Coat protein I (COPI) is necessary for intra-Golgi transport and retrograde transport from the Golgi apparatus back to the endoplasmic reticulum. The key component of the COPI coat is the coatomer complex, which is composed of seven subunits (α...
K2P channels, also known as two-pore domain K+ channels, play a crucial role in maintaining the cell membrane potential and contributing to potassium homeostasis due to their leaky nature. The TREK, or tandem of pore domains in a weak inward rectifyi...
A vital procedure for eliminating moisture from the air, dehumidification is necessary for processes like desalination and air conditioning. The Peltier dehumidifier, sometimes referred to as a thermoelectric dehumidifier, removes moisture using the...
Copper ions serve as essential cofactors for many enzymes but exhibit toxicity at elevated concentrations. In Gram-negative bacteria, the Cop system, typically encoded by copABCD, plays a crucial role in maintaining copper homeostasis and detoxificat...
The game of pursuit and evasion, when played on graphs, is often referred to as the game of cops and robbers. This classical version of the game has been completely solved by Nowakowski and Winkler, who gave the exact class of graphs for which the pu...
The center of pressure (CoP) is one of the most utilized quantitative measurements describing postural competency. Due to the complexity and biological variability of postural regulatory systems, a myriad of different methods and parameters have been...
A Cop and Drunken Robber (CDR) game is one variation of a famous combinatorial game, called Cops and Robbers, which has been extensively studied and applied in the area of theoretical and computer science as demonstrated by several conferences and pu...
Compared to mechanical compressors, ejector-based refrigeration systems can make direct use of many forms of thermal energy, including waste heat, solar thermal, or biogases. It is known that SE systems have a lower thermal efficiency compared to mec...
This study proposes a real-time chiller capacity control strategy based on marginal Coefficient of Performance (COP) analysis to improve the energy efficiency of air-conditioning systems. The research focuses on the air-conditioning system (ACS) of a...
Mature astrocytes are characterized by a K+ conductance (passive conductance) that changes with a constant slope with voltage, which is involved in K+ homeostasis in the brain. Recently, we reported that the tandem of pore domains in a weak inward re...
Protecting the quality of the groundwater is of the utmost importance, particularly in countries such as Jordan, where the groundwater comprises a significant portion of the total water resources. A groundwater vulnerability assessment is one of the...
A biomechanical understanding of gait stability is needed to reduce falling risk. As a typical parameter, the COM-COP (center of mass–center of pressure) inclination angle (IA) could provide valuable insight into postural control and balance re...
Aging causes foot arches to collapse, possibly leading to foot deformities and falls. This paper proposes a set of measures involving an entropy-based method used for two groups of young adults with dissimilar foot arches to explore and quantize post...
Balance is a fundamental quality for trampoline athletes, the basis for completing complex skills. We aimed to compare balance control strategies between elite trampolinists (ETs) and sub-elite trampolinists (Sub-ET) by integrating linear and nonline...
Green bonds are a relatively new financial product that offers investors a variety of alternatives. However, many individuals continue to be suspicious about its long-term returns and risks. To clarify this issue, this study employed two global envir...
As the global energy trend continues, the importance of energy savings and efficient use is being emphasized, and the installation and operation of geothermal heat pump systems is increasing. In many buildings, where an actual geothermal heat pump sy...
Background: This study aimed to investigate how barbell type (elastic vs. inelastic) and lifting speed affect postural stability and lower limb muscle activation during the single-leg deadlift (SLDL), a common unilateral exercise in rehabilitation an...
As the world data traffic increasingly grows, the need for computer room air conditioning (CRAC)-type equipment grows proportionally. The air conditioning equipment is responsible for approximately 38% of the energy consumption of data centers. The e...
The urgency of addressing climate change is increasingly evident through the rise in devastating natural disasters and significant shifts in global temperatures. With the urbanization of rural landscapes to accommodate population growth, the built en...
As an alternative to high-cost shoe insole pressure sensors that measure the insole pressure distribution and calculate the center of pressure (CoP), researchers developed a foot sensor with FSR sensors on the bottom of the insole. However, the calcu...
Parkinson’s disease (PD) impairs balance and gait through neuromotor dysfunction, yet conventional assessments often overlook subtle postural deficits during dynamic tasks. This study evaluated the diagnostic utility of center-of-pressure (CoP)...
In this paper, we proposed an improved (Indum-Galum-Zinc-Oxide) IGZO-Filler (IF) structure that can be used in a Cell-On-Peri (COP) structure by improving the excellent erase performance of the IGZO-Pillar (IP) structure. The IP structure mentioned a...
Ejector-based refrigeration systems can make direct use of many forms of thermal energy, such as solar thermal, waste heat, biogas, or natural gas. The present paper describes the estimation of the thermal coefficient of performance (COP) of a binary...
Plant sterols (PS) are oxidized to PS oxidation products (POP). This study quantified the change in serum POP compared to cholesterol oxidation products (COP) after the intake of increasing POP doses. This was a double-blind, randomized, placebo-cont...
1 September 2022
Development of platinum resistance is one of the major causes of epithelial ovarian cancer (EOC) treatment failure. COP9 signalosome subunit 5 (COPS5) was found to take part in the progression of EOC in our previous study. Herein, we aim to uncover t...
In this study, we investigate the optimization of ring spinning parameters affecting key yarn quality characteristics, including yarn tension, cop diameter, and end breakage. Experiments were conducted on cotton–polyester yarn using three proce...
Streptococcus suis is a zoonotic pathogen that causes great economic losses to the swine industry and severe threats to public health. A better understanding of its physiology would contribute to the control of its infections. Although copper is an e...
The tumour suppressor p53 is essential for maintaining DNA integrity, and plays a major role in cellular senescence and aging. Understanding the mechanisms that contribute to p53 dysfunction can uncover novel possibilities for improving cancer therap...
The synthesis of anthocyanin in pear (Pyrus bretschneideri) fruit is regulated by light. However, little is known about the molecular mechanisms of pear fruit coloring mediated by upstream light-signaling regulators. Here, the photoresponse factors C...
The ability to maintain postural stability is essential in our daily lives. Relatedly, hemiparetic stroke patients have a very high risk of falls. This study aimed to improve the traditional rehabilitation treatment for stroke patients with hemipares...
The COP9 (Constitutive photomorphogenesis 9) signalosome (CSN) is a highly conserved protein complex that influences several signaling and developmental processes. The COP9 signalosome consists of eight subunits, among which two subunits, CSN5 and CS...
Light is an important environmental signal that governs plant growth, development, and metabolism. Constitutive photomorphogenic 1 (COP1) is a light signaling component that plays a vital role in plant light responses. We isolated the COP1 gene (LoCO...
This study examines how public conversation on X unfolded during the COP30 climate summit, focusing on posts articulated around the official hashtag #COP30noBrasil and analysing a dataset of 1139 posts. Social media research has shown that platforms...
Aberrant activation of the mitogen-activated protein kinase (MAPK) cascade promotes oncogenic transcriptomes. Despite efforts to inhibit oncogenic kinases, such as BRAFV600E, tumor responses in patients can be heterogeneous and limited by drug resist...
In Arabidopsis, CONSTITUTIVE PHOTOMORPHOGENIC/DE-ETIOLATED/FUSCA (COP/DET/FUS) genes act in repression of photomorphogenesis in darkness, and recent reports revealed that some of these genes, such as COP1 and DET1, also have important roles in contro...
Heat stress inhibits cell proliferation as well as animal production. Here, we aimed to demonstrate that 9-mer disulfide dimer peptide (CopA3) supplementation stabilizes porcine muscle satellite cell (PMSC) proliferation and heat shock protein (HSP)...
Drosophila melanogaster (the fruit fly) is a valuable experimental platform for modeling host–pathogen interactions. It is also commonly used to define innate immunity pathways and to understand the mechanisms of both host tolerance to commensa...
Glioblastoma (GBM) is a highly aggressive primary malignant brain tumor, featuring diffuse infiltrative growth and poor clinical outcomes, which underscores the need to delineate the molecular mechanisms driving its malignant progression. COP9 signal...
In this study, TpDMB-COPs, a specific class of covalent organic polymers (COPs), was synthesized using Schiff-base chemistry and incorporated into a polyvinylidene fluoride (PVDF) polymer for the first time to prepare COPs mixed matrix membranes (TpD...
The morphogenesis of crops is critical to their yield performance. COP1 (constitutively photomorphogenic1) is one of the core regulators in plant morphogenesis and has been deeply studied in Arabidopsis thaliana. However, the function of COP1 in maiz...
Ultraviolet (UV) exposure is well-known to induce premature aging, which is mediated by matrix metalloproteinase-1 (MMP-1) activity. A 9-mer peptide, CopA3 (CopA3) was synthesized from a natural peptide, coprisin, which is isolated from the dung beet...
This essay applies close textual analysis to news reports covering the 20 November 2025 fire at the United Nations COP30 meeting in Belém, Brazil, to demonstrate how allegory can manifest in journalistic reporting of real-world events. It argu...
COP1/SPA1 complex in Arabidopsis inhibits photomorphogenesis through the ubiquitination of multiple photo-responsive transcription factors in darkness, but such inhibiting function of COP1/SPA1 complex would be suppressed by cryptochromes in blue lig...
In the practical operation of air-source heat pump heating systems coupled with phase-change energy storage tanks, wide fluctuations in outdoor temperatures often cause issues such as excessive heating, frequent unit start–stops, and low operat...
Buffaloes are vital livestock in South-East Asia, attributed to their adaptation to hot and humid climates as well as their capacity to produce high-quality milk and meat. However, the texture of buffalo meat is suboptimal and its slow growth rate re...
RING-finger-type ubiquitin E3 ligase Constitutively Photomorphogenic 1 (COP1) and floral integrators such as FLOWERING LOCUS T (FT), TWIN SISTER OF FT (TSF) and SUPPRESSOR OF OVEREXPRESSION OF CONSTANS1 (SOC1) have been identified as regulators of st...
Evaporative systems are probably the oldest technology for thermal comfort. However, they are still an essential technology in the food industry, environments for thermal comfort, and even for cooling data centers. Standards have been improved to com...
The synthesis of anthocyanin pigments in plants is known to be regulated by multiple mechanisms, including epigenetic regulation; however, the contribution of the RNA-directed DNA methylation (RdDM) pathway is not well understood. Here, we used bisul...
Research on Colombians’ knowledge, attitudes, and perceptions (KAP) of biodiversity in the context of COP16 is vital due to Colombia’s significant biodiversity, which comprises about 10% of the world’s total. Understanding public aw...
This Special Issue focuses on proposing and analyzing systemic interdisciplinary approaches to support collaborative strategies and agreed-upon global sustainability policies toward addressing the challenges that lie ahead for our planet’s futu...
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