New Frontiers in Cerebrovascular Disorders

Dear Colleagues,

Despite the COVID-19 pandemic surge, cerebrovascular disorders continue to represent major causes of disability and mortality worldwide. In recent years, we have witnessed the milestone of mechanical thrombectomy in acute stroke treatment. Further advances in stroke diagnosis and treatment include the application of reperfusion therapies in an extended time window based on advanced neuroimaging, better understanding of the underlying etiologies of cryptogenic stroke, the establishment of transdermal closure in selected patients with PFO-associated stroke, promising minimally invasive techniques for hematoma evacuation, and insights into the mechanisms of stroke-associated neuroinflammation and neurorepair emphasizing on sex and age. It is commonplace to state that for every question answered in clinical medicine and in basic science, multiple new queries and debates arise.

In this Special Issue of JCM, we aim to focus on all promising and developing areas of clinical and basic stroke research, covering fields from experimental ischemia and neuroprotection in the era of endovascular therapies to epidemiology of underrecognized vascular risk factors, brain–heart interaction, and optimization of selection criteria for PFO closure. Research highlighting evolving treatment and prevention paradigms, diagnostic techniques, and pathophysiology of stroke using a multidisciplinary precision-medicine-oriented approach would lie at the core of this Special Issue.

Prof. Dr. Theodoros Karapanayiotides
Prof. Dr. Christos Krogias
Guest Editors

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