Skip to Content
You are currently on the new version of our website. Access the old version .

303 Results Found

  • Article
  • Open Access

9 November 2026

The type and intensity of ocean background noise vary with time and location. Deployed sensors therefore often encounter noise conditions that differ from those represented in the training and validation data for ship-type recognition. When a sensor...

(This article belongs to the Section Ocean Engineering)
  • Article
  • Open Access
2 Citations
3,487 Views
18 Pages

Knowledge-Enhanced Graph Attention Network for Fact Verification

  • Chonghao Chen,
  • Jianming Zheng and
  • Honghui Chen

15 August 2021

Fact verification aims to evaluate the authenticity of a given claim based on the evidence sentences retrieved from Wikipedia articles. Existing works mainly leverage the natural language inference methods to model the semantic interaction of claim a...

  • Article
  • Open Access
3 Citations
2,901 Views
12 Pages

Conflict Experience Regulates the Neural Encoding of Cognitive Conflict

  • Hui Jiang,
  • Chaozheng Huang,
  • Zekai Li,
  • Qiuyun Wang and ,
  • Weisong Liang and
  • Aibao Zhou
  • + 1 author+ 0 author

Cognitive control is adaptive in that it rapidly adjusts attention in response to changing contexts and shifting goals. Research provides evidence that cognitive control can rapidly adjust attention to focus on task-relevant information based on prio...

(This article belongs to the Section Behavioral Neuroscience)
  • Article
  • Open Access
13 Citations
5,645 Views
14 Pages

Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan

  • Misa Hirose,
  • Paul Schilf,
  • Kim Zarse,
  • Hauke Busch and ,
  • Georg Fuellen,
  • Olaf Jöhren,
  • Rüdiger Köhling,
  • Inke R. König,
  • Barbara Richer and
  • Saleh M. Ibrahim
  • + 10 authors+ 5 authors

13 July 2019

Mitochondrial complex I—the largest enzyme complex of the mitochondrial oxidative phosphorylation machinery—has been proposed to contribute to a variety of age-related pathological alterations as well as longevity. The enzyme complex-cons...

(This article belongs to the Section Human Genomics and Genetic Diseases)
  • Article
  • Open Access
85 Views
20 Pages

2 November 2026

Accurate 3D medical image segmentation requires effective integration of encoder details and decoder semantics. However, their relative contributions vary across decoding stages and spatial locations, and attention based only on the current feature p...

(This article belongs to the Special Issue Evolving Paradigms in Medical Image Analysis: From CNNs to Foundation Models)
  • Article
  • Open Access
1,328 Views
14 Pages

6 November 2025

This study presents a dual-module architecture for image forgery detection in the context of cyber fraud investigation, designed to provide interpretable and court-admissible forensic evidence. The forgery segmentation module built on an encoder&ndas...

(This article belongs to the Special Issue Applied and Innovative Computational Intelligence Systems: 4th Edition)
  • Article
  • Open Access
23 Citations
7,537 Views
11 Pages

Putative Nonribosomal Peptide Synthetase and Cytochrome P450 Genes Responsible for Tentoxin Biosynthesis in Alternaria alternata ZJ33

  • You-Hai Li,
  • Wen-Jin Han,
  • Xi-Wu Gui,
  • Tao Wei and ,
  • Shuang-Yan Tang and
  • Jian-Ming Jin
  • + 1 author+ 0 author

2 August 2016

Tentoxin, a cyclic tetrapeptide produced by several Alternaria species, inhibits the F1-ATPase activity of chloroplasts, resulting in chlorosis in sensitive plants. In this study, we report two clustered genes, encoding a putative non-ribosome peptid...

(This article belongs to the Collection Evolutionary/Phylogenetic Studies of Mycotoxin Biosynthetic Pathways)
  • Review
  • Open Access
9 Citations
6,180 Views
18 Pages

Mitochondrial microRNAs: A Putative Role in Tissue Regeneration

  • Sílvia C. Rodrigues,
  • Renato M. S. Cardoso and
  • Filipe V. Duarte

21 December 2020

The most famous role of mitochondria is to generate ATP through oxidative phosphorylation, a metabolic pathway that involves a chain of four protein complexes (the electron transport chain, ETC) that generates a proton-motive force that in turn drive...

(This article belongs to the Collection Mitochondria and Stress Responses)
  • Review
  • Open Access
28 Citations
9,670 Views
20 Pages

10 March 2022

The ATP synthase is a mitochondrial inner membrane complex whose function is essential for cell bioenergy, being responsible for the conversion of ADP into ATP and playing a role in mitochondrial cristae morphology organization. The enzyme is compose...

(This article belongs to the Special Issue Mitochondrial Function and Signaling to Regulate Cellular Life)
  • Article
  • Open Access
5 Citations
6,485 Views
12 Pages

Stress can modulate episodic memory in various ways. The present study asks how post-encoding stress affects visual context memory. Participants encoded object images centrally positioned on background scenes. After encoding, they were either exposed...

(This article belongs to the Special Issue The Role of Stress and Glucocorticoids in Learning and Memory)
  • Review
  • Open Access
24 Citations
6,945 Views
16 Pages

On the Role of Central Type-1 Cannabinoid Receptor Gene Regulation in Food Intake and Eating Behaviors

  • Mariangela Pucci,
  • Elizabeta Zaplatic,
  • Maria Vittoria Micioni Di Bonaventura,
  • Emanuela Micioni Di Bonaventura and ,
  • Paolo De Cristofaro,
  • Mauro Maccarrone,
  • Carlo Cifani and
  • Claudio D’Addario
  • + 3 authors+ 0 author

Different neuromodulatory systems are involved in long-term energy balance and body weight and, among these, evidence shows that the endocannabinoid system, in particular the activation of type-1 cannabinoid receptor, plays a key role. We here review...

(This article belongs to the Special Issue Endocannabinoid System in Health and Disease: Current Situation and Future Perspectives 3.0)
  • Article
  • Open Access
588 Views
18 Pages

Polarity-Dependent Effects of Sinusoidal Galvanic Vestibular Stimulation on Cardiovascular Responses During Cognitive Load

  • Claudio Zavattaro,
  • Hilary Serra,
  • Emanuele Cirillo,
  • Samuel Cento and ,
  • Roberto Gammeri and
  • Raffaella Ricci
  • + 1 author+ 0 author

29 August 2026

The vestibular system contributes to cardiovascular regulation during changes in gravitational load (e.g., postural transitions, microgravity), in vestibular disorders, and during vestibular stimulations. Studies employing sinusoidal galvanic vestibu...

(This article belongs to the Special Issue Sensing Technologies for Mobile Health Monitoring)
  • Review
  • Open Access
8 Citations
12,753 Views
16 Pages

26 May 2023

What is the significance of a touch encoded by slow-conducted unmyelinated C-tactile (CT) fibers? It is the so-called affiliative touch, which has a fundamental social impact. In humans, it has been demonstrated that the affiliative valence of this k...

  • Article
  • Open Access
9 Citations
3,400 Views
13 Pages

The Attentional Boost Effect in Young and Adult Euthymic Bipolar Patients and Healthy Controls

  • Giulia Bechi Gabrielli,
  • Clelia Rossi-Arnaud,
  • Pietro Spataro,
  • Fabrizio Doricchi and ,
  • Marco Costanzi,
  • Alessandro Santirocchi,
  • Gloria Angeletti,
  • Gabriele Sani and
  • Vincenzo Cestari
  • + 4 authors+ 0 author

6 March 2021

In the Attentional Boost Effect (ABE), stimuli encoded with to-be-responded targets are later recognized more accurately than stimuli encoded with to-be-ignored distractors. While this effect is robust in young adults, evidence regarding healthy olde...

(This article belongs to the Special Issue Predicting Psychopathological Onset: Early Signs of Neuropsychiatric Diseases)
  • Article
  • Open Access
712 Views
33 Pages

27 August 2026

License plate recognition is a critical perception module in intelligent transportation systems, yet severe occlusion remains a fundamental challenge in unconstrained traffic scenes because the missing visual evidence is physically absent rather than...

(This article belongs to the Section Intelligent Sensors)
  • Article
  • Open Access
43 Citations
7,055 Views
15 Pages

GC-MS Profile and Enhancement of Antibiotic Activity by the Essential Oil of Ocotea odorífera and Safrole: Inhibition of Staphylococcus aureus Efflux Pumps

  • Ray S. Almeida,
  • Priscilla R. Freitas,
  • Ana Carolina J. Araújo,
  • Irwin R. Alencar Menezes and ,
  • Eduardo L. Santos,
  • Saulo R. Tintino,
  • Talysson F. Moura,
  • Jaime R. Filho,
  • Vitória A. Ferreira and
  • Henrique D. Melo Coutinho
  • + 10 authors+ 5 authors

Considering the evidence that essential oils, as well as safrole, could modulate bacterial growth in different resistant strains, this study aims to characterize the phytochemical profile and evaluate the antibacterial and antibiotic-modulating prope...

(This article belongs to the Section Novel Antimicrobial Agents)
  • Article
  • Open Access
16 Citations
2,899 Views
12 Pages

21 October 2022

ALSC (Aspect-level Sentiment Classification) is a fine-grained task in the field of NLP (Natural Language Processing) which aims to identify the sentiment toward a given aspect. In addition to exploiting the sentence semantics and syntax, current ALS...

(This article belongs to the Special Issue Advancement of Mathematical Methods in Feature Representation Learning for Artificial Intelligence, Data Mining and Robotics)
  • Article
  • Open Access
4 Citations
4,848 Views
24 Pages

Rat Cytomegalovirus Virion-Associated Proteins R131 and R129 Are Necessary for Infection of Macrophages and Dendritic Cells

  • Iris K. A. Jones,
  • Nicole N. Haese,
  • Philippe Gatault,
  • Zachary J. Streblow and ,
  • Takeshi F. Andoh,
  • Michael Denton,
  • Cassilyn E. Streblow,
  • Kiley Bonin,
  • Craig N. Kreklywich and
  • Daniel N. Streblow
  • + 7 authors+ 2 authors

19 November 2020

Cytomegalovirus (CMV) establishes persistent, latent infection in hosts, causing diseases in immunocompromised patients, transplant recipients, and neonates. CMV infection modifies the host chemokine axis by modulating chemokine and chemokine recepto...

(This article belongs to the Special Issue Cytomegalovirus (CMV) Infection and Latency)
  • Article
  • Open Access
25 Citations
8,398 Views
34 Pages

We propose that ribosomal RNA (rRNA) formed the basis of the first cellular genomes, and provide evidence from a review of relevant literature and proteonomic tests. We have proposed previously that the ribosome may represent the vestige of the first...

(This article belongs to the Special Issue Structure, Function and Evolution of the Ribosome)
  • Article
  • Open Access
1 Citations
759 Views
21 Pages

16 July 2026

Keyword spotting (KWS) systems based on Spike Neural Networks (SNNs) offer a promising solution for always-on voice interfaces. However, achieving a favorable trade-off between computational footprint and recognition accuracy remains challenging for...

(This article belongs to the Section Sensor Networks)
  • Article
  • Open Access
8 Citations
7,119 Views
16 Pages

Neural Modulation of the Primary Auditory Cortex by Intracortical Microstimulation with a Bio-Inspired Electronic System

  • Maria Giovanna Bianco,
  • Salvatore Andrea Pullano,
  • Rita Citraro,
  • Emilio Russo and ,
  • Giovambattista De Sarro,
  • Etienne de Villers Sidani and
  • Antonino S. Fiorillo
  • + 2 authors+ 0 author

Nowadays, the majority of the progress in the development of implantable neuroprostheses has been achieved by improving the knowledge of brain functions so as to restore sensorial impairments. Intracortical microstimulation (ICMS) is a widely used te...

  • Review
  • Open Access
46 Citations
11,099 Views
27 Pages

Sigma-2 Receptors—From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases

  • Britney N. Lizama,
  • Jennifer Kahle,
  • Susan M. Catalano,
  • Anthony O. Caggiano and ,
  • Michael Grundman and
  • Mary E. Hamby
  • + 1 author+ 0 author

There is a large unmet medical need to develop disease-modifying treatment options for individuals with age-related degenerative diseases of the central nervous system. The sigma-2 receptor (S2R), encoded by TMEM97, is expressed in brain and retinal...

(This article belongs to the Special Issue The Intriguing Sigma-1 and Sigma-2 Receptors and Their Potential Therapeutic Roles 2.0)
  • Article
  • Open Access
2 Citations
2,049 Views
18 Pages

In the era of Large Language Models (LLMs), Retrieval-Augmented Generation (RAG) architectures are gaining significant attention for their ability to ground language generation in reliable knowledge sources. Despite their effectiveness, RAG systems b...

(This article belongs to the Section Large Language Models and Embodied Intelligence)
  • Article
  • Open Access
7 Citations
1,697 Views
33 Pages

SwinCAMF-Net: Explainable Cross-Attention Multimodal Swin Network for Mammogram Analysis

  • Lakshmi Prasanthi R. S. Narayanam,
  • Thirupathi N. Rao and
  • Deva S. Kumar

28 November 2025

Background: Breast cancer is a leading cause of cancer-related mortality among women, and earlier diagnosis significantly improves treatment outcomes. However, traditional mammography-based systems rely on single-modality image analysis and lack inte...

(This article belongs to the Special Issue Deep Learning and Multimodal Large Language Models in Tumor/Cancer Diagnosis, Prediction and Prognosis)
  • Article
  • Open Access
1 Citations
1,709 Views
59 Pages

Adaptive Neural Network Method for Detecting Crimes in the Digital Environment to Ensure Human Rights and Support Forensic Investigations

  • Serhii Vladov,
  • Oksana Mulesa,
  • Petro Horvat,
  • Yevhen Kobko and ,
  • Victoria Vysotska,
  • Vasyl Kikinchuk,
  • Serhii Khursenko,
  • Kostiantyn Karaman and
  • Oksana Kochan
  • + 4 authors+ 0 author

2 March 2026

This article presents an adaptive neural network method for the automated detection, reconstruction, and prioritisation of multi-stage criminal operations in the digital environment, aiming to protect human rights and ensure the legal security of dig...

  • Review
  • Open Access
719 Views
24 Pages

Rewriting Phosphorylation Codes: Toward Signal-State Editing with PhosTACs

  • Dong-Ting Ke,
  • Wei-Chen Chang,
  • Yu-Yu Chen and
  • Po-Han Chen

Protein phosphorylation is a dynamic post-translational modification (PTM) that regulates protein function, signaling, and cellular behavior. Accumulating evidence indicates that combinations of phosphosites function as “phosphorylation codes,&...

  • Article
  • Open Access
17 Views
19 Pages

4 November 2026

Circular RNAs (circRNAs) participate in gene regulation and disease-associated processes. Computational prediction of circRNA–disease associations (CDAs) can help prioritize candidates for biological investigation. Here, we propose a multi-view...

(This article belongs to the Special Issue Applications of Gene Expression Profiling in Human Disease)
  • Article
  • Open Access
469 Views
24 Pages

21 August 2026

To address the challenges of multi-scale target variation, complex background interference, and insufficient feature fusion quality in maritime remote sensing ship detection, this paper proposes MarShip-DET, a frequency-aware multi-scale fusion detec...

(This article belongs to the Section Remote Sensors)
  • Article
  • Open Access
10 Citations
3,436 Views
12 Pages

Marek’s Disease Virus Cluster 3 miRNAs Restrict Virus’ Early Cytolytic Replication and Pathogenesis

  • Yifei Liao,
  • Guoqing Zhuang,
  • Aijun Sun,
  • Owais A. Khan and ,
  • Blanca Lupiani and
  • Sanjay M. Reddy
  • + 1 author+ 0 author

17 November 2020

Herpesvirus-encoded microRNAs (miRNAs) have been discovered in infected cells; however, lack of a suitable animal model has hampered functional analyses of viral miRNAs in vivo. Marek’s disease virus (MDV) (Gallid alphaherpesvirus 2, GaHV-2) ge...

(This article belongs to the Special Issue Animal Herpesviruses Pathogenesis and Immunity)
  • Review
  • Open Access
29 Citations
4,877 Views
15 Pages

Regulation of Latency and Reactivation by Human Cytomegalovirus miRNAs

  • Nicole L. Diggins,
  • Rebecca L. Skalsky and
  • Meaghan H. Hancock

13 February 2021

Human cytomegalovirus (HCMV) encodes 22 mature microRNAs (miRNAs), which regulate a myriad of cellular processes, including vesicular trafficking, cell cycle progression, apoptosis, and immune evasion, as well as viral gene expression. Recent evidenc...

(This article belongs to the Special Issue Cytomegalovirus (CMV) Infection and Latency)
  • Review
  • Open Access
218 Views
33 Pages

2 October 2026

Reticulocalbin-2 (RCN2), encoded by the human RCN2 gene (HGNC:9935) and historically identified as E6-binding protein, is a CREC-family EF-hand Ca2+-binding protein. Although first characterized as an endoplasmic reticulum (ER)-associated protein, cu...

(This article belongs to the Special Issue Feature Papers: Molecular Genetics and Genomics 2026)
  • Review
  • Open Access
52 Citations
6,718 Views
22 Pages

CFTR Modulator Therapies: Potential Impact on Airway Infections in Cystic Fibrosis

  • Francesca Saluzzo,
  • Luca Riberi,
  • Barbara Messore,
  • Nicola Ivan Loré and ,
  • Irene Esposito,
  • Elisabetta Bignamini and
  • Virginia De Rose
  • + 2 authors+ 0 author

6 April 2022

Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding for the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein, expressed on the apical surface of epithelial cells. CFTR absence/dysfunction...

(This article belongs to the Collection Cystic Fibrosis: Cells, Physiopathology and Emerging Therapies)
  • Article
  • Open Access
2,473 Views
11 Pages

A Multi-Hop Reasoning Knowledge Selection Module for Dialogue Generation

  • Zhiqiang Ma,
  • Jia Liu,
  • Biqi Xu,
  • Kai Lv and
  • Siyuan Guo

19 August 2024

Knowledge selection plays a crucial role in knowledge-driven dialogue generation methods, directly influencing the accuracy, relevance, and coherence of generated responses. Existing research often overlooks the handling of disparities between dialog...

(This article belongs to the Special Issue New Advances in Affective Computing)
  • Article
  • Open Access
558 Views
29 Pages

Medical image segmentation still faces three critical challenges: insufficient joint modeling of local details and long-range dependencies, the high computational burden of transformer-based architectures for high-resolution inputs, and performance d...

(This article belongs to the Special Issue AI-Driven Medical Image/Video Processing)
  • Review
  • Open Access
16 Citations
11,175 Views
20 Pages

Novel Approaches to Investigate One-Carbon Metabolism and Related B-Vitamins in Blood Pressure

  • Amy McMahon,
  • Helene McNulty,
  • Catherine F. Hughes,
  • J. J. Strain and
  • Mary Ward

11 November 2016

Hypertension, a major risk factor for heart disease and stroke, is the world’s leading cause of preventable, premature death. A common polymorphism (677C→T) in the gene encoding the folate metabolizing enzyme methylenetetrahydrofolate reductase (MTHF...

(This article belongs to the Special Issue B-Vitamins and One-Carbon Metabolism)
  • Review
  • Open Access
862 Views
22 Pages

Subcortical Dendritic Scaffolding in Autism Spectrum Disorder: A Testable ANK2–SCN2A–SHANK Framework

  • Sara Cacciato-Salcedo,
  • Ana Belén Lao-Rodriguez,
  • Marija M. Petrinovic and
  • Manuel S. Malmierca

The autism spectrum disorder-associated SCN2A, ANK2, and SHANK-family genes encode molecularly distinct proteins that converge functionally on dendritic integration. Recent work established that ankyrin-B, encoded by ANK2, acts as an obligate dendrit...

(This article belongs to the Special Issue Unraveling Neurodevelopmental Disorders: A Molecular Perspective)
  • Article
  • Open Access
2 Citations
1,493 Views
23 Pages

16 July 2025

To solve the issue that existing yield prediction methods do not fully capture the interaction between multiple factors, we propose a winter wheat yield prediction framework with triple cross-attention for multi-source data fusion. This framework con...

(This article belongs to the Section Plant Modeling)
  • Review
  • Open Access
7 Citations
5,086 Views
12 Pages

The Functional Roles and Regulation of Circular RNAs during Cellular Stresses

  • Yueh-Chun Lee,
  • Wei-Yu Wang,
  • Hui-Hsuan Lin,
  • Yi-Ren Huang and ,
  • Ya-Chi Lin and
  • Kuei-Yang Hsiao
  • + 1 author+ 0 author

Circular RNAs (circRNAs) are a novel class of regulatory RNA involved in many biological, physiological and pathological processes by functioning as a molecular sponge, transcriptional/epigenetic/splicing regulator, modulator of protein–protein...

(This article belongs to the Section Evolution of Non-Coding RNA)
  • Review
  • Open Access
112 Citations
18,909 Views
37 Pages

Microtubule Dysfunction: A Common Feature of Neurodegenerative Diseases

  • Antonella Sferra,
  • Francesco Nicita and
  • Enrico Bertini

5 October 2020

Neurons are particularly susceptible to microtubule (MT) defects and deregulation of the MT cytoskeleton is considered to be a common insult during the pathogenesis of neurodegenerative disorders. Evidence that dysfunctions in the MT system have a di...

(This article belongs to the Section Molecular Neurobiology)
  • Article
  • Open Access
2 Citations
2,524 Views
24 Pages

10 December 2023

The vesicle-associated membrane protein 7 (VAMP7) is a SNARE protein of the longin family involved in a wide range of subcellular trafficking events, including neurite sprouting and elongation. The expression of the human gene SYBL1, encoding VAMP7,...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
2 Citations
2,134 Views
13 Pages

Effects of Faces and Voices on the Encoding of Biographic Information

  • Sarah Fransson,
  • Sherryse Corrow,
  • Shanna Yeung,
  • Heidi Schaefer and
  • Jason J. S. Barton

15 December 2022

There are multiple forms of knowledge about people. Whether diverse person-related data interact is of interest regarding the more general issue of integration of multi-source information about the world. Our goal was to examine whether perception of...

(This article belongs to the Special Issue People Recognition through Face, Voice, Name and Their Interactions)
  • Article
  • Open Access
8 Citations
3,265 Views
16 Pages

The WRKY28-BRC1 Transcription Factor Module Controls Shoot Branching in Brassica napus

  • Ka Zhang,
  • Jinfang Zhang,
  • Cheng Cui,
  • Liang Chai and ,
  • Benchuan Zheng,
  • Liangcai Jiang and
  • Haojie Li
  • + 2 authors+ 0 author

6 February 2025

The trade-off between growth and defense is common in plants. We previously demonstrated that BnaA03.WRKY28 weakened resistance strength but promoted shoot branching in Brassica napus (rapeseed). However, the molecular mechanism by which WRKY28 promo...

(This article belongs to the Special Issue Advancement in Gene Expression Regulation in Plants: Coordinating Growth, Development, and Stress Resilience)
  • Article
  • Open Access
7 Citations
3,430 Views
14 Pages

Interaction of Fabry Disease and Diabetes Mellitus: Suboptimal Recruitment of Kidney Protective Factors

  • Maria D. Sanchez-Niño,
  • Maria I. Ceballos,
  • Sol Carriazo,
  • Aranzazu Pintor-Chocano and ,
  • Ana B. Sanz,
  • Moin A. Saleem and
  • Alberto Ortiz
  • + 2 authors+ 0 author

1 November 2023

Fabry disease is a lysosomal disease characterized by globotriaosylceramide (Gb3) accumulation. It may coexist with diabetes mellitus and both cause potentially lethal kidney end-organ damage. However, there is little information on their interaction...

(This article belongs to the Section Molecular Endocrinology and Metabolism)
  • Article
  • Open Access
1 Citations
841 Views
27 Pages

Eye-Movement-Assisted Time–Frequency EEG Decoding for Multimodal Robotic Arm Control

  • Xiangyang Sun,
  • Wenjun Zhang,
  • Jiahua Wu,
  • Xingwei Xiong and
  • Haixia Mei

Brain–computer interface (BCI) technology has shown potential for future rehabilitation-related and assistive control applications. Nevertheless, single-modality electroencephalography-based motor imagery (EEG-MI) signals are susceptible to interfere...

  • Review
  • Open Access
23 Citations
5,974 Views
22 Pages

19 May 2021

Hepatitis C virus (HCV) genome encodes for one long polyprotein that is processed by cellular and viral proteases to generate 10 polypeptides. The viral structural proteins include the core protein, and the envelope glycoproteins E1 and E2, present a...

(This article belongs to the Special Issue Hepatitis C Virus and Hepatocellular Carcinoma (HCV & HCC))
  • Article
  • Open Access
10 Citations
3,133 Views
24 Pages

28 January 2022

The role of aminoacyl-tRNA synthetases (aaRS) in the emergence and evolution of genetic coding poses challenging questions concerning their provenance. We seek evidence about their ancestry from curated structure-based multiple sequence alignments of...

(This article belongs to the Special Issue Peptide and Protein Conformational Features and Biological Activity)
  • Article
  • Open Access
15 Citations
4,351 Views
20 Pages

Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin System

  • Graham J. Moore,
  • Harry Ridgway,
  • Konstantinos Kelaidonis,
  • Christos T. Chasapis and ,
  • Irene Ligielli,
  • Thomas Mavromoustakos,
  • Joanna Bojarska and
  • John M. Matsoukas
  • + 3 authors+ 0 author

29 July 2022

Angiotensin receptor blockers (ARBs) used in the treatment of hypertension and potentially in SARS-CoV-2 infection exhibit inverse agonist effects at angiotensin AR1 receptors, suggesting the receptor may have evolved to accommodate naturally occurri...

(This article belongs to the Special Issue Advances in Research of Short Peptides II)
  • Article
  • Open Access
1 Citations
1,951 Views
16 Pages

12 November 2025

Background/Objectives: Antimicrobial resistance (AMR) in Klebsiella pneumoniae poses a serious threat to healthcare, especially in sub-Saharan Africa (SSA). To complement AMR infection control in Kenya, here, clinical and environmental genomes were i...

(This article belongs to the Section Bacteriophages)
  • Article
  • Open Access
4 Citations
2,531 Views
24 Pages

Identification and Characterization of an HtrA Sheddase Produced by Coxiella burnetii

  • Ikram Omar Osman,
  • Aurelia Caputo,
  • Lucile Pinault,
  • Jean-Louis Mege and ,
  • Anthony Levasseur and
  • Christian A. Devaux
  • + 1 author+ 0 author

Having previously shown that soluble E-cadherin (sE-cad) is found in sera of Q fever patients and that infection of BeWo cells by C. burnetii leads to modulation of the E-cad/β-cat pathway, our purpose was to identify which sheddase(s) might cat...

(This article belongs to the Section Molecular Microbiology)
  • Article
  • Open Access
2 Citations
4,076 Views
25 Pages

Gabor Frames and Deep Scattering Networks in Audio Processing

  • Roswitha Bammer,
  • Monika Dörfler and
  • Pavol Harar

26 September 2019

This paper introduces Gabor scattering, a feature extractor based on Gabor frames and Mallat’s scattering transform. By using a simple signal model for audio signals, specific properties of Gabor scattering are studied. It is shown that, for ea...

(This article belongs to the Special Issue Harmonic Analysis and Applications)

of 7