Oral Potentially Malignant Disorders and Oral Cancers: From Molecular Pathology to Therapeutic Approaches
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (30 November 2025) | Viewed by 683
Special Issue Editors
2. Department of Oral and Maxillofacial Surgery, Carol Davila Central Military Emergency Hospital, 010825 Bucharest, Romania
Interests: head and neck cancer; prognostic biomarkers; carcinogenesis; imaging; inflammation; salivary
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oral cancer remains a significant global health challenge, with a major negative impact, particularly in regions with limited access to early detection and care. Despite advancements in diagnosis and treatment, survival rates show modest improvements, underscoring the urgent need for a deeper molecular understanding and innovative therapeutic strategies. A critical step toward improving patient outcomes lies in the precise identification and understanding of premalignant lesions, their progression to malignancy, and the molecular mechanisms driving this transformation.
This Special Issue of the International Journal of Molecular Sciences aims to bring together cutting-edge research focused on the molecular pathology of oral potentially malignant disorders (OPMDs) and oral cancer, along with translational approaches that can promote innovation in therapy. Our goal is to provide a platform for researchers, clinicians, and translational scientists to share insights that bridge the gap between molecular science and clinical application, ultimately fostering the development of more effective, personalized approaches to oral cancer prevention and treatment.
We warmly invite clinicians, researchers, and interdisciplinary teams to contribute to this Special Issue and help shape the future of oral cancer management. Original research articles, comprehensive reviews, and short communications that explore molecular biomarkers, signaling pathways, proteomic and genomic alterations, tumor microenvironments, immune responses, microbiota, and the development of novel diagnostic or therapeutic strategies are all welcomed for evaluation in our Special Issue. By bridging fundamental science and translational innovation, this collection seeks to advance precision medicine approaches and improve outcomes for patients with oral cancer.
Prof. Dr. Ana Caruntu
Dr. Nicholas Kalavrezos
Guest Editors
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Keywords
- oral cancer
- oral potentially malignant disorders
- molecular mechanisms in oral cancer
- detection of oral cancer
- pathogenic mechanisms of oral cancer
- immune system
- translational oral cancer
- microbiota oral cancer
- therapy for oral cancer
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