Selective decalcification of vanadium-bearing steel slag via hydrochloric acid pretreatment was investigated in this work. The influences of hydrochloric acid concentration, temperature, reaction time, and liquid-to-solid ratio on Ca and V leaching f...
This study reports the synthesis of borneol mandelate from L-borneol, (R)-(-)-mandelic acid, and titanium sulfate, along with its characterization and acute toxicity assessment in zebrafish. The product was quantified by GC and structurally confirmed...
Food waste is a heterogeneous, moisture-rich substrate with substantial potential for renewable methane recovery, but variability in composition, hydrolysis and reactor stability constrains reliable anaerobic-digestion performance. This study present...
To develop human carbonic anhydrase (hCA) IX/XII-targeted therapeutics for glioblastoma multiforme (GBM), novel dithiocarbamate (DTC)-based compounds were synthesized and evaluated for their inhibitory activity against hCA I, II, IX, and XII isoforms...
Ag2O-loaded Co3O4 composites (Ag2O/Co3O4) were prepared by the sol–gel auto-combustion method. Their morphology, microstructure, and textural properties were characterized by scanning electron microscopy (SEM) coupled with energy-dispersive X-r...
Quinolines constitute privileged N-heterocyclic scaffolds with widespread applications in medicinal and synthetic chemistry, yet classical Doebner–von Miller (DvM) synthesis generally relies on harsh acidic conditions, volatile organic solvents...
Pyrrolizidine alkaloids (PAs) are a chemically diverse group of plant-derived toxins whose quantification in botanical materials remains analytically challenging. This study integrates previously established nano zirconium silicate (NZS) enrichment w...
Natural bioactive compounds, such as essential oils, have attracted increasing attention for the sustainable management of plant diseases. However, their high volatility, chemical instability, and poor water solubility limit agricultural applications...
Background: Cardiovascular hemodynamic stress may be associated with alterations in the circulating ionome. We investigated whether a hypothesis-driven multielement composite, the congestion-associated ionomic dysregulation score (CIDS; higher copper...
Cannabis sativa L. seeds have been traditionally used in Moroccan folk medicine and are increasingly recognized as a valuable source of nutrients and bioactive phytochemicals with promising therapeutic properties. Despite their widespread traditional...
Oroxylum indicum (L.) Kurz is an edible medicinal plant whose pharmacological properties are largely attributed to four flavonoids: baicalein, oroxin A, oroxin B, and chrysin. This study developed an ultrasound-assisted extraction method using enviro...
Water plays an active role in organic chemistry, yet the number of explicit water molecules required to describe the local solvation environment of small organic substrates remains poorly established. Herein, we examine the solvation of five small po...
This work studies the synthesis of complexes using chlorambucil (La-CLA) as a ligand and lanthanum as a metallic center, in order to enhance their biological activities. The compounds produced were characterized by infrared spectroscopy and 13C and 1...
Melastoma sanguineum Sims is a traditional medicinal plant with edible fruits, but little is known about the biological activities of its essential oil. In this study, Caenorhabditis elegans was used as an animal model to investigate the antioxidant...
In this research paper, chiral separation of three amino acids (AAs), namely, tryptophan (Trp), tyrosine (Tyr), and phenylalanine (Phe), was achieved by capillary electrophoresis with clindamycin phosphate as the chiral selector. Factors affecting th...
This study investigated the phytochemical profile, antioxidant capacity, and immunomodulatory properties of Pinus sylvestris xylem sap harvested from the Kastamonu region of Türkiye during the early spring active sap-flow period. Quantitative sc...
Background/Objectives: Chaulmoogra oil (ChO), from Hydnocarpus wightianus Blume seeds, is returning to use as the lipid phase of transdermal carriers, yet no pharmacopoeial monograph governs it. This work asked whether lipid classes associated with h...
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The simultaneous separation of therapeutic insulin analogues by capillary electrophoresis (CE) remains challenging because of their high structural similarity and their tendency to adsorb onto the capillary surface. This study investigated the applic...
Salidroside is a bioactive compound extracted from the traditional Chinese medicinal plant Rhodiola rosea that exerts differential regulatory effects on cell viability depending on cell type and physiological state. Sertoli cells are important testic...
Helichrysum italicum (Roth) G. Don subsp. italicum is one of the most valuable Mediterranean aromatic species owing to its essential oil, which is widely used in pharmaceutical, cosmetic, and nutraceutical applications. However, comparative phytochem...
Understanding the molecular organization of surfactants at the sc-CO2/water interface is essential for the rational design of CO2-philic interfacial formulations with reduced fluorine content. In this work, three low-fluorinated anionic surfactants (...
Sacha inchi oil is a highly unsaturated edible oil with considerable nutritional value but high susceptibility to oxidative deterioration. This study evaluated the effects of matico (Piper aduncum L.), real lemon (Citrus limon (L.) Burm. f.), and spe...
Pyrazine (1,4-diazine) and its annulated derivatives are promising platforms for colorimetric and fluorescent chemosensors of biologically and environmentally relevant metal cations, including Hg2+, Cu2+, Zn2+, Pb2+, Fe3+, Al3+, Co2+, Ni2+, Ag+ and C...
Tetrandrine (TET) is a bisbenzylisoquinoline alkaloid with promising anticancer activity, although its limited selectivity toward malignant over non-cancerous cells restricts its therapeutic potential. A series of mono- and bis-N-substituted tetrandr...
Chemicals are widely used to protect humans from biological threats. Ticks are among the most dangerous biological species, as they transmit dangerous diseases such as Q-fever, Crimean–Congo hemorrhagic fever, tick-borne encephalitis, and other...
This study aimed to obtain crude, purified, and fractionated anthocyanin-rich extracts of three black bean cultivars from the South Pacific Region of Mexico (Chiapas, Guerrero, and Oaxaca). The extracts were obtained using an Amberlite XAD-7HP column...
The use of herbal medicinal products and dietary supplements has increased significantly in recent years. Insufficient knowledge regarding the effects of herbal raw materials, as well as their potential adverse effects and interactions with medicatio...
In this study, thiazole derivatives 13–23 were synthesized as novel cholinesterase inhibitors. Their structures were elucidated using 1H-NMR, 13C-NMR, and elemental analysis techniques. The binding positions and efficiencies of the designed com...
Polyimide (PI) films serving as high-temperature dielectric and structural materials are increasingly required to combine mechanical robustness, thermal stability, and low dielectric properties for advanced electronic packaging. Herein, PI composite...
The present study describes the development and validation of a simple, rapid, and reliable RP-HPLC method for the simultaneous estimation of acyclovir and doxepin hydrochloride in bulk and topical cream formulation using an Analytical Quality by Des...
The occurrence of antimicrobial resistance (AMR) and chemoresistance (CMR) during bacterial infections and cancer progression, respectively, has become a serious threat leading to increased mortality rates and putting significant pressure on healthca...
Oxidative stress, mitochondrial dysfunction, and chronic neuroinflammation are closely interconnected processes involved in the pathogenesis and progression of neurodegenerative diseases. Bee-derived products, including honey, propolis, royal jelly,...
Ficus species are recognized for their nutritional and phytochemical diversity; however, the infructescences of Ficus benjamina and Ficus mathewsii remain underutilized. This study aimed to evaluate the nutritional composition, volatile and phenolic...
Optimizing the morphology and structure of noble metal nanomaterials is critical for the design of high-performance surface-enhanced Raman scattering (SERS) substrates for trace analyte detection. A plasmon-tunable SERS platform consisting of AuAg al...
The Gibbs equation describes the relationship between the enthalpy (∆H), entropy (∆S), and Gibbs energy (∆G) changes in physicochemical processes: ∆G = ∆H − T∆S. It remains a cornerstone of chemical thermodyn...
Njangsa seed oil (NSO) is rich in polyunsaturated fatty acids and represents an underexplored plant source for producing conjugated linoleic acid (CLA). This study explored the production of CLA from NSO via alkali isomerization, as well as and its s...
Ionic liquids (ILs) are often described as designer solvents. However, a single cation–anion pair rarely optimizes phase stability, transport properties, and task-specific functions simultaneously. Mixing introduces composition as a continuous...
Longitudinal bone growth is primarily regulated by the growth hormone (GH)-insulin-like growth factor-1 (IGF-1) axis. However, non-hormonal and orally administered strategies for promoting longitudinal growth remain limited. Here, we investigated the...
Tm3+, Yb3+: GdxBi2−xWO6 series upconversion luminescent materials were synthesized via a solid-state method. Calculations and XRD analysis reveal that Gd3+ in the lattice exhibits both substitutional and interstitial doping. Compared with the N...
Ziziphus seeds, an abundant and low-cost lignocellulosic residue generated across the value chains of Z. mauritiana, Z. spina-christi, and Z. jujuba in arid and semi-arid regions, have emerged as a promising but under-synthesized feedstock for adsorp...
Cannabigerol (CBG) exerts vasorelaxant effects in human pulmonary arteries and lowers blood pressure (BP) in normotensive mice. However, data on the cardiovascular effects of CBG in hypertension and platelet function remain limited. Consequently, the...
Xenon (Xe) is an inert noble gas receiving increasing attention in medical research due to its anesthetic properties, ability to regulate metabolic processes, and broad organoprotective effects. Due to its small size and non-covalent intermolecular i...
The presence of organic pollutants in soil represents one of the main remediation challenges of the 21st century, and in this regard, peroxymonosulfate- (PMS) and persulfate (PS)-based advanced oxidation processes (AOPs) are among the most promising...
Ruta chalepensis L. var. angustifolia (Pers.) Willk. (Rutaceae) has been traditionally associated with hypocholesterolemic effects, although the bioactive metabolites responsible for this activity remain largely unknown. This study aimed to fractiona...
Background: DNase I inhibitors may be useful as biochemical tools and as potential leads for investigating pathological processes associated with excessive DNA degradation. Squaramides represent attractive scaffolds for drug discovery owing to their...
Layered transition-metal oxides (NaxTMO2) are among the most promising cathode candidates for sodium-ion batteries, yet their interfacial degradation under high voltage, deep desodiation, and humid environments remains the central bottleneck to comme...
Civilizational development, which depends on the availability of raw materials, has accelerated tremendously in recent decades. This is due to globalization and the growth of emerging markets. It represents a huge opportunity for an innovative approa...
Dietary polyphenols, abundant in fruits, vegetables, tea, coffee, cocoa, and wine, have been widely investigated for their potential relevance to cardiovascular health. Their proposed protective effects extend beyond classical antioxidant activity, e...
The rational design and fabrication of semiconductor photocatalysts possessing high intrinsic activity are pivotal for the remediation of tetracycline (TC)-contaminated aqueous streams. Herein, we synthesized a LaVO4/Bi2O2S heterostructure and compre...
