Next Article in Journal
Tetrabutylammonium Bromide Media Aza-Michael Addition of 1,2,3,6-Tetrahydrophthalimide to Symmetrical Fumaric Esters and Acrylic Esters under Solvent-Free Conditions
Next Article in Special Issue
Antioxidant Vitamins and Their Use in Preventing Cardiovascular Disease
Previous Article in Journal / Special Issue
Antioxidant-Prooxidant Properties of a New Organoselenium Compound Library
Open AccessReview

Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties

by Jin Dai 1,2 and Russell J. Mumper 3,*
1
Four Tigers LLC, 1501 Bull Lea Road, Suite 105, Lexington, Kentucky 40511 USA
2
Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, USA
3
Division of Molecular Pharmaceutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
*
Author to whom correspondence should be addressed.
Molecules 2010, 15(10), 7313-7352; https://doi.org/10.3390/molecules15107313
Received: 10 September 2010 / Revised: 15 October 2010 / Accepted: 19 October 2010 / Published: 21 October 2010
(This article belongs to the Special Issue Antioxidants)
Phenolics are broadly distributed in the plant kingdom and are the most abundant secondary metabolites of plants. Plant polyphenols have drawn increasing attention due to their potent antioxidant properties and their marked effects in the prevention of various oxidative stress associated diseases such as cancer. In the last few years, the identification and development of phenolic compounds or extracts from different plants has become a major area of health- and medical-related research. This review provides an updated and comprehensive overview on phenolic extraction, purification, analysis and quantification as well as their antioxidant properties. Furthermore, the anticancer effects of phenolics in-vitro and in-vivo animal models are viewed, including recent human intervention studies. Finally, possible mechanisms of action involving antioxidant and pro-oxidant activity as well as interference with cellular functions are discussed. View Full-Text
Keywords: plant phenolics; extraction; analysis; antioxidant; anticancer plant phenolics; extraction; analysis; antioxidant; anticancer
Show Figures

Figure 1

MDPI and ACS Style

Dai, J.; Mumper, R.J. Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties. Molecules 2010, 15, 7313-7352.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop