Potassium is essential for plant growth and development and stress adaptation. The maintenance of potassium homeostasis involves a series of potassium channels and transporters, which promote the movement of potassium ions (K+) across cell membranes...
P-glycoprotein (P-gp) affects the transport of many drugs; including puerarin and vincristine. Our previous study demonstrated that imperatorin increased the intestinal absorption of puerarin and vincristine by inhibiting P-gp-mediated drug efflux. H...
Vitamin A has biological functions as diverse as sensing light for vision, regulating stem cell differentiation, maintaining epithelial integrity, promoting immune competency, regulating learning and memory, and acting as a key developmental morphoge...
This paper investigated the effect and mechanism of theaflavins (TFs) on fluoride (F−) uptake and transport in the Caco-2 cell model through structural chemistry and transcriptome analysis. The results showed that the four major TFs (TF, TF3G, TF3′G...
Glucose transporters GLUT1 belong to the major facilitator superfamily and are essential to human glucose uptake. The overexpression of GLUT1 in tumor cells designates it as a pivotal target for glycoconjugate anticancer drugs. However, the interacti...
Ion and water transport at the Angstrom/Nano scale has always been one of the focuses of experimental and theoretical research. In particular, the surface properties of the angstrom channel and the solid-liquid interface interaction will play a decis...
In this study, the charge transport mechanism of Pd/Si-based FS-GaN Schottky diodes was investigated. A temperature-dependent current–voltage analysis revealed that the I-V characteristics of the diodes show a good rectifying behavior with a la...
Puerarin (PUR) and gastrodin (GAS) are often used in combined way for treating diseases caused by microcirculation disorders. The current study aimed to investigate the absorption and transportation mechanism of PUR and GAS and their interaction via...
Basic knowledge about the factors and mechanisms affecting the performance of solar cells and their identification is essential when thinking of future improvements to the device. Within this paper, we investigated the current transport mechanism in...
Previous studies indicate that mass transport deposits are related to the dynamic accumulation of natural gas hydrates and gas leakage. This research aims to elucidate the causal mechanism of seabed seepage in the western region of the southeastern Q...
INDY (I’m Not Dead Yet) is a plasma membrane transporter for citrate, first identified in Drosophila. Partial deficiency of INDY extends lifespan in this organism in a manner similar to that of caloric restriction. The mammalian counterpart (NaCT/SLC...
(1) Background: Application of nanotechnology or nanomaterials in agricultural food crops has attracted increasing attention with regard to improving crop production, quality, and nutrient utilization. Gold nanoparticles (Au-NPs) have been reported t...
4-Nitroaniline (4NA) is a common organic pollutant that is released into the environment during the manufacture and processing of a wide variety of industrial products. This article describes the use of an emulsion liquid membrane process to remove 4...
Iron is one of the necessary trace elements for plant growth and the human body. The ‘hidden hunger’ phenomenon in the human body caused by an imbalance of iron in soil is increasingly prominent. Addressing this issue and optimizing soil...
Proton transport through perfluorosulfonic acid (PFSA) membranes sets the ohmic resistance of proton exchange membrane fuel cells and is most constrained during cold start, when reduced hydration coincides with sub-ambient temperatures, yet the condi...
This article describes the swelling and release mechanisms of paracetamol in polyurethane nanocomposite hydrogels containing Cloisite® 30B (organically modified montmorillonite). The transport mechanism, swelling and release processes of the acti...
To improve understanding of the characteristics of extreme summer rainfall and its water vapor transport in the eastern part of southwestern China (ESWC), this study analyzed data on daily precipitation from 118 meteorological stations in the ESWC fr...
This study presents a working concept of a model architecture allowing to leverage the state of an entire transport network to make estimated arrival time (ETA) and next-step location predictions. To this end, a combination of an attention mechanism...
Recently, as an emerging material, ultrawide bandgap Ga2O3 has been investigated extensively in solar-blind deep-ultraviolet (DUV) photodetectors (PDs). High sensitivity and signal-to-noise ratio of PDs are essential for the detection of solar-blind...
In this study, a specific Mg–Zn–RE alloy membrane with 6 wt.% zinc and 2.7 wt.% rare earth elements (Y, Gd, La and Ce) was prepared to investigate implant degradation, transport mechanism and guide bone regeneration in vivo. The Mg-membra...
This study investigated the low contact resistivity and Schottky barrier characteristics in p-GaN by modifying the thickness and doping levels of a p-InGaN cap layer. A comparative analysis with highly doped p-InGaN revealed the key mechanisms contri...
N-glycolylneuraminic acid (Neu5Gc) is a specific factor in red meat that induces intestinal disease. Our aim was to investigate the effect of Neu5Gc on the intestinal barrier as well as its mechanism of endocytosis and exocytosis. Ten specific inhibi...
The major facilitator superfamily (MFS) of transporters consists of three classes of membrane transporters: symporters, uniporters, and antiporters. Despite such diverse functions, MFS transporters are believed to undergo similar conformational chang...
Multidrug resistance (MDR) proteins belonging to the ATP-Binding Cassette (ABC) transporter group play a crucial role in the export of cytotoxic drugs across cell membranes. These proteins are particularly fascinating due to their ability to confer d...
Chemical thinning of apple fruitlets is an important practice as it reduces the natural fruit load and, therefore, increases the size of the final fruit for commercial markets. In apples, one chemical thinner used is Metamitron, which is sold as the...
Organogels have recently been considered as materials for transdermal drug delivery media, wherein their transport and mechanical properties are among the most important considerations. Transport through organogels has only recently been investigated...
PFAS-laden fluid-filled porous media may be subjected to various mechanical loads which induce solid deformation and fluid flow and hence PFAS transport. This work employs a poroelasticity theory for unsaturated porous media to address the coupled so...
Multidrug resistance (MDR) can be a serious complication for the treatment of cancer as well as for microbial and parasitic infections. Dysregulated overexpression of several members of the ATP-binding cassette transporter families have been intimate...
P4-ATPase translocates lipids from the exoplasmic to the cytosolic plasma membrane leaflet to maintain lipid asymmetry distribution in eukaryotic cells. P4-ATPase is associated with severe neurodegenerative and metabolic diseases such as neurological...
The financial market has a strong influence on supporting the transition to a zero-emission transport system, as this sector requires large investments to implement low-emission technologies and infrastructure and to promote intermodality. This artic...
Membrane transporters are proteins that mediate the entry and exit of substances through the plasma membrane and organellar membranes and are capable of recognizing and binding to specific substances, thereby facilitating substance transport. Membran...
Arsenic (As) is a metalloid environmental pollutant ubiquitous in nature that causes chronic and irreversible poisoning to humans through its bioaccumulation in the trophic chain. Rice, the staple food crop for 350 million people worldwide, accumulat...
Deep-sea mining, as a critical direction for the future development of mineral resources, places significant importance on the mechanical characteristics of its transportation pipelines for the safety and efficiency of the entire mining system. This...
Large deployment of photovoltaic (PV) installation worldwide demands reliability assurance of the systems to maintain the confidence in the markets. With the diversity of PV applications, it is essential the detection of circumstances that can be the...
Detailed knowledge of the intestinal transport of polymannuronic acid (PM) and polyguluronic acid (PG) is critical for understanding their biological activities. To investigate the transport in the gastrointestinal tract, PM and PG were chemically mo...
With the integration of the global economy and the rapid development of port logistics, the port dangerous goods transportation system faces complex risk-coupling problems, and the probability of accidents keeps climbing. However, the existing resear...
The objective of this study is to construct a refined microscopic transport model that elucidates the transport mechanisms of gas flow within micro-nano pores and fractures. The collective impact of various microscopic transport mechanisms was explai...
25 August 2023
The electrical properties of solution-processed spinel nickel cobaltite (NiCo2O4) nanoparticulated-based metal oxide hole transporting layers are investigated using conductivity and Hall effect measurements. The mechanism of electrical conductivity o...
Inspired by the mechanical principles governing efficient impact load transmission and dissipation in drum shells, this study proposes a novel hierarchical microlattice design strategy that integrates bionic concepts with fractal geometry, aiming to...
Diabetic neuropathy is typically diagnosed with distal sensory and nerve conduction abnormalities. These symptoms may reflect earlier disturbances of axonal maintenance. This review examines axonal transport and cytoskeletal failure as convergent cel...
Federated learning (FL) has emerged as a promising paradigm for privacy-preserving distributed intelligence in modern urban transportation systems, where vehicles collaboratively train global models without sharing raw data. However, the dynamic natu...
The field of medicinal inorganic chemistry has grown consistently during the past 50 years; however, metal-containing coordination compounds represent only a minor proportion of drugs currently on the market, indicating that research in this area has...
Na+/H+ exchangers are essential for Na+ and pH homeostasis in all organisms. Human Na+/H+ exchangers are of high medical interest, and insights into their structure and function are aided by the investigation of prokaryotic homologues. Most prokaryot...
Hongmeiren is a high-quality orange fruit but susceptible to mechanical damage. This work proposes a new packaging format (Packaging C), which used the plastic partition boards to separate the folding plastic basket to avoid the fruits from crushing...
Thermoelectric energy converters based on galvanic cells (TGC) offer the possibility of direct conversion of low-temperature waste heat into electrical energy and could therefore be a promising approach for an increase in the overall efficiency of en...
Polymer inclusion membranes (PIMs) based on PVDF-HFP as the base polymer and Aliquat 336 as the carrier in a mass ratio of 6:4 with concentrations of embedded glass fibers up to 5 wt% were successfully fabricated. Their microstructure, as well as the...
As one of the primary contributors to carbon emissions in China, the transportation sector plays a pivotal role in achieving green and low-carbon development. Considering the spatio-temporal dependency characteristics of transportation carbon emissio...
Efficient proppant transport in conglomerate reservoirs is severely constrained by rough fracture surfaces and strong geometric heterogeneity, leading to premature near-wellbore deposition and insufficient distal support. To address this challenge, t...
Cellular Zn2+ homeostasis is tightly regulated and primarily mediated by designated Zn2+ transport proteins, namely zinc transporters (ZnTs; SLC30) that shuttle Zn2+ efflux, and ZRT-IRT-like proteins (ZIPs; SLC39) that mediate Zn2+ influx. While the...
Based on the 2013 field survey data of hydrology, suspended sediments and bottom sediments in the Central Hangzhou Bay, this paper explores the dynamic mechanism of suspended sediments in Hangzhou Bay by employing material flux decomposition. Meanwhi...
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