Special Issue "Nucleic Acid Aptamers"
Deadline for manuscript submissions: closed (10 March 2018)
Nucleic acid aptamers are DNA or RNA molecules that can specifically bind to their targets to form stable target/aptamer complexes. Since the establishment of the systematic evolution of ligands by exponential enrichment method around 1990, nucleic acid aptamers for various targets have been developed. Numerous improved methodologies for their selections and various applications, such as bioimaging, diagnoses, molecular therapies, logic gates, and DNA origami technology, have been reported to date. To achieve improved binding affinity and specificity, increased in vivo stability, and further expanded applications, computational predictions, engineering, and chemical modifications have also been attempted. Among these, some attempts have been successful in efficient acquisition of high affinity aptamers and practical uses. However, technical issues still remain in aptamer development. The present Special Issue is aimed at covering a new aspect of research and development pertaining to nucleic acid aptamers. For example, papers regarding novel methodologies for selections and structural/functional characterizations, newly acquired aptamers, engineering/modification strategies, in silico studies, and diverse applications, as well as related elemental technologies and materials for the potential uses will be invited.
Prof. Masayasu Kuwahara
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- xenonucleic acids
- polymerase variants
- therapeutic and diagnositic nucleic acids