Serpentine, a magnesium-bearing gangue mineral commonly associated with pentlandite, severely impairs flotation selectivity through electrostatic heterocoagulation and slime contamination. In this study, a squaramide-based small-molecule depressant (...
Background and Objectives: The goal of this study was to investigate the effect of selective serotonin reuptake inhibitor treatment on the ovarian reserves of women of reproductive age with major depressive disorder. Materials and Methods: The curren...
Objective: The use of selective serotonin reuptake inhibitors (SSRIs) is common among hemodialysis patients who receive treatment for depression. However, studies on the efficacy of SSRIs in patients on chronic hemodialysis are few and have led to co...
Surface-water networks evolve as depressions fill, spill, and connect, whereas conventional digital elevation model (DEM) routing often treats flats and depressions through preprocessing or complete filling. This study introduces selective depression...
Background: Depression is a common psychiatric comorbidity in individuals with Down syndrome (DS), particularly adults, with an estimated lifetime prevalence of at least 10%. The current literature on the treatment of depression in adults with DS is...
This paper studies the effects of sodium polystyrene sulfonate (PSSNa) used as a depressant upon the separation of ilmenite from titanaugite through flotation when sodium oleate (NaOl) is used as a collector by performing single mineral flotation exp...
The current polythetic and operational criteria for major depression inevitably contribute to the heterogeneity of depressive syndromes. The heterogeneity of depressive syndrome has been criticized using the concept of language game in Wittgensteinia...
Biotite in mica-bearing phosphate ores is prone to sliming and forms fine intergrowths with apatite, impairing flotation selectivity. Taurine, sodium lignosulfonate, chitosan, hydroxypropyl distarch phosphate, and carboxymethyl chitosan (CMCS) were s...
Major depressive disorder (MDD) poses a significant challenge in mental healthcare due to difficulties in accurate diagnosis and timely identification. This study explores the potential of machine learning models trained on EEG-based features for dep...
Social media has become an essential platform for understanding human behavior, particularly in relation to mental health conditions such as depression and suicidal tendencies. Given the increasing reliance on digital communication, the ability to au...
Background and objectives: Major depressive disorder (MDD) and cardiovascular diseases (CVDs) represent serious and prevalent medical conditions. Autonomic nervous system (ANS) dysfunctions, expressed by parameters of heart rate variability (HRV) and...
Recent studies on EEG-based automated depression detection have primarily depended on complex deep learning models. While these methods improve classification performance, their practical application is limited by high computational complexity, chall...
Around the world, 5% of adults suffer from depression, which is often inadequately treated. Depression is caused by a complex relationship of cultural, psychological, and physical factors. This growing issue has become a significant public health pro...
To solve the problem of mechanical entrainment and slime coating of fine sericite and chlorite hindering the flotation separation of gold-bearing pyrite in low-grade gold ores, ethylenediamine-N,N’-disuccinic acid (EDDS) was innovatively used a...
Depressive symptoms are increasingly common in middle-aged and older adults and have become a major public health problem. People may experience transitions across different underlying states due to symptom variability over a course of many years. An...
Using hydrogen peroxide (H2O2), a simple and easily accessible reagent, as a selective depressant, flotation separation experiments of chalcopyrite and copper-activated sphalerite were conducted. The micro-flotation tests of single minerals indicated...
The association between selective serotonin reuptake inhibitor (SSRI) treatment and lower bone mineral density (BMD) remains controversial, and further research is required. This study aimed to compare the BMD, levels of bone formation and bone metab...
We recently developed a series of nalfurafine analogs (TK10, TK33, and TK35) that may serve as non-addictive candidate analgesics. These compounds are mixed-action agonists at the kappa and delta opioid receptors (KOR and DOR, respectively) and produ...
There are controversial data on the efficacy and safety profile of selective serotonin reuptake inhibitors (SSRIs) to prevent post-stroke depression (PSD). We performed a systematic search in MEDLINE and SCOPUS databases to identify randomized-contro...
Depression is becoming one of the most prevalent mental disorders. This study looked at five different classification techniques to predict the risk of students’ depression based on their socio-demographics, internet addiction, alcohol use diso...
The Insulin-like growth factor 2 (IGF-2) has been recently proven to alleviate depressive-like behaviors in both rats and mice models. However, its potential role as a peripheral biomarker has not been evaluated in depression. To do this, we measured...
The study of the depression effect of non-toxic depressants on the flotation separation of chalcopyrite from galena is of great importance for both industrial applications and theoretical research. The mixed depressant (DFinal) of four common inhibit...
15 May 2014
A randomized controlled trial was conducted among a potential high-risk group of 1,343 adolescents from low-income areas in The Netherlands to test the effectiveness of the depression prevention program Op Volle Kracht (OVK) as provided by teachers i...
Flotation is a fundamental unit operation in mineral processing; however, achieving high selectivity while reducing the environmental impact of reagents remains a major challenge in phosphate ore beneficiation. Conventional depressants often exhibit...
Background: Mental disorders are disturbances of brain functions that cause cognitive, affective, volitional, and behavioral functions to be disrupted to varying degrees. One of these disorders is depression, a significant factor contributing to the...
(1) Background: Individuals with high levels of state depression are hypothesized to have an impairment of attentional control functions necessary for filtering irrelevant information. This study used the event-related potential of early PD, a marker...
The selective flotation separation of chalcopyrite from pyrite under low-alkalinity conditions remains a challenge due to their similar surface properties. In this study, a sulfonated dextrin (SD) was synthesized via chemical modification and evaluat...
Background/Objectives. Periodontitis is a chronic inflammatory disease influenced by systemic and psychological factors, including depression. Selective serotonin reuptake inhibitors (SSRIs), widely used to treat depression, may also affect periodont...
Efficient separation of Cu–Mo sulfide minerals from moraine materials remains a major challenge for low-grade, high-moraine Cu–Mo ores. Fine-grained muscovite induces severe slime coating and gangue entrainment, thereby markedly reducing...
Both Type 2 Diabetes Mellitus (T2DM) and depression are leading causes of disability despite T2DM being largely preventable and depression being among the most treatable mental health conditions. Diabetes and depression have a bidirectional associati...
Depression is a public health issue that severely affects one’s well being and can cause negative social and economic effects to society. To raise awareness of these problems, this research aims at determining whether the long-lasting effects o...
Background: Antegrade root cardioplegia remains the most popular strategy for myocardial protection during coronary artery bypass graft (CABG) performed with cardiopulmonary bypass (CPB) and aortic cross clamp. In patients with depressed left ventric...
The present methods of diagnosing depression are entirely dependent on self-report ratings or clinical interviews. Those traditional methods are subjective, where the individual may or may not be answering genuinely to questions. In this paper, the d...
Major depressive disorder (MDD) is a life-impairing disorder, and early successful treatment is important for a favorable prognosis. However, early response to antidepressants differs widely among individuals, and is difficult to predict pre-treatmen...
4 July 2018
Misophonia, also known as selective sound sensitivity syndrome, is a condition characterized by strong dislike of specific sounds with accompanying distressing reactions. To date, misophonia is still poorly understood. This study aimed to identify fa...
Statins are widely used as an effective therapy for ischemic vascular disorders and employed for primary and secondary prevention in cardiac and cerebrovascular diseases. Their hemostatic mechanism has also been shown to induce changes in cerebral bl...
The addition of ferrous sulfate as a depressant for Ca-bearing minerals such as calcite and fluorite during scheelite flotation was investigated to recover scheelite from tungsten mine tailings, using Hallimond-tube flotation tests, zeta-potential me...
Major Depressive Disorder (MDD) is a high-risk mental illness that severely affects individuals across all age groups. However, existing research lacks comprehensive analysis and utilization of brain topological features, making it challenging to red...
Antidepressant therapies, such as selective serotonin reuptake inhibitors (SSRIs), are current first-line treatments for Major Depressive Disorder. However, over 50% of treated patients show an inadequate response to initial antidepressant therapy. I...
σ1 receptors play a crucial role in various neurological and neurodegenerative diseases including pain, psychosis, Alzheimer’s disease, and depression. Spirocyclic piperidines represent a promising class of potent σ1 receptor ligand...
The prevalence of neuropsychiatric disorders following traumatic brain injury (TBI) is 20%–50%, and disorders of mood and cognition may remain even after recovery of neurologic function is achieved. Selective serotonin reuptake inhibitors (SSRI) bloc...
Background: Treating depression and anxiety in adolescents can be challenging due to interindividual variability in medication response. With current trial-and-error prescribing practices, adolescents may undergo multiple medication changes over mont...
Background/Objectives: Depressive disorder (DD) is a prevalent psychiatric condition often diagnosed through subjective self-reports, which can be time-consuming and lead to inaccurate assessments. To enhance diagnostic precision, integrating Electro...
11 April 2018
Background: Research addressing the impact of a large number of factors on unemployment is scarce. We aimed to comprehensively identify factors related to unemployment in a sample of persons aged 18–64 from Finland, Poland and Spain. Methods: In this...
Fluorite, CaF2, is considered a strategically important mineral as it is a raw material for many strategic industries. Froth flotation is reported to be the most efficient and economically viable process for the production of an acid-grade product wi...
In the wake of recent advances in machine learning research, the study of pharmacogenomics using predictive algorithms serves as a new paradigmatic application. In this work, our goal was to explore an ensemble machine learning approach which aims to...
Individual treatment outcomes to antidepressants varies widely, yet the determinants to this difference remain elusive. MicroRNA (miRNA) gene expression regulation in major depressive disorder (MDD) has attracted interest as a biomarker. This 4-week...
Beneficial effects of estrogens in the central nervous system (CNS) results from the synergistic combination of their well-orchestrated genomic and non-genomic actions, making them potential broad-spectrum neurotherapeutic agents. However, owing to u...
Background: Animal models are critical tools in the study of psychiatric disorders; however, none of the current models fully reflect human stress-related disorders, even though most of the knowledge about the mechanisms of depression comes from anim...
Pyrite is a major gangue mineral associated with galena and other valuable minerals, and it is necessary to selectively remove pyrite to upgrade the lead concentrate by froth flotation. In this study, the flotation experiments of a single mineral and...
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