Special Issue "Can Membrane Transporters Contribute to Drug Discovery?"
Deadline for manuscript submissions: closed (30 January 2017).
Interests: medicinal chemistry; organic synthesis; heterocycles, P-glycoprotein; anticancer; anticoagulants; chiral drugs; marine natural products
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Membrane transporters are experiencing a renascence. Two families of transporters, the ATP-binding cassette (ABC) and the solute carrier (SLC) transporters, contribute to the efficacy and safety of drugs in the drug development process. The question for this Special Issue of Molecules is “Can membrane transporters contribute to drug discovery?”. We know that many transporters are implicated in human diseases, mainly by affecting endogenous substances and/or drug disposition; such is the case of P-glycoprotein, which has been an “old target” for multidrug resistance and is now being considered for treatment of Alzheimer’s disease.
This Special Issue intends to collect the state-of-the-art in original research and review articles that consider ABC and SLC modulators as potential drug candidates. Select topics are: Membrane transporters in cancer, membrane transporters and antimicrobial resistance, membrane transporters and metabolic disorders, membrane transporters and CNS, membrane transporters and signaling and their role in medicinal chemistry, membrane transporters in detoxifying xenobiotics. You are welcome to generate a unique topic.
Prof. Maria Emília de Sousa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- ATP-binding cassette transporters
- solute carrier transporters
- pharmacological targets
- drug discovery
- drug disposition