Carrion’s disease, caused by infection with the bacterium Bartonella bacilliformis (B. bacilliformis), is effectively treated with antibiotics, but reaches fatality rates of ~90% if untreated. Current diagnostic methods are limited, insuff...
Beijing’s One Million Mu Plain Afforestation Project involves planting large areas with the exotic North American tree species Fraxinus pennsylvanica Marsh (ash). As an exotic tree species, ash is very vulnerable to infestations by the emerald...
Adenine base editor containing TadA8e (ABE8e) has been reported in rice. However, the application of ABE8e in other plant species has not been described, and the comparison between ABE8e and ABE7.10, which is widely used in plants, has also been poor...
In this work, a sustainable approach is proposed for upcycling recycled Acrylonitrile–Butadiene–Styrene (ABS) derived from electrical and electronic waste (e-waste) through a combination of electron beam irradiation (EBI) technique and ha...
Hypodontia (dental agenesis) is a genetic disorder, and it has been identified that the mutation C175T in PAX9 could lead to hypodontia. Cas9 nickase (nCas9)-mediated homology-directed repair (HDR) and base editing were used for the correction of thi...
Arterial hypertension (AH) is an important risk factor for cardiovascular diseases, a group of diseases that constitutes the most frequent cause of death worldwide. Most AH patients globally are diagnosed with essential hypertension (EH), since they...
The ability to measure the concentration of specific small molecules continuously and in real-time in complex sample streams would impact many areas of agriculture, food safety, and food production. Monitoring for mycotoxin taint in real time during...
The emerald ash borer (EAB; Agrilus planipennis Fairmaire) is a deadly pest of ash trees (Fraxinus spp.) in North America. Chemical and biological control methods are already in use against EAB, but additional integrated pest management (IPM) strateg...
Despite the success of dichotomous sentiment analysis, it does not encompass the various emotional colors of users in reality, which can be more plentiful than a mere positive or negative association. Moreover, the complexity and imbalanced nature of...
The emerald ash borer (EAB) is an invasive beetle that has killed hundreds of millions of ash trees throughout North America since its arrival. The use of entomopathogenic fungi as part of integrated pest management approaches is considered effective...
RNA interference (RNAi) is a naturally occurring process inhibiting gene expression, and recent advances in our understanding of the mechanism have allowed its development as a tool against insect pests. A major challenge for deployment in the field...
Emerald ash borer (EAB), Agrilus planipennis, native to East Asia, is an invasive pest of ash in North America and European Russia. This quarantine species is a threat to ash trees all over Europe. Survey in ten provinces of European Russia in 2019–2...
Ash species (Fraxinus spp.) in Europe are threatened by the Emerald Ash Borer (Agrilus planipennis, EAB), an invasive wood boring beetle native to East Asia and currently spreading from European Russia westwards. Based on a high-resolution habitat di...
Emerald ash borer (EAB) continues to spread across North America, infesting native ash trees and changing the forested landscape. Black ash wetland forests are severely affected by EAB. As black ash wetland forests provide integral ecosystem services...
The present study investigates the relationship between the near-infrared (NIR) spectral characteristics of cross-linked polyethylene (XLPE) insulation materials and their macroscopic properties, with the aim of establishing a reference framework for...
CRISPR/Cas9-based cytosine base editors (CBEs) and adenine base editors (ABEs) can efficiently mediate C-to-T/G-to-A and A-to-G/T-to-C substitutions, respectively; however, achieving base transversions (C-to-G/C-to-A and A-to-T/A-to-C) is challenging...
The Ab-Bid deposit, located in the Tabas-Posht e Badam metallogenic belt (TPMB) in Central Iran, is the largest Pb-Zn (±Cu) deposit in the Behadad-Kuhbanan mining district. Sulfide mineralization in the Ab-Bid deposit formed in Middle Triassic...
The rapid and extensive expansion of emerald ash borer (EAB) in North America since 2002 may eliminate most existing ash stands, likely affecting critical ecosystem services associated with water and carbon cycling. To our knowledge, no studies have...
Induction of broadly neutralizing antibodies targeting ectodomain of the transmembrane (TM) glycoprotein gp41 HIV-1 provides a basis for the development of a universal anti-viral vaccine. The HeLa cell-derived TZM-bl reporter cell line is widely used...
Alisol B 23-acetate (AB23A), a natural triterpenoid, has been reported to exert hepatoprotective and antitumor activities. Aiming to investigate the anti-inflammatory activity, this study examined the effect of AB23A on mast cells and allergic reacti...
Background/Objectives: The increasing use of pea protein in plant-based foods raises concerns about IgE-mediated reactions, particularly in individuals sensitized to peanut. Knowledge on clinically relevant pea allergens and the impact of heat proces...
Protein serine/threonine phosphatase 2A (PP2A) regulates diverse cellular processes via the formation of ~100 heterotrimeric holoenzymes. However, a scarcity of knowledge on substrate recognition by various PP2A holoenzymes has greatly prevented the...
African swine fever virus (ASFV) is a highly pathogenic DNA virus that continues to circulate globally and poses a serious threat to the swine industry. However, the antigenic complexity of ASFV poses formidable challenges for vaccine and diagnostic...
Electrochemical aptamer-based biosensors (E-ABs) are attractive candidates for use in biomarker detection systems due to their sensitivity, rapid response, and design flexibility. There are only several redox probes that were employed previously for...
Novel AB-Polybenzimidazole (AB-PBI)/TiO2 nanocomposite membranes have been prepared using a synthetic green chemistry approach. Modified Eaton’s reagent (methansulfonic acid/P2O5) was used as both reaction media for microwave-assisted synthesis...
This study investigates the effect of extrusion screw speed and carbon nanotube (CNT) concentration on the thermal, mechanical, and electromagnetic interference shielding effectiveness (EMI SE) properties of Polycarbonate (PC)/acrylonitrile-butadiene...
This paper presents a multi-strategy enhanced bald eagle search algorithm (EAB-BES) for 3D UAV path planning in urban environments. EAB-BES addresses key limitations of the traditional bald eagle search (BES) algorithm, including slow convergence, su...
Immune-mediated hemolytic anemia (IMHA) is a common autoimmune disorder in dogs with a high fatality rate and it remains a therapeutic challenge. The marine lipid extract, EAB-277, is a natural anti-inflammatory nutraceutical product. However, the ef...
The emerald ash borer, EAB (Agrilus planipennis) is a devastating alien pest of ash trees. It is spreading in European Russia and Ukraine and will appear in other European countries. Our aim was to determine the regions of Europe where the winter tem...
Demand for fast and convenient dental whitening has increased in recent years. This paper compares the efficacy of three home whitening systems (TiON Take Home with (W), Opalescence Go (G), and Angelus Home 16% (A)) and presents a clinical case. W an...
The geometrical re parameters of trans-azobenzene (E-AB) free molecule were refined by gas electron diffraction (GED) method using available experimental data obtained previously by S. Konaka and coworkers. Structural analysis was carried out by vari...
In large-scale e-commerce, recommendation systems must overcome the shortcomings of conventional models, which often struggle to convert user interest into purchases. This study proposes a revenue-driven recommendation approach that explicitly incorp...
The technology of additive manufacturing (AM) has transformed the fields of machinery, aerospace, and electronics. Adopting cost-effective, precise, and rapid procedures in AM is one of the major concerns of today’s industry. Stereolithography...
Poly-γ-glutamic acid (γ-PGA) is an attractive biopolymer for medical, agri-food, and environmental applications. Although microbial synthesis by Bacilli fed on waste streams has been widely adopted, the obtainment of efficient sustainable...
Recombinant monoclonal antibody (mAb) botulinum neurotoxin (BoNT) antitoxins, consisting of three mAbs that bind non-overlapping epitopes, are highly potent. However, the three-mAb mixtures pose unique development and manufacturing challenges. Combin...
We report a methylene blue (MB)-modified electrochemical aptamer (E-AB) sensor for determining microcystin-LR (MC-LR). The signal transduction of the sensor was based on changes in conformation and position of MB induced by the binding between MC-LR...
The COVID-19 pandemic, caused by SARS-CoV-2, emerges as a global health problem, as the viral genome is evolving rapidly to form several variants. Advancement and progress in the development of effective vaccines and neutralizing monoclonal antibodie...
Alzheimer’s disease (AD) is a neurological disease, and its signs and symptoms appear slowly over time. Although current Alzheimer’s disease treatments can alleviate symptoms, they cannot prevent the disease from progressing. To accuratel...
In most cases, invasive aspergillosis (IA) is caused by A. fumigatus, though infections with other Aspergillus spp. with lower susceptibilities to amphotericin B (AmB) gain ground. A. terreus, for instance, is the second leading cause of IA in humans...
In the present work, energy levels, oscillator strengths, radiative rates and wavelengths of Be-like iron (Fe\(^{22+}\)) from ab-initio calculations using the multiconfiguration Dirac-Hartree-Fock method are presented. These quantities have been calc...
We have investigated the effect of the Ni substitution on the local structure and the valence electronic states of the
Borate transporters are membrane transport proteins that regulate intracellular borate levels. In plants, borate is a micronutrient essential for growth but is toxic in excess, while in yeast, borate is unnecessary for growth and borate export confer...
2 November 2022
The Islamic month of Ramadan is marked by fasting, when Muslims refrain from eating and drinking from dawn to sunset, which has an impact on their dietary habits. The study aimed to assess Nigerian Muslims’ dietary modifications during Ramadan...
Radiomics is the process of extracting useful quantitative features of high-dimensional data that allows for automated disease classification, including atherosclerotic disease. Hence, this study aimed to quantify and extract the radiomic features fr...
Accurate characterization of surface reflection is essential for retrieval of aerosols using downward-looking remote sensors. In this paper, observations from the Ground-based Multiangle SpectroPolarimetric Imager (GroundMSPI) are used to evaluate a...
Background: The potential positive interaction between intermittent fasting (IF) and brain-derived neurotrophic factor (BDNF) on cognitive function has been widely discussed. This systematic review tried to assess the efficacy of interventions with d...
Diseases of the central nervous system, which once occupied a large component of the pharmaceutical industry research and development portfolio, have for many years played a smaller part in major pharma pipelines—primarily due to the well cited...
The field of bone tissue engineering has shown a great variety of bone graft substitute materials under development to date, with the aim to reconstruct new bone tissue while maintaining characteristics close to the native bone. Currently, insufficie...
Kinase inhibitors are potent therapeutic agents in cancer treatment, but their effectiveness is frequently restricted by the inability to image the tumor microenvironment. To address this constraint, kinase inhibitor–fluorophore conjugates have...
In over eighty years, despite successive antibiotics discoveries, the rapid advent of multidrug resistance among bacterial pathogens has jolted our misapprehension of success over them. Resistance is spreading faster than the discovery of new antibio...
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