolstoy (1828–1910) in shaping socialism and agrarian-Buddhist utopianism in Japan. As Japanese translations of Tolstoy’s fiction and philosophy, and accounts of his life became mor...
DNA double-strand breaks (DSBs) represent one of the most severe forms of genetic damage in organisms, yet vertebrate models capable of monitoring DSBs in real-time remain scarce. BRCA1/BRCA2-containing complex subunit 3 (BRCC3), also known as BRCC36...
Reference evapotranspiration (ETo) estimation is essential for water resources management. The present research compares four different ETo estimators based on reanalysis data (ERA5-Land) and in situ observations from three different cultivation site...
This article scientifically studies the direct impact of climate problems on the time transition of reference crop evapotranspiration in the Xinjiang Autonomous Region of China from 1957 to 2017, which is conducive to formulating irrigation schedulin...
Reference evapotranspiration (ETo) estimations may be used to improve the efficiency of irrigated agriculture. However, its computation can be complex and could require numerous weather data that are not always available for many locations. Different...
The increased usage of high-throughput technologies in cancer research, including genetic and drug screens, generates large sets of candidate targets that need to be functionally validated for their roles in tumor development. Thus, reliable and robu...
This study employs advanced structural characterization techniques, including anomalous small-angle X-ray scattering (ASAXS), small-angle X-ray scattering (SAXS), and X-ray photoelectron spectroscopy (XPS), to investigate erbium (Er3+)-doped silica-b...
Reference evapotranspiration (ETo) is a key agrometeorological index for rational irrigation management. The standard method for ETo estimation, proposed by the FAO, is based on a complicated Penman–Monteith equation and requires many meteorolo...
The ability to offer customisation has been considered as a competitive advantage for industrialised house building (IHB) companies. Product platform approaches have been acknowledged as one of the prominent ways to improve both internal and external...
Reference evapotranspiration (ETo) is an important part of the water cycle, essential for climate studies, water resource management, and agricultural planning. However, accurate estimation of ETo is challenging when meteorological data are insuffici...
Ethosomes® have been proposed as potential intra-articular drug delivery devices, in order to obtain a longer residence time of the delivered drug in the knee joint. To this aim, the conventional composition and preparation method were modified. Etho...
Crop coefficient (Kc), the ratio of crop evapotranspiration (ETc) to reference evapotranspiration (ETo), is used to schedule an efficient irrigation regime. This research was conducted to investigate variations in ETc and growth-stage-specific Kc in...
The engineer-to-order (ETO) production strategy plays an important role in today’s manufacturing industry. This paper studies integrated multi-project scheduling and hierarchical workforce allocation in the assembly process of ETO products. The...
Based on the fervor and devotion of the Virgin of the Girdle of Tortosa—which gained a strong establishment from the 17th century onwards—this article explores the possibility of a cause-effect relationship between the apparition of the V...
The amount of water allocated to irrigation systems is significantly greater than the amount allocated to other sectors. Thus, irrigation water demand management is at the center of the attention of the Ministry of Agriculture and Forestry in Turkey....
At the moment, many engineer-to-order manufacturers are under pressure, the overcapacity in many sectors erodes prices and many companies, especially in Europe have gone into recent years in bankruptcy. Due to the increasing competition as well as th...
Resistance to chemotherapy is a major challenge to improving overall survival in Acute Myeloid Leukemia (AML). Therefore, the development of innovative therapies and the identification of more novel agents for AML are urgently needed. Celastrol, a co...
The present study develops ArcMap models to implement the following three methods: FAO-56 Penman–Monteith (FAO PM), Hargreaves–Samani (HS) and Hansen, with the former used as a reference. Moreover, three models implementing statistical indices (RMSD,...
The ability to predict the volume of methane outbursts in coal mines is critical for the prevention of methane outburst accidents and the assurance of coal-mine safety. This paper’s central argument is that existing prediction models are limite...
Acute myeloid leukemia (AML) is one of the most frequent, complex, and heterogeneous hematological malignancies. AML prognosis largely depends on acquired cytogenetic, epigenetic, and molecular abnormalities. Despite the improvement in understanding...
Acute myeloid leukemia (AML) is a complex disease with an aggressive clinical course and high mortality rate. The standard of care for patients has only changed minimally over the past 40 years. However, potentially useful agents have moved from benc...
Etoposide (ETO) has been used in treating adrenocortical tumor (ACT) cells. Our previous study showed that ETO inhibits ACT cell growth. In the present study, we show that ETO treatment at IC50 (10 μM) inhibited ACT cell growth by inducing cellular s...
Potential evapotranspiration (ETp) and reference crop evapotranspiration (ETo) are two key parameters in hydrology, meteorology, and agronomy. ETp and ETo are related to each other but have different meanings and applications. In this study, the ETp...
Background: This study sought to compare the results of two-stage revision total hip arthroplasty (THA) for periprosthetic infection (PJI) in patients with and without the use of an extended trochanteric osteotomy (ETO) for removal of a well-fixed fe...
This study aims at assessing the accuracy of estimating daily reference evapotranspiration (ETo) computed with NASA POWER reanalysis products. Daily ETo estimated from local observations of weather variables in 14 weather stations distributed across...
Understanding the trends of reference evapotranspiration (ETo) and its influential meteorological variables due to climate change is required for studying the hydrological cycle, vegetation restoration, and regional agricultural production. Although...
Spatiotemporal variations in reference evapotranspiration (ETo) are sensitive to the meteorological data used in its estimation. The sensitivity of the ASCE standardized ETo equation to meteorological variables from GOES-PRWEB dataset was evaluated f...
Reference crop evapotranspiration (ETo) plays a role in irrigation advisory being of crucial importance for water managers dealing with scarce water resources. Following the ETo definition, it can be shown that total solar radiation is the main drive...
Reference evapotranspiration (ETo) is an effective measure of atmospheric water demand of the land surface. In-depth investigations of the relationship between ETo and primary climatic factors can facilitate the adaptable agriculture and optimize wat...
Accurate estimation of reference evapotranspiration (ETo) plays a vital role in irrigation and water resource planning. The Penman–Monteith method recommended by the Food and Agriculture Organization (FAO PM56) is widely used and considered a s...
The aim of this study was to improve the solubility of etoposide–ethylcellulose (ET–ETO) microparticles using the freeze-drying technique. Ethylcellulose (EC) microparticles loaded with etoposide (ETO) were prepared with different drug–polymer molar...
A correct determination of irrigation water requirements necessitates an adequate estimation of reference evapotranspiration (ETo). In this study, monthly ETo is estimated using artificial neural network (ANN) models. Eleven combinations of long-term...
Based on the meteorological data from 46 stations in the Hai River Basin (HRB) from 1961–2010, the annual and seasonal variation of reference evapotranspiration was analyzed. The sensitivity coefficients combined with the detrend method were used to...
Background: Stem revisions in revision total hip arthroplasty (THA) with proximal bone stock loss may be dealt with utilizing modular, uncemented conical stems. During stem extraction, surgeons may resort to extended trochanteric osteotomy (ETO). How...
Etoposide (ETO) is a cytotoxic drug that exerts its effect by increasing reactive oxygen species (ROS) production. Although ETO is widely used, fast metabolism, poor solubility, systemic toxicity, and multi-drug resistance induction all limit its adm...
Estimation of reference evapotranspiration (ETo) is a key element in water resources management and crop water requirement which, in turn, affects irrigation scheduling. ETo is subject to the influence of various climatic parameters including minimum...
The Food and Agricultural Organization of the United Nations (FAO) Penman–Monteith (PM) method is widely regarded as the most effective reference evapotranspiration (ETo) estimator; however, it requires a wide range of data that may be scarce i...
29 May 2025
Ethylene oxide (EtO) gas is a widely used industrial chemical and known health hazard. Multiple studies have determined that EtO exposure can be measured via hemoglobin adduct levels, and EtO exposure increases the risk of cancer and neurocognitive d...
The accurate estimation of reference crop evapotranspiration (ETO) plays an important role in guiding regional water resource management and crop water content research. In order to improve the accuracy of ETO prediction in regions with missing data,...
of 7