A Convenient Synthesis of Amino Acid Methyl Esters
The Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China
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Molecules 2008, 13(5), 1111-1119; https://doi.org/10.3390/molecules13051111
Received: 29 April 2008 / Revised: 5 May 2008 / Accepted: 6 May 2008 / Published: 8 May 2008
A series of amino acid methyl ester hydrochlorides were prepared in good toexcellent yields by the room temperature reaction of amino acids with methanol in thepresence of trimethylchlorosilane. This method is not only compatible with natural aminoacids, but also with other aromatic and aliphatic amino acids.
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Keywords:
Amino acid methyl ester hydrochlorides; amino acids; trimethylchlorosilane; esterification
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MDPI and ACS Style
Li, J.; Sha, Y. A Convenient Synthesis of Amino Acid Methyl Esters. Molecules 2008, 13, 1111-1119. https://doi.org/10.3390/molecules13051111
AMA Style
Li J, Sha Y. A Convenient Synthesis of Amino Acid Methyl Esters. Molecules. 2008; 13(5):1111-1119. https://doi.org/10.3390/molecules13051111
Chicago/Turabian StyleLi, Jiabo; Sha, Yaowu. 2008. "A Convenient Synthesis of Amino Acid Methyl Esters" Molecules 13, no. 5: 1111-1119. https://doi.org/10.3390/molecules13051111
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