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473 Results Found

  • Article
  • Open Access
2 Citations
1,701 Views
17 Pages

Differential Attachment of Engineered Oral Soft Tissues to Implant Surfaces

  • Nour Jalaleddine,
  • Emilia Barker,
  • Kirsty Franklin,
  • Mohamed Jamal and ,
  • Momen A. Atieh,
  • Zaid H. Baqain and
  • Keyvan Moharamzadeh
  • + 2 authors+ 0 author

6 March 2026

Background/Objectives: The formation of a soft tissue seal through mucosal integration around dental implants is critical for potentially achieving long-term peri-implant health and clinical success. Understanding how different implant and abutment s...

(This article belongs to the Special Issue Advances in Periodontal and Peri-Implant Tissues Health Management: 2nd Edition)
  • Review
  • Open Access
88 Citations
16,434 Views
21 Pages

3D Printing Approach in Dentistry: The Future for Personalized Oral Soft Tissue Regeneration

  • Dobrila Nesic,
  • Birgit M. Schaefer,
  • Yue Sun,
  • Nikola Saulacic and
  • Irena Sailer

15 July 2020

Three-dimensional (3D) printing technology allows the production of an individualized 3D object based on a material of choice, a specific computer-aided design and precise manufacturing. Developments in digital technology, smart biomaterials and adva...

(This article belongs to the Special Issue Clinical Advances in Implant Dentistry)
  • Article
  • Open Access
29 Citations
6,751 Views
14 Pages

Implant Soft-Tissue Attachment Using 3D Oral Mucosal Models—A Pilot Study

  • Emilia Barker,
  • Lina AlQobaly,
  • Zahab Shaikh,
  • Kirsty Franklin and
  • Keyvan Moharamzadeh

7 July 2020

Purpose: The aim of this study was to investigate soft-tissue attachment to different metal, ceramic, and polymer implant surfaces using an inflamed, three-dimensional (3D), tissue-engineered, human oral mucosal model, as well as multiple-endpoint qu...

  • Review
  • Open Access
49 Citations
8,122 Views
12 Pages

State of the Art on Biomaterials for Soft Tissue Augmentation in the Oral Cavity. Part I: Natural Polymers-Based Biomaterials

  • Manuel Toledano,
  • Manuel Toledano-Osorio,
  • Álvaro Carrasco-Carmona,
  • Cristina Vallecillo and ,
  • Christopher D. Lynch,
  • María T. Osorio and
  • Raquel Osorio
  • + 2 authors+ 0 author

18 August 2020

Oral soft tissue thickening or grafting procedures are often necessary to cover tooth recession, re-establish an adequate width of keratinized tissue, correct mucogingival deformities improving esthetics, prepare a site for an implant or prosthetics,...

(This article belongs to the Special Issue Polymeric Materials for Dental Applications)
  • Article
  • Open Access
4 Citations
3,728 Views
9 Pages

A Novel Small Form-Factor Handheld Optical Coherence Tomography Probe for Oral Soft Tissue Imaging

  • Alok K. Kushwaha,
  • Minqi Ji,
  • Sneha Sethi,
  • Lisa Jamieson and ,
  • Robert A. McLaughlin and
  • Jiawen Li
  • + 1 author+ 0 author

Tissue imaging is crucial in oral cancer diagnostics. Imaging techniques such as X-ray imaging, magnetic resonance imaging, optical coherence tomography (OCT) and computed tomography (CT) enable the visualization and analysis of tissues, aiding in th...

(This article belongs to the Section B: Biology and Biomedicine)
  • Article
  • Open Access
15 Citations
6,455 Views
11 Pages

Dental MRI of Oral Soft-Tissue Tumors—Optimized Use of Black Bone MRI Sequences and a 15-Channel Mandibular Coil

  • Adib Al-Haj Husain,
  • Esra Sekerci,
  • Daphne Schönegg,
  • Fabienne A. Bosshard and ,
  • Bernd Stadlinger,
  • Sebastian Winklhofer,
  • Marco Piccirelli and
  • Silvio Valdec
  • + 3 authors+ 0 author

Soft-tissue lesions in the oral cavity, one of the most common sites for tumors and tumor-like lesions, can be challenging to diagnose and treat due to the wide spectrum from benign indolent to invasive malignant lesions. We report an abnormally larg...

(This article belongs to the Special Issue New Frontiers of Advanced Imaging in Dentistry)
  • Article
  • Open Access
1,369 Views
14 Pages

Subgingival Plaque Removal Efficacy and Oral Soft Tissue Safety of the Wave Electric Toothbrush: An In Vitro and In Vivo Study

  • Siyuan Huang,
  • Weidong Du,
  • Jie Wu,
  • Yunyang Lu and ,
  • Weili Ku,
  • Xiliu Zhang and
  • Dongsheng Yu
  • + 2 authors+ 0 author

4 January 2026

Background/Objectives: The novel wave electric toothbrush is considered potentially helpful in removing subgingival plaque to prevent the occurrence of periodontal diseases. This study aimed to assess the cleaning efficacy of a novel wave electric to...

  • Review
  • Open Access
23 Citations
6,022 Views
26 Pages

State of the Art on Biomaterials for Soft Tissue Augmentation in the Oral Cavity. Part II: Synthetic Polymers-Based Biomaterials

  • Manuel Toledano,
  • Manuel Toledano-Osorio,
  • Álvaro Carrasco-Carmona,
  • Cristina Vallecillo and ,
  • Raquel Toledano,
  • Antonio Luis Medina-Castillo and
  • Raquel Osorio
  • + 2 authors+ 0 author

17 August 2020

Most of the polymers used as biomaterials for scaffolds are naturally occurring, synthetic biodegradable, and synthetic non-biodegradable polymers. Since synthetic polymers can be adapted for obtaining singular desired characteristics by applying var...

(This article belongs to the Special Issue Polymeric Materials for Dental Applications)
  • Article
  • Open Access
14 Citations
6,037 Views
12 Pages

Real-Time Continuous Monitoring of Oral Soft Tissue Pressure with a Wireless Mouthguard Device for Assessing Tongue Thrusting Habits

  • Hidekazu Matsumoto,
  • Keisuke Tomoto,
  • Gentaro Kawase,
  • Kenta Iitani and ,
  • Koji Toma,
  • Takahiro Arakawa,
  • Kohji Mitsubayashi and
  • Keiji Moriyama
  • + 3 authors+ 0 author

24 May 2023

In orthodontics, understanding the pressure of oral soft tissues on teeth is important to elucidate the cause and establish treatment methods. We developed a small wireless mouthguard (MG)-type device that continuously and unrestrainedly measures pre...

(This article belongs to the Section Wearables)
  • Article
  • Open Access
20 Citations
6,672 Views
21 Pages

Oral Surgical Management of Bone and Soft Tissues in MRONJ Treatment: A Decisional Tree

  • Antonia Marcianò,
  • Erasmo Rubino,
  • Matteo Peditto,
  • Rodolfo Mauceri and
  • Giacomo Oteri

29 June 2020

Background: The aim of the present work was to analyze a 10-year retrospective series of surgically treated medication-related osteonecrosis of the jaws (MRONJ) cases, reporting the clinical outcome and success rate for each adopted procedure in orde...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
2,604 Views
14 Pages

21 May 2024

Intense pulsed light (IPL) is used for aesthetic and therapeutic purposes. According to recent literature, utilizing IPL may boost upregulation of anti-inflammatory cytokines, and downregulation of pro-inflammatory cytokines. Concerns have been raise...

(This article belongs to the Special Issue Photobiomodulation and Its Application in Dentistry)
  • Review
  • Open Access
4 Citations
6,576 Views
16 Pages

CO2 Laser for Esthetic Healing of Injuries and Surgical Wounds with Small Parenchymal Defects in Oral Soft Tissues

  • Yuki Daigo,
  • Erina Daigo,
  • Hiroshi Fukuoka,
  • Nobuko Fukuoka and ,
  • Jun Idogaki,
  • Yusuke Taniguchi,
  • Takashi Tsutsumi,
  • Masatsugu Ishikawa and
  • Kazuya Takahashi
  • + 4 authors+ 0 author

28 November 2023

A number of studies have recently demonstrated the effectiveness of CO2 laser irradiation for the repair and regeneration of scar tissue from injuries or surgical wounds. However, such studies of the oral mucosa are highly limited. Previous studies u...

  • Feature Paper
  • Article
  • Open Access
44 Citations
11,248 Views
11 Pages

A Comparison of Manual Nylon Bristle Toothbrushes versus Thermoplastic Elastomer Toothbrushes in Terms of Cleaning Efficacy and the Biological Potential Role on Gingival Health

  • Andrea Ballini,
  • Michele Di Cosola,
  • Rajiv Saini,
  • Caterina Benincasa and ,
  • Elisabetta Aiello,
  • Benedetta Marrelli,
  • Sugandha Rajiv Saini,
  • Francesco Mattia Ceruso,
  • Riccardo Nocini and
  • Stefania Cantore
  • + 8 authors+ 3 authors

4 August 2021

Background: It is well-known that toothbrushing might be associated with the development of oral soft tissue lesions. There is currently a continuing increase in the demand for new safety and performing materials in daily homecare oral hygiene includ...

(This article belongs to the Special Issue New Trends in Biosciences)
  • Review
  • Open Access
10 Citations
9,397 Views
20 Pages

Bioengineering the Junctional Epithelium in 3D Oral Mucosa Models

  • Marianna Gavriiloglou,
  • Mira Hammad,
  • Jordan M. Iliopoulos,
  • Pierre Layrolle and
  • Danae A. Apatzidou

6 November 2024

Two-dimensional (2D) culture models and animal experiments have been widely used to study the pathogenesis of periodontal and peri-implant diseases and to test new treatment approaches. However, neither of them can reproduce the complexity of human p...

(This article belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)
  • Proceeding Paper
  • Open Access
1 Citations
1,888 Views
4 Pages

26 October 2023

Socket preservation is a procedure in oral surgery that is vital to maintain the integrity of the alveolar ridge following tooth extraction, providing a favorable environment for subsequent implant placement. The success of post-extractive implantolo...

(This article belongs to the Proceedings of The 4th International Electronic Conference on Applied Sciences)
  • Article
  • Open Access
20 Citations
5,823 Views
10 Pages

Various light sources have been applied to enhance the bleaching effect. This study was to identify the histological evaluation in oral soft tissues, as well as tooth color change after tooth bleaching by nonthermal atmospheric pressure plasma (NAPP)...

(This article belongs to the Special Issue In Multidisciplinary Perspectives: Healthcare Technology Research and Education Based on Artificial Intelligence and Simulation)
  • Article
  • Open Access
2 Citations
2,935 Views
18 Pages

Tobacco Residues Deposition at the Surface of Cobalt–Chromium Dental Alloys and the Effect of Cigarette Smoke Extract on Human Mesenchymal Stem Cells: An In Vitro Study

  • Willi-Andrei Uriciuc,
  • Bianca Adina Bosca,
  • Mihaela Tertis,
  • Adrian-Bogdan Țigu and ,
  • Radu-Cristian Moldovan,
  • Maria Suciu,
  • Lucian Barbu-Tudoran,
  • Tamara Liana Topală,
  • Liana Crisan and
  • Aranka Ilea
  • + 6 authors+ 1 author

26 February 2025

The current study began with the following question: Is smoking a balanced factor between human body systems? One of the particular features of the oral cavity is its localization at the gateway of respiratory and digestive. Morphologically, the oral...

(This article belongs to the Section Surface Coatings for Biomedicine and Bioengineering)
  • Article
  • Open Access
3 Citations
2,526 Views
12 Pages

5 January 2023

CO2 lasers have been generally used in oral soft-tissue surgery. Although an increase in power enhances the depth of ablation, the specific correlation between units of power and ablative depth has not been stated. This study aimed to explore ablativ...

(This article belongs to the Special Issue Clinical Applications & Fundamental Researches in Dentistry)
  • Article
  • Open Access
13 Citations
5,481 Views
17 Pages

In fully edentulous patients, the support of a lower dental prosthesis by two implants could improve the chewing ability, retention, and stability of the prosthesis. Despite high success rates of dental implants, complications, such as peri-implantit...

(This article belongs to the Special Issue Osseointegrated Oral implants: Mechanisms of Implant Anchorage, Threats and Long-Term Survival Rates)
  • Article
  • Open Access
11 Citations
3,251 Views
12 Pages

16 October 2020

Despite high success rates of dental implants, surface exposure may occur as a consequence of biologic width establishment associated with surgery. This prospective split-mouth study evaluated the effect of early implant surface exposure caused by in...

(This article belongs to the Special Issue Clinical Advances in Implant Dentistry)
  • Article
  • Open Access
3 Citations
1,998 Views
14 Pages

9 August 2023

Introduction: The objective of this study was to examine the effect of photofunctionalization on the soft-tissue contour formed at the interface of various abutment materials using end-point analyses obtained from the three-dimensional oral mucosal m...

(This article belongs to the Special Issue Dental Implants and Materials (Second Volume))
  • Case Report
  • Open Access
2 Citations
3,846 Views
10 Pages

17 December 2023

Titanium and metal alloys are widely used in implants, crowns, and bridges in implant dentistry owing to their biocompatibility. In this case report of a 45-year-old female patient, multiple implants were placed in five different sextants at differen...

(This article belongs to the Special Issue Recent Advances in Periodontics and Dental Implantology: Part II)
  • Article
  • Open Access
1 Citations
1,735 Views
14 Pages

Impact of Zirconia and Titanium Implant Surfaces of Different Roughness on Oral Epithelial Cells

  • Marco Aoqi Rausch,
  • Zhiwei Tian,
  • Vera Maierhofer,
  • Christian Behm and ,
  • Christian Ulm,
  • Erwin Jonke,
  • Raphael S. Wagner,
  • Benjamin E. Pippenger,
  • Bin Shi and
  • Oleh Andrukhov
  • + 6 authors+ 1 author

4 January 2026

Background/Objectives: Formation of tight contacts between oral soft tissue and dental implants is a significant challenge in contemporary implantology. An essential role in this process is played by oral epithelial cells. In the present study, we in...

(This article belongs to the Special Issue New Perspectives in Periodontology and Implant Dentistry)
  • Article
  • Open Access
7 Citations
4,994 Views
16 Pages

Morpho-Functional Effect of a New Collagen-Based Medical Device on Human Gingival Fibroblasts: An In Vitro Study

  • Tea Romasco,
  • Pier Michele Mandrillo,
  • Erica Morsut,
  • Margherita Tumedei and ,
  • Domitilla Mandatori,
  • Morena Petrini,
  • Maria Cristina Curia,
  • Francesco De Angelis,
  • Camillo D’Arcangelo and
  • Natalia Di Pietro
  • + 6 authors+ 1 author

Maintaining periodontal and peri-implant soft tissues health is crucial for the long-term health of teeth and dental implants. New biomedical strategies aimed at avoiding connective tissue alterations and related diseases (e.g., periodontitis and per...

(This article belongs to the Section Biomedical Engineering and Materials)
  • Article
  • Open Access
7 Citations
4,553 Views
13 Pages

Alteration of Oral and Perioral Soft Tissue in Mice following Incisor Tooth Extraction

  • Takahiro Takagi,
  • Masahito Yamamoto,
  • Aki Sugano,
  • Chiemi Kanehira and ,
  • Kei Kitamura,
  • Masateru Katayama,
  • Katsuhiko Sakai,
  • Masaki Sato and
  • Shinichi Abe
  • + 4 authors+ 0 author

Oral and perioral soft tissues cooperate with other oral and pharyngeal organs to facilitate mastication and swallowing. It is essential for these tissues to maintain their morphology for efficient function. Recently, it was reported that the morphol...

(This article belongs to the Collection Feature Papers in Molecular Pathology, Diagnostics, and Therapeutics)
  • Article
  • Open Access
3 Citations
2,510 Views
14 Pages

22 October 2024

This study evaluates the preferences of dentists regarding the interdisciplinary treatment of patients with gingival recession (GR) and a thin periodontal phenotype, based on their specialization. A cross-sectional study was conducted among Polish de...

(This article belongs to the Section Applied Dentistry and Oral Sciences)
  • Communication
  • Open Access
3 Citations
4,259 Views
6 Pages

Incidence of Chronic Pain following Oral Soft Tissue Biopsies: A Retrospective Study

  • Adir Cohen,
  • Rame Daod,
  • Rakefet Czerninski,
  • Naama Keshet and ,
  • Robert Yanko,
  • Andra Rettman,
  • Yair Sharav,
  • Doron J. Aframian and
  • Yaron Haviv
  • + 4 authors+ 0 author

31 May 2023

Soft tissue oral biopsies (STOB) are commonly performed in the medical field to obtain tissue samples for diagnostic purposes. However, like all invasive procedures, these biopsies may carry risks, such as the development of chronic long-lasting neur...

(This article belongs to the Special Issue Orofacial Pain: Diagnosis and Treatment)
  • Article
  • Open Access
1,318 Views
13 Pages

Exploring the Non-Toxic Therapeutic Potential of Dioscorea communis in Combating Oral Pathogenic Bacteria and Their Effects on Hard and Soft Oral Tissues

  • Anastasia-Ioanna Papantonaki,
  • Eleni Georgakopoulou,
  • Christina Barda,
  • Panagiota Loumou and ,
  • Ioannis Sfiniadakis,
  • Jane Anastassopoulou,
  • Andreas Vitsos and
  • Michail Christou Rallis
  • + 3 authors+ 0 author

Background/Objectives: Gingivitis and dental caries are oral diseases resulting from bacterial accumulation in dental plaque, leading to inflammation, tissue destruction and the demineralization of tooth structures. Dioscorea communis, due to its ant...

(This article belongs to the Special Issue Advancements in Understanding and Treating Oral Pathologies: From Dry Mouth to Oral Cancer)
  • Review
  • Open Access
1,708 Views
12 Pages

Clinical Applications and Therapeutic Potential of Nano-Bio Fusion Gel in Oral Soft Tissue Therapy: A Critical Narrative Review

  • Gábor Kammerhofer,
  • Ákos Tamás Nagy,
  • Árpád Joób-Fancsaly,
  • György Szmirnov and ,
  • Ilona Szmirnova,
  • Dániel Végh,
  • Márton Kivovics,
  • György Szabó and
  • Zsolt Németh
  • + 4 authors+ 0 author

14 May 2026

Oral mucosal and periodontal diseases are commonly associated with persistent inflammation, oxidative stress, impaired wound healing, and reduced oral health-related quality of life. Nano-Bio Fusion (NBF) gingival gel is a bioadhesive nano-formulated...

(This article belongs to the Special Issue Nanogels and Microgels: Fundamental Studies, Applications, and Emerging Trends)
  • Review
  • Open Access
18 Views
61 Pages

4 November 2026

Soft tissue deficiencies around teeth and dental implants remain a common clinical challenge affecting aesthetics, tissue stability, and long-term maintenance. Polymer-based substitutes reduce donor-site morbidity compared with autogenous connective...

(This article belongs to the Special Issue Novel Polymer-Based Biomaterials in Contemporary Dentistry)
  • Article
  • Open Access
1,384 Views
15 Pages

Analysis of Soft Tissue N-Glycome Profiles in Oral Squamous Cell Carcinoma, a Pilot Study

  • Eniko Gebri,
  • Kinga Hogyor,
  • Adrienne Szabo and
  • Andras Guttman

Oral squamous cell carcinoma (OSCC) is an aggressive disease with a glycoproteomically unmapped progression and a low five-year survival rate. Thus, the aim of this pilot study was to explore the N-glycosylation pattern differences in malignant, adja...

(This article belongs to the Special Issue Oral Potentially Malignant Disorders and Oral Cancers: From Molecular Pathology to Therapeutic Approaches)
  • Article
  • Open Access
3 Citations
2,739 Views
11 Pages

Histological Evaluation of Oral Soft Tissue Biopsy by Dual-Wavelength Diode Laser: An Ex Vivo Study

  • Daniele Pergolini,
  • Alessandro Del Vecchio,
  • Mohamed Mohsen,
  • Veronica Cerullo and ,
  • Cinzia Angileri,
  • Eduardo Troiani,
  • Paolo Visca,
  • Barbara Antoniani,
  • Umberto Romeo and
  • Gaspare Palaia
  • + 5 authors+ 0 author

13 June 2025

Background: Diode lasers are valuable in oral surgery due to their excellent hemostasis, minimum post-operative pain, and minimally invasive procedures. A dual-wavelength diode laser in dentistry combines two distinct wavelengths, typically 450 nm an...

(This article belongs to the Section Lasers in Dentistry)
  • Article
  • Open Access
916 Views
18 Pages

Comparative Histological Evaluation of Collagen Matrix Architectures for Soft Tissue Augmentation in the Oral Cavity: A Preclinical Canine Model

  • Hana Shah,
  • Nicholas J. Iglesias,
  • Sara E. Munkwitz,
  • Blaire V. Slavin and ,
  • Zachary M. Stauber,
  • Quinn T. Ehlen,
  • Vasudev Vivekanand Nayak,
  • Seth R. Thaller,
  • Lukasz Witek and
  • Paulo G. Coelho
  • + 5 authors+ 0 author

Intraoral soft-tissue defects are traditionally managed with autogenous connective tissue grafts, though donor site morbidity has driven interest in xenogeneic collagen matrices as alternatives. However, the impact of matrix architecture on soft-tiss...

(This article belongs to the Special Issue Bioengineering Innovations in Plastic and Reconstructive Surgery)
  • Review
  • Open Access
6 Citations
3,075 Views
17 Pages

Background and Objectives: Two of the most exciting new technologies are biotechnology and nanotechnology. The science of nanostructures, or nanotechnology, is concerned with the development, testing, and use of structures and molecules with nanoscal...

(This article belongs to the Special Issue Biomaterials in Bone Regeneration: Challenges to Guarantee Appropriate Biological Features: 2nd Edition)
  • Article
  • Open Access
7 Citations
3,069 Views
21 Pages

Electrophoretically Co-Deposited Collagen–Lactoferrin Membranes with Enhanced Pro-Regenerative Properties for Oral Soft Tissue Regeneration

  • Artem Antoshin,
  • Mikhail Gostev,
  • Yana Khristidis,
  • Aliia Giliazova and ,
  • Sergei Voloshin,
  • Nataliia Blagushina,
  • Olga Smirnova,
  • Ekaterina Diachkova,
  • Elena Istranova and
  • Peter Timashev
  • + 13 authors+ 8 authors

10 December 2023

The quality of soft tissue defect regeneration after dental surgeries largely determines their final success. Collagen membranes have been proposed for the healing of such defects, but in some cases, they do not guarantee a sufficient volume of the r...

(This article belongs to the Special Issue Medical Polymers for Tissue Repair and Regeneration)
  • Article
  • Open Access
20 Citations
4,264 Views
11 Pages

Histological Effects of an Innovative 445 Nm Blue Laser During Oral Soft Tissue Biopsy

  • Gaspare Palaia,
  • Daniele Pergolini,
  • Leonardo D’Alessandro,
  • Raffaella Carletti and ,
  • Alessandro Del Vecchio,
  • Gianluca Tenore,
  • Cira Rosaria Tiziana Di Gioia and
  • Umberto Romeo
  • + 3 authors+ 0 author

Continuously evolving laser devices can be used in various fields; they are an alternative to the traditional cold blade surgery to perform biopsies of oral soft tissues. The aspect focused on in this paper is the possibility to use the 445 nm diode...

(This article belongs to the Special Issue Oral Prevention and Management of Oral Healthcare)
  • Article
  • Open Access
5 Citations
1,992 Views
17 Pages

Systemic Ozone Therapy Improves Oral Hard and Soft Tissue Healing in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Study in Senescent Female Rats

  • Leonardo Alan Delanora,
  • Tiburtino José de Lima Neto,
  • Tiago Esgalha da Rocha,
  • Glauco Rodrigues Carmo Silveira and ,
  • Liran Levin,
  • Jamil Awad Shibli,
  • Edilson Ervolino,
  • Carlos Fernando Mourão and
  • Leonardo P. Faverani
  • + 4 authors+ 0 author

Background/Objectives: Medication-related osteonecrosis of the jaw (MRONJ) is a challenging condition often associated with bisphosphonate use, leading to impaired bone healing and difficult clinical management. Given the lack of predictable therapeu...

(This article belongs to the Collection Feature Papers in Biomedical Materials)
  • Article
  • Open Access
3 Citations
3,962 Views
17 Pages

Background: DNA-RNA compounds have shown promising protection against cell oxidative stress. This study aimed to assess the cytotoxicity, protective, or preventive effect of different experimental formulations on oral epithelia’s oxidative stress in...

(This article belongs to the Special Issue Last Advances in Cosmetics and Personal Care Products Analysis)
  • Review
  • Open Access
33 Citations
6,577 Views
24 Pages

The Impact of Laser Thermal Effect on Histological Evaluation of Oral Soft Tissue Biopsy: Systematic Review

  • Gianluca Tenore,
  • Ahmed Mohsen,
  • Alessandro Nuvoli,
  • Gaspare Palaia and ,
  • Federica Rocchetti,
  • Cira Rosaria Tiziana Di Gioia,
  • Andrea Cicconetti,
  • Umberto Romeo and
  • Alessandro Del Vecchio
  • + 4 authors+ 0 author

18 January 2023

The aim of the study is to review the literature to observe studies that evaluate the extent of the thermal effect of different laser wavelengths on the histological evaluation of oral soft tissue biopsies. An electronic search for published studies...

(This article belongs to the Section Lasers in Dentistry)
  • Review
  • Open Access
56 Citations
12,339 Views
19 Pages

3D Bioprinting for Vascularization

  • Amatullah Mir,
  • Eugenia Lee,
  • Wesley Shih,
  • Sarah Koljaka and ,
  • Anya Wang,
  • Caitlin Jorgensen,
  • Riley Hurr,
  • Amartya Dave,
  • Krupa Sudheendra and
  • Narutoshi Hibino
  • + 5 authors+ 0 author

In the world of clinic treatments, 3D-printed tissue constructs have emerged as a less invasive treatment method for various ailments. Printing processes, scaffold and scaffold free materials, cells used, and imaging for analysis are all factors that...

(This article belongs to the Section Regenerative Engineering)
  • Article
  • Open Access
13 Citations
5,955 Views
14 Pages

10 October 2018

Many oral diseases, such as oral leukoplakia and erythroplakia, which have a high potential for malignant transformations, cause abnormal structural changes in the oral mucosa. These changes are clinically assessed by visual inspection and palpation...

(This article belongs to the Special Issue Electromagnetic Medical Sensing)
  • Article
  • Open Access
1 Citations
917 Views
19 Pages

Lean Management in Medium-Sized Oral Cavity Defect Reconstruction: Facial Artery Musculomucosal Flaps Versus Free Flaps

  • Michał Gontarz,
  • Emilia Lis,
  • Konrad Biel,
  • Jakub Bargiel and ,
  • Krzysztof Gąsiorowski,
  • Kamil Nelke,
  • Dayel Gerardo Rosales Díaz Mirón and
  • Grażyna Wyszyńska-Pawelec
  • + 3 authors+ 0 author

11 December 2025

Background/Objectives: Oral cavity defects highlight the necessity for individualized reconstructive strategies given their anatomical and functional complexity. Reconstructive surgery should optimize healing and function, minimize complications, and...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
25 Citations
7,411 Views
15 Pages

Comparing Direct Measurements and Three-Dimensional (3D) Scans for Evaluating Facial Soft Tissue

  • Boris Gašparović,
  • Luka Morelato,
  • Kristijan Lenac,
  • Goran Mauša and ,
  • Alexei Zhurov and
  • Višnja Katić
  • + 1 author+ 0 author

22 February 2023

The inspection of patients’ soft tissues and the effects of various dental procedures on their facial physiognomy are quite challenging. To minimise discomfort and simplify the process of manual measuring, we performed facial scanning and compu...

(This article belongs to the Special Issue Advances in 3D Imaging and Multimodal Sensing Applications)
  • Article
  • Open Access
23 Citations
3,736 Views
12 Pages

14 January 2021

One of the current major challenges in implant therapy is to minimize marginal bone loss around implants, since it can trigger bacterial colonization of the implant’s neck, leading to its failure. The present study aimed (1) to scientifically v...

(This article belongs to the Special Issue Dental Materials Applied in Oral Health and Systemic Diseases)
  • Article
  • Open Access
8 Citations
859 Views
4 Pages

Dendritic Myxofibrolipoma: Often Misdiagnosed as Sarcoma

  • Awatif Y. Al-Maskery,
  • Salem M. Al-Sidairy and
  • Aisha S. Al-Hamadani

The author describes a benign soft tissue tumor that could be easily mistaken for sarcoma. It represents a combined feature of solitary fibrous tumor and spindle cell lipoma. The clinical presentation, diagnosis, and management of this lesion are dis...

  • Systematic Review
  • Open Access
6 Citations
2,632 Views
17 Pages

Laser-Based Photobiomodulation in Postoperative Tissue Healing in Oral and Maxillofacial Surgery: Systematic Review of RCTs

  • Iwona Niedzielska,
  • Grzegorz Dawiec,
  • Rafał Wiench,
  • Małgorzata Pihut and ,
  • Dariusz Skaba and
  • Josep Arnabat-Dominguez
  • + 1 author+ 0 author

12 January 2026

Background: Postoperative bone healing can be impaired by systemic factors and surgical trauma, leading to delayed recovery. Photobiomodulation therapy (PBMT) has been proposed as a non-invasive method to enhance osteogenesis, but variability in prot...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Review
  • Open Access
3 Citations
7,787 Views
15 Pages

Impact of Tongue Piercings on Oral Health: A Narrative Literature Review

  • Silvia Rojas-Rueda,
  • Nechama S. Citrin,
  • Mark Adam Antal,
  • Rene Garcia-Contreras and ,
  • Carlos A. Jurado and
  • Francisco X. Azpiazu-Flores
  • + 1 author+ 0 author

18 September 2025

Background: Tongue piercing has gained popularity among teenagers and young adults as a form of self-expression, cultural identity, and fashion. However, patients are often unaware of the harmful effects tongue piercings can have on their oral health...

(This article belongs to the Special Issue New Trends, Materials, and Technologies and Consolidating Best Practices in Dentistry, 2nd Edition)
  • Review
  • Open Access
43 Citations
8,855 Views
20 Pages

Mesenchymal Stem Cells in Soft Tissue Regenerative Medicine: A Comprehensive Review

  • Ayesha Rehman,
  • Aditya Nigam,
  • Luigi Laino,
  • Diana Russo and ,
  • Celestino Todisco,
  • Giuseppe Esposito,
  • Fabiano Svolacchia,
  • Federica Giuzio,
  • Vincenzo Desiderio and
  • Giuseppe Ferraro
  • + 5 authors+ 0 author

10 August 2023

Soft tissue regeneration holds significant promise for addressing various clinical challenges, ranging from craniofacial and oral tissue defects to blood vessels, muscle, and fibrous tissue regeneration. Mesenchymal stem cells (MSCs) have emerged as...

  • Hypothesis
  • Open Access
3 Citations
3,826 Views
11 Pages

12 July 2024

In our previous article, we observed and measured a spontaneous growth in the coronal direction of the keratinized tissues present around implants. This growth involved both free margins and interdental papillae, and we indicated our hypothesis on th...

(This article belongs to the Special Issue Advances in Periodontal and Peri-Implant Tissues Health Management)
  • Article
  • Open Access
48 Citations
5,317 Views
12 Pages

Oral Factors That Impact the Oral Microbiota in Parkinson’s Disease

  • Natalia S. Rozas,
  • Gena D. Tribble and
  • Cameron B. Jeter

Patients with Parkinson’s disease (PD) are at increased risk of aspiration pneumonia, their primary cause of death. Their oral microbiota differs from healthy controls, exacerbating this risk. Our goal was to explore if poor oral health, poor oral hy...

(This article belongs to the Special Issue The Oral Microbiome in Systemic Health and Disease: Therapeutics for Reversing Microbial Dysbiosis and Applications in Precision Medicine)

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