Next Article in Journal
Synthesis and Cytotoxic Analysis of Novel Myrtenyl Grafted Pseudo-Peptides Revealed Potential Candidates for Anticancer Therapy
Next Article in Special Issue
Three-Component Access to Functionalized Spiropyrrolidine Heterocyclic Scaffolds and Their Cholinesterase Inhibitory Activity
Previous Article in Journal
Cannabis sativa L. Inflorescences from Monoecious Cultivars Grown in Central Italy: An Untargeted Chemical Characterization from Early Flowering to Ripening
Previous Article in Special Issue
Recent Advances in the Synthesis of Oxazole-Based Molecules via van Leusen Oxazole Synthesis
Open AccessFeature PaperReview

A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications

School of Chemistry & Physics, University of KwaZulu-Natal, Westville Campus, Chiltern Hills, Durban 4000, South Africa
*
Author to whom correspondence should be addressed.
Academic Editors: Anna Carbone and Fabio Bertozzi
Molecules 2020, 25(8), 1909; https://doi.org/10.3390/molecules25081909
Received: 10 March 2020 / Revised: 12 April 2020 / Accepted: 15 April 2020 / Published: 20 April 2020
(This article belongs to the Special Issue Nitrogen Heterocycles in Medicinal Chemistry)
The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. In the forthcoming decade, a much greater share of new nitrogen-based pharmaceuticals is anticipated. Many new nitrogen-based heterocycles have been designed. The number of novel N-heterocyclic moieties with significant physiological properties and promising applications in medicinal chemistry is ever-growing. In this review, we consolidate the recent advances on novel nitrogen-containing heterocycles and their distinct biological activities, reported over the past one year (2019 to early 2020). This review highlights the trends in the use of nitrogen-based moieties in drug design and the development of different potent and competent candidates against various diseases. View Full-Text
Keywords: nitrogen-based heterocycles; current trends; biological activities; structure-activity relationship nitrogen-based heterocycles; current trends; biological activities; structure-activity relationship
Show Figures

Graphical abstract

MDPI and ACS Style

Kerru, N.; Gummidi, L.; Maddila, S.; Gangu, K.K.; Jonnalagadda, S.B. A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications. Molecules 2020, 25, 1909.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop