Advances in Periodontal and Peri-Implant Tissues Health Management: 2nd Edition

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Oral Hygiene, Periodontology and Peri-implant Diseases".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 594

Special Issue Editors


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Guest Editor
Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84126 Salerno, Italy
Interests: oral medicine and interconnected systemic disorders; oral microbiome, dysbiosis and interconnected systemic disorders; periodontology and implantology; applied technologies (disease prevention, teledentistry)
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Special Issue Information

Dear Colleagues,

It is a pleasure to invite you to submit manuscripts to the forthcoming Special Issue “Advances in Periodontal and Peri-Implant Tissues Health Management: 2nd Edition” that will be published in Dentistry Journal.

Periodontal and peri-implant diseases constitute an important public health problem, most often under-acknowledged and implicated with general health, oral health-related quality of life and socioeconomic burden, thus enhancing the prevention of periodontitis and peri-implantitis onset and progression should be considered crucial. Moreover, due to the interconnections between periodontal, peri-implant and general health status, principally relying on inflammatory response, periodontal immune-microbiome balance and neurobiological and genetic factors, subjects considered high risk for periodontitis and peri-implantitis development, as well as periodontal patients more prone to the onset or worsening of systemic disorders, should be regarded with caution in multi-disciplinary settings, improving interprofessional communication and collaboration.

Original studies, from basic to clinical research, as well as reviews, case series, case reports and short communications, that provide deeper insights into the etiopathogenesis, the putative interconnections with systemic diseases and neoplasms of such complex disorders and the possible mechanisms underlying aggressive, recurrent and refractory cases, potentially paving the way for innovative primary prevention strategies and therapeutic approaches in regards to more comprehensive and integrated management of periodontal and peri-implant diseases, with high-quality precision on a large scale and with personalized periodontal care for high-risk subjects, will be welcome.

Dr. Federica Di Spirito
Dr. Maria Pia Di Palo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • periodontal health
  • periodontal tissues
  • periodontal disease
  • gingivitis
  • periodontitis
  • peri-implant health
  • peri-implant tissues
  • peri-implant disease
  • peri-implantitis
  • peri-implant mucositis
  • periodontal treatment
  • periodontal care
  • periodontitis management
  • periodontitis management
  • periodontitis prevention
  • peri-implantitis prevention
  • microbiome
  • periodontal manifestations of systemic disease
  • tissue regeneration
  • bone regeneration
  • interdisciplinary approach

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Related Special Issue

Published Papers (2 papers)

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Review

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14 pages, 520 KiB  
Review
Activation of the Nrf2 Signaling Pathway as a Therapeutic Strategy Against Periodontal Disease: A Narrative Review
by Sarmistha Saha, Nadezhda Sachivkina, Ekaterina Lenchenko, Olga Pilshchikova and Alexandr Muraev
Dent. J. 2025, 13(7), 314; https://doi.org/10.3390/dj13070314 - 11 Jul 2025
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Abstract
Periodontitis (PD), is a chronic inflammatory disease of the periodontal system, which includes gingiva, periodontal ligament, alveolar bone, and tooth cement. It is becoming increasingly prevalent globally, and its implications for oral health are profound. The Nrf2 signaling pathway is crucial in managing [...] Read more.
Periodontitis (PD), is a chronic inflammatory disease of the periodontal system, which includes gingiva, periodontal ligament, alveolar bone, and tooth cement. It is becoming increasingly prevalent globally, and its implications for oral health are profound. The Nrf2 signaling pathway is crucial in managing the relationship between inflammation and oxidative stress, making it vital for understanding this disease. Nrf2 interacts with key redox-sensitive inflammatory pathways, playing a vital role in the development of periodontitis. Acknowledging these dynamics underscores the importance of proactively addressing the complex aspects of periodontal disease. This review emphasizes its intricate interactions with redox-sensitive transcription factors vital for sustaining the self-perpetuating inflammatory processes underlying the disease. Additionally, it explores promising therapeutic strategies aimed at Nrf2 activation and encourages more effective management of PD. Full article
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15 pages, 3700 KiB  
Case Report
Electrolytic Cleaning as Part of Surgical Reconstructive Peri-Implantitis Treatment: A Case Series
by Jarno Hakkers, Henny J. A. Meijer, Yvonne C. M. de Waal and Gerry M. Raghoebar
Dent. J. 2025, 13(6), 237; https://doi.org/10.3390/dj13060237 - 26 May 2025
Viewed by 350
Abstract
Background/Objectives: The aim of this study was to assess the workflow and evaluate the clinical, radiographic and patient-reported outcome measures of surgical reconstructive peri-implantitis treatment aided with an electrolytic cleaning device. Methods: This case series describes three patients that presented with peri-implantitis surrounding [...] Read more.
Background/Objectives: The aim of this study was to assess the workflow and evaluate the clinical, radiographic and patient-reported outcome measures of surgical reconstructive peri-implantitis treatment aided with an electrolytic cleaning device. Methods: This case series describes three patients that presented with peri-implantitis surrounding an implant in the anterior maxilla, eligible for surgical reconstructive peri-implantitis treatment. The implant crown was removed, and the patients were surgically treated during which an electrolytic cleaning device was used to clean the implant surface. Thereafter, the implant site was augmented using locally harvested bone and a bovine bone substitute. After 6 months of submerged healing, the implant crown was replaced. Follow-up visits were performed 3 and 6 months after restoration placement. Clinical and radiographical parameters, as well as Patient-Reported Outcome Measures (PROMs) and Pink Esthetic Scores (PESs) were collected. Results: The data collected indicate a positive trend with regard to peri-implant pocket depth, bleeding and suppuration scores, as well as the peri-implant marginal bone level for the evaluated cases six months postoperatively. PROMs with regard to pain experience varied between 4.5 and 5.9 on the Visual Analogue Scale (VAS). After 12 months, the PES increased in two cases and decreased in one case. Conclusions: This case series provides a comprehensive overview of the surgical reconstructive peri-implantitis treatment using an electrolytic cleaning device, highlighting promising results with regard to the aforementioned parameters. Full article
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